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面向界面交互的色彩体系辅助设计技术研究

包装工程 2024年第18期45卷 264-274,329页

作者：曹愉静金永承中移(杭州)信息技术有限公司杭州311100

目的探索界面设计中的色彩体系搭建技术,辅助设计师进行人机交互设计,提升工作效率。方法分析当前互联网产品界面设计中色彩体系的应用场景及其搭建理论和方法。利用Web技术,开发一款快速生成批量色彩以辅助建立色彩体系的工具。工作流... 详细信息

目的探索界面设计中的色彩体系搭建技术,辅助设计师进行人机交互设计,提升工作效率。方法分析当前互联网产品界面设计中色彩体系的应用场景及其搭建理论和方法。利用Web技术,开发一款快速生成批量色彩以辅助建立色彩体系的工具。工作流程为程序获取到用户的目标主色色值以及预生成的色彩数量,基于HSB色彩模型,生成一定数量辅助色并利用灰度公式自动矫正色彩参数以达到视觉刺激同频,在得到矫正后的辅助色后,通过自动计算色相、饱和度、明度来生成每一个辅助色的序列色板。此外提供用户手动调整自动生成的辅助色的功能,得到的色彩规范可以随着工具的插件版安装至UI设计软件Sketch中,供设计师进行配色工作。结论工具的推出为视觉设计师的色彩体系搭建提供了快速处理能力,其高效性、科学性和便于传播性极大地提高了界面配色的美观性和统一性,有利于构建良好的用户体验,对产品研发团队具有一定的增值意义。

关键词：界面设计色彩体系用户体验 HSB色彩模型无障碍设计配色设计

维普期刊数据库博看期刊

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突发事件协同研判行为的演化博弈分析

清华大学学报（自然科学版） 2024年第5期64卷 900-910页

作者：袁晓芳于鸿志曹玉静王新平西安科技大学管理学院西安710054 西安科技大学人因与管理工效学研究中心西安710054

突发事件协同研判中多个主体决策立足的收益路径不同,易导致突发事件研判失效、风险事件损失扩大,是目前亟待解决的关键性问题。该文以前景理论-心理账户(PT-MA)为基础,应用演化博弈模型研究了突发事件协同研判的参与主体(公众、一线人... 详细信息

突发事件协同研判中多个主体决策立足的收益路径不同,易导致突发事件研判失效、风险事件损失扩大,是目前亟待解决的关键性问题。该文以前景理论-心理账户(PT-MA)为基础,应用演化博弈模型研究了突发事件协同研判的参与主体(公众、一线人员、应急指挥部)之间复杂行为的互动机制,分析了各博弈主体策略选择的稳定性,并对关键参数变化下的行为演化路径进行仿真分析。模型分析结果表明:三方主体的协同研判策略选择存在3个平衡点;当应急指挥部的感知收益提高且处罚力度加大时,系统将达到最优。仿真分析结果表明:通过调整初始概率、收获感知参照点和惩罚力度3个参数,主体策略趋于正向,且收敛速度随着参数的增加而显著提升。因此可以通过加大奖励措施,提升决策初始概率值;通过表彰先进个人和组织公益宣讲等,降低收益感知参考点;通过完善相关惩罚条例并增加监督举报措施,提高消极策略的惩罚力度。以此促进协同研判主体的策略选择向积极方向演化。

关键词：突发事件协同研判前景理论心理账户演化博弈

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国内外铁路绿色发展现状及内涵研究

铁路节能环保与安全卫生 2024年第4期14卷 34-40页

作者：甄凯曹宇静曹孙喆中国铁道科学研究院集团有限公司节能环保劳卫研究所北京100081

铁路具有绿色低碳环保优势,在推动绿色发展、促进人与自然和谐共生中做出积极贡献。在提出绿色铁路内涵的基础上,系统梳理了国内外铁路绿色发展现状,总结了德国、法国、日本、美国等典型发达国家铁路绿色发展经验与启示,从设计、施工建... 详细信息

铁路具有绿色低碳环保优势,在推动绿色发展、促进人与自然和谐共生中做出积极贡献。在提出绿色铁路内涵的基础上,系统梳理了国内外铁路绿色发展现状,总结了德国、法国、日本、美国等典型发达国家铁路绿色发展经验与启示,从设计、施工建造、装备、运营管理等方面调研了我国铁路绿色技术发展现状,提出未来我国绿色铁路发展方向,为助力节能减排和“双碳”目标实现提供理论支撑。

关键词：绿色铁路发展现状内涵

术前及术后膜性尿道长度与腹腔镜根治性切除术后尿控功能的相关性

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国际泌尿系统杂志 2024年第3期44卷 498-502页

作者：郭洪玉石蕊曹宇京首都医科大学附属北京友谊医院泌尿外科北京100050

目的:探讨腹腔镜前列腺根治性切除术(LRP)患者术前和术后的膜性尿道长度(MUL)及前列腺体积与尿控功能恢复之间的相关性。方法:回顾性分析2019年6月至2021年12月期间在本院接受LRP治疗的110例前列腺癌患者的临床资料。采用3.0T西门子磁... 详细信息

