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Chinese Journal of Chemical Engineering 2024年第10期74卷 44-51页

作者： qingbo yu Xianhua Li Qingping Wang The First Affiliated Hospital of Anhui University of Science and Technology(Huainan First People's Hospital) Anhui University of Science and TechnologyHuainan 232001China Anhui Industrial Generic Technology Research Center for New Materials from Coal-based Solid Wastes Huainan 232001China School of Materials Science and Engineering Anhui University of Science and TechnologyHuainan 232001China

In order to find the optimal combination method of secondary utilization of fly ash and graphite-phase carbon nitride(g-C_(3)N_(4))modification,an efficient composite photocatalyst of γ-Al_(2)O_(3)/g-C_(3)N_(4)was obtained by calcining the composite precursors of Al(OH)3/dicyandiamide(DCDA).The introduction of Al(OH)_(3)prepared by combining fly ash into the precursors causes hydrogen-bonding interactions between Al(OH)_(3)and DCDA,which facilitate the removal of N atoms from the edges of the CN framework of g-C_(3)N_(4)during condensation,and the composites prepared possess more cyano *** addition,γ-Al_(2)O_(3)and g-C_(3)N_(4)form a chemical bond at the interface,and this chemical bonding causes the density of the electron cloud in the vicinity of the N atoms to *** them,the strongest chemical bonding between Al_(2)O_(3)and g-C_(3)N_(4)was observed in ACN-1,whereas the most cyanine defects were formed in ACN-1,which made ACN-1 exhibit the best photocatalytic degradation of methylene blue,which is 2.48 times higher than that of the pristine g-C_(3)N_(4).

关键词： Precursors g-C_(3)N_(4) Waste treatment Catalyst Synthesis

miR-192-5p靶向CKIP-1促进骨质疏松患者骨髓间充质干细胞成骨分化

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中国组织工程研究 2025年第13期29卷 2641-2647页

作者：鄂正康辛红伟于清波张允帅开封市中心医院(河南大学附属人民医院)骨六科河南省开封市475000

背景:酪蛋白激酶2结合蛋白1(casein kinase 2-interaction protein-1,CKIP-1)是一种重要的骨形成负调控基因,其敲除鼠骨质显著增强、骨形成和骨密度也显著提高。而miRNA作为较早发现的小分子调控物,对大多数编码基因具有调控作用,在成... 详细信息

背景:酪蛋白激酶2结合蛋白1(casein kinase 2-interaction protein-1,CKIP-1)是一种重要的骨形成负调控基因,其敲除鼠骨质显著增强、骨形成和骨密度也显著提高。而miRNA作为较早发现的小分子调控物,对大多数编码基因具有调控作用,在成骨分化中发挥重要作用。目的:探讨miRNA/CKIP-1对骨质疏松患者骨髓间充质干细胞成骨分化的影响及其分子机制。方法:采用miRNA-Seq技术检测2022年3-6月在开封市中心医院骨外科就诊32例骨质疏松患者及同期体检中心健康人群骨髓间充质干细胞中miRNA的变化情况;利用Targetscan网站预测靶向调控CKIP-1的miRNA,利用荧光素酶报告基因实验检测miRNA与CKIP-1启动子区DNA的结合;在骨髓间充质干细胞中转染miR-192-5p类似物(miR-192-5p mimics)/阴性对照(NC mimics)或miR-192-5p抑制剂(miR-192-5p inhibitor)/阴性对照(NC inhibitor),成骨诱导后第7,14天,通过实时荧光定量PCR技术及茜素红染色检测成骨标志基因Runt相关转录因子2(Runx2)、骨钙素、抗骨桥蛋白、骨唾液蛋白及CKIP-1的表达水平和骨髓间充质干细胞向成骨细胞分化的情况;采用蛋白质免疫印迹实验及茜素红染色检测miR-192-5p/CKIP-1/轴对细胞成骨分化的的调控作用。结果与结论:与健康组相比,骨质疏松组有16个miRNA表达明显升高,53个miRNA表达明显降低(P<0.05);利用Targetscan网站预测,并通过荧光素酶报告基因实验验证,发现miR-192-5p与CKIP-1有互补的核苷酸序列(P<0.05);过表达miR-192-5p,Runx2、骨钙素、骨桥素和骨唾液蛋白的表达水平显著升高(P<0.05),抑制miR-192-5p,Runx2、骨钙素、骨桥素和骨唾液蛋白的表达水平显著降低(P<0.05),而沉默CKIP-1的表达后,Runx2、骨钙素及骨桥素的蛋白水平增加(P<0.05),逆转了敲低miR-192-5p对细胞成骨分化的抑制作用。上述结果证实,miR-192-5p在骨质疏松症中表达降低;miR-192-5p通过靶向抑制CKIP-1的表达,促进骨髓间充质干细胞成骨分化。

