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单纯放置LVIS支架治疗颅内动脉瘤的初步经验

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中国实用神经疾病杂志 2024年第5期27卷 557-562页

作者：季金璀郭锋赵秀豪李一星于建军潍坊医学院临床医学院山东潍坊261053 临沂市人民医院山东临沂276000

目的探讨单纯使用LVIS支架治疗颅内动脉瘤(IA)的有效性和安全性。方法回顾性收集采取单纯LVIS支架治疗的45例患者临床资料,对IA的特征及影像学随访结果进行分析。结果 45例患者通过单纯放置LVIS支架共治疗48个IA。术后4~24个月接受脑... 详细信息

目的探讨单纯使用LVIS支架治疗颅内动脉瘤(IA)的有效性和安全性。方法回顾性收集采取单纯LVIS支架治疗的45例患者临床资料,对IA的特征及影像学随访结果进行分析。结果 45例患者通过单纯放置LVIS支架共治疗48个IA。术后4~24个月接受脑血管造影复查,中位复查时间7个月。Raymond分级Ⅰ级的IA 31个,Ⅱ级4个,Ⅲ级13个,总体治愈率64.58%。单LVIS支架治疗30个IA,治愈率56.67%,双LVIS支架套叠治疗18个IA,治愈率77.78%。所有患者获得出院6个月时的门诊或电话随访,均未发生严重缺血或出血事件。改良Rankin量表评分(mRS)均为0~2分。结论单纯放置LVIS支架治疗IA安全可行,但治愈率低于其辅助弹簧圈栓塞,不宜作为IA的首选治疗方案。对于术中无法填塞弹簧圈或术前不接受血流导向装置以及开颅夹闭术治疗的患者,双LVIS支架治疗可作为备选方案或术中补救措施。

关键词： LVIS支架血管内治疗颅内动脉瘤血流动力学并发症

Progress of Domestic Recombinant Human-Like Collagen Research and Application

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China Detergent & Cosmetics 2022年第2期7卷 58-62页

作者： yu jianjun Zhao Hua Zhejiang Meishangjie Biotech Co. Ltd.China

By intercepting the most effective fragment of human collagen’s gene,recombinant human-like collagen is produced by genetic engineering technology and *** collagen has good biocompatibility and can promote cell *** human-like collagen has great potential application value in medical biological materials,cosmetics and *** recent years,many specialized enterprises which are engaged in human-like collagen raw materials production have *** this paper,a brief summary of the current recombinant human-like collagen raw material’s production and its latest research and development have been made.

关键词： recombinant human-like collagen fibronectin genetic recombination biological fermentation

Desired Dynamic Equation for Primary Frequency Modulation Control of Gas Turbines

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Energy Engineering 2024年第5期121卷 1347-1361页

作者： Aimin Gao Xiaobo Cui Guoqiang yu jianjun Shu Tianhai Zhang Thermal Power Center Jiangsu Frontier Electric Technology Co.Ltd.Nanjing211102China School of Energy and Power Engineering Nanjing Institute of TechnologyNanjing211167China

Gas turbines play core roles in clean energy supply and the construction of comprehensive energy *** control performance of primary frequency modulation of gas turbines has a great impact on the frequency control of the power ***,there are some control difficulties in the primary frequency modulation control of gas turbines,such as the coupling effect of the fuel control loop and speed control loop,slow tracking speed,and so *** relieve the abovementioned difficulties,a control strategy based on the desired dynamic equation proportional integral(DDE-PI)is proposed in this *** on the parameter stability region,a parameter tuning procedure is *** is carried out to address the ease of use and simplicity of the proposed tuning ***,DDE-PI is applied to the primary frequency modulation system of an MS6001B heavy-duty gas *** simulation results indicate that the gas turbine with the proposed strategy can obtain the best control performance with a strong ability to deal with system *** proposed method shows good engineering application potential.

关键词： Gas turbine primary frequency modulation(PFM) desired dynamic equation(DDE) proportion-integral(PI)

Demonstration of DSM-OFDM-1024QAM transmission over 400 m at 335 GHz

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Science China(Information Sciences) 2023年第8期66卷 273-274页

作者： Kaihui WANG jianjun yu Weiping LI Junjie DING Feng WANG Chen WANG Wen ZHOU Jiao ZHANG Min ZHU Tangyao XIE Jianguo yu Li ZHAO Feng ZHAO Key Laboratory for Information Science of Electromagnetic Waves Fudan University Purple Mountain Laboratories School of Electrical and Electronic Engineering Beijing University of Posts and Telecommunications School of Electronic Engineering Xi'an University of Posts and Telecommunications

The terahertz(THz) band has received extensive attention and is considered a potential band for future mobile communications [1]. Up to now, 1024QAM and 2048QAM have been adopted in practical applications. For such high-order QAM(quadrature amplitude modulation) signal transmission, the current THz system is difficult to support. Considering the abundant bandwidth resources of the THz band,

