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表面活性剂和全氟三丁胺对可移植海藻酸钠/聚赖氨酸/海藻酸钠微胶囊性能的影响

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中国组织工程研究与临床康复 2008年第27期12卷 5271-5274页

作者：王喆王为于炜婷吕国军谢红国林军章李晓霞马小军中国科学院大连化学物理研究所生物医用材料工程组辽宁省大连市116023

实验以球磨法测定海藻酸钠/聚赖氨酸/海藻酸钠微胶囊的破碎率,并用激光共聚焦扫描显微镜观察绿色荧光标记的蛋白是否进入微胶囊,考察了加入表面活性剂F68和全氟三丁胺对不同直径微胶囊的机械强度、免疫隔离性能和通透性能的影响。通过... 详细信息

实验以球磨法测定海藻酸钠/聚赖氨酸/海藻酸钠微胶囊的破碎率,并用激光共聚焦扫描显微镜观察绿色荧光标记的蛋白是否进入微胶囊,考察了加入表面活性剂F68和全氟三丁胺对不同直径微胶囊的机械强度、免疫隔离性能和通透性能的影响。通过对不同直径的海藻酸钠/聚赖氨酸/海藻酸钠微胶囊的破碎率的分析,基本确定了添加F68及全氟三丁胺的浓度对不同粒径微囊的机械强度产生了不同的协同影响。控制F68和全氟三丁胺的浓度配比及减小微囊的直径可以减小F68和全氟三丁胺对海藻酸钠/聚赖氨酸/海藻酸钠微胶囊的机械强度的影响。而表面活性剂和全氟三丁胺的加入基本不影响微胶囊的免疫隔离性能和通透性能。

关键词：全氟三丁胺 APA微胶囊破碎率机械强度免疫隔离性能通透性能生物材料

Targeting TrkB–PSD-95 coupling to mitigate neurological disorders

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Neural Regeneration Research 2025年第3期20卷 715-724页

作者： Xin Yang yu-Wen Alvin Huang John Marshall Department of Molecular Biology Cell Biology and BiochemistryBrown UniversityProvidenceRIUSA Department of Neurology Warren Alpert Medical School of Brown UniversityProvidenceRIUSA Center for Translational Neuroscience Robert J.and Nancy D.Carney Institute for Brain Science and Brown Institute for Translational ScienceBrown UniversityProvidenceRIUSA

Tropomyosin receptor kinase B(TrkB)signaling plays a pivotal role in dendritic growth and dendritic spine formation to promote learning and *** activity-dependent release of brain-derived neurotrophic factor at synapses binds to pre-or postsynaptic TrkB resulting in the strengthening of synapses,reflected by long-term ***,the association of postsynaptic density protein-95 with TrkB enhances phospholipase Cγ-Ca^(2+)/calmodulin-dependent protein kinaseⅡand phosphatidylinositol 3-kinase-mechanistic target of rapamycin signaling required for long-term *** this review,we discuss TrkB-postsynaptic density protein-95 coupling as a promising strategy to magnify brain-derived neurotrophic factor signaling towards the development of novel therapeutics for specific neurological disorders.A reduction of TrkB signaling has been observed in neurodegenerative disorders,such as Alzheimer's disease and Huntington's disease,and enhancement of postsynaptic density protein-95 association with TrkB signaling could mitigate the observed deficiency of neuronal connectivity in schizophrenia and *** with brain-derived neurotrophic factor is problematic,due to poor pharmacokinetics,low brain penetration,and side effects resulting from activation of the p75 neurotrophin receptor or the truncated TrkB.T1 *** TrkB agonists and antibodies that activate TrkB are being intensively investigated,they cannot distinguish the multiple human TrkB splicing isoforms or cell type-specific *** TrkB–postsynaptic density protein-95 coupling provides an alternative approach to specifically boost TrkB signaling at localized synaptic sites versus global stimulation that risks many adverse side effects.