目的:探讨腹腔镜前列腺根治性切除术(LRP)患者术前和术后的膜性尿道长度(MUL)及前列腺体积与尿控功能恢复之间的相关性。方法:回顾性分析2019年6月至2021年12月期间在本院接受LRP治疗的110例前列腺癌患者的临床资料。采用3.0T西门子磁共振仪测量患者的MUL和前列腺体积,评估患者术后1、3、6及12个月的尿控情况。收集并分析患者的基本信息、术前临床指标和术中相关因素,包括年龄、体质量指数(BMI)、前列腺特异性抗原(PSA)水平、Gleason评分、病理分期等。采用logistic回归分析患者术后尿控功能恢复的影响因素。结果:术后1个月时,19.09%(21/110)的患者恢复了尿控功能,术后3个月时增至47.27%(52/110),6个月时为65.45%(72/110),12个月时达到91.82%(101/110)。logistic回归分析结果显示,MUL≥14 mm、膀胱颈保留、后方颈膜重建和前列腺体积均是患者术后尿控功能恢复的独立影响因素(均P50 mL)的患者在尿控功能恢复方面表现较差。结论:在LRP术后,患者尿控功能的恢复受MUL和前列腺体积的显著影响。MUL越长,其尿控制能力越好,而越大的前列腺体积则越不能改善其尿控功能的恢复。

关键词：前列腺肿瘤前列腺切除术腹腔镜检查尿道控尿功能

带阔筋膜的游离股前外侧皮瓣分叶组合修复前臂不规则创面

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中华手外科杂志 2024年第3期40卷 198-201页

作者：宋鹏李强石霞曹玉净刘辉刘一正 I河南省中医院(河南中医药大学第二附属医院)创伤外科郑州450053 ²河南中医药大学骨伤学院教学与生物力学实验室郑州450046

目的探讨带阔筋膜的游离股前外侧皮瓣分叶组合修复前臂不规则创面的临床疗效.方法自2017年7月至2022年7月,我院收治前臂不规则创面患者9例,其中6例伴有血管神经损伤,所有创面一期行清创、负压封闭引流,术后均合并不同程度的肌腱、骨质外... 详细信息

目的探讨带阔筋膜的游离股前外侧皮瓣分叶组合修复前臂不规则创面的临床疗效.方法自2017年7月至2022年7月,我院收治前臂不规则创面患者9例,其中6例伴有血管神经损伤,所有创面一期行清创、负压封闭引流,术后均合并不同程度的肌腱、骨质外露,创面大小8.5 cm×10.0cm~7.0 cm×17.0 cm,二期应用带阔筋膜的游离股前外侧皮瓣分叶组合修复.先将前臂不规则大创面划分为2~3个小创面,用布片分别取样,然后将各个布样重新组成一个较规则形状来设计带阔筋膜的游离股前外侧皮瓣,皮瓣面积约8.0 cm×16.0 cm~8.0cm×18.0 cm,皮瓣切取后依据设计再分叶为2~3个皮瓣,皮瓣间保留部分阔筋膜相连,重新组合成前臂不规则形状修复创面.皮瓣术前彩超或便携式多普勒探查仪探查前臂尺、桡动脉和旋股外侧动脉穿支血管情况.皮瓣与尺侧血管分支吻合2例、端侧吻合1例、桥接吻合1例,皮瓣与桡侧血管分支吻合1例、端侧吻合2例、桥接吻合2例.供区创面均直接闭合.结果术中皮瓣分叶组合后血运张力适中,阔筋膜无明显扭转,术后皮瓣血运良好.创面和手术切口均Ⅰ期愈合.术后随访时间为6~15个月,平均(9.89±1.09)个月.皮瓣外观满意,未见明显臃肿,质地柔软,无色素沉着.供区仅余留线性瘢痕.结论带阔筋膜的游离股前外侧皮瓣切取方便,皮瓣分叶简单方便,组合后可以较好地修复前臂不规则创面,术后皮瓣外观质地均获得较满意结果.

关键词：前臂损伤外科皮瓣分叶不规则创面

Expression, distribution and function of the focal adhesion kinase (pp125^(FAK)) during murine ectoplacental cone outgrowth in vitro

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Chinese Science Bulletin 1998年第17期43卷 1473-1480页

作者： ZHANG Chunyu DUAN Enkui cao yujing ZENG Guoqing State Key Laboratory of Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100080China Boyer Center for Molecular Medicine Department of GeneticsYale University School of MedicineNew HavenCT 06510USA

Mouse embryo implantation is a complex process that includes trophoblast cells derived from ectoplacental cone (EPC) adhesion to and migration through the extracellular matrix (ECM) of uterine endometrium and invasion into the decidua. At the time of implantation, fibronectin (FN) is abundant in the decidua and is distributed pericellularly around each individual stromal cell, and its receptor (integrin α-5β-1) expression on trophoblast populations is up-regulated. The focal adhesion kinase, a 125 ku protein tyrosine kinase (pp125 FAK), is tyrosine phosphorylated upon integrin engagement with its ECM ligand, and its tyrosine phosphorylation sites then serve as the binding sites which couple it with cellular proteins that contain Src SH2 or SH3 domains. Through these linkages, pp125 FAK may integrate multiple signals triggered by integrins. The model of EPC culture %in vitro% was used to study the expression, distribution and function of pp125 FAK during EPC outgrowth on FN. Results indicated that, pp125 FAK primarily expressed and distributed in cellular focal adhesions of the front edge of trophoblast outgrowth from EPC, and was localized in the peripheral region of the individual migrating trophblast cell; antibody or antisense oligodeoxynucleotide to pp125 FAK inhibited EPC attachment and outgrowth, as well as trophoblast cells spreading and migration. This experiment demonstrated that pp125 FAK as an integrin-mediated signaling molecule was involved in EPC outgrowth %in vitro%, and played an important role during trophoblast cells interaction with FN.

