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Flat Supercontinuum Generation within the Telecommunication Wave Bands in a Photonic Crystal Fiber with Central Holes

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Chinese Physics Letters 2012年第5期29卷 126-128页

作者： HAN Ying hou lan-tian zhou gui-yao yuan jin-hui XIA Chang-Ming wang wei wang Chao hou Zhi-yun College of Information Science and Engineering Yanshan UniversityQinhuangdao 066004 Key Laboratory of Metastable Material Science and Technology Yanshan UniversityQinhuangdao 066004 School of Information and Optoelectronic Science and Engineering South China Normal UniversityGuangzhou 510006 State Key Laboratory of Information Photonics and Optical Communications Beijing University of Posts and TelecommunicationsBeijing 100876

Flat supercontinuum in the telecommunication wave bands of E+S+C is generated by coupling a train of femtosecond pulses generated by a mode-locked Ti:sapphire laser into the fundameutal mode of a photonic crystal fiber with central holes fabricated in our lab. The pulse experiences the anomalous dispersion regime,and the soliton dynamic effect plays an important role in supercontinuum *** output spectrum in the wavelength range of 1360 1565nm does not include significant ripples due to higher pump peak power,and the normalized intensity shows less fluctuation.

关键词： pump Crystal soliton

Widely Wavelength-Tunable Blue-Shifted Dispersive Waves for Broadband Visible Wavelength Generation in a Photonic Crystal Fiber Cladding

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Chinese Physics Letters 2012年第10期29卷 62-64页

作者： yuan jin-hui SANG Xin-Zhu YU Chong-Xiu SHEN Xiang-wei wang Kui-Ru YAN bin-bin HAN Ying zhou gui-yao hou lan-tian State Key Laboratory of Information Photonics and Optical Communications Beijing University of Posts and TelecommunicationsBeijing 100876 Institute of Infrared Optical Fibers and Sensors Physics DepartmentYanshan UniversityQinhuangdao 066004 School of Information and Optoelectronic Science and Engineering South China Normal UniversityGuangzhou 510006

Blue-shifted dispersive waves(DWs)are efficiently generated from the red-shifted solitons by coupling the 120 fs pulses into the fundamental mode of the multi-knots of a photonic crystal fiber *** the femtosecond pulses at the wavelength of 825 nm and the average power of 300 mW are coupled into knots 1–3,the conversion efficiencyηDW of 32%and bandwidth BDW of 50 nm are *** ultrashort pulses generated by the DWs can be tunable over the whole visible wavelength by adjusting the wavelengths of the pump pulses coupled into different *** can be believed that this widely wavelength-tunable ultrashort visible pulse source has important applications in ultrafast photonics and resonant Raman scattering.

关键词： tunable ultrashort pump

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可见光波段空芯光子晶体光纤的实验研究

光电子．激光 2008年第9期19卷 1150-1153页

作者：苑金辉侯蓝田魏东宾王海云周桂耀燕山大学信息科学与工程学院燕山大学红外光纤与传感研究所河北秦皇岛066004

通过合理设计并采用改进的两次堆积法制备出了结构完整的空芯光子晶体光纤(HC-PCF)。从实验中测得的透射谱可以看出,所制备的光纤在450～1100nm波段出现了5条宽窄不同的带隙结构。令人欣喜的是,最后观测到空芯中有显著的绿光传出。将带... 详细信息

通过合理设计并采用改进的两次堆积法制备出了结构完整的空芯光子晶体光纤(HC-PCF)。从实验中测得的透射谱可以看出,所制备的光纤在450～1100nm波段出现了5条宽窄不同的带隙结构。令人欣喜的是,最后观测到空芯中有显著的绿光传出。将带隙传光区域由近红外波段移至可见光波段,既有利于实验中带隙的观测,又为空芯光纤在可见光波段的应用开辟了广阔的前景。

关键词：改进的两次堆积拉制法空芯光子晶体光纤透射谱可见光波段带隙结构

Activin A receptor type 1C single nucleotide polymorphisms associated with esophageal squamous cell carcinoma risk in Chinese population

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 39-51页

作者： Si-yun Lin hou Huang jin-Jie Yu Feng Su tian Jiang Shao-yuan Zhang Lu Lv Tao Long hui-Wen Pan Jun-Qing Qi Qiang zhou wei-Feng Tang Guo-Wen Ding Li-Ming wang Li-Jie Tan Jun Yin Department of Thoracic Surgery Zhongshan Hospital Affiliated to Fudan UniversityShanghai 200032China Shanghai Key Laboratory of Clinical Geriatric Medicine Huadong Hospital Affiliated to Fudan UniversityShanghai 200040China Department of Cardiothoracic Surgery The Affiliated People's Hospital of Jiangsu UniversityZhenjiang 212002Jiangsu ProvinceChina Department of Thoracic Surgery Sichuan Cancer Hospital&InstituteChengdu 610042Sichuan ProvinceChina Department of Cardiothoracic Surgery Nanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjing 210000Jiangsu ProvinceChina Department of Respiratory and Critical Care Medicine Shanghai Xuhui Central HospitalShanghai 200032China

