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Theoretical elastoplastic analysis for foundations with geosynthetic-encased columns

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2012年第7期13卷 506-518页

作者： yuan-yu DUAN Yi-ping ZHANG Dave CHAN ya-nan yu College of Civil Engineering and Architecture Zhejiang UniversityHangzhou 310058China Department of Civil and Environmental Engineering University of AlbertaEdmontonAlbertaCanada

As a new technique in ground improvement, geosynthetic-encased columns (GECs) have promising applications in soft soil foundation. By assuming yielding occurs in the columns while the surrounding soil and the geosynthetic remain elastic, an elastoplastic analytical procedure for foundations improved by GECs is proposed. The radial stresses that the geosynthetic provides and the elastoplastic deformations of the foundation resting on a rigid base are derived. A comparison with finite element analysis shows that the proposed method is effective and can provide a reasonable prediction of a GEC's deformation. Subsequent parametric analysis indicates that higher geosynthetic stiffness leads to better performance of the composite foundation. The optimum length of encasement is related to the load acting on the foundation and the permissible vertical and radial displacements of the column. Moreover, as the dilation angle of the column increases, the settlement decreases, especially under high loading. The influence of the encasement is more significant in soils with smaller elastic modulus.

关键词： Geosynthetic-encased columns (GECs) Equal vertical strain Elastoplastic deformation Analytical procedure

Simulation of filling construction of permeable geosynthetic tubes

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2010年第6期11卷 425-431页

作者： Wei-chao LIU Yi-ping ZHANG Tao LI ya-nan yu College of Civil Engineering and Architecture Zhejiang University Hangzhou 310058 China Zhejiang Water Conservancy and Hydropower College Hangzhou 310018 China

The filling construction of permeable geosynthetic tubes is ***,an analytical approach is developed to determine the internal pressure,tension and shape of the cross section of a geosynthetic tube based on its *** analytical solution for the drainage rate of the tube is then *** course of the filling construction is divided into several time intervals and the volume of the tube after each interval is obtained from the equilibrium of flow calculated from the drainage rate and filling *** validity of our analytical approach is tested by comparing our results with previously published experimental *** results of this comparison indicate that our method is applicable for simulating the filling construction of permeable geosynthetic tubes.

关键词： Geosynthetic tube Filling construction Simulation Volume of the tube Drainage rate

Over-expression of programmed death-ligand 1 and programmed death-1 on antigen-presenting cells as a predictor of organ dysfunction and mortality during early sepsis: a prospective cohort study

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World Journal of Emergency Medicine 2023年第3期14卷 179-185页

作者： Jia-bao Li Miao-rong Xie Mei-li Duan ya-nan yu Chen-chen Hang Zi-ren Tang Chun-sheng Li Department of Critical Care Medicine Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Emergency and Critical Care Center Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Department of Emergency Medicine Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100020China

BACKGROUND:This study aimed to explore the changes of programmed death-ligand 1(PDL1)and programmed death-1(PD-1)expression on antigen-presenting cells(APCs)and evaluate their association with organ failure and mortality during early ***:In total,40 healthy controls and 198 patients with sepsis were included in this *** blood was collected within the first 24 h after the diagnosis of *** expression of PDL1 and PD-1 was determined on APCs,such as B cells,monocytes,and dendritic cells(DCs),by flow *** in plasma,such as interferon-γ(IFN-γ),tumor necrosis factor-α(TNF-α),interleukin-4(IL-4),IL-6,IL-10,and IL-17A were determined by Luminex ***:PD-1 expression decreased significantly on B cells,monocytes,myeloid DCs(mDCs),and plasmacytoid DCs(pDCs)as the severity of sepsis ***-1 expression was also markedly decreased in non-survivors compared with *** contrast,PD-L1 expression was markedly higher on mDCs,pDCs,and monocytes in patients with sepsis than in healthy controls and in non-survivors than in *** PD-L1 expression on APCs(monocytes and DCs)was weakly related to organ dysfunction and infl *** area under the receiver operating characteristic curve(AUC)of the PD-1 percentage of monocytes(monocyte PD-1%)+APACHE II model(0.823)and monocyte PD-1%+SOFA model(0.816)had higher prognostic value than other parameters *** PD-1%was an independent risk factor for 28-day ***:The severity of sepsis was correlated with PD-L1 or PD-1 over-expression on ***-L1 in monocytes and DCs was weakly correlated with infl ammation and organ dysfunction during early *** combination of SOFA or APACHE II scores with monocyte PD-1%could improve the prediction ability for mortality.

