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世界临床病例杂志 2023年第24期11卷 5823-5829页

作者： Tao Wang Yi-yu shen Graduate School Zhejiang Chinese Medical UniversityHangzhou 310053Zhejiang ProvinceChina Department of Hepatobiliary Surgery The Second Affiliated Hospital of Jiaxing UniversityJiaxing 314051Zhejiang ProvinceChina

BACKGROUND This is the first report of an ROS1-CENPW fusion gene in pancreatic *** SUMMARY A 77-year-old woman with a pancreatic tumor and multiple liver metastases was admitted to our *** testing revealed the presence of the ROS1-CENPW fusion gene,a rare fusion gene that has not been previously reported in the field of pancreatic *** patient received crizotinib plus AG(albumin paclitaxel plus gemcitabine)*** treatment,the patient’s condition stabilized,and her prognosis was *** The ROS1-CENPW gene treatment regimen used in this case is an excellent treatment option that provides new hope for patients with advanced pancreatic cancer and similar genetic *** date,owing to the rarity of the ROS1-CENPW fusion gene,our team has encountered only a single ***,the efficacy of crizotinib plus AG chemotherapy in patients with pancreatic acinar cell carcinoma harboring the ROS1-CENPW fusion gene requires further validation.

关键词： ROS1-CENPW Pancreatic acinar cell carcinoma Crizotinib Gemcitabine Albumin paclitaxel Case report

我国新生儿早期基本保健技术实施进展的范围综述

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中国妇幼卫生杂志 2024年第1期15卷 59-66页

作者：俞春兰顾春怡刘洪妍沈瑜复旦大学附属妇产科医院上海200011 复旦大学护理学院上海200032

目的系统分析新生儿早期基本保健技术在我国的开展现状,为临床实践及研究提供参考。方法根据范围综述的研究方法,系统检索2013年1月1日至2022年12月31日中国知网、万方数据知识服务平台、中文科技期刊数据库、中国生物医学文献数据库、P... 详细信息

目的系统分析新生儿早期基本保健技术在我国的开展现状,为临床实践及研究提供参考。方法根据范围综述的研究方法,系统检索2013年1月1日至2022年12月31日中国知网、万方数据知识服务平台、中文科技期刊数据库、中国生物医学文献数据库、PubMed、Ovid-Embase、CINAHL等国内外数据库中关于我国新生儿早期基本保健技术实施进展的相关文献,对纳入的文献进行筛选、汇总和分析。结果共纳入文献50篇,其中随机对照研究22篇、类实验研究23篇、质性研究2篇、病例对照研究1篇、队列研究1篇、混合性研究1篇。相关研究开展地区涉及我国19个省、直辖市和自治区,东、中、西部地区分别占33.3%、12.3%和54.4%。开展研究的机构数量涉及78所医院。37篇文献(74.0%)的研究对象为阴道分娩的足月新生儿及其母亲,而涉及剖宫产、早产儿及其母亲的文献仅13篇(26.0%)。新生儿相关结局包括喂养情况、新生儿相关并发症、生命体征、生长发育、行为状态、脐部情况、住院率、生化指标、死亡率、智力发育10项指标。随访时间介于新生儿出生后42 d至6月龄。母亲相关结局包括产后情绪体验、泌乳情况、产后出血、产后恢复指标、生化指标、分娩情况6项指标。结论近年来,我国新生儿早期基本保健技术的实施评价成为研究热点,纳入文献在研究对象、核心措施、母婴健康结局随访等方面尚存在一定局限,有必要进一步推进新生儿早期基本保健技术在我国不同地区的规范开展,并持续评价其对母婴健康状况的近远期影响。

关键词：婴儿护理婴儿新生儿范围综述

复元活血汤联合石氏伤科正骨夹板治疗桡骨远端骨折的临床疗效

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检验医学与临床 2024年第5期21卷 628-634,639页