BACKGROUND Transforming growth factor-β(TGF-β)superfamily plays an important role in tumor progression and *** A receptor type 1C(ACVR1C)is a TGF-βtype I receptor that is involved in tumorigenesis through binding to dif-ferent *** To evaluate the correlation between single nucleotide polymorphisms(SNPs)of ACVR1C and susceptibility to esophageal squamous cell carcinoma(ESCC)in Chinese Han *** In this hospital-based cohort study,1043 ESCC patients and 1143 healthy controls were *** SNPs(rs4664229,rs4556933,rs77886248,rs77263459,rs6734630)of ACVR1C were assessed by the ligation detection reaction ***-weinberg equilibrium test,genetic model analysis,stratified analysis,linkage disequi-librium test,and haplotype analysis were *** Participants carrying ACVR1C rs4556933 GA mutant had significantly decreased risk of ESCC,and those with rs77886248 TA mutant were related with higher risk,especially in older male *** the haplotype analysis,ACVR1C Trs4664229Ars4556933Trs77886248Crs77263459Ars6734630 increased risk of ESCC,while Trs4664229Grs4556933Trs77886248Crs77263459Ars6734630 was associated with lower susceptibility to *** ACVR1C rs4556933 and rs77886248 SNPs were associated with the susceptibility to ESCC,which could provide a potential target for early diagnosis and treatment of ESCC in Chinese Han population.

关键词： Activin A receptor type 1C Single nucleotide polymorphisms Esophageal squamous cell carcinoma Genetic susceptibility Hospital-based cohort study

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一种新型的多包层光子晶体光纤的分析方法

物理学报 2008年第5期57卷 3011-3015页

作者：魏东宾周桂耀赵兴涛苑金辉孟佳王海云侯蓝田燕山大学红外光纤与传感研究所秦皇岛066004

传统有效折射率方法只能模拟具有相同空气孔大小的单包层光子晶体光纤.针对这一问题,提出了一种改进的有效折射率法,能够计算具有不同孔径的多包层光子晶体光纤的传输特性.并用此方法对三包层光子晶体光纤的基模有效折射率和色散等特性... 详细信息

传统有效折射率方法只能模拟具有相同空气孔大小的单包层光子晶体光纤.针对这一问题,提出了一种改进的有效折射率法,能够计算具有不同孔径的多包层光子晶体光纤的传输特性.并用此方法对三包层光子晶体光纤的基模有效折射率和色散等特性进行了数值模拟,结果与多极法模拟出的结果符合得很好.这种改进的有效折射率法拓展了传统有效折射率法的适用范围,对快速准确地分析和设计具有不同传输特性的多包层光子晶体光纤提供了理论依据.

关键词：光子晶体光纤多包层有效折射率方法色散

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平坦色散高非线性光子晶体光纤的制备与实验

光电子．激光 2008年第8期19卷 1007-1010页

作者：苑金辉侯蓝田周桂耀高飞王康燕山大学信息科学与工程学院燕山大学红外光纤与传感研究所河北秦皇岛066004

运用改进的全矢量有效折射率法（IFVEIM），课题组自行设计了一种在900nm附近具有低平坦色散高非线性特性的光子晶体光纤。并且在改进工艺的基础上，采用中心抽真空挤压法对其进行了制备。虽然所制得光纤的结构参数与理论设计值存在一... 详细信息

运用改进的全矢量有效折射率法（IFVEIM），课题组自行设计了一种在900nm附近具有低平坦色散高非线性特性的光子晶体光纤。并且在改进工艺的基础上，采用中心抽真空挤压法对其进行了制备。虽然所制得光纤的结构参数与理论设计值存在一定的偏差，但其在所研究波段内色散值仅为0．5ps／km／nm，非线性系数值则达到了35（w＊km）^-1，这在当前规则结构的纯硅光子晶体光纤中已经很高。最后，我们对其进行了非线性实验测试，其在400-1400nm的波段范围内展现出了宽平坦的超连续谱。

关键词：光子晶体光纤改进的全矢量有效折射率法低平坦色散高非线性中心抽真空挤压法超连续谱

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三种低损耗低平坦色散光子晶体光纤的设计

半导体光电 2008年第4期29卷 535-539页

作者：苑金辉侯蓝田魏东宾王海云孟佳燕山大学信息科学与工程学院红外光纤与传感研究所河北秦皇岛066004

运用多极法理论，以内四层为研究对象，在三种情况下通过改变包层孔孔径d，设计了三种结构的光子晶体光纤。在包层中内四层空气孔孔径变化，而孔间距保持不变的情况下，数值模拟了其色散系数、限制损耗和基模有效折射率随波长变化的关... 详细信息

运用多极法理论，以内四层为研究对象，在三种情况下通过改变包层孔孔径d，设计了三种结构的光子晶体光纤。在包层中内四层空气孔孔径变化，而孔间距保持不变的情况下，数值模拟了其色散系数、限制损耗和基模有效折射率随波长变化的关系和光波模场的存在情况。模拟过程充分展示了所设计的光纤在1．2～1．8μm的宽波段范围内具有低损耗、低平坦色散的传输特性。