关键词：骨质疏松微小RNA miR-192-5p 酪蛋白激酶2结合蛋白1 骨髓间充质干细胞成骨分化 Runt相关转录因子2 骨唾液蛋白

Trans-scale study on the thermal response and initiation of ternary fluoropolymer-matrix reactive materials under shock loading

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Defence Technology（防务技术） 2023年第3期21卷 184-195页

作者： Chao Ge Die Hu Jin Wang qingbo yu Haifu Wang yuanfeng Zheng School of Mechatronical Engineering Beijing Institute of TechnologyBeijing100081China

To investigate the thermal response and initiation behavior of ternary fluoropolymer-matrix PTFE/Al/W reactive materials,a research combining shock loading tests and trans-scale modelling is *** the basis of a good agreement of the numerically simulated and tested shock wave propagation,the significant impact of component ratios and particle sizes on the evolution of mesoscopic temperature,hot-spots and initiation is well characterized and *** demonstrate that as the content of W increases,the range of mesoscopic high-temperature area increases and tends to distribute more uniform,while material with smaller W particles causes more intense particle deformation and larger temperature *** time to reach the critical temperature shows positive correlation to the content of W,while the critical temperature of hot-spots shows negative correlation to the particle size of *** PTFE/Al/W of high density,with the increase of W particle size,the reaction rate decrease,however the time to reach the peak reaction rate shortens.

关键词： deformation shock loading

Enhanced damage mechanism of reinforced concrete targets impacted by reactive PELE: An analytical model and experimental validation

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Defence Technology（防务技术） 2024年第12期42卷 12-30页

作者： Jiahao Zhang Mengmeng Guo Sheng Zhou Chao Ge Pengwan Chen qingbo yu China State Key Laboratory of Explosion Science and Safety Protection Beijing Institute of TechnologyBeijing100081China

Compared with PELE with inert fillings such as polyethylene and nylon,reactive PELE(RPELE)shows excellent damage effects when impacting concrete targets due to the filling deflagration *** present work,an analytical model describing the jacket deformation and concrete target damage impacted by RPELE was presented,in which the radial rarefaction and filling deflagration reaction were *** impact tests of RPELE on concrete target in the 592-1012 m/s were carried out to verify the analytical *** on the analytical model,the angle-length evolution mechanism of the jacket bending-curling deformation was revealed,and the concrete target damage was further *** can find out that the average prediction errors of the front crater,opening and back crater are 6.8%,8.5%and 7.1%,***,the effects of radial rarefaction and deflagration were *** was found that the neglect of radial rarefaction overestimates the jacket deformation and concrete target damage,while the deflagration reaction of filling increases the diameter of the front crater,opening and back crater by 25.4%,24.3%and 31.1%,*** research provides a valuable reference for understanding and predicting the jacket deformation and concrete target damage impacted by RPELE.

