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Long-term evolution and gravitational wave radiation of neutron stars with differential rotation induced by r-modes

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Research in Astronomy and Astrophysics 2009年第9期9卷 1024-1034页

作者： yun-Wei yu xiao-feng Cao xiao-Ping Zheng Institute of Astrophysics Huazhong Normal University Wuhan 430079 China

In a second-order r-mode theory, Sa and Tome found that the r-mode oscillation in neutron stars （NSs） could induce stellar differential rotation, which naturally leads to a saturated state of the oscillation. Based on a consideration of the coupling of the r-modes and the stellar spin and thermal evolution, we carefully investigate the influences of the differential rotation on the long-term evolution of isolated NSs and NSs in low-mass X-ray binaries, where the viscous damping of the r-modes and its resultant effects are taken into account. The numerical results show that, for both kinds of NSs, the differential rotation can significantly prolong the duration of the r-modes. As a result, the stars can keep nearly a constant temperature and constant angular velocity for over a thousand years. Moreover, the persistent radiation of a quasi-monochromatic gravitational wave would also be predicted due to the long-term steady r-mode oscillation and stellar rotation. This increases the detectability of gravitational waves from both young isolated and old accreting NSs.

关键词： stars: neutron -- stars: evolution -- stars: rotation -- gravitational waves

Reliability evaluation of wireless sensor networks using an enhanced OBDD algorithm

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The Journal of China Universities of Posts and Telecommunications 2009年第5期16卷 62-70页

作者： xiao yu-feng CHEN Shan-zhi LI Xin LI yu-hong State Key Laboratory of Networking and Switching Beijing University of Posts and Telecommunications Beijing 100876 China State Key Laboratory of Wireless Mobile Communication China Academy of Telecommunications Technology Beijing 100083 China Information Engineering School Southwest University of Science and Technology Mianyang 621000 China

An enhanced ordered binary decision diagram （EOBDD） algorithm is proposed to evaluate the reliability of wireless sensor networks （WSNs）, based on the considerations of the common cause failure （CCF） and a large number of nodes in WSNs. The EOBDD algorithm analyzes the common cause event （CCE） and the network structure when CCE takes place according to the stochastic graph and the CCF model of WSNs. After constructing the ordered binary decision diagram （OBDD） of the original network with node expansion, it uses a set of OBDD variables （SOV） to guide reliability computations along this OBDD. The two steps about OBDD can decrease the cost of OBDD constructions and storage. Furthermore, the efficient OBDD structure and Hash tables can greatly decrease redundant computations of isomorphs. The experiment results show that the EOBDD can be used to evaluate the reliability of WSN efficiently.

关键词： network reliability ordered binary decision diagram wireless sensor networks common cause failure common cause event

Thermal hydraulic and mechanical analysis of CH HCSB TBM

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核聚变与等离子体物理 2006年第3期26卷 181-185页

作者： WANG xiao-yu feng Kai-ming ZHANG Guo-shu yuAN Tao Southwestern Institute of Physics Chengdu 610041

Based on the structure design and results of neutronics analysis of the CH HCSB TBM (Chinese helium cooled solid breeder test blanket module), thermal hydraulic and mechanical analyses have been carried out. Results s... 详细信息

关键词：热水力分析中子物理学分析再生区热核反应

Certain sulfonylurea drugs increase serum free fatty acid in diabetic patients:A systematic review and meta-analysis

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World Journal of Clinical Cases 2022年第26期10卷 9524-9535页

作者： Ming yu xiao-yu feng Shuai Yao Chang Wang Ping Yang Department of Cardiology China-Japan Union Hospital of Jilin UniversityJilin Provincial Cardiovascular Research InstituteJilin Provincial Engineering Laboratory for Endothelial Function and Genetic Diagnosis of Cardiovascular DiseaseChangchun 130031Jilin ProvinceChina Department of Endocrinology Jilin Guowen HospitalChangchun 130021Jilin ProvinceChina Department of Neurology China-Japan Union Hospital of Jilin UniversityChangchun 130031Jilin ProvinceChina

