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World Journal of Gastroenterology 2007年第13期13卷 1980-1982页

作者： Ting-Chong Zhang Wen-Bo pang ya-Jun Chen Jin-Zhe Zhang Department of Surgery Beijing Children's Hospitalaffiliated to Capital Medical University Beijing 100045 China

AIM： TO explore the pathogenesis of the rectovestibular disruption （RVD） defect and to recommend a successful repair, and prevention of it. METHODS： Clinical records of 15 girls, age ranged from 3 to 15 （median, 7.5） years, with acquired rectovestibular fistula （RVF） mistreated before were retrospectively reviewed. All of them presented an abnormal appearance of perineum and were suffering from some degree of fecal incontinence, and those were graded Ⅲ to IV by Li Zheng＇s Score. Repair of anal sphincters and reconstruction of perineum body and skin by anterior perineal rectoanoplasty were performed in all cases. RESULTS： Operation in all cases was successful. The *** looked practically normal and fecal continence score rose up to VI by Li Zheng＇s Score. CONCLUSION： The conventional treatment for anal fistula, lay-open or string-treatment, should be considered as malpractice of RVF, and certainly leads to the RVD defect, and the anterior perineal rectoanoplasty could cure it satisfactorily.

关键词： Rectovestibular fistula Acquired Disruption Children

A critical review on the application of biochar in environmental pollution remediation:Role of persistent free radicals(PFRs)

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Journal of Environmental Sciences 2021年第10期33卷 201-216页

作者： Kun Luo ya pang Dongbo Wang Xue Li Liping Wang Min Lei Qi Huang Qi yang Department of Bioengineering and Environmental Science Changsha UniversityChangsha 410003China College of Environmental Science and Engineering Hunan UniversityChangsha 410082China

Biochar as an emerging carbonaceous material has exhibited a great potential in environmental application for its perfect adsorption ***,there are abundant persistent free radicals(PFRs)in biochar,so the direct and indirect PFRs-mediated removal of organic and inorganic contaminants by biochar was widely *** order to comprehend deeply the formation of PFRs in biochar and their interactions with contaminants,this paper reviews the formation mechanisms of PFRs in biochar and the PFRs-mediated environmental applications of biochar in recent ***,future challenges in this field are also *** review provides a more comprehensive understanding on the emerging applications of biochar from the viewpoint of the catalytic role of PFRs.

关键词： Biochar Organic and inorganic contaminants Persistent free radicals Degradation Reactive oxygen species

Comparison of microendoscopic discectomy and open discectomy for single-segment lumbar disc herniation

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World Journal of Clinical Cases 2020年第14期8卷 2942-2949页

作者： Jiu-ya pang Fei Tan Wei-Wei Chen Cui-Hua Li Shu-Ping Dou Jing-Ran Guo Li-Ying Zhao Department of Traumatology The Second Hospital of TangshanTangshan 0630000Hebei ProvinceChina Intensive Care Unit The Second Hospital of TangshanTangshan 0630000Hebei ProvinceChina Department of Nursing The Second Hospital of TangshanTangshan 0630000Hebei ProvinceChina Department of Hand Surgery The Second Hospital of TangshanTangshan 0630000Hebei ProvinceChina Department of Spinal Surgery The Second Hospital of TangshanTangshan 0630000Hebei ProvinceChina Hospital Office The Second Hospital of TangshanTangshan 0630000Hebei ProvinceChina

BACKGROUND Lumbar disc herniation is a common *** treatment may have more advantages than traditional *** To compare the clinical efficacy and safety of microendoscopic discectomy(MED)and open discectomy with lamina nucleus enucleation in the treatment of singlesegment lumbar intervertebral disc *** Ninety-six patients who were operated at our hospital were selected for this *** with single-segment lumbar disc herniation were admitted to the hospital from March 2018 to March 2019 and were randomly divided into the observation group and the control group with 48 cases in each *** former group underwent lumbar discectomy and the latter underwent laparotomy and nucleus *** effects were compared between the two *** In terms of surgical indicators,the observation group had a longer operation time,shorter postoperative bedtime and hospital stay,less intraoperative blood loss,and smaller incision length than the control group(P<0.05).The excellent recovery rate did not differ significantly between the observation group(93.75%)and the control group(91.67%).Visual analogue scale pain scores were significantly lower in the observation group than in the control group at 1 d,3 d,1 mo,and 6 mo after surgery(P<0.05).The incidence of complications was significantly lower in the observation group than in the control group(6.25%vs 22.92%,P<0.05).CONCLUSION Both MED and open discectomy can effectively improve single-segment lumbar disc herniation,but MED is associated with less trauma,less bleeding,and a lower incidence of complications.