关键词：光子晶体光纤多极法低损耗低平坦色散

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平坦色散高非线性光子晶体光纤的研究与制备

激光与红外 2008年第3期38卷 270-274页

作者：苑金辉侯蓝田魏东宾王海云周桂耀燕山大学信息科学与工程学院燕山大学红外光纤与传感研究所河北秦皇岛066004

运用改进的全矢量有效折射率法（IFVEIM）,研究了光子晶体光纤结构（PCF）参数改变时,光纤的色散系数、有效模场面积和非线性系数随波长的变化规律,深入地分析了光纤可调节的色散平坦特性和高非线性特性。课题组自行设计了一种在900nm... 详细信息

运用改进的全矢量有效折射率法（IFVEIM）,研究了光子晶体光纤结构（PCF）参数改变时,光纤的色散系数、有效模场面积和非线性系数随波长的变化规律,深入地分析了光纤可调节的色散平坦特性和高非线性特性。课题组自行设计了一种在900nm附近具有低平坦色散高非线性特性的光子晶体光纤。并且在改进工艺的基础上,采用包层孔充气挤压法对其进行了制备,虽然制得的光纤各参数未达到设计值,但其在800~1000nm的波段内色散值仅为0.75ps/km/nm,非线性系数值则达到了30（W/km）-1,这在当前规则结构的纯硅光子晶体光纤中已经较高。

关键词：光子晶体光纤改进的全矢量有效折射率法平坦色散高非线性包层孔充气挤压法

Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China

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Biomedical and Environmental Sciences 2020年第12期33卷 893-905页

作者： MA Yan ZHU dong Shan CHEN Ren Bo SHI Nan Nan LIU Si Hong FAN Yi Pin WU gui hui YANG Pu Ye BAI Jiang Feng CHEN Hong CHEN Li Ying FENG Qiao GUO Tuan Mao hou Yong HU gui Fen HU Xiao Mei HU yun Hong HUANG jin HUANG Qiu Hua HUANG Shao Zhen JI Liang jin hai Hao LEI Xiao LI Chun Yan LI Min Qing LI Qun Tang LI Xian Yong LIU Hong De LIU jin Ping LIU Zhang MA Yu Ting MAO Ya MO Liu Fen NA hui wang jing wei SONG Fang Li SUN Sheng wang dong Ting wang Ming Xuan wang Xiao Yan wang Yin Zhen wang Yu dong WU wei WU lan Ping XIAO Yan Hua XIE hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia YANG Chun YANG Kai Jun yuan Sheng Li ZHANG Gong Qi ZHANG jin Bo ZHANG Lin Song ZHAO Shu Sen ZHAO Wan Ying ZHENG Kai zhou Ying Chun ZHU Jun Teng ZHU tian Qing ZHANG Hua Min wang Yan Ping wang Yong Yan 无 Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China Centre for Health Management and Policy Research School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012ShandongChina Institute of Information on Traditional Chinese Medicine China Academy of Chinese Medical SciencesBeijing 100700China Department of Tuberculosis The Public Health Clinical Center of ChengduChengdu 610066SichuanChina Department of Infectious Disease Shaanxi Infectious Disease HospitalXi'an 610113ShaanxiChina Department of Infectious Disease Yulin Chinese Medicine HospitalYulin 719000ShaanxiChina President's Office The First Hospital of QiqiharQiqihar 161005HeilongjiangChina Department of Traditional Chinese Medicine Shangluo Central HospitalShangluo 726000ShaanxiChina Department of Traditional Chinese Medicine The People's Hospital of QitaiheQitaihe 154603HeilongjiangChina Department of Scientific Research Xianyang Central HospitalXianyang 712000ShaanxiChina Department of traditional Chinese medicine The First Affiliated Hospital of Anhui University of Traditional Chinese MedicineHefei 230012AnhuiChina Department of Infectious Disease Heping Hospital Affiliated to Changzhi Medical CollegeChangzhi 046000ShanxiChina Department of Traditional Chinese Medicine Langfang Hospital of Chinese MedicineLangfang 065000HeibeiChina Department of Traditional Chinese Medicine Xingtai Hospital of Chinese MedicineXingtai 054001HeibeiChina Department of Traditional Chinese Medicine The People's Hospital of Guangxi Zhuang Autonomous RegionNanning 168600GuangxiChina Department of Traditional Chinese Medicine The First People'sHospital of FangchenggangFangchenggang 538001GuangxiChina Department of Traditional Chinese Medicine Mianyang Hospital of Traditional Chinese MedicineMianyang 621000SichuanChina Department of Traditional Chinese Medicine Liuzhou People's HospitalLiuzhou 545006GansuChina Department of Traditional Chinese Medici

Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains *** A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in China. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of *** Overall, 158(13.6%) patients were diagnosed with severe illness and 32(2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32), type 2 diabetes(T2 DM)(3.57, 2.32–5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–28.96), hyperlipidemia(2.15, 1.26–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–26.10)were independently linked to increased odds of being severely ill. T2 DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.25–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–29.64) within two *** Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes.

关键词： Comorbidities COVID-19 Severity Gender Age Treatment outcome