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PandaX-xT——A deep underground multi-ten-tonne liquid xenon observatory

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Science China(Physics,Mechanics & Astronomy) 2025年第2期68卷 105-120页

作者： Abdusalam Abdukerim Zihao Bo Wei Chen Xun Chen Chen Cheng Zhaokan Cheng Xiangyi Cui yingjie Fan deqing Fang lisheng Geng Karl Giboni linhui Gu Xunan guo Xuyuan guo Zhichao guo Chencheng Han Ke Han Changda He Jinrong He Di Huang Junting Huang Zhou Huang Ruquan Hou Yu Hou Xiangdong Ji Yonglin Ju Chenxiang li Jiafu li Mingchuan li Shuaijie li Tao li Qing lin Jianglai liu Congcong Lu Xiaoying Lu lingyin Luo Yunyang Luo Wenbo Ma Yugang Ma Yajun Mao Yue Meng Xuyang Ning Binyu Pang Ningchun Qi Zhicheng Qian Xiangxiang Ren Nasir Shaheed Xiaofeng Shang Xiyuan Shao guofang Shen lin Si Wenliang Sun Yi Tao Anqing wang Meng wang Qiuhong wang Shaobo wang Siguang wang Wei wang Xiuli wang Xu wang Zhou wang Yuehuan Wei Mengmeng Wu Weihao Wu yuan Wu Mengjiao Xiao Xiang Xiao Binbin yan Xiyu yan Yong yang Chunxu Yu ying yuan Zhe yuan Youhui Yun Xinning Zeng Minzhen Zhang Peng Zhang Shibo Zhang Shu Zhang Tao Zhang Wei Zhang yang Zhang yingxin Zhang yuanyuan Zhang li Zhao Jifang Zhou Ning Zhou Xiaopeng Zhou Yong Zhou Yubo Zhou Zhizhen Zhou New Cornerstone Science Laboratory Tsung-Dao Lee InstituteShanghai Jiao Tong UniversityShanghai 200240China School of Physics and Astronomy Shanghai Jiao Tong UniversityKey Laboratory for Particle Astrophysics and Cosmology(MoE)Shanghai Key Laboratory for Particle Physics and CosmologyShanghai 200240China Shanghai jiao Tong University Sichuan Research Institute Chengdu 610213China School of Physics Sun Yat-sen UniversityGuangzhou 510275China Sino-French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China department of Physics Yantai UniversityYantai 264005China Key Laboratory of Nuclear Physics and Ion-beam Application(MOE) Institute of Modern PhysicsFudan UniversityShanghai 200433China School of Physics Beihang UniversityBeijing 102206China Peng Huanwu Collaborative Center for Research and Education Beihang UniversityBeijing 100191China beijing Key Laboratory of Advanced Nuclear Materials and Physics Beihang UniversityBeijing 102206China Southern Center for Nuclear-Science Theory(SCNT) Institute of Modern PhysicsChinesen Academy of SciencesHuizhou 516000China Yalong River Hydropower development Company Ltd.Chengdu 610051China School of Mechanical Engineering Shanghai Jiao Tong UniversityShanghai 200240China department of Physics University of MarylandCollege ParkMaryland 20742USA State Key Laboratory of Particle detection and Electronics University of Science and Technology of ChinaHefei 230026China department of Modern Physics University of Science and Technology of ChinaHefei 230026China Research Center for Particle Science and Technology Institute of Frontier and Interdisciplinary ScienceShandong UniversityQingdao 266237China Key Laboratory of Particle Physics and Particle Irradiation of Ministry of Education Shandong UniversityQingdao 266237China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China School of Physics Nankai UniversityTianjin 300071China SJTU Paris Elite I

