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Chinese Journal of Electronics 2015年第2期24卷 361-365页

作者： MAO Chenglin WAN Shouhong yue Lihua xia Yu School of Computer Science and Technology University of Science and Technology of China

A novel model for segmentation of water/land in Synthetic aperture radar(SAR) images is presented. The proposed model calculates the global matrix of oriented gradient of histograms on wavelet subbands based on the multi-scale property, shift invariance and directional selectivity of Complex wavelet transform(CWT), then acquires edge information by thresholding the matrix. It improves the traditional Chan-vese(CV) model by adding the constraint of extracted edge information. A new water/land segmentation algorithm is then proposed based on the new model. The performance of proposed method is compared with some other existing algorithms and the experimental results confirm its effectiveness.

关键词： Water/land segmentation Complex wavelet transform Multi-scale Orientation selectivity Edge information Chan-vese model

Advance in the understanding of vasovagal syncope in children and adolescents

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World Journal of Pediatrics 2021年第1期17卷 58-62页

作者： Hong-xia Li Lu Gao yue Yuan Department of Cardiology National Center for Children's HealthBeijing Children's HospitalCapital Medical UniversityBeijingChina

Background Vasovagal syncope(VVS)accounts for 60-80% of cases of neurally mediated *** results from acute orthostatic intolerance and recurrent syncopal attacks,which can seriously affect an individual's quality of *** addition,some children even experience trauma during ***,it is particularly important to clarify the pathogenesis of *** aim of our study is to reveal the latest research progress of *** sources Literature that involved the pathogenesis of VVS were selected from Cochrane Library(1990-2019),EMBASE(1991-2019)and PubMed(1968-2019)*** Hypovolemia,autonomic dysfunction,vasomotor dysfunction,baroreceptor reflex abnormalities,endothelial dys-function,serotonin surges,and gut microbiota were involved in the underlying mechanism of *** VVS is not always a benign *** aspects were involved in its ***-Jarish reflex,dysfunction of the autonomic nervous system,genetic factors and so on played important roles in VVS;however,the mecha-nism remains unclear.

关键词： Autonomic nervous system Bezold-Jarish reflex Children Genetic pathogenesis Vasovagal syncope

Three-dimensional flexible Au nanoparticles-decorated TiO_(2) nanotube arrays for photoelectrochemical biosensing

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Journal of Materials Science & Technology 2020年第21期56卷 162-169页

作者： Xidong Zhang dong yue Ling Zhang Shiwei Lin State Key Laboratory of Marine Resource Utilization in South China Sea School of Materials Science and EngineeringHainan UniversityHaikou 570228China

Controlling the charge transfer and thus enhancing the excitons’lifetime are the key to the realization of efficient photoelectrochemical(PEC)***,fabrication of flexible and collapsible sensors can greatly facilitate the implementation of smart PEC sensing devices into practical ***,we sagely designed and successfully fabricated three-dimensional flexible Au nanoparticles-decorated TiO_(2) nanotube arrays(Au@TiO2)for the efficient PEC biosensing of *** Schottky barrier derived from the Au@TiO2 heterostructure efficiently separates the charge carriers at the junction interfaces,thus greatly increasing the concentration and lifetime of holes left in the valence band of *** separated holes further evidently generate the active hydroxyl radicals,which can specifically recognize and oxidize *** a result,Au@TiO_(2) exhibits excellent photoelectric activity and selectivity,far superior to TiO_(2) without decorated Au *** addition,such asymmetric Au@TiO_(2) system has been proved to feature the intrinsic flexibility nature,since its PEC biosensing performance is almost unaffected under indirect light irradiation and serious tensile strain.

关键词： Photoelectrochemical biosensing Metal/semiconductor interface Flexibility TiO_(2)nanotube arrays

Expression profiles of long noncoding RNAs in retinopathy of prematurity

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Neural Regeneration Research 2020年第10期15卷 1962-1968页

作者： yue Wang Xue Wang Yuan Ma yue-xia Wang Yu Di Department of Ophthalmology Shengjing Hospital of China Medical University

Long noncoding RNA(lncRNA)regulates the proliferation and migration of human retinal endothelial cells,as well as retinal neovascularization in diabetic *** on similarities between the pathogenesis of retinopathy of prematurity(ROP)and diabetic retinopathy,lncRNA may also play a role in ***-day-old mice were administered 75±2% oxygen for 5 days and normoxic air for another 5 days to establish a ROP *** of lncRNA and mRNA in the retinal tissue of mice was detected by high-throughput sequencing technology,and biological functions of the resulted differentially expressed RNAs were evaluated by Gene Ontology and Kyoto Encyclopedia of Genes and Genomes *** results showed that compared with the control group,57 lncRNAs were differentially expressed,including 43 upregulated and 14 downregulated,in the retinal tissue of ROP *** with control mice,42 mRNAs were differentially expressed in the retinal tissue of ROP mice,including 24 upregulated and 18 downregulated *** expressed genes were involved in ocular development and related metabolic *** differentially expressed lncRNAs may regulate ROP in mice via microRNAs and multiple signaling *** results revealed that these differentially expressed lncRNAs may be therapeutic targets for ROP *** study was approved by the Medical Ethics Committee of Shengjing Hospital of China Medical University on February 25,2016(approval No.2016PS074K).

