检索结果-南通市图书馆

Multilevel analysis of the central-peripheral-target organ pathway:contributing to recovery after peripheral nerve injury

引用

Neural Regeneration Research 2025年第10期20卷 2807-2822页

作者： Xizi Song Ruixin Li Xiaolei Chu Qi Li Ruihua Li Qingwen Li Kai-yu Tong Xiaosong Gu Dong ming Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Haihe Laboratory of Brain-Machine Interface and Human-Machine Fusion TianjinChina Department of Rehabilitation Tianjin University Tianjin HospitalTianjinChina Department of Hand Microsurgery Tianjin University Tianjin HospitalTianjinChina School of Exercise and Health Tianjin University of SportTianjinChina Department of Biomedical Engineering the Chinese University of Hong KongHong Kong Special Administrative RegionChina

Peripheral nerve injury is a common neurological condition that often leads to severe functional limitations and *** on the pathogenesis of peripheral nerve injury has focused on pathological changes at individual injury sites,neglecting multilevel pathological analysis of the overall nervous system and target *** has led to restrictions on current therapeutic *** this paper,we first summarize the potential mechanisms of peripheral nerve injury from a holistic perspective,covering the central nervous system,peripheral nervous system,and target *** peripheral nerve injury,the cortical plasticity of the brain is altered due to damage to and regeneration of peripheral nerves;changes such as neuronal apoptosis and axonal demyelination occur in the spinal *** nerve will undergo axonal regeneration,activation of Schwann cells,inflammatory response,and vascular system regeneration at the injury *** damage to target organs can occur,including skeletal muscle atrophy and sensory receptor *** then provide a brief review of the research advances in therapeutic approaches to peripheral nerve *** main current treatments are conducted passively and include physical factor rehabilitation,pharmacological treatments,cell-based therapies,and physical ***,most treatments only partially address the problem and cannot complete the systematic recovery of the entire central nervous system-peripheral nervous system-target organ ***,we should further explore multilevel treatment options that produce effective,long-lasting results,perhaps requiring a combination of passive(traditional)and active(novel)treatment methods to stimulate rehabilitation at the central-peripheral-target organ levels to achieve better functional recovery.

关键词： central nervous system central peripheral target organ multilevel pathological analysis nerve regeneration peripheral nerve injury peripheral nervous system target organs therapeutic approach

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

高填方黄土路堤的最优填筑密度分区研究

引用

四川大学学报（工程科学版） 2002年第1期34卷 40-43页

作者：胡小明余学明四川大学水电学院四川成都610065

根据黄土地区的工程实际状况 ,运用离心模型试验研究了黄土高路堤 (H =30m和H =6 3.8m)特性 ,获得了高路堤填土在不同干容重分区下 ,不同路堤边坡在无水、挡水、边坡淋水作用时 ,高路堤的稳定情况及其位移与应力状况。试验结果表明 :黄... 详细信息

根据黄土地区的工程实际状况 ,运用离心模型试验研究了黄土高路堤 (H =30m和H =6 3.8m)特性 ,获得了高路堤填土在不同干容重分区下 ,不同路堤边坡在无水、挡水、边坡淋水作用时 ,高路堤的稳定情况及其位移与应力状况。试验结果表明 :黄土高路堤稳定与沉降除与填筑密度密切相关外 ,水的浸入也是一个重要影响因素。在填土容重一定时 ,边坡坡度越陡 ,稳定安全性越差 ,沉降越大。

关键词：黄土高路堤稳定沉降离心模型试验填土边坡填筑密度分区公路路基工程设计

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Estimated Ultimate Recovery and Productivity of Deep Shale Gas Horizontal Wells

引用

Fluid Dynamics & Materials Processing 2025年第1期21卷 221-232页

作者： Haijie Zhang Haifeng Zhao ming Jiang Junwei Pu yuanping Luo Weiming Chen Tongtong Luo Zhiqiang Li Xinan yu Exploration and Development Department Chongqing Shale Gas Exploration and Development Co.Ltd.Chongqing401120China Oil&Gas Technology Research Institute Changqing Oilfield CompanyXi’an710018China Exploration and Development Research Institute Zhejiang Oilfield CompanyHangzhou310023China Geological Exploration and Development Research Institute Chuanqing Drilling Engineering Co.Ltd.Chengdu610056China School of Petroleum and Natural Gas Engineering Chongqing University of Science and TechnologyChongqing401331China Technology Department Chongqing University of Science and TechnologyChongqing401331China