We propose a major upgrade to the existing PandaX-4T experiment at the China Jinping Underground *** new experiment,PandaX-xT,will be a multi-ten-tonne liquid xenon,ultra-low background,and general-purpose *** full-scaled PandaX-xT contains a 43-t liquid xenon active *** an experiment will significantly advance our fundamental understanding of particle physics and *** sensitivity of dark matter direct detection will be improved by nearly two orders of magnitude compared to the current best limits,approaching the so-called“neutrino floor”for a dark matter mass above 10 GeV/c^(2),providing a key test to the Weakly Interacting Massive Particle *** searching for the neutrinoless double beta decay of^(136)Xe isotope in the detector,the effective Majorana neutrino mass can be measured to a 10-41 meV/c^(2) sensitivity,providing a key test to the Dirac/Majorana nature of *** neutrinos and other ultra-rare interactions can also be measured and searched for with an unprecedented background level,opening up new windows of *** on the findings,PandaX-xT will seek the next stage upgrade utilizing isotopic separation of natural xenon.

关键词： dark matter neutrino less double beta decay astrophysical neutrinos liquid xenon

Inositol-requiring enzyme 1α is required for gut development in Xenopus lavies embryos

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World Journal of Gastroenterology 2013年第2期19卷 227-234页

作者： Jing guo Xin-Xin li jiao-jiao Feng Chen-yang yin XueJun wang Ning wang li yuan department of Biochemistry and Molecular Biology Nanjing Medical University

AIM:To investigate the role of inositol-requiring enzyme 1α(IRE1α) in gut development of Xenopus lavies ***:Xenopus embryos were obtained with in vitro fertilization and cultured in 0.1 × *** and half nanogram of IRE1α,1 ng of IRE1α-GR mRNA,1 ng of IRE1αΔC-GR mRNA,and 50 ng of IRE1α morpholino oligonucleotide(MO) or XBP1(C)MO were injected into four blastomeres at 4-cell stage for scoring the phenotype and marker gene *** rescue the effect of IRE1α MO,1 ng of IRE1α-GR mRNA was coinjected with 50 ng of *** the activation of the GR-fusion proteins,dexamethasone was prepared as 5 mmol/L stock solutions in 100% ethanol and applied to the mRNA injected embryos at desired stages in a concentration of 10 μmol/L in 0.1 × *** were kept in dexamethasone up to stage ***-mount in situ hybridization was used to determine specific gene expression,such as IRE1α,IRE1β,Xbra and Xsox17α.IRE1α protein expression during Xenopus embryogenesis was detected by Western ***:In the whole-mount in situ hybridization analysis,xenopus IRE1α and IRE1β showed quite different expression pattern during tadpole *** relatively higher expression of IRE1α was observed in the pancreas,and significant transcription of IRE1β was found in the ***1α protein could be detected at all developmental stages analyzed,from stage 1 to stage ***-of-function assay showed that IRE1α mRNA injected embryos at tailbud stage were nearly normal and the expression of the pan-mesodermal marker gene Xbra and the endodermal gene Xsox17α at stage 10.5 was not significantly changed in embryos injected with IRE1α mRNA as compared to uninjected control *** at tadpole stage,the embryos injected with IRE1α-GR mRNA did not display overt phenotype,such as gut-coiling ***-of-function assay demonstrated that the IRE1α MO injected embryos were morphologically normal before the tailbud *** did not observe a significant change of mesodermal and end

关键词： Inositol-requiring enzyme 1α XBP1 Xenopus lavies Gut development

新疆小麦过氧化物酶活性基因TaPod-A1、TaPod-A3和TaPod-D1等位变异及分布规律

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作物学报 2025年第1期51卷 68-78页

作者：刘鑫源程宇坤王丽丽战帅帅马孟瑶郭玲耿洪伟新疆农业大学农学院/新疆优质专用麦类作物工程技术研究中心新疆乌鲁木齐830052 新疆作物遗传改良与种质创新重点实验室新疆乌鲁木齐830052

小麦面粉的颜色是其品质分级的重要指标,为了使小麦面粉的品质得到进一步提升,本研究利用位于TaPod-A1、TaPod-A3和TaPod-D1位点基因的功能标记对110份新疆小麦品种(系)进行等位变异基因检测。基因型与表型方差分析结果显示, TaPod-A1、... 详细信息

