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Sex-dependent alterations in extracellular vesicles linking chronic spinal cord injury to brain neuroinflammation and neurodegeneration

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Neural Regeneration Research 2025年第2期20卷 483-484页

作者： yun li Junfang Wu Department of Anesthesiology&Shock Trauma and Anesthesiology Research(STAR)CenterUniversity of Maryland School of MedicineBaltimoreMDUSA

Traumatic spinal cord injury(SCI)is a devastating exogenous injury with long-lasting consequences and a leading cause of death and disability *** in assistive technology,rehabilitative interventions,and the ability to identify and intervene in secondary conditions have significantly increased the long-term survival rate of SCI patients,with some people even living well into their seventh or eighth *** survival changes have led neurotrauma researchers to examine how SCI interacts with brain *** health and epidemiological data showed that patients with long-term SCI can have a lower life expectancy and quality of life,along with a higher risk of comorbidities and complications.

关键词： alterations inflammation injury

Correlation between the rock mass properties and maximum horizontal stress:A case study of overcoring stress measurements

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 39-48页

作者： Peng li Meifeng Cai Shengjun Miao yuan li Yu Wang Key Laboratory of Ministry of Education for Efficient Mining and Safety of Metal Mines University of Science and Technology BeijingBeijing 100083China State Key Laboratory of Coal Resources and Safe Mining China University of Mining and TechnologyXuzhou 221116China

Understanding the mechanical properties of the lithologies is crucial to accurately determine the horizontal stress *** investigate the correlation between the rock mass properties and maximum horizontal stress,the three-dimensional(3D)stress tensors at 89 measuring points determined using an improved overcoring technique in nine mines in China were adopted,a newly defined characteristic parameter C_(ERP)was proposed as an indicator for evaluating the structural properties of rock masses,and a fuzzy relation matrix was established using the information distribution *** results indicate that both the vertical stress and horizontal stress exhibit a good linear growth relationship with *** is no remarkable correlation between the elastic modulus,Poisson's ratio and depth,and the distribution of data points is scattered and ***,there is no obvious relationship between the rock quality designation(RQD)and *** maximum horizontal stress σ_(H) is a function of rock properties,showing a certain linear relationship with the C_(ERP)at the same *** addition,the overall change trend of σ_(H) determined by the established fuzzy identification method is to increase with the increase of C_(ERP).The fuzzy identification method also demonstrates a relatively detailed local relationship betweenσ_H and C_(ERP),and the predicted curve rises in a fluctuating way,which is in accord well with the measured stress data.

关键词： overcoring stress measurements elastic modulus Poisson's ratio rock quality designation maximum horizontal stress fuzzy identification

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敷设主动约束层阻尼圆锥壳的控制特性分析

振动与冲击 2016年第9期35卷 141-146页

作者：陆静袁丽芸广西科技大学汽车与交通学院广西柳州545006

基于压电材料的本构关系和内力位移方程,考虑压电材料的正、逆压电效应,求出了压电约束层的动力学控制方程和电学控制方程。根据圆锥壳的几何特性,将变量沿周向进行傅里叶展开,可将上述方程转化为沿母线方向的一阶常微分方程的形式。结... 详细信息

基于压电材料的本构关系和内力位移方程,考虑压电材料的正、逆压电效应,求出了压电约束层的动力学控制方程和电学控制方程。根据圆锥壳的几何特性,将变量沿周向进行傅里叶展开,可将上述方程转化为沿母线方向的一阶常微分方程的形式。结合黏弹层的法向平衡方程和位移连续性条件,由主动约束层和基壳的力学方程导出层合结构的动力学方程,并将该方程与压电约束层的电学方程联立,建立了敷设主动约束层圆锥壳的机电耦合模型。然后,借助精细积分技术和叠加原理,采用速度反馈控制策略,提出了一种分析此类结构的半解析、半数值方法,并采用该方法分析了反馈系数、反馈点的布置等参数对敷设主动约束层阻尼圆锥壳振动特性和控制特性的影响。

关键词：主动约束层阻尼圆锥壳速度反馈控制策略机电耦合控制特性

Decision making module based on stochastic magnetic tunnel junctions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 202-209页

作者： Yifan Miao li Zhao Yajun Zhang Zhe yuan Center for Advanced Quantum Studies and Department of Physics Beijing Normal University Institute for Nanoelectric Devices and Quantum Computing Fudan University Interdisciplinary Center for Theoretical Physics and Information Sciences Fudan University

