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Targets capture by distributed active swarms via bio-inspired reinforcement learning

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 210-221页

作者： Kun Xu yue li Jun Sun Shuyuan Du Xinpeng Di Yuguang Yang Bo li Institute of Biomechanics and Medical Engineering Applied Mechanics Laboratory Department of Engineering MechanicsTsinghua University Institute of Nuclear and New Energy Technology Tsinghua University Shanghai Aerospace Control Technology Institute Shanghai Key Laboratory of Aerospace Intelligent Control Technology College of Automation Engineering Nanjing University of Aeronautics and Astronautics

Natural swarms arranged from cells to herds are usually decentralized but display intriguing collective intelligence in coordinating individuals across large scales to efficiently achieve their common goals. Learning from nature may provide new strategies for controlling collective dynamics of synthetic swarms to accomplish specific functions. Here, we present a bioinspired computational framework that steers distributed active swarms to collectively capture and merge targets via reinforcement learning. We exploit collective milling structures of natural herds to cage the targets, and adopt a switching control policy inspired by sperms' chiral dynamics to optimize the trajectories of individuals, through which the active swarms can selforganize to enclose single or multiple distant targets in a dynamical, adaptive and scalable manner. There exists a critical swarm size, beyond which the excessive competition between agents would generate large mechanical forces, leading to capture instability but enabling the transition from short-distance to long-distance merging capture of multiple targets. This work provides physical insights into distributed active swarms and could offer a multilevel, decentralized strategy toward controlling swarm robotics in wide applications such as bio-medical devices, machine immunity, and target clearance.

关键词： swarm intelligence robotics multi-tasks artificial intelligence bionics

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Return to work in young and middle-aged colorectal cancer survivors:Factors influencing self-efficacy,fear,resilience,and financial toxicity

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World Journal of Gastroenterology 2025年第1期31卷 79-92页

作者： Dan Hu yue li Hua Zhang lian-lian Wang Wen-Wen liu Xin Yang Ming-Zhao Xiao Hao-ling Zhang Juan li Department of Nursing The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Nursing National Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChildren’s Hospital of Chongqing Medical UniversityChongqing 400014China Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Biomedical Science Advanced Medical and Dental InstituteUniversity Sains MalaysiaPenang 13200Malaysia Academic Affairs Office The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social ***,these survivors encounter significant challenges during their RTW ***,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC *** To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW *** A cross-sectional investigation was adopted in this *** September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in *** investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and *** analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were *** A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 *** regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(Plitating their timely reintegration into mainstream society.

关键词： Return to work Colorectal neoplasms Return-to-work self-efficacy Fear of progression Family resilience Financial toxicity

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Relationship between parenting stress and behavioral and emotional problems in preschool children: A mediation effect analysis

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World Journal of Psychiatry 2025年第1期15卷 128-136页

作者： Zhi-Wei Fu yue-Jing li Ran Yu Rui-Qing Guo li-Xia Gao Sheng-Xia Zhao Department of Children's Health Shijiazhuang Maternity and Child Healthcare HospitalShijiazhuang 050000Hebei ProvinceChina

BACKGROUND Emotional reactions,such as anxiety,irritability,and aggressive behavior,have attracted clinical attention as behavioral and emotional problems in preschool-age *** To investigate the current status of family rearing,parental stress,and behavioral and emotional problems of preschool children and to analyze the mediating effect of the current status of family rearing on parental stress and behavioral/emo-tional *** We use convenience sampling to select 258 preschool children in the physical examination center of our hospital from October 2021 to September *** children and their parents were evaluated using a questionnaire ***'s correlation was used to analyze the correlation between child behavioral and emotional problems and parental stress and family rearing,and the structural equation model was constructed to test the mediating *** The score for behavioral/emotional problems of 258 preschool children was(27.54±3.63),the score for parental stress was(87.64±11.34),and the score for parental family rearing was(31.54±5.24).There was a positive correlation between the behavioral and emotional problems of the children and the“hostile/mandatory”parenting style;meanwhile,showed a negative correlation with the“support/participation”parenting style(all Plinical medical staff should provide correct and reasonable parenting advice to their parents to promote the mental health of preschool-age children.

关键词： Preschool children Parenting stress Children's behavioral and emotional problems Family rearing Mediating effect

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Role of nutrition in diabetes mellitus and infections

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World Journal of Clinical Cases 2025年第3期13卷 1-8页

作者： Xue-Lu Yu li-Yun Zhou Xiao Huang Xin-yue li Ming-Ke Wang Ji-Shun Yang Naval Medical Center of PLA Naval Medical UniversityShanghai 200052China

In this editorial,we have commented on the article that has been published in the recent issue of World Journal of Clinical *** authors have described a case of unilateral thyroid cyst and have opined that the acute onset of infection may be linked to diabetes mellitus(DM).We have focused on the role of nutrition in the association between DM and *** with DM are at a high risk of infection,which could also be attributed to nutrition-related *** interventions for patients with diabetes are mainly based on a low-calorie diet,which can be achieved by adhering to a low-carbohydrate ***,dietary fiber supplementation is recommended to maintain the diversity of the gut ***,high-quality protein can prevent the increased risk of infection due to *** of vitamins C,vitamins A,vitamins D,and folic acid improves blood sugar control and facilitates immune *** deficiencies augment the risk of infection,but the relationship with diabetes is mostly U-shaped and a good intake should be maintained.