关键词： Angelman syndrome autism brain-derived neurotrophic factor depression neurodegenerative disorder neurodevelopmental disorder postsynaptic density protein-95 synaptic plasticity TrkB

Correlation between the rock mass properties and maximum horizontal stress:A case study of overcoring stress measurements

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 39-48页

作者： Peng Li Meifeng Cai Shengjun Miao yuan Li yu Wang Key Laboratory of Ministry of Education for Efficient Mining and Safety of Metal Mines University of Science and Technology BeijingBeijing 100083China State Key Laboratory of Coal Resources and Safe Mining China University of Mining and TechnologyXuzhou 221116China

Understanding the mechanical properties of the lithologies is crucial to accurately determine the horizontal stress *** investigate the correlation between the rock mass properties and maximum horizontal stress,the three-dimensional(3D)stress tensors at 89 measuring points determined using an improved overcoring technique in nine mines in China were adopted,a newly defined characteristic parameter C_(ERP)was proposed as an indicator for evaluating the structural properties of rock masses,and a fuzzy relation matrix was established using the information distribution *** results indicate that both the vertical stress and horizontal stress exhibit a good linear growth relationship with *** is no remarkable correlation between the elastic modulus,Poisson's ratio and depth,and the distribution of data points is scattered and ***,there is no obvious relationship between the rock quality designation(RQD)and *** maximum horizontal stress σ_(H) is a function of rock properties,showing a certain linear relationship with the C_(ERP)at the same *** addition,the overall change trend of σ_(H) determined by the established fuzzy identification method is to increase with the increase of C_(ERP).The fuzzy identification method also demonstrates a relatively detailed local relationship betweenσ_H and C_(ERP),and the predicted curve rises in a fluctuating way,which is in accord well with the measured stress data.

关键词： overcoring stress measurements elastic modulus Poisson's ratio rock quality designation maximum horizontal stress fuzzy identification

大豆(石享)化物的研究Ⅰ.大豆粗磷脂中γ-麦胚(石享)之层析分离

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化学学报 1956年第4期 288-291页

作者：丁宏勛汪猷丁维钰黄耀曾中国科学院有机化学研究所

用氧化铝柱層析自大豆粗磷脂所得的混合(石享)能简便地分离得纯粹的y-麥胚(石享)。

关键词：旋光率所得大豆磷脂三氯甲烷氯仿氯代烃

Nanostructured ZnO/BiVO_(4)I-scheme heterojunctions for piezocatalytic degradation of organic dyes via harvesting ultrasonic vibration energy

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 488-497页

作者： Yiling Li Xiaoyao yu Yingjie Zhou Yao Lin Ying Wu Key Laboratory of the Ministry of Education for Advanced Catalysis Materials College of Chemistry and Materials ScienceZhejiang Normal UniversityJinhua 321004China

BiVO_(4)porous spheres modified by ZnO were designed and synthesized using a facile two-step *** resulting ZnO/BiVO_(4)composite catalysts have shown remarkable efficiency as piezoelectric catalysts for degrading Rhodamine B(RhB)unde mechanical vibrations,they exhibit superior activity compared to pure *** 40wt%ZnO/BiVO_(4)heterojunction composite displayed the highest activity,along with good stability and *** enhanced piezoelectric catalytic activity can be attributed to the form ation of an I-scheme heterojunction structure,which can effectively inhibit the electron-hole ***,hole(h+)and superoxide radical(·O_(2)^(-))are proved to be the primary active ***,ZnO/BiVO_(4)stands as an efficient and stable piezoelectric catalyst with broad potential application in the field of environmental water pollution treatment.

关键词： piezoelectric catalytic heterojunction dye degradation ultrasonic vibration

林麝雌体粪便甲状腺激素的测定及其生物学意义

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北京林业大学学报 2016年第5期38卷 108-113页

作者：魏雨婷周冉刘宝庆胡晓龙刘树强李林海胡德夫北京林业大学自然保护区学院陕西片仔癀麝业有限责任公司北京市国家林业局林产工业规划设计院

林麝饲养繁育承担着重建野生种群和保障麝香可持续利用的艰巨任务,然而其饲养种群长期受到健康状态不稳定和疾病高发的困扰,同时,受到濒危等级和试验样品的限制,迄今鲜有涉及林麝生理参数的文献。本研究于2014年7—8月分别采集陕西火烧... 详细信息

林麝饲养繁育承担着重建野生种群和保障麝香可持续利用的艰巨任务,然而其饲养种群长期受到健康状态不稳定和疾病高发的困扰,同时,受到濒危等级和试验样品的限制,迄今鲜有涉及林麝生理参数的文献。本研究于2014年7—8月分别采集陕西火烧店和四川米亚罗林麝饲养场的林麝粪样,采用酶联免疫法(ELISA)测定雌麝粪便中三碘甲腺原氨酸(T3)的含量,以探讨雌麝粪便T3值表达的生理状态及变化趋势。结果表明,陕西火烧店和四川米亚罗饲养场雌麝粪便T3在所研究的时段内不存在显著差异;两地雌麝粪便T3在3岁至5岁期间随着年龄的增长呈现逐渐上升的趋势,但在5岁之后随着年龄的增大而逐渐下降,这可能意味着雌麝在5岁左右达到生理盛期;雌麝粪便T3的聚类结果发现,不同年龄组均存在差异显著的3个类型,即生理代谢的低、中、高类型。利用粪便T3从能量代谢角度揭示雌麝的生理特性,可能有助于麝繁育群的组建、饲养管理及健康评判。