关键词： Infl ammation Programmed death-ligand 1 Programmed death-1 Antigen-presenting cells

Lymphangiomatosis associated with protein losing enteropathy:A case report

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World Journal of Clinical Cases 2021年第15期9卷 3758-3764页

作者： Xue-Li Ding Xiao-yan Yin ya-nan yu yun-Qing Chen Wei-Wei Fu Hua Liu Department of Gastroenterology The Affiliated Hospital of Qingdao UniversityQingdao 266003Shandong ProvinceChina Department of Pathology The Affiliated Hospital of Qingdao UniversityQingdao 266003Shandong ProvinceChina

BACKGROUND Lymphangiomatosis is a multisystem disorder that is rarely localized to the gastrointestinal *** usually has no specific clinical presentation and is easily misdiagnosed.A case report and review of the literature on lymphangiomatosis associated with protein-losing enteropathy will help to improve the overall understanding of this *** SUMMARY We report a case of lymphangiomatosis of the bowel and other solid organs.A 78-year-old man presented with recurrent bowel bleeding and protein-losing enteropathy,as well as cystic lesions in the spleen,liver,and *** examinations revealed many cystic lesions on the spleen,liver,kidney,and thickened wall of the ascending colon,as well as pleural effusion and *** revealed a strawberry mucosa,variable spontaneous bleeding,and surface erosion located in the terminal *** cystic masses with a translucent and smooth surface as well as diffuse white spots were located in the colon.A laterally spreading tumor(LST)was located in the ascending *** indicated highly differentiated adenocarcinoma(LST)and lymphangiomatoid dilation,and D2-40 was *** final diagnosis was *** patient underwent surgery for LST and then was administered thalidomide 75-150 mg/*** condition,however,did not *** eventually died 6 mo after the initial *** Lymphangiomatosis usually occurs diffusely and can involve many organs,such as the spleen,kidney,liver,lung,mesentery,and *** bowel bleeding or protein-losing enteropathy is an important indicator that should alert clinicians about the possibility of this disease when it afflicts the *** should improve the medical understanding of lymphangiomatosis.

关键词： Lymphangioma Gastrointestinal hemorrhage Protein-losing enteropathies Colonic neoplasms Small intestine Case report

Feasibility of endoscopic treatment and predictors of lymph node metastasis in early gastric cancer

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World Journal of Gastroenterology 2019年第35期25卷 5344-5355页

作者： yu-Ning Chu ya-nan yu Xue Jing Tao Mao yun-Qing Chen Xiao-Bin Zhou Wen Song Xian-Zhi Zhao Zi-Bin Tian Department of Gastroenterology the Affiliated Hospital of Qingdao University Qingdao 266003 Shandong Province China Department of Pathology the Affiliated Hospital of Qingdao University Qingdao 266003 Shandong Province China Department of Epidemiology and Health Statistics School of Public Health Qingdao University Qingdao 266021 Shandong Province China Endoscopy Center the Affiliated Hospital of Qingdao University Qingdao 266003 Shandong Province China

