检索结果-南通市图书馆

Patellar dislocation following distal femoral replacement after extraarticular knee resection for bone sarcoma:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第11期10卷 3561-3572页

作者： yuta kubota Kazuhiro Tanaka Masashi Hirakawa Tatsuya Iwasaki Masanori Kawano Ichiro Itonaga Hiroshi Tsumura Orthopaedic Surgery Oita UniversityYufu City 879-5593OitaJapan

BACKGROUND For the treatment of bone sarcoma in the distal femur,wide-margin resection and knee reconstruction with tumor endoprosthesis are standard *** knee resection is required in cases of tumor invasion of the knee joint;however,the incidence of complications,such as aseptic loosening,prosthesis infection,and implant failure,is higher than that following intra-articular knee *** the best of our knowledge,there are three reports of patellar dislocations after replacement of a tumor *** SUMMARY A 36-year-old man with no significant past medical history was admitted to our institution with continuous pain in his left knee for 4 *** open biopsy was performed,and the patient was diagnosed with a left distal femoral malignant bone ***-articular knee resection and knee reconstruction with a tumor endoprosthesis were *** the alignment of the tumor prosthesis was acceptable,knee instability was noticed *** axial radiographic view of the patellar and computed tomography showed lateral patellar dislocation at 4 wk *** patient had to undergo a lateral release and proximal *** could perform his daily activities at 9 mo *** revealed no patellar *** Proximal realignment may be considered during primary surgery if there is an imbalance in the forces controlling the patellar tracking.

关键词： Bone tumor Distal femoral replacement Lateral release Patellar dislocation Proximal realignment Case report

MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Research 2024年第3期32卷 463-476页

作者： Hur SUN MASANORI KAWANO TATSUYA IWASAKI ICHRO ITONAGA yuta kubota HROSHI TSUMURA KAZUHRO TANAKA Department of Orthopaedic Surgery Faculty of MedicineOita UniversityOita879-5503Japan

An important factor in the emergence and progre sion of osteosarcoma(OS)is the dysregulated expression of microRNAs(miRNAs).Transcription factor 7-like 1(TCF7LI),a member of the T cell factor/lymphoid enhancer factor(TCF/LEF)transcription factor family,interacts with the Wnt signaling pathway regulator β-catenin and acts as a DNA-specific binding *** study sought to elucidate the impact of the interaction between miR 3293p and TCF7L1 *** growth and apoptosis of OS and analyze the regulatory expression relationship between miRNA and mRNA in osteosarcoma cells using a variety of ***329-3p was significantly downregulated,while TCF7L1 was considerably up-regulated in all examined OS cell ***,a clinical comparison study was performed using the TCGA ***,the regulatory relationship between miR-329-3p and TCF7L1 on the proliferation and apoptosis of OS cells was verified through in vitro and in vivo *** miR 329-3p was transfected into the OS cell line,the expression of TCF7L1 decreased,the proliferation of OS cells was inhibited,the cytoskeleton disintegrated,and the nucleus condensed to fom apoptotic *** expression of proteins that indicate apoptosis increased *** cell cycle was arrested in the G0/G1 phase,and the G1/S transition was *** introduction of miR 3293p also inhibited downstream Cyclin D1 of the Wnt *** experiments indicated that the overexpression of miR-329-3p signi ficanly inhibited the growth of OS xenografts in nude mice,and the expression of TCF7L1 and C-Myc in tumor tssues *** 329-3p was significantly reduced in OS cells and played a suppressive role in tumorigenesis and proliferation by targeting TCF7L1 both in vitro and in *** cell cycle arrest and pathway inhibition were observed upon the regulation of TCF7LI by miR *** these results,it can be inferred that miR.3293p exerts anticancer efects in osteosarcom

关键词： MiR-329-3p TCF7L1 Wnt/β-catenin pathway Osteosarcoma Proliferation

Correction: MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Research 2024年第8期32卷 1369-1370页

作者： HUI SUN MASANORI KAWANO TATSUYA IWASAKI ICHIRO ITONAGA yuta kubota HIROSHI TSUMURA KAZUHIRO TANAKA Department of Orthopaedic Surgery Faculty of MedicineOita UniversityOita879-5503Japan

In the article‘MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1’(Oncology Research,2024,Vol.32,No.3,pp.463−***:10.32604/or.2023.044085),there was an error in the compilation of *** have revised Fig.8D to correct this error.A corrected version of Fig.8 is *** correction does not change any results or conclusions of the *** apologize for any inconvenience caused.

关键词： osteosarcoma correction revised

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2021年第5期21卷 43-70页

作者： yuta Ito Department of Physics The Graduate Center of CUNY365 Fifth AvenueNew YorkNY 10016USA Department of Physics and Astronomy The College of Staten Island of CUNY2800 Victory BoulevardStaten IslandNY 10314USA

Fitting parametric models to globular clusters’structural profiles has been essential for the study of stellar *** provides their important structural parameters,such as the concentrations and core radii of the ***,existing parametric models can apply only to non-collapsing-core clusters in the early relaxation-evolution ***,a single parametric model cannot provide globular clusters’structural parameters in both the early and late evolution *** have recently found an accurate spectral solution for the self-similar orbit-averaged Fokker-Planck(OAFP)equation to model collapsingcore clusters at the late evolution *** present work establishes a new parametric model by combining the self-similar OAFP-and *** it is a single-mass and isotropic model,the new model applies to at least fifty-five Galactic globular clusters with resolved cores in all the evolution *** a main result,we show the characteristics of the relaxation times against the concentrations of the *** also affirm that the structures of low-concentration clusters are polytropic in the Milky Way.