作者：申钰郑春伟曹贺周瑾上海市杨浦区中医医院中医骨伤科上海200080

目的探究复元活血汤联合石氏伤科正骨夹板治疗桡骨远端骨折患者的临床疗效。方法收集2021年1月至2023年1月在该院被诊断为桡骨远端骨折的120例患者进行前瞻性研究,依据随机数字表法将其分为治疗组和对照组,每组60例。采用酶联免疫吸... 详细信息

目的探究复元活血汤联合石氏伤科正骨夹板治疗桡骨远端骨折患者的临床疗效。方法收集2021年1月至2023年1月在该院被诊断为桡骨远端骨折的120例患者进行前瞻性研究,依据随机数字表法将其分为治疗组和对照组,每组60例。采用酶联免疫吸附试验(ELISA)检测两组患者血清碱性磷酸酶(ALP)、骨保护素(OPG)、骨钙素(BGP)水平;检测两组患者血液流变学指标;测定两组患者视觉模拟评分法(VAS)评分与肿胀评分,并对腕关节、掌指关节活动度、Cooney腕关节功能及X射线评分进行评定。结果整复后,治疗组患者血清ALP、BGP、OPG水平高于对照组,血浆黏度、红细胞刚性指数、红细胞聚集指数、全血黏度低于对照组,差异均有统计学意义(P<0.05)。两组患者整复前后的VAS评分存在组间、时间效应(P_(组间)=0.027、P_(时间)<0.001)。两组患者整复前后肿胀评分、Cooney评分、背伸角度、掌屈角度、X射线评分均存在时间、组间、交互效应(P_(时间)<0.05、P_(组间)<0.05、P_(交互)<0.05)。对照组不同时间肿胀评分比较结果为整复后2周和整复后4周的肿胀评分低于整复前和整复后即刻(P<0.05),整复后8周肿胀评分低于整复前、整复后即刻和整复后2周(P<0.05)。治疗组不同时间肿胀评分比较结果为整复后8周<整复后4周<整复后2周<整复后即刻和整复前(P<0.05),治疗组整复后4周、整复后8周的肿胀评分低于对照组(F=3.990、8.522,P<0.05)。对照组和治疗组不同时间Cooney评分、背伸角度比较结果为整复前<整复后即刻<整复后2周<整复后4周<整复后8周(P<0.05)。治疗组和对照组不同时间掌屈角度、X射线评分比较结果为整复前及整复后即刻<整复后2周<整复后4周<整复后8周(P<0.05)。整复后2周、4周及8周治疗组患者Cooney评分高于对照组(F=8.758、2.293、3.873,P<0.05)。整复后8周治疗组患者背伸角度、掌屈角度、X射线评分大于对照组(F=3.475、2.042、19.010,P<0.05)。结论复元活血汤联合石氏伤科正骨夹板对于桡骨远端骨折患者的疗效良好,并在手臂功能的改善上具有一定积极效用。

关键词：复元活血汤石氏伤科正骨夹板桡骨远端骨折手臂功能血液流变学

Synthesis and Surface Activity of Novel Triazole-based Cationic Gemini Surfactants

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Chinese Chemical Letters 2003年第6期14卷 653-656页

作者： Ling Guang QIU An Jian XIE yu Hua shen School of Chemistry and Chemical Engineering Anhui UniversityHefei 230039 Institute of Solid State Physics Chinese Academy of SciencesHefei 230031

The synthesis and surfactant activities of two new cationic gemini surfactants containing triazole compound as spacer were described. Their critical micelle concentrations (CMC), which are 1.8×10-4 mol/L and 3.9×10-4 mol/L respectively, are much lower than that of conventional surfactant cetyltrimethyl ammonium chloride (CTAC). In addition, compared with some gemini surfactants containing phenylene, xylylene and stilbenyl as spacer, this new kind of surfactants has good solubility in water at room temperature because of containing more hydrophilic groups or atoms in molecules.

关键词： Gemini surfactant cationic surfactant critical micelle concentration triazole synthesis.