BACKGROUND Endoscopic submucosal dissection (ESD) has been routinely performed in applicable early gastric cancer (EGC) patients as an alternative to conventional surgical operations that involve lymph node dissection. The indications for ESD have been recently expanded to include larger, ulcerated, and undifferentiated mucosal lesions, and differentiated lesions with slight submucosal invasion. The risk of lymph node metastasis (LNM) is the most important consideration when deciding on a treatment strategy for EGC. Despite the advantages over surgical procedures, lymph nodes cannot be removed by ESD. In addition, whether patients who meet the expanded indications for ESD can be managed safely remains controversial. AIM To determine whether the ESD indications are applicable to Chinese patients and to investigate the predictors of LNM in EGC. METHODS We retrospectively analyzed 12552 patients who underwent surgery for gastric cancer between June 2007 and December 2018 at the Affiliated Hospital of Qingdao University. A total of 1262 (10.1%) EGC patients were eligible for inclusion in this study. Data on the patients’ clinical, endoscopic, and histopathological characteristics were collected. The absolute and expanded indications for ESD were validated by regrouping the enrolled patients and determining the positive LNM results in each subgroup. Predictors of LNM in patients were evaluated by univariate and multivariate analyses. RESULTS LNM was observed in 182 (14.4%) patients. No LNM was detected in the patients who met the absolute indications (0/90). LNM occurred in 4/311 (1.3%) patients who met the expanded indications. According to univariate analysis, LNM was significantly associated with positive tumor marker status, medium (20-30 mm) and large (>30 mm) lesion sizes, excavated macroscopic-type tumors, ulcer presence, submucosal invasion (SM1 and SM2), poor differentiation, lymphovascular invasion (LVI), perineural invasion, and diffuse and mixed Lauren’s type

关键词： Early gastric cancer Lymph node metastasis Predictors Endoscopic submucosal dissection Expanded indications

Gastric adenocarcinoma of fundic gland type after Helicobacter pylori eradication:A case report

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World Journal of Clinical Cases 2019年第13期7卷 1696-1702页

作者： ya-nan yu Xiao-yan Yin Qi Sun Hua Liu Qi Zhang yun-Qing Chen Qing-Xi Zhao Zi-Bin Tian Department of Gastroenterology the Affiliated Hospital of Qingdao University Qingdao 266003 Shandong Province China Department of Pathology the Affiliated Drum Tower Hospital of Nanjing University Medical School Nanjing 210008 Jiangsu Province China Department of Pathology the Affiliated Hospital of Qingdao University Qingdao 266003 Shandong Province China

BACKGROUND Gastric adenocarcinoma of fundic gland type (GA-FG) has recently been proposed as a novel histological type of gastric cancer. CASE SUMMARY We report a case of GA-FG in a 77-year-old Chinese woman with epigastric distention who was referred to endoscopy for the management of an incidentally found submucosal tumor-like elevated lesion in the lower part of the gastric body. The tumor occurred after Helicobacter pylori (H. pylori) eradication therapy without long-term use of proton pump inhibitors. Complete and curable removal of the tumor was performed by endoscopic submucosal dissection. Histopathological findings showed numerous cells with basophilic cytoplasm and mildly atypical nuclei-like chief cells of the fundic gland. The tumor was observed to have the so-called “endless glands” pattern of the well-differentiated mixed phenotype. A safe resection margin without lymphatic and venous invasion was observed. As the tumor occurred after H. pylori eradication therapy, it is unknown whether there was a relationship with H. pylori eradication. The patient will be followed up by periodic gastroscopic observation. CONCLUSION In conclusion, we report a case of GA-FG after H. pylori eradication therapy without long-term proton pump inhibitors use. Further analysis of similar cases will reveal the clinical behavior of GA-FG.

关键词： Gastric adenocarcinoma Fundic gland Helicobacter pylori Eradication Case report

Effect of Cr_(2)O_(3) on properties of CaO-SiO_(2)-Fe_(t)O-MgO system and dissolution behavior of lime

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Journal of Iron and Steel Research International 2024年第4期31卷 870-881页

作者： Shan-nan Li Jian-li Li yue yu Hang-yu Zhu The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081HubeiChina Hubei Provincial Key Laboratory for New Processes of Ironmaking and Steelmaking Wuhan University of Science and TechnologyWuhan 430081HubeiChina Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan 430081HubeiChina