关键词： Diabetes mellitus Infection Macronutrients Vitamins Minerals

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司法职业教育教学学术研究的理论阐释与行动方案

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职业技术 2025年第1期24卷 32-38页

作者：李悦深圳职业技术大学经济学院深圳518055

司法职业教育所对接的并非市场经济意义的产业,专门人才培养有必要着眼于法治工作队伍“长尾”,满足基层法律服务和法律职业辅助等地方法治建设的实际需要。为培养德法兼修的法治人才,需在教学中开展“将教学界定为学术”的教学学术研... 详细信息

司法职业教育所对接的并非市场经济意义的产业,专门人才培养有必要着眼于法治工作队伍“长尾”,满足基层法律服务和法律职业辅助等地方法治建设的实际需要。为培养德法兼修的法治人才,需在教学中开展“将教学界定为学术”的教学学术研究。司法职业教育的教学学术研究在同行评价基础上,开展司法职业教育的理论构建和教学实施活动,促进教学质量提升的同时实现教师发展。基于我国司法职业教育师资队伍存在的学历层次和技能构成问题,论证了在司法职业教育领域开展教学学术研究的高度必要性和现实可能性,提出激发教师开展教学学术研究动力、加强理论与实践融合共进、明确教学学术研究效果的评价标准,从而助力教学学术研究的最终落地。

关键词：司法职业教育教学学术研究学生参与教学学术实践

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红树莓生物活性成分及功效研究进展

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食品科学 2025年第2期46卷 268-279页

作者：孙华军崔方正刘盈朱思静李跃黑龙江八一农垦大学食品学院黑龙江大庆163319

红树莓是蔷薇科悬钩子属果树,红树莓的果实、叶片、种子等部位富含多糖、黄酮类和酚类化合物等生物活性物质,具有提高免疫力、预防心血管疾病、抑制癌细胞生长等多种健康功效,是具有商业应用价值和药物研究价值的“黄金水果”。本文全... 详细信息

红树莓是蔷薇科悬钩子属果树,红树莓的果实、叶片、种子等部位富含多糖、黄酮类和酚类化合物等生物活性物质,具有提高免疫力、预防心血管疾病、抑制癌细胞生长等多种健康功效,是具有商业应用价值和药物研究价值的“黄金水果”。本文全面综述红树莓不同品种、采收期、组织部位的营养成分及含量,系统阐述红树莓不同部位在抗氧化、抗炎、抗菌、抗癌、改善代谢综合征等方面的功效和作用机制以及应用,以期为红树莓的功效研究、高值化利用和精深加工研究提供参考。

关键词：红树莓生物活性物质资源开发加工利用

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Improved Hungarian algorithm for assignment problems of serial-parallel systems

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Journal of Systems Engineering and Electronics 2016年第4期27卷 858-870页

作者： Tingpeng li yue li Yanling Qian Science and Technology on Integrated Logistics Support Laboratory National University of Defense Technology

In order to overcome the shortcoming of the classical Hungarian algorithm that it can only solve the problems where the total cost is the sum of that of each job, an improved Hungarian algorithm is proposed and used to solve the assignment problem of serial-parallel systems. First of all, by replacing parallel jobs with virtual jobs, the proposed algorithm converts the serial-parallel system into a pure serial system, where the classical Hungarian algorithm can be used to generate a temporal assignment plan via optimization. Afterwards, the assignment plan is validated by checking whether the virtual jobs can be realized by real jobs through local searching. If the assignment plan is not valid, the converted system will be adapted by adjusting the parameters of virtual jobs, and then be optimized again. Through iterative searching, the valid optimal assignment plan can eventually be *** evaluate the proposed algorithm, the valid optimal assignment plan is applied to labor allocation of a manufacturing system which is a typical serial-parallel system.