Modified two-grid method for solving coupled Navier-Stokes/Darcy model based on Newton iteration

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Applied Mathematics(A Journal of Chinese Universities) 2015年第2期30卷 127-140页

作者： shen yu-jing HAN Dan-fu SHAO Xin-ping Department of Mathematics Zhejiang University Department of Mathematics Hangzhou Normal University School of Science Hangzhou Dianzi University

A new decoupled two-gird algorithm with the Newton iteration is proposed for solving the coupled Navier-Stokes/Darcy model which describes a fluid flow filtrating through porous media. Moreover the error estimate is given, which shows that the same order of accuracy can be achieved as solving the system directly in the fine mesh when h = H2. Both theoretical analysis and numerical experiments illustrate the efficiency of the algorithm for solving the coupled problem.

关键词： Navier-Stokes equation Darcy's law interface coupling two-grid algorithm Newton iteration

模拟牲畜采食对高寒草甸土壤潜在氧化亚氮排放的影响

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草地学报 2024年第9期32卷 2794-2802页

作者：吴晓芬陈有超蒋文婷沈玉叶蔡延江浙江农林大学省部共建亚热带森林培育国家重点实验室浙江杭州311300 浙江农林大学环境与资源学院/碳中和学院浙江杭州311300

探明牲畜采食对土壤氧化亚氮(N_(2)O)排放的影响,是准确预测放牧干扰下高寒草甸生态系统温室气体变化的关键。本研究通过刈割留茬模拟牲畜不同强度采食行为(无采食,CK;轻度采食,LD:留茬高度3 cm;重度采食,HD:留茬高度<1 cm),利用室内培... 详细信息

探明牲畜采食对土壤氧化亚氮(N_(2)O)排放的影响,是准确预测放牧干扰下高寒草甸生态系统温室气体变化的关键。本研究通过刈割留茬模拟牲畜不同强度采食行为(无采食,CK;轻度采食,LD:留茬高度3 cm;重度采食,HD:留茬高度<1 cm),利用室内培养法测定土壤潜在N_(2)O排放,并测定了土壤理化性质、酶活性以及硝化和反硝化功能基因丰度等指标。结果表明:LD处理对土壤潜在N_(2)O排放无显著影响,但HD处理显著降低了潜在N_(2)O排放(P<0.05)。重度采食导致输入土壤铵态氮(NH+4-N)和碳减少,降低土壤AOA-amoA,nirS和nosZI基因丰度及反硝化潜势(Denitrification potential,DP),减弱土壤硝化和反硝化作用从而降低N_(2)O排放。综上,轻度采食对土壤潜在N_(2)O排放无显著影响,但重度采食可能通过降低土壤硝化和反硝化作用,减弱土壤潜在N_(2)O排放。

关键词：高寒草甸硝化作用反硝化作用放牧

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Microwave-assisted conversion of biomass wastes to pseudocapacitive mesoporous carbon for high-performance supercapacitor

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Journal of Energy Chemistry 2019年第12期28卷 1-7页

作者： Xiangkun Bo Kun Xiang yu Zhang yu shen Shanyong Chen Yongzheng Wang Mingjiang Xie Xuefeng Guo Key Lab of Mesoscopic Chemistry MOE School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023JiangsuChina Hubei Key Laboratory for Processing and Application of Catalytic Materials Huanggang Normal UniversityHuanggang 438000HubeiChina

Developing an efficient approach of transforming biomass waste to functional carbon-based electrode materials applied in supercapacitor offers an important and high value-added practical application due to the abundance and considerable low price of biomass ***,a hierarchical carbon functionalized with electrochemical-active oxygen-containing groups was fabricated by microwave treatment from the biomass waste of camellia *** obtained mesoporous carbon(MAC)owns nanosheet morphology,rich mesoporosity,large surface area(1726 m2/g)and very high oxygenic functionalities(16.2 wt%)with pseudocapacitive *** electrode of supercapacitor and tested in 2.0 M H2 SO4,the MAC exhibits an obvious pseudocapacitive activity and achieved a superior supercapacitive performance to that of directly activated carbon(DAC-800)including high specific capacitance(367 F/g vs.298 F/g)and better rate performance(66%vs.44%).The symmetrical supercapacitor based on MAC shows a high capacity of275 F/g,large energy density of 9.55 Wh/kg(at power density of 478 W/kg)and excellent cycling stability with 99%capacitance retention after 10000 continuous charge-discharge,endowing the obtained MAC a promising functional material for electrochemical energy storage.