Pressure control in deep shale gas horizontal wells can reduce the stress sensitivity of hydraulic fractures and improve the estimated ultimate recovery(EUR).In this study,a hydraulic fracture stress sensitivity model is proposed to characterize the effect of pressure drop rate on fracture ***,a production prediction model is introduced accounting for a non-uniform hydraulic fracture conductivity *** results reveal that increasing the fracture conductivity leads to a rapid daily production increase in the early ***,above 0.50 D·cm,a further increase in the fracture conductivity has a limited effect on shale gas production *** initial production is lower under pressure-controlled conditions than that under *** extended pressure control durations,the cumulative production initially increases and then *** a fracture conductivity of 0.10 D·cm,the increase in production output under controlled-pressure conditions is~35%.For representative deep shale gas wells(Southern Sichuan,China),if the pressure drop rate under controlled-pressure conditions is reduced from 0.19 to 0.04 MPa/d,the EUR increase for 5 years of pressure-controlled production is 41.0 million,with an increase percentage of~29%.

关键词： Deep shale gas fracture stress sensitivity pressure-controlled production production prediction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Literature study on traditional Chinese medicine syndromes after renal transplantation

引用

World Journal of Transplantation 2025年第1期15卷 150-155页

作者： yun-Peng Guo Ling-xue Bao yu-Yang Wang Quan Wen Gai Hang Bo Chen Tongliao Clinical Medical College Inner Mongolia Medical UniversityTongliao 028000Inner Mongolia Autonomous RegionChina Department of Urology Tongliao People's HospitalTongliao 028000Inner Mongolia Autonomous RegionChina

BACKGROUND Kidney transplantation is the most effective means to treat patients with renal failure,but its postoperative problems such as rejection reactions,immunosuppressant poisoning,chronic transplant kidney nephropathy,*** have not been effectively *** study searched for literature on traditional Chinese medicine(TCM)syndromes after kidney transplantation in China,conducted statistical analysis of the results,and sought to identify the underlying *** To understand the TCM syndromes after renal transplantation and associated rules and provide a theoretical basis for further clinical *** The literature pertaining to TCM syndromes in renal transplantation,published in the China National Knowledge Infrastructure,Wanfang database,and WIP database from 1970 to 2021,was meticulously searched and comprehensively and statistically *** Following the established inclusion and exclusion criteria,13 studies were selected for ***-renal transplantation,no significant discrepancy was noted among the groups based on the location of TCM ***,when categorized according to TCM pathogenic factors,the groups with spleen and kidney yang deficiency,as well as liver and kidney yin deficiency,exhibited a statistically significant difference in the *** Currently,the research on TCM syndromes pertaining to renal transplantation is in its nascent *** is imperative to conduct a multicentric,large-scale survey of TCM syndromes subsequent to renal transplantation in the ensuing years.

关键词： Kidney transplantation Syndrome Literature analysis Traditional Chinese medicine Systematic review

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

GLB prevents tumor metastasis of Lewis lung carcinoma by inhibiting tumor adhesion actions

引用

Acta Pharmacologica Sinica 2005年第7期26卷 881-886页

作者： Yan PAN~2 Qian-liu SONG~2 Yan-hua LIN~2 Ning LU~2 He-ming yu~3 xue-jun LI~(2,4) 2 Department of Pharmacology,School of Basic Medical Sciences and State Key Laboratory of Natural Biomimetic Drugs,Peking University,Beijing 100083,China 3 National Research Institute for Family Planning,Beijing 100081,China Department of Pharmacology School of Basic Medical Sciences and State Key Laboratory of Natural Biomimetic Drugs Peking University Beijing China National Research Institute for Family Planning Beijing China

Aim:To investigate the inhibitory effect of a new compound of GLB on tumormetastasis in vivo and analyze its actions on tumor cell adhesion to clarify ***:The effect of GLB on tumor metastasis was analyzed byLewis lung carcinoma *** pathological morphology of lung alveolar wasevaluated by hematoxylin-eosin *** effect of GLB on the proliferation ofhuman prostate cancer cell（PC-3M,with a high metastatic characteristic）wasstudied using the MTT method,and its actions on PC-3M cell adhesion to humanumbilical vein endothelial cells（HUVEC）and laminin were analyzed in ***:GLB(100 mg·kg-1·d-1for 28 d,ig)reduced the number of lung colonies ofLewis lung carcinoma metastasis significantly（P<0.05）.Simultaneously,GLBcould mitigate the damage of lung alveolar caused by metastasic tumor *** vitro,GLB inhibited dramatically the adhesion of PC-3M cells to HUVEC（P<0.01）and laminin（P<0.05）,without cytotoxic or anti-proliferative action on ***:GLB has anti-tumor metastatic activity,which partly dependson its inhibition of tumor adhesion.

关键词： neoplasm metastasis adhesion carcinoma Lewis lung

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

The interesting Host-guest interaction of cuccurbit（n=6,7,8）uril and Adduct 2-phenyl-imidazo[4,5-f]1,10-phenanthroline derivers

The interesting Host-guest interaction of cuccurbit（n=6,7,8...