关键词： Lumbar intervertebral discectomy open discectomy with fenestrated windows Single-segment lumbar disc herniation Nerve root Nucleus pulposus Pain

5-HT modulates the firing activity of subthalamic neurons by multiple receptor mechanisms in 6-OHDA parkinsonian rats

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5-HT modulates the firing activity of subthalamic neurons by...

The Effect of COVID-19 on the Cancer Patients Treated with Radiotherapy in Low Risk Area: A Single-Center Descriptive

中国生理学会第24届全国会员代表大会暨生理学学术大会

作者：王华 pang ya-yan CHEN Lei 青岛大学 Department of Physiology Binzhou Medical University Department of Physiology Faculty of MedicineQingdao University

Objective:The subthalamic nucleus（STN）plays a critical role in movement *** is well known that the firing rate and pattern of the subthalamic neurons is directly related to the manifestation of Parkinson’s disease.5-hydroxytrptamine（5-HT）has been reported to play an important role in the *** studies have indicated that the STN receives serotonergic innervation from the raphe nuclei and expresses several serotonergic receptor *** present study is to further investigate the in vivo modulation of firing activity by different 5-HT receptor subtypes in the STN of parkinsonian ***:In vivo extracellular recordings were performed in the present ***:（1）The basal firing rate of subthalamic neurons（11.07±0.85 Hz,n=84）in the lesioned side of parkinsonian rats was significantly faster（P＜0.001）than that of normal rats（7.80±0.54 Hz,n=138）.Furthermore,compared to that of normal rats,the overall distribution of discharge pattern in subthalamic neurons of parkinsonian rats changed significantly,with the increased number of bursty firing neurons（P＜0.001）and decreased number of regular firing neurons（P＜0.01）.（2）In parkinsonian rats,5-HT（0.1m M）increased the firing rate by 31.12±4.27%in 25 out of the 38 *** another 13 neurons,5-HT inhibited the firing rate by 23.10±7.05%.（3）To explore the receptor mechanism of 5-HT-induced excitatory and inhibitory effects on subthalamic neurons,5-HT1B receptor agonist（CP-93129）,5-HT2C receptor agonist（RO-600175）,5-HT4 receptor agonist（ML-10302）and 5-HT1A receptor agonist（8-OH-DPAT）were applied,***-pressure injection of CP-93129,RO-600175,and ML-10302,increased the spontaneous firing rate of subthalamic neurons in the lesioned side of parkinsonian rats,*** average increase was 25.11±3.79%,22.82±4.02%and 23.99±2.79%（P＜0.01,compared with saline control group）.However,the application of 8-OH-DPAT reduced the discharge frequency by 18.75±2.70%（P＜0.01）.Conclusio

关键词： 5-HT subthalamic nucleus extracellular recording Parkinson

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Journal of Cancer Therapy 2022年第5期13卷 275-283页

作者： Ping Zheng Junyi Cao Ke Liu ya pang Dong Wang Department of Oncology Zigong First People’s Hospital Zigong Sichuan Medical Record Room Zigong First People’s Hospital Zigong Sichuan

Objective: To investigate the influence of the new coronavirus epidemic on tumor radiotherapy patients in Zigong City, and provide radiotherapy feasibility and safety in other prefecture-level or low-risk areas. Methods: Retrospective Collection of data from January 31, 2020, in our hospital, this time period is an epidemic group. The control group was data from January 31, 2019-May 31, in our hospital. Patient data includes gender, age, tumor type, hospitalization fee, average hospitalization day, radiotherapy completion, treatment destination, and other information. Results: The patients with epidemic groups and control groups were 320 and 237, respectively, and the radiotherapy patients increased by 25.9%, increasing patients mainly from other departures outside the tumor department underperformance reform intervention. The epidemic group of brain and breast tumor patients were 39 and 37, respectively, with statistical differences (P 0.05). Inpatient costs, the average hospitalization day, radiotherapy completion, the purpose of treatment, and other data epidemic groups and control groups have no statistical difference (P > 0.05). Conclusion: The number of COVID-2019 epidemic interventions has increased the number of cancer radiotherapy patients in our hospital, and the epidemic situation has no effect on hospitalization, the average hospitalization day, radiotherapy, and the like. Optimizing the process of clinical treatment, strict prevention and control measures can ensure timely and safe radiotherapy in low-risk areas.