关键词： Hungarian algorithm assignment problem virtual job serial-parallel system optimization

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Interleukin-6, desmosome and tight junction protein expression levels in reflux esophagitis-affected mucosa

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World Journal of Gastroenterology 2009年第29期15卷 3621-3630页

作者： Fei-yue li Yan li Department of Digestive Diseases Central Hospitalof Daqing Youtian Daqing 163000 Heilongjiang ProvinceChina Department of Digestive Diseases Shengjing Hospitalof China Medical University Shenyang 110004 LiaoningProvince China

AIM： To investigate the correlation between the expression levels of interleukin （IL）-6 and proteins in tight junctions （TJs） in the esophageal mucosa of rats modeling different types of reflux esophagitis （RE）, and the ability of aluminum phosphate to protect against RE-induced mucosal damage via these proteins. METHODS： Male SPF Wistar rats aged 56 d were divided randomly into acid RE, alkaline RE, mixed RE, and control groups. Various surgical procedures were performed to establish rat models of acid RE. At 14 d after the procedure, some of the rats started aluminum phosphate treatment. Transmission electron microscopy （TEM） was used to observe the morphological features of TJs and desmosomes in the esophageal epithelium. Immunohistochemical methods and Western blotting were used to measure expression of claudin 1, occludin, ZO-1, JAM-l, DSG-1 and IL-6; reverse transcription polymerase chain reaction （RT- PCR） was used to measure expression of mRNA of claudin 1, occludin, ZO-1, JAM-1, DSG-1 and IL-6. RESULTS： At day 14 alter the procedures, an RE model was established in all subsequently sacrificed rats of groups A, B and C. By both gross and microscopic observation, the mucosa was damaged and thickened as the disease progressed. With TEM observation, a widened intercellular space was noticed, with significantly fewer desmosomes. Immunohistochemistry showed significantly higher levels of all proteins in all RE models compared to control rats at 3 d after operation （65.5% ± 25.6% vs 20.5% ± 2.1%, P 〈 0.05, respectively）. At 14 d after operation, along with continuing hyperplasia in the basal layer, the expression of TJ proteins in individual cells gradually decreased （12.4% ± 2.1% vs 20.5% ± 2.1%, P 〈 0.05, respectively）. Western blottings and RT-PCR showed a directly proportional increase in IL-6 levels in relation to TJ proteins, as compared to controls （0.878 ± 0.024 vs 0.205 ± 0.021 and 0.898±0.022 vs 0.205 ± 0.021, P 〈 0.05, respectively）. Upon treatment with

关键词： Reflux esophagitis Desmosome Tightjunction Proteins Mucosa

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An SOR Implicit Time-accurate Scheme in Calculating Unsteady Flows

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Chinese Journal of Aeronautics 2007年第3期20卷 202-209页

作者： li yue-jun YAN Chao School of Aeronautic Science and Engineering Beijing University of 4eronautics andAstronautics Beijing 100083 China

A new time-accurate marching scheme for unsteady flow calculations is proposed in the present work. This method is the combination of classical Successive Over-Relaxation （SOR） iteration method and Jacobian matrix diagonally dominant splitting method of LUSGS. One advantage of this algorithm is the second-order accuracy because of no factorization error. Another advantage is the low computational cost because the Jacobian matrices and fluxes are only calculated once in each physical time step. And, the SOR algorithm has better convergence property than Gauss-Seidel. To investigate its accuracy and convergency, several unsteady flow computational tests are carded out by using the proposed SOR algorithm. Roe＇s FDS scheme is used to discritize the inviscid flux terms. Unsteady computational results of SOR are compared with the experiment results and those of Gauss-Seidel, Results reveal that the numerical results agree well with the experimental data and the second-order accuracy can be obtained as the Gauss-Seidel for unsteady flow computations. The impact of SOR factor is investigated for unsteady computations by using different SOR factors in this algorithm to simulate each computational test. Different numbers of inner iterations are needed to converge to the same criterion for different SOR factors and optimal choice of SOR factor can improve the computational efficiency greatly.

关键词： unsteady flow SOR algorithm SOR factor Gauss-Seidel

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line-of-sight rates extraction of roll-pitch seeker under anti-infrared decoy state

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Journal of Systems Engineering and Electronics 2021年第1期32卷 178-196页

作者： li yue HE Lei XIA Qunli School of Aerospace Engineering Beijing Institute of TechnologyBeijing 100081China Sichuan Institute of Aerospace Systems Engineering Chengdu 610100China

In this paper,the method of extracting guidance information such as the line-of-sight(LOS)rates under the anti-infrared decoy state for the roll-pitch seeker is *** systems which are used to describe the angles transform are *** LOS angles reconstruction model of the roll-pitch seeker in inertial space is established.A Kalman filter model for extracting LOS rates of the roll-pitch seeker is *** this model,the target performs constant acceleration(CA)model *** error model of LOS rates extraction under infrared decoy state is *** existing methods of extracting LOS rates under anti-infrared decoy state are listed in this *** from the existing methods,a novel method that uses extrapolated values of target accelerations as filter measurements is proposed to solve the guidance information extraction problem under the anti-infrared decoy *** simulations are conducted to verify the effectiveness of the proposed method under different target maneuvering models such as the CA model,the CA extended model and the singer *** simulation results show that the proposed method of extracting guidance information such as LOS rates for the rollpitch seeker under the anti-infrared decoy state is effective.

关键词： line-of-sight(LOS)rate extraction roll-pitch seeker anti-infrared decoy Kalman filter target maneuver

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