关键词： bioinformatics gene therapy long noncoding RNA microglial neurovascular disease optic neuropathy retinal development retinal neovascularization retinopathy of prematurity signaling pathways

Physics-informed neural network-based petroleum reservoir simulation with sparse data using domain decomposition

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Petroleum Science 2023年第6期20卷 3450-3460页

作者： Jiang-xia Han Liang Xue Yun-Sheng Wei Ya-dong Qi Jun-Lei Wang yue-Tian Liu Yu-Qi Zhang National Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing102249China Department of Oil-Gas Field Development Engineering College of Petroleum EngineeringChina University of PetroleumBeijing102249China PetroChina Research Institute of Petroleum Exploration&Development Beijing100083China Lushang Oilfield Operation Area Jidong Oilfield CompanyPetroChinaTangshan063000HebeiChina

Recent advances in deep learning have expanded new possibilities for fluid flow simulation in petroleum ***,the predominant approach in existing research is to train neural networks using high-fidelity numerical simulation *** presents a significant challenge because the sole source of authentic wellbore production data for training is *** response to this challenge,this work introduces a novel architecture called physics-informed neural network based on domain decomposition(PINN-DD),aiming to effectively utilize the sparse production data of wells for reservoir simulation with large-scale *** harness the capabilities of physics-informed neural networks(PINNs)in handling small-scale spatial-temporal domain while addressing the challenges of large-scale systems with sparse labeled data,the computational domain is divided into two distinct sub-domains:the well-containing and the well-free ***,the two sub-domains and the interface are rigorously constrained by the governing equations,data matching,and boundary *** accuracy of the proposed method is evaluated on two problems,and its performance is compared against state-of-the-art PINNs through numerical analysis as a *** results demonstrate the superiority of PINN-DD in handling large-scale reservoir simulation with limited data and show its potential to outperform conventional PINNs in such scenarios.

关键词： Physical-informed neural networks Fluid flow simulation Sparse data Domain decomposition

Insights into the cross-amyloid aggregation of Aβ_(40) and its N-terminal truncated peptide Aβ_(11-40) affected by epigallocatechin gallate

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Chinese Journal of Chemical Engineering 2022年第5期35卷 284-293页

作者： yue Liang Wenjuan Wang Yan Sun xiaoyan dong Department of Biochemical Engineering and Key Laboratory of Systems Bioengineering(Ministry of Education) School of Chemical Engineering and TechnologyTianjin UniversityTianjin 300354China

Inhibition of protein misfolding and aggregation is a great challenge in the field of biochemical and biopharmaceutical ***’s disease(AD)is a protein-misfolding disease,and the interactions between 40-amino-acid-residueβ-amyloid peptide(Aβ_(40)) and its N-terminal truncated peptide Aβ_(11-40) demonstrate that Aβ_(11-40) may play an important role in the pathological process of ***,the effect of inhibitors on Aβ_(11-40) aggregation and on the cross-amyloid aggregation(coassembly)between Aβ_(40) and Aβ_(11-40) has never been ***,coaggregation and seeding interactions between Aβ_(40) and Aβ_(11-40) as well as the effect of epigallocatechin gallate(EGCG),a small molecule inhibitor,on the cross-amyloid aggregation have been investigated by extensive *** is found that Aβ_(11-40) participates in the aggregation of Aβ_(40) and leads to the formation of coaggregates that contain lessβ-sheet structures than pure Aβ_(40) *** aggregation kinetics along with morphologies and secondary structures of the coaggregates are also significantly affected by the Aβ_(40)/Aβ_(11-40) *** accelerates the nucleation of Aβ_(40) but retards that of Aβ_(11-40) by affecting their elongation and secondary nucleation processes in solution and on solid ***,EGCG makes the conformations of the seeding-induced Aβaggregates more compact,especially for the homologous *** titration calorimetry measurement indicates that hydrophobic interactions mainly contribute to the inhibition of the two Aβisoforms by *** findings of this research have provided new insights into Aβaggregation and the effect of an important inhibitor and the results would benefit in the development of potent inhibitors against co-assembly of different amyloid proteins.