The productivity of the chrome-containing semi-steel converter smelting process is directly affected by the slag-forming speed during the converter preliminary *** effects of Cr_(2)O_(3) content on the physicochemical properties of the CaO-SiO_(2)-Fe_(t)O-MgO system,such as melting temperature,solidification behavior,mineral composition,and lime dissolution rate,were *** results showed that the slag was an amorphous phase at 1500℃.When Cr_(2)O_(3) was added,Ca(Fe,Mg)Si_(2)O_(6) and spinel were formed in the *** the increase in Cr_(2)O_(3) content,the amount of spinel precipitation increased,and the dendritic FegO_(4) crystal gradually changed into the granular(Fe,Mg)(Fe,Cr)2O_(4) *** the Cr_(2)O_(3) content increased from O to 2.91 wt.%,the melting temperature of the slag rose,and the melting range of the slag expanded slightly,but the lime dissolution rate did not *** the Cr_(2)O_(3) content further increased to 9.09 wt.%,the melting temperature continued to rise,the melting range rapidly expanded,and the lime dissolution rate decreased.

关键词： Cr_(2)O_(3) Vanadium-titanium magnetite Converter Slag Lime dissolution

One more step to realistic CO_(2) reduction reactions——geometric structures evolutions at gas-solid interface

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Rare Metals 2024年第2期43卷 849-852页

作者： ya-Qiang Xie Xin yu Ting Wang College of the Environment and Ecology Xiamen UniversityXiamen361102China

A rational design of copper(Cu)nanocatalyst is critical to the efficient carbon dioxide(CO_(2))conversion toward C1/C2 chemical ***,the lack of actual information on the vicinal Cu interfaces hinders the intrinsic activitystructure correlation *** with atomic-scale in situ characterizations(AP-STM and synchrotron-based AP-XPS),Park and co-workers study and identify the adsorbate-driven morphological evolution of Cu nanoclusters on the Cu(997)surface,providing real-space evidence for the critical role of vicinal structures on Cu *** observed surface roughening trends caused by dissociated atomic oxygen and CO adsorbates subsequently affect the result of successive catalytic reactions to produce critical intermediates,such as carbonate and formate,during the CO_(2)reduction reaction.

关键词： reaction critical rational

Heavy ion energy influence on multiple-cell upsets in small sensitive volumes:from standard to high energies

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Nuclear Science and Techniques 2024年第5期35卷 109-121页

作者： yang Jiao Li-Hua Mo Jin-Hu yang yu-Zhu Liu ya-nan Yin Liang Wang Qi-yu Chen Xiao-yu yan Shi-Wei Zhao Bo Li You-Mei Sun Pei-Xiong Zhao Jie Liu Institute of Modern Physics Chinese Academy of ScienceLanzhou 730000China University of Chinese Academy of Science Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China China Electronics Technology Group Corporation No.58 Research Institute Wuxi 214000China Beijing Microelectronics Technology Institute Beijing 100084China Institute of Microelectronics Chinese Academy of SciencesBeijing 100029China Key Laboratory of Science and Technology on Silicon Devices Chinese Academy of SciencesBeijing 100029China

The 28 nm process has a high cost-performance ratio and has gradually become the standard for the field of radiation-hardened ***,owing to the minimum physical gate length of only 35 nm,the physical area of a standard 6T SRAM unit is approximately 0.16μm^(2),resulting in a significant enhancement of multi-cell charge-sharing ***-cell upsets(MCUs)have become the primary physical mechanism behind single-event upsets(SEUs)in advanced nanometer node *** range of ionization track effects increases with higher ion energies,and spacecraft in orbit primarily experience SEUs caused by high-energy ***,ground accelerator experiments have mainly obtained low-energy ion irradiation ***,the impact of ion energy on the SEU cross section,charge collection mechanisms,and MCU patterns and quantities in advanced nanometer devices remains *** this study,based on the experimental platform of the Heavy Ion Research Facility in Lanzhou,low-and high-energy heavy-ion beams were used to study the SEUs of 28 nm SRAM *** influence of ion energy on the charge collection processes of small-sensitive-volume devices,MCU patterns,and upset cross sections was obtained,and the applicable range of the inverse cosine law was *** findings of this study are an important guide for the accurate evaluation of SEUs in advanced nanometer devices and for the development of radiation-hardening techniques.

关键词： 28 nm static random access memory(SRAM) Energy effects Heavy ion Multiple-cell upset(MCU) Charge collection Inverse cosine law