小麦面粉的颜色是其品质分级的重要指标,为了使小麦面粉的品质得到进一步提升,本研究利用位于TaPod-A1、TaPod-A3和TaPod-D1位点基因的功能标记对110份新疆小麦品种(系)进行等位变异基因检测。基因型与表型方差分析结果显示, TaPod-A1、TaPod-A3和TaPod-D1位点的等位变异类型TaPod-A1b (35.5%)、TaPod-A3c (53.6%)和TaPod-D1b(60%)较其他等位变异类型TaPod-A1a (64.5%)、TaPod-A3a (46.4%)和TaPod-D1a(40%)均具有较高的POD活性。在新疆小麦材料中, TaPod-A1、TaPod-A3和TaPod-D1的3个不同基因位点上高POD活性的优异等位变异类型的分布频率均表现为引进品种(系)≈自育品种(系)>地方品种。TaPod-A3b在110份新疆小麦材料中并未检测出,说明该等位变异为稀有等位变异。具有TaPod-A1、TaPod-A3和TaPod-D1基因等位变异组合品种(系)的平均POD活性高低依次为TaPod-A1b/TaPod-A3c/TaPod-D1b (2836.25 U g^(–1) min^(–1))> TaPod-A1b/TaPod-A3c/TaPod-D1a (2796.00 U g^(–1)min^(–1))> TaPod-A1b/TaPod-A3a/TaPod-D1b(2520.31Ug^(–1)min^(–1))> TaPod-A1a/TaPod-A3c/TaPod-D1b(2473.91Ug^(–1)min^(–1))> TaPod-A1a/TaPod-A3a/TaPod-D1b(2407.65Ug^(–1)min^(–1))> TaPod-A1b/TaPod-A3a/TaPod-D1a(2339.06Ug^(–1)min^(–1))> TaPod-A1a/TaPod-A3c/TaPod-D1a(2320.38Ug^(–1)min^(–1))> TaPod-A1a/TaPod-A3a/TaPod-D1a(2210.69Ug^(–1)min^(–1))。其中,具有TaPod-A1b/TaPod-A3c/TaPod-D1b等位变异基因的活性(2836.25Ug^(–1)min^(–1))极显著高于具有TaPod-A1a/TaPod-A3a/TaPod-D1a(2210.69Ug^(–1)min^(–1))(P<0.01)的品种,说明具有较多优异等位变异类型的品种具有较高的POD活性。

关键词：小麦过氧化物酶等位变异分子标记检测

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Bibliometrics analysis based on the Web of Science:Current trends and perspective of gastric organoid during 2010-2023

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World Journal of Gastroenterology 2024年第8期30卷 969-983页

作者： Kai-lin Jiang Yue-Bo Jia Xue-jiao liu Qing-ling Jia li-kun guo Xiang-Xiang wang Ke-Ming yang Chen-Heng Wu bei-bei liang Jiang-hong ling department of Gastroenterology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 200021China Laboratory of Cancer Biology University of OxfordOxford OX37DQUnited Kingdom School of Traditional Chinese Medicine Shanghai University of Chinese MedicineShanghai 200021China Shanghai Key Laboratory of Molecular Imaging Shanghai University of Medicine and Health SciencesShanghai 201318China