引用

中国化学会全国第十二届大环第四届超分子化学学术讨论会

作者： Xiang Shuang-chun Hu yu Xiang Zhang-ming xue Sai-feng Zhu Qian-jiang TaoZhu (Institute of applied chemistry, GuiZhou Univetsity, GuiYang, 550025)

＜正＞ 2-penyl-imidazo[4,5,f]1,10-pheanthroline and 2-（p-dimethylamino）phenyl-imidazo[4,5,f]1,10-phenanthroline are synthesised. It is unusual that the imidazo section of the two guests is binded in the cavity of cucurbit[n=6,7,8]uril while the phenyl and phenanthroline sections are located at the each port of a cucurbit[n=6 or 7 or 8]uril.

关键词： Cucurbit[n=6 7 8]uril 2-phenyl-imidazo[4.5 f] 1 10-phenanthroline derivers 1HNMR

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Conjunctival microbiota variations in a subset of middleaged and elderly individuals from Beijing,China

引用

International Journal of Ophthalmology(English edition) 2025年第2期18卷 237-243页

作者： Tian-Yao Zhao yu-Chen Wang Ying-Juan Sun Jun-yue Wang Xiao-Dan Jiang xue-Min Li Ai-Hua Deng Department of Ophthalmology Peking University Third HospitalBeijing Key Laboratory of Restoration of Damaged Ocular NerveBeijing 100191China Fangshan Hospital Beijing University of Chinese Medicine Beijing 102400China CAS Key Laboratory of Pathogenic Microbiology and Immunology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China State Key Laboratory of Animal Nutrition and Feeding Ministry of Agriculture and Rural Affairs Feed Industry CentreAgricultural UniversityBeijing 100193China

AIM:To isolate and identify the conjunctival microbiota of cataract patients and analyze the associated influencing ***:This study recruited 216 participants(216 eyes)from April 2022 to July *** the condition of no antibiotic use prior to cataract surgery,sterile swabs were used to collect samples from the lower conjunctival *** cultures were then conducted,followed by species identification through 16S rDNA gene *** factors associated with positive or negative bacterial isolation rates were analyzed,including age,gender,meibomian gland dysfunction(MGD),history of hypertension,history of diabetes,history of cancer,history of infectious diseases and the habit of wearing ***:Among the 216 eyes,78 eyes yielded isolates,with an isolation rate of 36.11%,detecting a total of 122 ***-positive rods accounted for 49.18%(60 strains),gram-positive cocci accounted for 45.08%(55 strains),gram-negative bacteria accounted for 4.92%(6 strains),and fungi accounted for 0.82%(1 strain).This study found that the most abundant genera in the conjunctival sac were Corynebacterium(42.62%),Staphylococcus(31.15%),Micrococcus(9.84%),Acinetobacter(4.10%),and Bacillus(3.28%).Furthermore,age(P=0.006),gender(P=0.039),diabetes(P=0.003),history of infectious diseases(P=0.02),and duration of mask replacement(P<0.001)were important factors influencing the positive bacterial culture of the conjunctival *** hypertensive patients exhibited a higher isolation rate of conjunctival bacteria,it did not reach statistical significance,and the history of cancer did not affect the isolation rate of the conjunctival microbial community in cataract patients before ***:Potential changes are observed in the conjunctival microbiota among a sample of middleaged and elderly individuals from Beijing,***,an increased isolation rate of Corynebacterium and Micrococcus is detected,suggesting a possible change in the mic

关键词： conjunctival microbiota 16S rDNA middle-aged and elderly population mask cataract surgery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Inter‑Skeleton Conductive Routes Tuning Multifunctional Conductive Foam for Electromagnetic Interference Shielding,Sensing and Thermal Management

引用

Nano-Micro Letters 2025年第3期17卷 19-36页

作者： Xufeng Li Chunyan Chen Zhenyang Li Peng Yi Haihan Zou Gao Deng ming Fang Junzhe He Xin Sun Ronghai yu Jianglan Shui Caofeng Pan Xiaofang Liu School of Materials Science and Engineering Beihang UniversityBeijing 100191People’s Republic of China Institute of Atomic Manufacturing Beihang UniversityBeijing 100191People’s Republic of China Tianmushan Laboratory Xixi Octagon CityYuhang DistrictHangzhou 310023People’s Republic of China Science and Technology On Electromagnetic Scattering Laboratory Beijing Institute of Environmental FeaturesBeijing 100854People’s Republic of China