关键词： COVID-2019 Radiotherapy Prevention and Control Low-Risk Areas Single Center

Scopolamine causes delirium-like brain network dysfunction and reversible cognitive impairment without neuronal loss

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Zoological Research 2023年第4期44卷 712-724页

作者： Qing Wang Xiang Zhang Yu-Jie Guo ya-yan pang Jun-Jie Li yan-Li Zhao Jun-Fen Wei Bai-Ting Zhu Jing-Xiang Tang yang-yang Jiang Jie Meng Ji-Rong Yue Peng Lei Department of Geriatrics and State Key Laboratory of Biotherapy National Clinical Research Center for GeriatricsWest China HospitalSichuan UniversityChengduSichuan 610041China Pediatric Research Institute Ministry of Education Key Laboratory of Child Development and DisordersNational Clinical Research Center for Child Health and DisordersChongqing Key Laboratory of Translational Medical Research in Cognitive Development and Learning and Memory DisordersChildren's Hospital of Chongqing Medical UniversityChongqing 400014China

Delirium is a severe acute neuropsychiatric syndrome that commonly occurs in the elderly and is considered an independent risk factor for later ***,given its inherent complexity,few animal models of delirium have been established and the mechanism underlying the onset of delirium remains ***,we conducted a comparison of three mouse models of delirium induced by clinically relevant risk factors,including anesthesia with surgery(AS),systemic inflammation,and neurotransmission *** found that both bacterial lipopolysaccharide(LPS)and cholinergic receptor antagonist scopolamine(Scop)induction reduced neuronal activities in the delirium-related brain network,with the latter presenting a similar pattern of reduction as found in delirium ***,Scop injection resulted in reversible cognitive impairment with hyperactive *** loss of cholinergic neurons was found with treatment,but hippocampal synaptic functions were *** findings provide further clues regarding the mechanism underlying delirium onset and demonstrate the successful application of the Scop injection model in mimicking delirium-like phenotypes in mice.

关键词： Delirium Scopolamine Cholinergic neuron Neuronal activity Brain network

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职前与在职小学数学教师HCK的比较研究

数学教育学报 2018年第1期27卷 58-61页

作者：庞雅丽上海师范大学教育学院 Texas A&M University教育学院

从知识的起源、知识的横向联系、知识的纵向联系、知识的本质4个维度考查职前与在职小学数学教师的HCK（横纵向内容知识）这类学科知识的掌握情况.研究发现,被试的HCK不够丰富;不同教龄的教师的HCK水平无显著差异;修过小学数学知识理论... 详细信息

从知识的起源、知识的横向联系、知识的纵向联系、知识的本质4个维度考查职前与在职小学数学教师的HCK（横纵向内容知识）这类学科知识的掌握情况.研究发现,被试的HCK不够丰富;不同教龄的教师的HCK水平无显著差异;修过小学数学知识理论类课程的职前教师的HCK水平显著高于10年内教龄的在职教师.基于研究结果,对职前和在职小学数学教师教育提出一些建议.

关键词： MKT HCK 小学数学教师

Adsorption Behavior of Hexavalent Chromium in Vadose Zone

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Journal of Groundwater Science and Engineering 2013年第3期1卷 83-88页

作者： Cui-ling Wang Chang-li Liu ya-jie pang Li-xin Pei Yun Zhang Institute of Hydrogeology and Environmental Geology Center for Hydrogeology and environmental Geology Survey

Adsorption behavior of Cr(Ⅵ) in vadose zone, which is silty clay and clayey soil, was studied through kinetics experiments, isothermal adsorption experiments under various conditions, including different ph, temperature and organic contents. The results from kinetics experiments showed that the sorption progress of Cr(Ⅵ) has clear features in different stages, and adsorption equilibrium showed at 30 min, the adsorption rate of silty clay and clayey soil were 60%. The isothermal adsorption curve of Cr(Ⅵ) fitted closely with Freundlich equation model. When pH is 3-5 a plateau were seen, thereafter with increase in pH the adsorption rate of Cr(Ⅵ) dropped sharply and the minimum achieved at pH 10, the adsorption rate were only 35%. Adsorption rate of Cr(Ⅵ) increased gradually with the increase of temperature, the temperature of vadose zone is 14.7 ℃, according to the experimental results, the adsorption rate of Cr(Ⅵ) is about 40%. The use of organics represents an important contribution to the sorption of Cr(Ⅵ), sorption rate up to 100% when 30% of organic content. These studies will provide basis for manager to minimize the impacts, and provide basic data for pollution prevention and remediation of vadose zone.