关键词： (Galaxy:)globular clusters:general Galaxy:kinematics and dynamics methods:numerical

Drag-reduction behavior of an unusual nonionic surfactant in a circular pipe turbulent flow

在线全文

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 2014年第3期26卷 400-405页

作者：蔡书鹏 HIGUCHI yuta Institute of High Pressure Water Jet Hunan University of Technology Graduate School of Science and Technology Kobe University

The Alkyl Polyglucoside（APG） is a nonionic surfactant with no toxicity and with high biodegradability, its drag-reduction behavior in a circular pipe flow is measured, and the rheological characteristics are investigated with a rheometer with a cone-plate flow cell. From the measured results, the APG is shown to have a high drag-reduction capacity, whose shear viscosity is shear-ratedependent at high concentrations, while its solution at concentrations with drag-reduction effects is non-viscoelastic as verified by zero relaxation time in the relaxation process of the shear stress, which contradicts the general viewpoint that there is a correlation between the viscoselastic characteristics and the turbulent drag reduction for the drag-reduction surfactant. However, the APG solution is birefringent as observed through a birefringent test, which indicates that there are rod-shaped micelles in the solution under the shearing flow. The higher extensional viscosity inferred from the extensional phenomenon observed in the measurements of the shear viscosity could be responsible for the drag reduction property of this nonionic surfactant.

关键词： drag reduction shear stress relaxation relaxation time viscoelasticity

Lepton mass matrix from double covering of A_(4) modular flavor symmetry

在线全文

学校读者我要写书评

暂无评论

Chinese Physics C 2022年第12期46卷 162-171页

作者： Hiroshi Okada yuta Orikasa Asia Pacific Center for Theoretical Physics(APCTP)-Headquarters San 31 Hyoja-dongNam-guPohang 790-784Korea Department of Physics Pohang University of Science and TechnologyPohang 37673Republic of Korea Institute of Experimental and Applied Physics Czech Technical University in PragueHusova 240/511000 Prague 1Czech Republic

We study a double covering of modular A_(4)flavor *** this end,we construct lepton models for canonical and radiative seesaw *** irreducible doublet representations,heavier Majorana fermion masses are characterized by one free parameter that would differentiate from A_(4)***χsquare numerical analysis,we demonstrate that both scenarios produce some predictions in case of normal hierarchy reproducing neutrino oscillation ***,no solution satisfies the neutrino oscillation data in case of radiative seesaw of inverted hierarchy.

关键词： flavor physics neutrino and Lepton mass beyond the standard model

MicroRNA-based targeting of the Rho/ROCK pathway in therapeutic strategies after spinal cord injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第2期18卷 311-312页

作者： Tetsu Kimura yuta Horikoshi Department of Anesthesia and Intensive Care Medicine Akita University Graduate School of MedicineAkitaJapan

Spinal cord injury(SCI)is one of the leading causes of disability and is a devastating condition that requires long-term care,reduces social productivity,and gives an immense emotional burden on patients and their fa *** frequently occurs due to traffic accidents,falls,slips,violence,sports,and medical accidents in today's *** initial mechanical damage triggers a secondary injury cascade that induces more intractable damage(Silva et al.,2014).Secondary injury mechanisms have been postulated,including neuronal apoptosis,inflammation,oxidative stress,and excitotoxicity.

关键词： damage injury emotional

Is the magic texture of Majorana neutrinos immanent in Dirac nature?

在线全文

学校读者我要写书评

暂无评论

Chinese Physics C 2023年第4期47卷 66-73页

作者： yuta Hyodo Teruyuki Kitabayashi Graduate School of Science and Technology Tokai University4-1-1 KitakanameHiratsukaKanagawa 259-1292Japan Department of Physics Tokai University4-1-1 KitakanameHiratsukaKanagawa 259-1292Japan

Magic textures are successful candidates of the correct texture for Majorana *** this study,we demonstrate that several types of magic textures of Majorana neutrinos are approximately immanent in the flavor mass matrix of Dirac *** addition,the normal mass ordering of Dirac neutrino masses is slightly preferable to inverted mass ordering in the context of magic textures.

关键词： neutrino mixing mass matrix magic texture

Counter-Rotating Type Tidal Stream Power Unit Boarded on Pillar(Performances and Flow Conditions of Tandem Propellers)

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2013年第6期22卷 580-585页

作者： yuta Usui Toshiaki Kanemoto Koju Hiraki Kyushu Institute of Technology: Sensui 1-1 TobataKitakyushuFukuoka804-8550Japan

The authors have invented the unique counter-rotating type tidal stream power unit composed of the tandem pro- peUers and the double rotational armature type peculiar generator without the traditional stator. The front and the rear propellers counter-drive the inner and the outer armatures of the peculiar generator, respectively. The unit has the fixftful advantages that not only the output is sufficiently higher without supplementary equipment such as a gearbox, but also the rotational moment hardly act on the pillar because the rotational torque of both propel- lers/armatures are counter-balanced in the unit. This paper discusses experimentally the performances of the power unit and the effects of the propeller rotation on the sea surface. The axial force acting on the pillar in- creases naturally with the increase of not only the stream velocity but also the drag of the tandem propellers. Be- sides, the force vertical to the stream also acts on the pillar, which is induced from the Karman vortex street and the dominant frequencies appear owing to the front and the rear propeller rotations. The propeller rotating in close to the sea surface brings the abnormal wave and the amplitude increases as the stream velocity is faster and/or the drag is stronger.

关键词： Tidal stream Counter rotation Tandem propellers Generator Armature