Conductive polymer foam(CPF)with excellent compressibility and variable resistance has promising applications in electromagnetic interference(EMI)shielding and other integrated functions for wearable ***,its insufficient change amplitude of resistance with compressive strain generally leads to a degradation of shielding performance during ***,an innovative loading strategy of conductive materials on polymer foam is proposed to significantly increase the contact probability and contact area of conductive components under *** inter-skeleton conductive films are constructed by loading alginate-decorated magnetic liquid metal on the polymethacrylate films hanged between the foam skeleton(denoted as AMLM-PM foam).Traditional point contact between conductive skeletons under compression is upgraded to planar contact between conductive ***,the resistance change of AMLM-PM reaches four orders of magnitude under ***,the inter-skeleton conductive films can improve the mechanical strength of foam,prevent the leakage of liquid metal and increase the scattering area of EM ***-PM foam has strain-adaptive EMI shielding performance and shows compression-enhanced shielding effectiveness,solving the problem of traditional CPFs upon *** upgrade of resistance response also enables foam to achieve sensitive pressure sensing over a wide pressure range and compression-regulated Joule heating function.

关键词： Inter-skeleton conductive films Conductive polymer foam Liquid metal Electromagnetic interference shielding

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Surface micro-arrays enhancing electromagnetic interference shielding of polydimethylsiloxane/multiwalled carbon nanotubes nanocomposites

引用

Nano Research 2025年第1期18卷 508-519页

作者： Ke Jiang Zhi Chen Ji yu Chen Zheng Shan Huang ming Wang Chongqing Key Laboratory of Soft-Matter Material Manufacturing School of Chemistry and Chemical EngineeringSouthwest UniversityChongqing 400715China School of Mechanics Civil Engineering and ArchitecturesNorthwestern Polytechnical UniversityXi’an 710072China Jieyang Branch of Chemistry and Chemical Engineering Guangdong Laboratory(Rongjiang Laboratory) Jieyang 515200China

Herein,the electromagnetic shielding performance of surface concave-convex(SC)and zig-zag micro-arrays was studied by using a simulation prediction and a three-dimensional(3D)printing custom ***,surface stripe concaveconvex(SSC)and surface cylindrical concave-convex(SCC)micro-arrays with or without zig-zag micro-arrays are designed,and their shielding performance is simulated in multi-bands(C-,X-band).The multiwalled carbon nanotubes/polydimethylsiloxane composites(MWCNT/PDMS)with different SC structures and different electrical conductivity are molded in acrylonitrile-butadiene-styrene copolymer(ABS)molds which are printed by a 3D *** results show that the electromagnetic interference shielding effectiveness(EMI SE)of the samples can be enhanced by constructing the SC micro-arrays with zig-zag micro-arrays,and improving with the increase of conductivity and *** addition,the shielding mechanism of the SC-MWCNT/PDMS composites is investigated and discussed by an electromagnetic simulation.

关键词： surface micro-arrays electrical properties electromagnetic interference(EMI)shielding three-dimensional(3D)printing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Passive-state preparation for quantum secure direct communication

引用

Science China(Physics,Mechanics & Astronomy) 2025年第04期Mechanics & Astronomy) .卷 39-48页

作者： Jia-Wei Ying Jin-yu Wang yu-Xiang Xiao Shi-Pu Gu Xing-Fu Wang Wei Zhong ming-ming Du Xi-yun Li Shu-Ting Shen An-Lei Zhang Lan Zhou yu-Bo Sheng College of Electronic and Optical Engineering and College of Flexible Electronics (Future Technology) Nanjing University of Posts and Telecommunications Institute of Quantum Information and Technology Nanjing University of Posts and Telecommunications College of Science Nanjing University of Posts and Telecommunications

Quantum secure direct communication（QSDC） can transmit the secret message directly. Single-photon-based QSDC protocol requires the active modulation of the quantum state of the source, potentially introducing various side-channel vulnerabilities. In this paper, we propose a passive-state preparation QSDC protocol. By utilizing a passive-state preparation method, we remove the need for active modulation, thus eliminating the side-channel risks associated with the source encoder. To evaluate the performance of the protocol, we develop a system model and improve the decoy state method. Through parameter optimization,we identify the optimal secrecy message capacity for various communication distances and compare it with active modulation QSDC. At a communication distance of 10（15） km, the secrecy message capacity of passive-state preparation QSDC reaches3.894 × 10-4（3.715 × 10-5） bit/pulse, achieving 95.3%（91.5%） of the active case's performance. Meanwhile, we consider the resource consumption and optimize the secrecy message transmission rate of passive-state preparation QSDC. Using a coherent light source with a frequency of 10～6Hz, at communication distances of 5, 10, and 15 km, the secrecy message transmission rates for passive-state preparation QSDC reach 2.370 × 10～2, 4.218 × 10, and 2.504 bit/s, respectively.

关键词：

来源：

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：