关键词： Cr (VI) Adsorption Behavior Vadose zone

Treatment of 17 cases of anisometropic amblyopia in children with tuina at“Simingxue”combined with pressing therapy at auricular points

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World Journal of Acupuncture-Moxibustion 2021年第2期31卷 151-153页

作者： ya-zheng pang Kai WANG Meng-sen ZHANG Juan YU Acupuncture-Moxibustion and Tuina school of Shandong University of Traditional Chinese Medicine Ji'nan 250355China Department of Acupuncture-Moxibustion and Massage Shandong Third Provincial HospitalJi'nan 250031China Pediatric Tuina Center Affiliated Hospital of Shandong University of Traditional Chinese MedicineJi'nan 250015China

The article introduced the application of Tuina at"Simingxue"(four points named after"ming")and pressing therapy at auricular points in treatment of 17 cases of anisometropic amblyopia in *** methods:pressing and kneading with the thumb at Jingming(睛明BL1),Shangming(上明Extra),Yiming(翳明EX-HN14)and Guangming(光明GB37).Pressing with the finger digital at Yintang(印堂EX-HN3),Cuanzhu(攒竹BL2),Yuyao(鱼腰EX-HN4),Taiyang(太阳EX-HN5),Yingbai(阳白GB14),Sizhukong(丝竹空TE23),Tongziliao(瞳子髎GB1),Qiuhou(球后EX-HN7)and Chengqi(承泣ST1).Scraping the upper and lower orbits,nipping the eyebrows,pushing the orbits,pushing baoping and warming the *** Quchi(曲池LI11),Hegu(合谷LI4),GB37,Zusanli(足三里ST36),Xuehai(血海SP10)and Sanyinjiao(三阴交SP6).Rolling on the bilateral distributions of bladder meridian on the *** and kneading at Touwei(头维ST8),Qucha(曲差BL4),Baihui(百会GV20),Sishencong(四神聪EX-HN1),Fengchi(风池GB20)and Dazhui(大椎GV14).Grasping five meridians,scattering bilateral temporal regions,grasping and kneading the neck and nape region and holding Jianjing(肩井GB21).Auricular pressing therapy was exerted at yan(眼eye,LO5),Gan(肝liver,CO12),Shen(肾kidney,CO10),Pi(脾spleen,CO13),Wei(胃stomach,CO4),Pizhixia(皮质下subcortex,AT4),Pingjianqian(屏间前anterior intertragic notch,TG21)and Pingjianhou屏间后(posterior intertragic notch,AT11).The treatment was given 3 times a week,6 treatments made one course and 4 courses of treatment were *** 17 patients,2 cases were cured,13 cases cured basically,1 case improved and 1 case *** total effective rate was 88.2%.

关键词： Amblyopia Auricular point pressing therapy Pediatric Tuina

Case of stenosing tenosynovitis of the thumb in children

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World Journal of Acupuncture-Moxibustion 2021年第3期31卷 233-235页

作者： ya-zheng pang Kai WANG Meng-sen ZHANG Juan YU School of Acupuncture-Moxibustion and Massage Shandong University of Traditional Chinese MedicineJinan 250355China Department of Acupuncture-Moxibustion and Massage Shandong Provincial Third HospitalJinan 250031China Pediatric Tuina Health Care Clinic Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinan 250014China

A female patient,13 months old,suffering from limited extension of the right thumb for 7 days,diagnosed as stenosing tenosynovitis of the thumb in ***(Chinese massage) therapy was adopted,in which,stimulation was applied with fingers instead of needles,including pressing and kneading,twisting and kneading,plucking,dorsal extending,rotating as well as pushing and rubbing *** whole procedure of manipulation lasted around 15 min,once every two days,3 times ***,the parents were advised to bath the child patient's right hand into warm water every day and fix the affected thumb with splint at *** 12 treatments with tuina therapy,the flexion and extension function of the affected thumb were returned to normal and the thumb motor function was *** 2 months of follow-up,the thumb motor function was normal and the stenosing tenosynovitis was not *** this case,tuina therapy is adopted in treatment of stenosing tenosynovitis of the thumb in *** an alternative method of surgery,tuina therapy has a satisfactory clinical effect.

关键词： Stenosing tenosynovitis of the thumb Pediatric tuina Tuina Massage Pressing and kneading Twisting and kneading Plucking