BACKGROUND Sulfonylurea(SU)is a commonly used antidiabetic drugs effective for type 2diabetes *** studies have reported that the SU treatment could alter the serum free fatty acid(FFA)concentration in diabetic patients;however,their exact effects remain *** To assess the impact of SU on the FFA level in diabetic *** A systematic literature search was conducted by consulting the PubMed,EMBASE,Cochrane Library,Reference Citation Analysis(https://***/),and Web of Science databases from January 1,1991 to July 30,*** a fixed-effects model or random-effects model was applied to study the association between SU treatment and FFA concentration according to the heterogeneity *** investigators independently performed data *** mean difference(MD)and corresponding 95%confidence interval(CI)were used to measure effect size.R3.5.1 software was utilized for conducting statistical *** A total of 13 studies with 2273 individuals were *** indicated that FFA concentration increased slightly after treatment with SU(MD=0.08,95%CI:0.03-0.12,P<0.01).In addition,we found that SU treatment combined with other antidiabetics could also increase the concentration of serum FFA(MD=0.14,95%CI:0.01-0.28,P<0.01).Regarding the type of SU,there was no significant difference in FFA concentration with glimepiride or *** concentration was higher at≥12 wk(MD=0.09,95%CI:0.04-0.13)but not at<12 wk(MD=0.01,95%CI:-0.07-0.09).CONCLUSION SU treatment could increase the serum FFA concentration in diabetic *** fundamental underlying mechanism still needs further investigation.

关键词： Sulfonylurea Free fatty acid Cardiovascular disease Diabetes mellitus Systematic review Meta-analysis

Prospects of elafibranor in treating alcohol-associated liver diseases

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World Journal of Gastroenterology 2025年第2期31卷 132-137页

作者： Wei-Tong Cui Hua-Ru Xue Dian-Fang Wei xiao-yu feng Kai Wang School of Basic Medicine Qilu Medical UniversityZibo 255300Shandong ProvinceChina School of Medical Imaging Qilu Medical UniversityZibo 255300Shandong ProvinceChina

Alcohol-related liver disease(ALD),which is induced by excessive alcohol con-sumption,is a leading cause of liver-related morbidity and *** pa-tients exhibit a spectrum of liver injuries,including hepatic steatosis,inflam-mation,and fibrosis,similar to symptoms of nonalcohol-associated liver diseases such as primary biliary cholangitis,metabolic dysfunction-associated steatotic liver disease,and nonalcoholic *** has been approved for the treatment of primary biliary cholangitis and has been shown to improve symptoms in both animal models and in vitro cell models of metabolic dysfunc-tion-associated steatotic liver disease and nonalcoholic ***,the efficacy of elafibranor in treating ALD remains *** this article,we comment on the recent publication by Koizumi et al that evaluated the effects of elafibranor on liver fibrosis and gut barrier function in an ALD mouse *** findings indicate the potential of elafibranor for ALD treatment,but further experimental investigations and clinical trials are warranted.

关键词： Elafibranor Alcohol-associated liver diseases Peroxisome proliferator-activated receptor Lipid Apoptosis Steatosis Inflammation Fibrosis

Substructure Prediction from Infrared Spectra by Using Support Vector Machines

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Chinese Chemical Letters 2005年第10期16卷 1354-1356页

作者： Jun Hong LIU Min Chun LU Fu Sheng NIE xiao yu feng Meng Long LI College of Chemistry Sichuan University Chengdu 610064

The potential of support vector machines （SVMs） for the substructure elucidation of infrared spectra have been investigated. The trained SVMs can identify the 16 substructures with high accuracy.

关键词： Infrared spectra substructures support vector machines.

Synergistic Cu single-atoms and clusters on tubular carbon nitride for efficient photocatalytic performances

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Rare Metals 2024年第11期43卷 5891-5904页

作者： yu-xiao feng Hui-Jun yu Tian-Guang Lu Zi-Ye Zheng Shuang Tian Li Xiang Shan Zhao Shu-Guang Wang Zuo-Li He Shandong Key Laboratory of Water Pollution Control and Resource Reuse School of Environmental Science and EngineeringShandong UniversityQingdao 266237China Weihai Research Institute of Industrial Technology of Shandong University Shandong UniversityWeihai 264209China School of Electrical Engineering Shandong UniversityJinan 250061China CEDAR Knight Cancer InstituteSchool of MedicineOregon Health and Science UniversityPortland 97201USA

Metal clusters or even single-atoms dispersed and anchored on the photocatalysts'surface can enhance photocatalytic performances on organic pollutant ***,a simple photoreduction method was used to create atomically dispersed metal single-atoms/clusters(MSCs,M=Cu,Pd,Au and Ag)on P-modulated tubular carbon nitride(TCN).The obtained MSCs@TCN demonstrated excellent photocatalytic performances for the degradation of sulfamethazine(SMZ).In particular,the photocatalyst with 2 wt%Cu loading showed ultrahigh SMZ oxidation efficiency(k=0.06110 min^(-1)),almost three times that of TCN(k=0.02066 min^(-1)).It also shows excellent stability in the 5th-cycle *** improved photocatalytic activity of the CuSCs@TCN is ascribed to the synergistic promotion of photogenerated charge separation by Cu single-atoms/clusters as active sites,accelerated charge transfer from bulk TCN to Cu sites through Cu-N_(x)***,the active sites of Cu single-atoms/clusters could promote the production of·O_(2)^(-),which participates in organic oxidation with strong oxidizing holes(h^(+)).This strategy paves a new avenue for designing high-performance photocatalysts decorated with metal single-atoms and clusters.