关键词： Microwave conversion Mesoporous carbon Pseudocapacitive activity Supercapacitor

A MnOOH-Polyaniline Nanocomposite Modified Gold Electrode for Electrochemical Sensing of Nitrite

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Chinese Journal of Chemistry 2017年第8期35卷 1317-1321页

作者： yu shen Jian Zhang Qinglin sheng Jianbin Zheng Institute of Analytical Science Shaanxi Provincial Key Laboratory of Electroanalytical Chemistry Northwest University Xi'an Shaanxi 710069 China

A novel non-enzymatic nitrite sensor was fabricated by immobilizing MnOOH-PANI nanocomposites on a gold electrode （Au electrode）. The morphology and composition of the nanocomposites were investigated by transmission electron microscopy （TEM） and Fourier transform infrared spectrum （FTIR）. The electrochemical results showed that the sensor possessed excellent electrocatalytic ability for NO2 oxidation. The sensor displayed a linear range from 3.0 μmol·L^-1 to 76.0 mmol·L^-1 with a detection limit of 0.9 μmol·L^-1 （S/N=3）, a sensitivity of 132.2 μA·L·mol^-1·cm^-2 and a response time of 3 s. Furthermore, the sensor showed good reproducibility and long-term stability. It is expected that the MnOOH-PANI nanocomposites could be applied for more active sensors and used in practice for nitrite sensing.

关键词： electrochemical sensor nanocomposites polyaniline MnOOH nitrite

Breakdown Behavior of Eutectic Carbide in High Speed Steel During Hot Compression

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Journal of Iron and Steel Research International 2011年第1期18卷 41-48页

作者： ZHOU Bin shen yu CHEN Jun CUI Zhen-shan National Engineering Research Center of Die and Mold CAD Shanghai Jiao Tong University Shanghai 200030 China

The evolution of euteelie carbide in as CaSl M2 high speed steeL was invesligated with hot compression test and metallographic examination. Initial rodlike or irregular eutectic carbides were broken into smaller particles during hot deformation by thermomechanical disintegration, while diffusion controlled phase transformation was not remarkable. Combining with numerical simulation, the relationship between breakdown ratio of carbide network and deformation parameters was obtained. Strain was the most important driving force to shatter euteclic carbides and disperse products. Furthermore, critical strain values were obtained, beyond which carbide network disappeared, and fractured carbides kept a stable profile and they were deformed with matrix coordinately. A higher temperature or lower strain rate resulted in a lower crilical strain.

关键词： hol compression high speed steel eulectic earbidc breakdown mechanism

Distributed optimization for discrete-time multiagent systems with nonconvex control input constraints and switching topologies

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Chinese Physics B 2021年第12期30卷 283-290页

作者： Xiao-yu shen Shuai Su Hai-Liang Hou School of Automation Central South UniversityChangsha 410083China National Engineering Research Center of Rail Transportation Operation and Control System Beijing Jiaotong UniversityBeijing 100044China State Key Laboratory of Rail Traffic Control and Safety Beijing Jiaotong UniversityBeijing 100044China

This paper addresses the distributed optimization problem of discrete-time multiagent systems with nonconvex control input constraints and switching *** introduce a novel distributed optimization algorithm with a switching mechanism to guarantee that all agents eventually converge to an optimal solution point,while their control inputs are constrained in their own nonconvex *** is worth noting that the mechanism is performed to tackle the coexistence of the nonconvex constraint operator and the optimization gradient *** on the dynamic transformation technique,the original nonlinear dynamic system is transformed into an equivalent one with a nonlinear error *** utilizing the nonnegative matrix theory,it is shown that the optimization problem can be solved when the union of switching communication graphs is jointly strongly ***,a numerical simulation example is used to demonstrate the acquired theoretical results.

关键词： multiagent systems nonconvex input constraints switching topologies distributed optimization