BACKGROUND Three-dimensional organoid culture systems have been established as a robust tool for elucidating mechanisms and performing drug efficacy *** use of gastric organoid models holds significant promise for advancing personalized medicine ***,a comprehensive bibliometric review of this burgeoning field has not yet been *** To analyze and understand the development,impact,and direction of gastric organoid research using bibliometric methods using data from the Web of Science Core Collection(WoSCC)*** This analysis encompassed literature pertaining to gastric organoids published between 2010 and 2023,as indexed in the *** and VOSviewer were used to depict network maps illustrating collaborations among authors,institutions and keywords related to gastric ***,co-citation,and burst analysis methodologies were applied to assess the impact and progress of *** A total of 656 relevant studies were *** majority of research was published in gastroenterology-focused ***,yana Zavros,Hans Clevers,James M Wells,Sina Bartfeld,and Chen Zheng were the 5 most productive authors,while Hans Clevers,Huch Meritxell,Johan H van Es,Marc Van de Wetering,and Sato Toshiro were the foremost influential scientists in this *** from the University Medical Center Utrecht,Netherlands Institute for developmental Biology(Utrecht),and University of Cincinnati(Cincinnati,OH,United States)made the most significant ***,gastric organoids are used mainly in studies investigating gastric cancer(GC),Helicobacter pylori-infective gastritis,with a focus on the mechanisms of GC,and drug screening *** Key focus areas of research using gastric organoids include unraveling disease mechanisms and enhancing drug screening *** contributions from renowned academic institutions highlight this field’s dynamic growth.

关键词： Gastric organoid Gastric disease Bibliometrics analysis Gastric cancer Gastritis

Middle devonian ostracods from Jiwozhai patch reef(Dushan,Guizhou Province,South China):Biostratigraphic and palaeoecological implication

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Journal of Palaeogeography 2024年第3期13卷 581-593页

作者： Jun-Jun Song Jia-yuan Huang Wen guo kun liang Yu-Cong Sun Zhi-hong wang Wen-kun Qie State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and PalaeontologyChinese Academy of SciencesNanjing 210008Jiangsu ProvinceChina Hubei Key Laboratory of Paleontology and Geological Environment Evolution Wuhan Center of China Geological SurveyWuhan 430205Hubei ProvinceChina University of Chinese Academy of Sciences NanjingNanjing 211135Jiangsu ProvinceChina

The Middle devonian ostracods from the Jiwozhai patch reef in Dushan, Guizhou Province, South China were described for the first time in this study. Twenty-nine species belonging to 20 genera were identified and figured, including a new species named wangshangkia jiwozhaiensis sp. nov. The ostracod fauna in the Jiwozhai patch reef represents a Givetian age. The ostracod assemblage belongs to the smooth-podocopid association, which is also ecologically equivalent to the Eifelian Mega-Assemblage Ⅲ. This association is indicative of shallow open-marine environments. The Jiwozhai patch reef fauna is primarily comprised of suspension feeders, including filter-feeding ostracods, corals, brachiopods and bryozoans. Ostracods from the Jiwozhai patch reef were compared to the ostracod faunas from Laurentia-Baltica at generic level, which reveals limited faunal exchanges between South China and Laurentia-Baltica during the Middle devonian.

关键词： Ostracods Givetian Jiwozhai patch reef Dushan Palaeoecology

Optimal planning of stand-alone microgrids incorporating reliability

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Journal of Modern Power Systems and Clean Energy 2014年第3期2卷 195-205页

作者： Chengshan wang Bingqi jiao li guo Kai yuan Bing SUN Key Laboratory of Smart Grid of Ministry of Education Tianjin UniversityTianjin 300072China

This paper proposes a new method for the planning of stand-alone *** means of clustering techniques,possible operating scenarios are obtained considering the daily patterns of wind and load ***,an approximate analytical model for reliability evaluation of battery energy storage system is developed in terms of the diverse scenarios,along with multistate models for wind energy system and diesel generating *** optimal planning model is further illustrated based on the scenarios and the reliability models,with the objective of minimizing the present values of the costs occurring within the project lifetime,and with the constraints of system operation and ***,a typical stand-alone microgrid is studied to verify the efficiency of the proposed method.