关键词： Carbon nitride Photocatalysis Cu single-atom Sulfamethazine Degradation

Antidiabetic effect of a novel non-thiazolidinedione PPAR γ/α agonist on ob/ob mice

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Acta Pharmacologica Sinica 2006年第10期27卷 1346-1352页

作者： Xi HU Ying feng yu SHEN xiao-feng ZHAO Juan-hong yu yu-she YANG Ying LENG~2 Shanghai Institute of Materia Medica,Shanghai Institute for Biological Sciences,Chinese Academy of Sciences,Shanghai 201203,China Shanghai Institute of Materia Medica Shanghai Institute for Biological Sciences Chinese Academy of Sciences Shanghai China

Aim:To study whether T33,a new synthesized non-thiazolidinedione(TZD)per-oxisome proliferator-activated receptor(PPAR)γ/α dual agonist has an antidia-betic effect on ob/ob ***:Ob/ob mice were treated with 4 mg/kg or 8mg/kg T33 by gavage for 20 *** glucose levels were measured *** glucose tolerance test(OGTT)and an insulin tolerance test(ITT)were pre-formed on d 8 and d 12,*** levels of insulin,triglyceride and freefatty acid(FFA)in the serum were measured at the end of *** and liver triglyceride content was also ***:T33reduced the hyperglycemia,hyperinsulinemia and hyperlipidemia of the ob/*** OGTT and ITT showed that the insulin resistance state of the ob/obmice was obviously ameliorated after T33 *** 20 d treatment with 8mg/kg T33,the triglyceride content in the gastrocnemius muscle decreasedsignificantly.T33 did not have any effect on triglyceride content in the liver,whereas rosiglitazone significantly increased the hepatocyte lipid ***:The PPARγ/α dual agonist T33 has antidiabetic and insulin-sensitiz-ing effects in ob/ob *** has the potential to be a new therapeutic candidate forthe treatment of type 2 diabetes.

关键词： diabetes insulin-sensitizing peroxisome proliferator-activated receptors thiazolidinediones

Reversal of isoproterenol-induced downregulation of phospholamban and FKBP12.6 by CPU0213-mediated antagonism of endothelin receptors

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Acta Pharmacologica Sinica 2007年第11期28卷 1746-1754页

作者： yu feng,xiao-yun TANG,De-zai DAI~2,Yin DAIResearch Division of Pharmacology,China Pharmaceutical University,Nanjing 210009,China Research Division of Pharmacology China Pharmaceutical University Nanjing China

Aim:The downregutation of phospholamban (PLB) and FKBP12.6 as a result of β-receptor activation is involved in the pathway(s) of congestive heart *** that the endothelin (ET)-1 system may link to downregulated PLBand ***:Rats were subjected to ischemia/reperfusion (I/R) tocause heart failure (HF).1 mg/kg isoproterenol (ISO) was injected subcutane-ously (sc) for 10 d to worsen HF.30 mg/kg CPU0213 (sc),a dual ET receptor.(ETAR/ETBR) antagonist was given from d 6 to d *** d 11,cardiac function wasassessed together with the determination of mRNA levels of ryanodine receptor 2,calstabin-2 (FKBP12.6),PLB,and sarcoplasmic reticulum Ca2+-*** rat ventricular myocytes were incubated with ISO at 1×10-6mol/L to set up anin vitro model of *** (PRO),CPU0213,and darusentan (DAR,anETAR antagonist) were incubated with cardiomyocytes at 1×10-5mol/L or 1×10-6mol/L in the presence of ISO (1×10-6mol/L).Immunocytochemistry and Westernblotting were applied for measuring the protein levels of PLB and ***:The worsened hemodynamics produced by I/R were exacerbated by *** significant downregulation of the gene expression of PLB andFKBP12.6 and worsened cardiac function by ISO were reversed by *** ISO 1×10-6mol/L produced a sharp decline of PLB and FKBP12.6 proteinsrelative to the *** downregulation of the protein expression was signifi-cantly reversed by the ET receptor antagonist CPU0213 or DAR,comparable tothat achieved by ***:This study demonstrates a role of ET inmediating the downregulation of the cardiac Ca2+-handling protein by ISO.

关键词： heart failure endothelin receptor antagonists phospholamban FKBP12.6 propranolol CPU0213