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Ultra-wideband fiber-THz-fiber seamless integration communication system toward 6G: architecture, key techniques, and testbed implementation

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Science China(Information Sciences) 2023年第1期66卷 296-313页

作者： Min ZHU Jiao ZHANG Bingchang HUA Mingzheng LEI yuancheng CAI Liang TIAN Dongming WANG Wei XU Chuan ZHANG Yongming HUANG jianjun yu Xiaohu YOU National Mobile Communications Research Laboratory Southeast University Purple Mountain Laboratories School of Information Science and Technology Fudan University Peng Cheng Laboratory

Terahertz(THz) communication is widely regarded as the key component of future 6G mobile communication systems. Through comparative analysis of some of the main existing technical routes of THz up-conversion and down-conversion in THz wireless communication systems, a novel ultra-wideband(UWB)fiber-THz-fiber seamlessly converged real-time architecture, which utilizes the commercially mature digital coherent optical module to realize ultrahigh-capacity THz real-time wireless communication, is proposed in this study.(1) The proposed architecture employs the dual-polarization photonic up-conversion technique for THz generation and hybrid optoelectronic down-conversion technique for THz reception to facilitate the seamless integration between optical fiber and THz communications.(2) Because of the limited bandwidth of optoelectronic devices, multidimensional modulation techniques are adopted for UWB THz signals to improve spectral efficiency and transmission capacity.(3) An intelligent nonlinear joint compensation technique based on the deep neural network, which can effectively improve the signal-to-noise ratio of the time-varying hybrid fiber-THz-fiber channel, is proposed. Based on the investigations of the aforementioned key techniques, we, for the first time, realize the photonics-assisted record-high 100/200 Gb E real-time THz wireless transmission at 360–430 GHz band, the capacity of which is 10–20 times higher than that of *** proposed fiber-THz-fiber architecture can realize the smooth conversion between high-speed THz and lightwave signals. Moreover, the architecture can significantly reduce the research difficulty and development cost, thereby considerably accelerating the commercialization of 6G THz technology by thoroughly reusing commercial digital coherent optical module(DCO) modules, which are compatible with the physical layer transmission protocols, such as IEEE 802.3 and ITU-T G.798. Finally, this study also introduces some potential directions of

关键词： 6G THz wireless communication optical fiber communication seamlessly converged architecture real-time communication

Dual-services generation using an integrated polarization multiplexing modulator

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Chinese Optics Letters 2020年第11期18卷 27-31页

作者： Feng Zhao jianjun yu Jingling Li School of Electronic Engineering Xi’an University of Posts and TelecommunicationsXi'an 710121China

We proposed and demonstrated a new scheme for simultaneous generation of independent wired and wireless signals employing an integrated polarization multiplexing modulator. In the experimental system, a 10 Gb/s wired signal is imposed on the original optical carrier with one polarization, while a wireless signal with a bit rate larger than 4 Gb/s is carried on the generated millimeter wave of 76.44 GHz, which has polarization orthogonal to the wired signal. The dual services are successfully delivered over a 15 km standard single mode fiber;the power penalties of the wired and wireless signals are around 0.4 d B and 1.5 dB, respectively.

关键词： millimeter wave dual-parallel Mach-Zehnder modulator radio-over-fiber

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军用危险品铁路运输的问题与对策

国防交通工程与技术 2024年第4期22卷 1-3页

作者：孟晓山于建军亢玮冬高小涛桑满仙晋西防务装备研究院山西太原030027

军用危险品的铁路运输特点为运量大、运距远,受气候影响较小,在我国国防和军事运输领域中占据着重要地位。随着国防现代化建设的不断推进,对军用危险品铁路运输的安全和效率提出了更高的要求。深入剖析当前我国军用危险品铁路运输存在... 详细信息

军用危险品的铁路运输特点为运量大、运距远,受气候影响较小,在我国国防和军事运输领域中占据着重要地位。随着国防现代化建设的不断推进,对军用危险品铁路运输的安全和效率提出了更高的要求。深入剖析当前我国军用危险品铁路运输存在的一些问题,针对性提出了提高铁路运输性的对策,旨在提高军用危险品铁路运输的安全性、可靠性和快捷性,对于后续军用危险品铁路运输的发展具有指导意义。

关键词：军用危险品铁路运输智能化发展

An efficient and universal protoplast-based transient gene expression system for genome editing in Brassica crops

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Horticultural Plant Journal 2024年第4期10卷 983-994页