关键词： fibronectin integrin focal adhesion kinase(pp125 FAK) ectoplacental cone attachment outgrowth.

Induction of matrix metalloproteinase-9 and-2 activity in mouse blastocyst by fibronectin-integrin interaction

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Chinese Science Bulletin 2000年第14期45卷 1266-1270页

作者： TIE Guodong cao yujing ZHAO Xingxu Duan Enkui State Key Laboratory of Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100080.China Department of Veterinary Medicine Gansu Agricultural UniversityLanzhou 730070China

Fibronectin, a major extracellular matrix, plays an important role in embryo implantation by mediating embryo adhesion and outgrowth. In this work, mouse blastocysts produced pro-matrix metalloproteinase-9, pro-matrix metalloproteinase-2 and 64 ku matrix metalloproteinase-2 when they were co-cultured with fibronectin. In contrast, mouse blastocysts did not produce these proteinases without fibronectin. Focal adhesion kinase is a fundamental molecule of integrin signaling pathway and its antisense oligodeoxynucleiotide inhibited blastocyst matrix metalloproteinases expression induced by fibronectin. The results indicated that fibronectin triggered matrix metalloproteinase-9 and -2 expression in mouse blastocyst through its integrin receptors and subsequent signaling pathway, which enhanced the synchronization of blastocyst invasiveness and uterine receptivity and ensured the accuracy of events relative to implantation in timing and spatiality.

关键词： fibronectin focal adhesion kinase (ppl2SFAK) blastocyst matrix metalloproteinase-9 matrix metalloprotein-ase-2.

Effect of fibronectin and leukaemia inhibitory factor on matrix metalloproteinases in mouse blastocyst

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Chinese Science Bulletin 2001年第15期46卷 1296-1300页

作者： Jian Zhang Guodong Tie yujing cao Enkui Duan Chinese Acad Sci Inst Zool State Key Lab Reprod Biol Beijing 100080 Peoples R China

This study was designed to detect the effects of fibronectin (FN) and leukaemia inhibitory factor (LIF) on matrix metallopoteinases (MMPs) of mouse blastocysts. The experiments comprised four groups: first, blastocysts grew on the dishes with FN-coated; the second, without FN-coated; the third group, without FN coated, but with 20 ng/μL LIF added to culture medium; and the fourth group, with both FN-coated and 20 ng/μL LIF added. Using MMP-2 and MMP-9 primers respectively, the expressions of MMP-2 and MMP-9 were detected by RT-PCR and cloning identification. The results showed that in the first group, MMP-2 and MMP-9 were produced after 12 and 24 h culturing; in the third group, there were both MMP-2 and MMP-9 bands when blastocysts were cultured for 24 h; and in the fourth group, MMP-2 and MMP-9 bands appeared when blastocysts were cultured for 6, 12 and 24 h. But in the second group no MMP-2 or MMP-9 band appeared. These results show that FN may initiate the transcription of MMP-2 and MMP-9 genes

关键词： matrix metalloproteinases fibronectin leukaemia inhibitory factor reverse transcription polymerase chain reaction mouse blastocyst.

Role of αVβ3 integrin in embryo implantation in the mouse

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Chinese Science Bulletin 2000年第22期45卷 2077-2081,2113页

作者： Liquan Cai yujing cao Enkui Duan State Key Laboratory of Reproductive Biology Institute of Zoology Chinese Acedemy of Sciences Beijing China

Integrin, a heterodimeric adhesive molecule composed of a and (5 subunits, can regulate cell adhesion and trafficking. Recent data have documented that, at the 'implantation window' stage, aVp3 integrin participates in the maternal-fetal interaction and becomes a potential marker of uterine receptivity. Furthermore, it can affect invasiveness of embryo. This work made a further study about its action mechanism. Results of indirect immunofluorescence and laser scanning confocal microscopy showed that αVβ3 integrin was clearly expressed in the mouse blastocyst. Injection of αVβS integrin antiserum into a uterine horn of a pregnant mouse on day 3 markedly decreased the number of embryos implanted (P < 0.001). In a co-culture model, aVp3 integrin antisera at 1 : 100 and 1 : 200 dilutions significantly depressed the attachment and outgrowth reactions of blastocysts on monolayer of uterine epithelial cells. Analysis of correlation manifested that the inhibitory effect of αVβ3 integrin antiserum was

关键词： αVβ3 integrin co-culture embryo implantation mouse.