关键词： Stand-alone microgrid Reliability evaluation Power generation planning Clustering scenarios Discrete states Multistate model

Research and development of advanced structured packing in a rotating packed bed

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Chinese Journal of Chemical Engineering 2022年第9期35卷 178-186页

作者： Zhi-guo yuan Yu-Xia wang You-Zhi liu Dan wang Wei-Zhou jiao Peng-Fei liang Shanxi Province Key Laboratory of Higee-Oriented Chemical Engineering North University of ChinaTaiyuan 030051China

As the core component of the rotating packing bed,packing is a place for efficient gas–liquid mixing and mass *** this paper,a 3D structured packing composed of a mesh structure and a support structure was *** mesh structure is a ring-shaped mesh surrounded by triangular meshes,which is stable in structure and can achieve a high degree of dispersion and aggregation of the liquid *** support structure is composed of ring-shaped structural units arranged at a certain angle along the axial direction,which can enhance the turbulence of the airflow while constructing regular gas-phase *** steel meshes of different diameters and supporting structures are alternately combined to form 3D packing,which is loaded in a layered cross-flow rotating packing *** results show that under the same operating conditions,the mass transfer performance of 3D packing and wire mesh packing are equivalent,and both are better than pall ring ***,the pressure drop of 3D packing is significantly lower than that of pall ring packing and wire mesh *** design and implementation of packing the development presented in this paper can be used to develop special structured packing for rotating bed,which can further improve the performance of rotating packed bed(RPB).

关键词： Rotating packed bed 3D printed packing 3D modeling Mass transfer Pressure drop Gas–liquid channel

Rhodium-catalyzed Doyle-Kirmse rearrangement reactions of sulfoxoniun ylides

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Chinese Chemical Letters 2024年第4期35卷 363-366页

作者： ying-Di Hao Zhi-Qian lin Xiao-Yu guo jiao liang Can-kun Luo Qian-Tao wang li guo Yong Wu Key Laboratory of Drug-Targeting and Drug delivery System of the Education Ministry and department of Medicinal Chemistry Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial TechnologyWest China School of PharmacySichuan UniversityChengdu 610041China

Doyle-Kirmse rearrangement reactions have received continuous attention as an important method for constructing complex chemical structures. Herein, we disclosed an efficient rhodium-catalyzed DoyleKirmse rearrangement reaction, which can simultaneously construct C–C bonds and C–X(X = S/Se) bonds using sulfoxonium ylides as starting materials to obtain sulfur-or selenium-containing compounds. This strategy is characterized by the safer and greener carbene precursor, high yields and broad substrate scope, possessing a wide range of application.

关键词： Sulfoxonium ylides Rhodium(Ⅱ)-catalyzed Carbene Rearrangement reactions One-pot process

Crystal Structure and Luminescence of a New Two-dimensional Sr(Ⅱ) Coordination Polymer Based on 3,5-Dinitro-salicylic Acid and 1,10-Phenanthroline

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Chinese Journal of Structural Chemistry 2015年第8期34卷 1295-1299页

作者： KONG Zhi-guo guo Sheng-Nan HE Gui-yuan li Xin-Hang jiao Yu-Qi wang Xiu-yan Key Laboratory of Preparation and Applications of Environmental Friendly Materials Jilin Normal University department of Chemistry Jilin Normal University

In this work, we report a new two-dimensional Sr（II） coordination polymer, namely, [Sr（L）（phen）（H20）] （1）, based on 3,5-dinitro-salicylic acid （H2L） and 1,10-phenanthroline （phen）. It crystallizes in monoclinic, space group P2/1 with a = 15.479（3）, b = 9.4020（19）, c = 13.884（3）/k, β= 103.76（3）°, V= 1962.5（7） A3, Z = 4, C19H12SrN4O8, Mr = 511.95, Dc = 1.733 g/cm^3, F（000） = 1024,μ（MoKa） = 2.805 mm^-1, R = 0.0411 and wR = 0.1069. In 1, each L anion bridges three Sr（II） atoms by using carboxylate and hydroxyl groups, yielding a two-dimensional layer structure. The phen ligands are alternately attached to both sides of the layer. The π-π stacking between L and phen in the same layer and hydrogen-bonding interactions between water molecule and carboxylate oxygen atom play an important role in stabilizing the layer structure of 1. The solid state luminescent property of 1 was also studied at room temperature.

关键词： crystal structure coordination polymer 3,5-dinitro-salicylic acid,