In biological neural systems, noise is ubiquitous but does not affect the correct decisions made in the complex cognitive ***-making in biological neural system is typically achieved by accumulating input information over a period of *** by recent developments in neurosciences, we design a decision-making module based on spintronic devices, utilizing superparamagnetic tunnel junctions as artificial neurons. The feasibility of this decision-making module is verified through circuit simulations. Taking a multi-layer perceptron as an example, the module significantly improves the accuracy of the perceptron in the handwritten digit recognition task. Furthermore, the spintronic decision-making module offers advantages over the conventional pooling methods, such as adaptive decision time, high performance and the absence of analog-to-digital conversion. The decision-making module is flexible to be integrated into artificial neural networks and provides a general yet effective solution to enhance performance against device noise.

关键词： neuromorphic computing spintronics magnetic tunnel junction neural networks

一种深基坑排桩支护结构内力位移矩阵分析法解答及工程应用

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岩土力学 2024年第S01期45卷 579-595页

作者：肖荣军马威李锋袁丽云广东省佛山地质局广东佛山528000

基于平面弹性地基梁法,采用结构力学矩阵分析法,进一步完善已往工作推导公式解答的缺陷。传统的平面桩支撑解答计算理论局限于计算支护面桩体的内力和变形,没有解决xoy水平面支撑轴力计算问题,但真三维解答推导过于复杂,通常三维模型计... 详细信息

基于平面弹性地基梁法,采用结构力学矩阵分析法,进一步完善已往工作推导公式解答的缺陷。传统的平面桩支撑解答计算理论局限于计算支护面桩体的内力和变形,没有解决xoy水平面支撑轴力计算问题,但真三维解答推导过于复杂,通常三维模型计算依托有限元软件。与传统二维排桩支护模型相比,在以往的工作基础上,推导出考虑开挖过程、桩-土-冠梁-支撑共同作用的支护面位移、受力矩阵解答方程组和xoy水平面计算支撑轴力计算方法,并利用FORTRAN语言编制的程序求解。依托工程实践项目分析冠梁、腰梁、支护桩、支撑位移和内力在空间效应下的变化规律并与有限元法、理正深基坑计算结果及经非线性回归处理监测数据对比分析,结果表明,考虑开挖过程、桩-土-冠梁-支撑共同作用矩阵分析法计算出的冠梁位移具有明显的空间效应,靠近基坑角部更明显,距离坑角约1/4冠梁跨度内可以适当增加桩间距,xoy水平面坑角支撑轴力明显较中部小,与监测值能较好吻合,支撑截面和配筋计算可以针对性的优化,从而降低工程造价。冠梁、桩身位移与理正深基坑、监测数据能较好地吻合,再次验证方法的合理性与可行性,可以作为一种优化设计新方法。

关键词：深基坑排桩支护矩阵分析法内力与变形支撑轴力

IoT Empowered Early Warning of Transmission line Galloping Based on Integrated Optical Fiber Sensing and Weather Forecast Time Series Data

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Computers, Materials & Continua 2025年第1期82卷 1171-1192页

作者： Zhe li yun liang Jinyu Wang Yang Gao State Grid Henan Electric Power Company Electric Power Scientific Research Institute State Grid Henan Electric Power CompanyZhengzhou450052China

Iced transmission line galloping poses a significant threat to the safety and reliability of power systems,leading directly to line tripping,disconnections,and power *** early warning methods of iced transmission line galloping suffer from issues such as reliance on a single data source,neglect of irregular time series,and lack of attention-based closed-loop feedback,resulting in high rates of missed and false *** address these challenges,we propose an Internet of Things(IoT)empowered early warning method of transmission line galloping that integrates time series data from optical fiber sensing and weather ***,the method applies a primary adaptive weighted fusion to the IoT empowered optical fiber real-time sensing data and weather forecast data,followed by a secondary fusion based on a Back Propagation(BP)neural network,and uses the K-medoids algorithm for clustering the fused ***,an adaptive irregular time series perception adjustment module is introduced into the traditional Gated Recurrent Unit(GRU)network,and closed-loop feedback based on attentionmechanism is employed to update network parameters through gradient feedback of the loss function,enabling closed-loop training and time series data prediction of the GRU network ***,considering various types of prediction data and the duration of icing,an iced transmission line galloping risk coefficient is established,and warnings are categorized based on this ***,using an IoT-driven realistic dataset of iced transmission line galloping,the effectiveness of the proposed method is validated through multi-dimensional simulation scenarios.