关键词： Protein Aggregation Kinetics Nucleation Elongation Molecular interactions

Optimization of extraction method for quantitative analysis of Si/Al in soil phytoliths

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Acta Geochimica 2023年第6期42卷 1007-1016页

作者： Yongsheng Chu yue xia xiaoying Li Fushun Wang School of Environmental and Chemical Engineering Shanghai University99 Shangda RoadBaoshanP.O.Box 144Shanghai 200433China

Elemental information carried by phytoliths plays a crucial indicative role in geochemical *** instance,it serves as an indicator of the carbon pool effect in phytoliths and aids in the elucidation of silicon ***,early extraction methods for soil phytoliths primarily focused on obtaining their morphological and quantitative information,lacking efficient techniques for quantitative elemental *** this study,we aimed to extract Si/Al information from soil *** the need for complete extraction of phytolith,six extraction methods were developed and further by alkaline dissolution to determine Si/*** methods were compared in terms of enrichment capacity,the weight of extracted phytoliths,and Si/Al *** results indicated that the addition of Ammonia-Catechol in the commonly used heavy liquid flotation method effectively improved phytolith extraction capability and the accuracy of Si/Al ***,the inclusion of an acetic acid step before alkaline dissolution further removed surface-adsorbed impurities and enhanced the analytical quality of Si/Al in *** comparison of the data in this study with other published data shows that our method is relatively *** improved method proposed in this study can provide a new idea for the quantitative analysis of other elements in soil phytoliths.

关键词： Soil phytolith Extraction method Silica–aluminum ratio Ammonia–Catechol

Efficiently Improving Ensemble Forecasts of Warm-Sector Heavy Rainfall over Coastal Southern China: Targeted Assimilation to Reduce the Critical Initial Field Errors

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Journal of Meteorological Research 2023年第4期37卷 486-507页

作者： Xinghua BAO Rudi xia Yali LUO Jian yue State Key Laboratory of Severe Weather Chinese Academy of Meteorological Sciences(CAMS)China Meteorological Administration(CMA)Beijing 100081 Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters(CIC-FEMD) Nanjing University of Information Science&TechnologyNanjing 210044 CMA Earth System Modeling and Prediction Centre China Meteorological AdministrationBeijing 100081

Warm-sector heavy rainfall events over southern China are difficult to accurately forecast, due in part to inaccurate initial fields in numerical weather prediction models. In order to determine an efficient way of reducing the critical initial field errors, this study conducts and compares two sets of 60-member ensemble forecast experiments of a warm-sector heavy rainfall event over coastal southern China without data assimilation(NODA) and with radar radial velocity data assimilation(RadarDA). Yangjiang radar data, which can provide offshore high-resolution wind field information, were assimilated by using a Weather Research and Forecasting(WRF)-based ensemble Kalman filter(EnKF) system. The results show that the speed and direction errors of the southeasterly airflow in the marine boundary layer over the northern South China Sea may primarily be responsible for the forecast errors in rainfall and convection evolution. Targeted assimilation of radial velocity data from the Yangjiang radar can reduce the critical initial field errors of most members, resulting in improvements to the ensemble forecast. Specifically, RadarDA simulations indicate that radial-velocity data assimilation(VrDA) can directly reduce the initial field errors in wind speed and direction, and indirectly and slightly adjust the initial moisture fields in most members, thereby improving the evolution features of moisture transport during the subsequent forecast period. Therefore, these RadarDA members can better capture the initiation and development of convection and have higher forecast skill for the convection evolution and rainfall. The improvement in the deterministic forecasts of most members results in an improved overall ensemble forecast performance. However, VrDA sometimes results in inappropriate adjustment of the initial wind field,so the forecast skill of a few members decreases rather than increases after VrDA. This suggests that a degree of uncertainty remains about the effect of

关键词： ensemble forecast targeted assimilation warm-sector heavy rainfall

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荧光假单孢菌的生防遗传改良

天津农业科学 2001年第3期7卷 4-7页

作者：许长蔼岳东霞陈融范环陈秀为天津市农业生物工程研究中心天津300192

综述了荧光假单孢菌生物防治方面的分子生物学研究进展，提出了通过遗传工程手段进一步改良的可行途径。

关键词：荧光假单孢菌生物防治遗传改良

Information networks fusion based on multi-task coordination

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Frontiers of Computer Science 2021年第4期15卷 121-132页

作者： dong LI Derong SHEN yue KOU Tiezheng NIE School of Computer Science&Engineering Northeastern UniversityShenyang 110004China School of Information Liaoning UniversityShenyang 110036China

Information networks provide a powerful representation of entities and the relationships between *** networks fusion is a technique for information fusion that jointly reasons about entities,links and relations in the presence of various ***,existing methods for information networks fusion tend to rely on a single task which might not get enough evidence for *** order to solve this issue,in this paper,we present a novel model called MC-INFM(information networks fusion model based on multi-task coordination).Different from traditional models,MC-INFM casts the fusion problem as a probabilistic inference problem,and collectively performs multiple tasks(including entity resolution,link prediction and relation matching)to infer the final result of ***,we define the intra-features and the inter-features respectively and model them as factor graphs,which can provide abundant evidence to ***,we use conditional random field(CRF)to learn the weight of each feature and infer the results of these tasks simultaneously by performing the maximum probabilistic *** demonstrate the effectiveness of our proposed model.

关键词： information networks fusion multi-task coordination conditional random field inference