关键词：林麝粪便甲状腺激素生理状态指示作用

Advancement of technology towards high-performance non-aqueous aluminum-ion batteries

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Journal of Energy Chemistry 2021年第6期30卷 169-188,I0005页

作者： ting-ting wei Panpan Peng Si-yu Qi Yan-Rong Zhu ting-Feng Yi School of Materials Science and Engineering Northeastern UniversityShenyang 110819LiaoningChina School of Resources and Materials Northeastern University at QinhuangdaoQinhuangdao 066004HebeiChina Key Laboratory of Dielectric and Electrolyte Functional Material Hebei Province Qinhuangdao 066004HebeiChina

Al-ion batteries(AIBs) have been identified as one of the most hopeful energy storage systems after Li-ion batteries on account for the ultrahigh volumetric capacity,high safety and low cost from the rich abundance of ***,some inevitable shortcomings,such as the formation of passive oxide film,hydrogen side reactions and anode corrosion,finally limit the large-scale application of aqueous *** nonaqueous AIBs have been considered as one of most hopeful alternatives for high-powered electrochemical energy storage ***,various technical and scientific obstacles should be resolved because nonaqueous AIBs are still *** significant efforts have aimed to resolve these issues towards large-scale applications,and some important advancement has been *** the present review,we mainly intended to offer an overview of non-aqueous AIBs systems,and we comprehensively reviewed the recent research advancement of the cathode materials,anode materials electrolyte and collectors as well as the fundamental understanding of the functional *** addition,we have also analyzed several technical challenges and summarized the strategies used for overcoming the challenges in improving the electrochemical properties,including morphology control,surface engineering,doping and construction of composite electrodes as well as the charge storage mechanisms of the materials with different crystal *** last,future research orientation and development prospect of the AIBs are proposed.

关键词： Al-ion batteries Electrode Electrolyte Collector Electrochemical performance

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四川省地热资源分布及特征简析

四川地质学报 2016年第2期36卷 239-242页

作者：倪高倩韦玉婷屈泽伟胡亚召四川省地质工程勘察院成都610000

四川省作为全国地热资源丰富的省市之一,其地热资源的开发利用具有较大的潜力。根据四川省内地貌条件差异,结合已发现的300多处温泉、地热井进行分析,按热水形成的地质作用、所赋存的地质构造条件和介质特征,将四川省地热资源分为两大... 详细信息

四川省作为全国地热资源丰富的省市之一,其地热资源的开发利用具有较大的潜力。根据四川省内地貌条件差异,结合已发现的300多处温泉、地热井进行分析,按热水形成的地质作用、所赋存的地质构造条件和介质特征,将四川省地热资源分为两大类型四个资源区和三种热储类型,归纳各个类型地热资源的特点,为四川省地热资源未来因地制宜的开发利用规划提供参考。

关键词：地热资源分类特征四川

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四川地热流体水文地球化学及同位素特征简析

新能源进展 2016年第3期34卷 184-194页

作者：倪高倩张恒韦玉婷胡亚召四川省地质工程勘察院成都610000

四川省范围内有沉积盆地型和隆起山地型两类地热资源,共划分五个地热区。从五个区采取的205组水样的水文地球化学特征及184组~2H、^(18)O和61组^(14)C特征分析显示,四川省各地热区地热流体基本来自于大气降水补给,地热流体的水文地球化... 详细信息

四川省范围内有沉积盆地型和隆起山地型两类地热资源,共划分五个地热区。从五个区采取的205组水样的水文地球化学特征及184组~2H、^(18)O和61组^(14)C特征分析显示,四川省各地热区地热流体基本来自于大气降水补给,地热流体的水文地球化学和同位素特征与其所属的热储类型和热储开放性有关。盆地型热储主要为岩溶层状热储,山地型热储主要是变质岩为主的裂隙带状热储和层状带状复合型热储。盆地型热储开放性较山地型弱,地热流体矿化度和理疗元素含量均比山地型高,易形成深埋藏的卤水,地下水平均径流时间较山地型长。本研究可为四川省地热资源未来的开发利用规划提供参考。

关键词：四川地热流体沉积盆地型地热资源隆起山地型地热资源水文地球化学特征同位素