关键词： Optical fiber sensing multi-source data fusion early warning of galloping time series data IoT adaptive weighted learning irregular time series perception closed-loop attention mechanism

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多孔吸声矩形薄板声振特性分析的一种新模型

振动与冲击 2016年第13期35卷 106-113,166页

作者：袁丽芸向宇陆静广西科技大学汽车与交通学院广西柳州545006 广西科技大学广西汽车零部件与整车技术重点实验室广西柳州545006

为了弥补现有多孔吸声材料在数值建模以及解析建模上的不足,建立了一种全新的多孔材料矩形薄板声振特性分析的半解析模型。利用薄板理论,引入与流体声压相关的薄膜力和力矩分量,由三维的Biot理论本退化导出了二维多孔材料矩形薄板的本... 详细信息

为了弥补现有多孔吸声材料在数值建模以及解析建模上的不足,建立了一种全新的多孔材料矩形薄板声振特性分析的半解析模型。利用薄板理论,引入与流体声压相关的薄膜力和力矩分量,由三维的Biot理论本退化导出了二维多孔材料矩形薄板的本构关系和内力-位移关系。然后,结合多孔板的骨架的平衡方程和多孔薄板内部流体的运动方程,通过Fourier变换和无量纲化处理,消去中间变量后建立了频域内多孔矩形薄板的声振控制方程,并写为一阶常微分矩阵形式,可采用高精度的齐次扩容精细积分法进行求解。该模型充分考虑了薄板面内振动与弯曲振动的相互耦合,比现有的解析模型更加接近多孔板的真实振动。同时,采用了一种高精度的齐次扩容精细积分法进行求解,可以在中高频段保证其精确性。以两端简支的多孔矩形薄板为例,分析了薄板面内振动与弯曲振动的耦合作用对声振特性的影响。

关键词：多孔吸声薄板 Biot理论薄板理论一阶常微分矩阵控制方程齐次扩容精细积分法

F-2毒素致体外培养大鼠睾丸支持细胞DNA损伤

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中国兽医学报 2007年第5期27卷 731-732,736页

作者：邬静袁莉芸袁慧湖南农业大学动物医学学院湖南长沙410128

为探讨F-2毒素对雄性生殖机能的影响,取大鼠睾丸支持细胞进行体外培养,运用单细胞凝胶电泳技术检测51、0、20和40 mg/L的F-2毒素攻毒后24 h支持细胞DNA的损伤情况。结果显示,F-2毒素在一定浓度范围内对体外培养的支持细胞DNA产生损伤作... 详细信息

为探讨F-2毒素对雄性生殖机能的影响,取大鼠睾丸支持细胞进行体外培养,运用单细胞凝胶电泳技术检测51、0、20和40 mg/L的F-2毒素攻毒后24 h支持细胞DNA的损伤情况。结果显示,F-2毒素在一定浓度范围内对体外培养的支持细胞DNA产生损伤作用,且受损程度随着F-2毒素攻毒剂量而升高,具有明显量效关系。除5 mg/L剂量组外,其余各组的细胞受损率、彗星尾长和DNA损伤程度与阴性对照组相比差异极显著(P<0.01),表明F-2毒素对体外培养的大鼠睾丸支持细胞有毒性作用,能够损伤细胞DNA。

关键词：大鼠 F-2毒素支持细胞单细胞凝胶电泳 DNA损伤

Resistance of Cement-based Grouting Materials with Nano- SiO_(2) Emulsion to Chloride Ion Penetration

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 114-119页

作者： li Shuiping CHENG Jian WEI Chao yuan Bin YU Chengxiao College of Architectural Science and Engineering Yangzhou UniversityYangzhou 225127China

The chloride penetration resistance of cement-based grout materials was improved by nano-silica *** of mixtures containing different nano-silica particles or emulsions were exposed in sodium chloride solutions of specific concentrations with different test *** properties of the mixes were assessed in terms of weight loss and compressive strength.X-ray diffraction(XRD)and scanning electron microscopy(SEM)of mixes were performed to analysis the phase evolution and *** results demonstrated that the introduction of nano-SiO_(2) emulsion significantly decreased the compressive strength loss and calcium hydroxide(CH)crystal content of hydration production,and then enhanced the resistance of cement-based grouting materials to chloride ion *** improvement derives from the filling and pozzolanic effects of nano-SiO_(2) particles,which were incorporated via an emulsion and attributed to a well dispersion in grouting matrix.

关键词： grouting materials nano-SiO_(2)emulsion chloride ion penetration,weight loss strength loss