作者： Xiaoxiao yu Jintai yu Yin Lu Wenjing Li Guanzhong Huo Jun Zhang Yan Li jianjun Zhao Jun Li State Key Laboratory of North China Crop Improvement and Regulation College of Life SciencesHebei Agricultural UniversityBaodingHebei 071001China Hebei Key Laboratory of Plant Physiology and Molecular Pathology Hebei Agricultural UniversityBaodingHebei 071001China Key Laboratory of Vegetable Germplasm Innovation and Utilization of Hebei Collaborative Innovation Center of Vegetable Industry in HebeiCollege of HorticultureHebei Agricultural UniversityBaodingHebei 071001China College of Modern Science and Technology Hebei Agricultural UniversityBaodingHebei 071001China Human Resource Department Hebei Agricultural UniversityBaodingHebei 071001China

Protoplast-based transient gene expression system has been widely used in plant genome editing because of its simple operation and less *** order to establish a universal protoplast-based transient transfection system for verifying activities of genome editing vectors containing targets in Brassica,we systematically optimized factors affecting protoplast isolation and transient gene *** established an efficient protoplast-based transient gene expression system(PTGE)in Chinese cabbage,achieving high protoplast yield of 4.9×10^(5)·g^(-1)FW,viability over 95%,and transfection efficiency of 76%.We showed for the first time that pretreatment of protoplasts with a hypotonic MMG could significantly enhance the transfection ***,protoplasts incubated at 37℃ for 6 min improved the transfection efficiency to 86%.We also demonstrated that PTGE worked well(more than 50%transfection efficiency)in multiple Brassica species including cabbage,Pak Choi,Chinese kale,and ***,PTGE was used for validating the activities of CRISPR/Cas9 vectors containing targets in Chinese cabbage,cabbage,and pak choi,demonstrating the broad applicability of the established PTGE for genome editing in Brassica crops.

关键词： Chinese cabbage PTGE Transfection efficiency CRISPR/Cas9

应用颅内动脉瘤辅助评估软件评价未破裂动脉瘤稳定性的多中心前瞻性研究

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中华神经外科杂志 2024年第7期40卷 652-658页

作者：张福峻晖黄骥良米热扎提·吐尔洪刘健李天晓段传志李聪慧于建军吴鑫杨新健张鸿祺首都医科大学北京市神经外科研究所北京100070 首都医科大学附属北京天坛医院神经外科学中心北京100070 河南省人民医院神经外科郑州450003 南方医科大学珠江医院神经外科广州510280 河北医科大学第一附属医院神经外科石家庄050030 临沂市人民医院神经外科临沂276002 烟台毓璜顶医院神经外科烟台264009 首都医科大学宣武医院神经外科北京100053

目的探讨应用颅内动脉瘤辅助评估软件评价未破裂动脉瘤(UIA)稳定性的效果。方法前瞻性纳入2022年5—9月于首都医科大学附属北京天坛医院等7家中心神经外科就诊的UIA患者。分别采用软件辅助医生评估、医生独立评估、专家组评估、PHASES... 详细信息

目的探讨应用颅内动脉瘤辅助评估软件评价未破裂动脉瘤(UIA)稳定性的效果。方法前瞻性纳入2022年5—9月于首都医科大学附属北京天坛医院等7家中心神经外科就诊的UIA患者。分别采用软件辅助医生评估、医生独立评估、专家组评估、PHASES评分和ELAPSS评分标准评价所有患者的UIA是否稳定。使用分层随机抽样法将患者随机分为A、B两组,A组先由软件辅助医生评估,在4周洗脱期后再由医生独立评估;B组评估顺序相反。将专家组评估结果作为判断UIA稳定性的"金标准",比较动脉瘤辅助评估软件与其他评估方式的准确率、灵敏度、特异度及其与"金标准"的一致性,并根据动脉瘤最大径进行亚组分析。结果共纳入192例患者(227个动脉瘤),其中男62例,女130例;年龄[M(Q1,Q3)]为58.0(50.5,65.0)岁。专家组评估结果显示,227个动脉瘤中,稳定动脉瘤98个,不稳定动脉瘤129个。软件辅助医生评估的准确率和灵敏度(92.5%和93.8%)均高于医生独立评估(76.7%和85.3%)、PHASES评分(62.6%和39.5%)和ELAPSS评分(79.3%和76.7%)评估,差异均具有统计学意义(均P0.05),但高于医生独立评估(65.3%,P0.05),其中软件辅助医生评估与"金标准"的一致性最好;而PHASES评分与"金标准"评估结果的差异具有统计学意义(配对χ^(2)=45.84,P5~7 mm组中,软件辅助医生评估与"金标准"的一致性均较好(Kappa分别为0.94、0.79和0.85),且均高于其他评估方法。软件辅助医生评估和医生独立评估A组与B组的准确率的差异均无统计学意义(均P>0.05)。结论颅内动脉瘤辅助评估软件可以辅助神经外科医生进行UIA的稳定性评估,其准确率优于医生独立评估、PHASES评分和ELAPSS评分标准的评估结果,值得临床推广应用。

关键词：颅内动脉瘤人工智能稳定性评估诊断,计算机辅助