关键词： Reactive PELE Concrete target Jacket deformation Radial rarefaction Enhanced damage mechanism

Prediction of anther-expressed gene regulation in Arabidopsis

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Chinese Science Bulletin 2008年第20期53卷 3198-3203页

作者： HUANG JiFeng YANG JingJin WANG Guan yu qingbo YANG ZhongNan Mathematics & Science College Shanghai Normal University Shanghai 200234 China College of Life and Environmental Sciences Shanghai Normal University ShangHai 200234 China

Anther development in Arabidopsis, a popular model plant for plant biology and genetics, is controlled by a complex gene network. Despite the extensive use of this genus for genetic research, little is known about its regulatory network. In this paper, the direct transcriptional regulatory relationships between genes expressed in Arabidopsis anther development were predicted with an integrated bioinformatic method that combines mining of microarray data with promoter analysis. A total of 7710 transcription factor-gene pairs were obtained. The 80 direct regulatory relationships demonstrating the highest confidence were screened from the initial 7710 pairs; three of the 80 were validated by previous experiments. The results indicate that our predicted results were reliable. The regulatory relationships revealed by this research and described in this paper may facilitate further investigation of the molecular mechanisms of anther development. The bioinformatic method used in this work can also be applied to the prediction of gene regulatory relationships in other organisms.

关键词：植物生长发育花粉囊基因调节生物信息学

Short-Term Wind Power Prediction Method Based on Combination of Meteorological Features and CatBoost

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Wuhan University Journal of Natural Sciences 2023年第2期28卷 169-176页

作者： MOU Xingyu CHEN Hui ZHANG Xinjing XU Xin yu qingbo LI yunfeng Jilin Province Meteorological Information Network Center Changchun 130062JilinChina

As one of the hot topics in the field of new energy,short-term wind power prediction research should pay attention to the impact of meteorological characteristics on wind power while improving the prediction ***,a short-term wind power prediction method based on the combination of meteorological features and Cat Boost is ***,morgan-stone algebras and sure independence screening(MS-SIS)method is designed to filter the meteorological features,and the influence of the meteorological features on the wind power is ***,a sort enhancement algorithm is designed to increase the accuracy and calculation efficiency of the method and reduce the prediction risk of a single ***,a prediction method based on Cat Boost network is constructed to further realize short-term wind power *** National Renewable Energy Laboratory(NREL)dataset is used for experimental *** results show that the short-term wind power prediction method based on the combination of meteorological features and Cat Boost not only improve the prediction accuracy of short-term wind power,but also have higher calculation efficiency.

关键词： meteorological features short-term power load forecasting Cat Boost wind power

AtMYB103 is a crucial regulator of several pathways affecting Arabidopsis anther development

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Science China(Life Sciences) 2010年第9期53卷 1112-1122页

作者： ZHU Jun ZHANG GuoQiang CHANG yuHua LI XiaoChuan YANG Jun HUANG XueYong yu qingbo CHEN Hui WU TianLong YANG ZhongNan College of Agriculture and Biotechnology Shanghai Jiao Tong UniversityShanghai 200240China College of Life and Environmental Sciences Shanghai Normal UniversityShanghai 200234China Shanghai Institute of Plant Physiology and Ecology Chinese Academy of SciencesShanghai 200032China

Previous reports indicated that AtMYB103 has an important role in tapetum development,callose dissolution,and exine formation in *** ***,we further characterized its function in anther development by expression pattern analysis,transmission electron microscopy observation of the knockout mutant,and microarray analysis of downstream genes.A total of 818 genes differentially expressed between ms188 and the wild-type were identified by global expression profiling *** classification showed that loss-of-function of AtMYB103 impairs cell wall modification,lipid metabolic pathways,and signal transduction throughout anther *** in situ hybridization confirmed that transcription factors acting downstream of AtMYB103 (At1g06280 and At1g02040) were expressed in the tapetum and microspores at later stages,suggesting that they might have important roles in *** results indicated that AtMYB103 is a crucial regulator of Arabidopsis anther development.

关键词： Arabidopsis AtMYB103 tapetum development transcription factor microarray

Hydrogen production via steam reforming of bio-oil model compounds over supported nickel catalysts

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Journal of Energy Chemistry 2015年第3期24卷 299-308页

作者： Huaqing Xie qingbo yu Xin Yao Wenjun Duan Zongliang Zuo Qin Qin School of Materials and Metallurgy Northeastern University

The steam reforming of four bio-oil model compounds（acetic acid,ethanol,acetone and phenol） was investigated over Ni-based catalysts supported on Al2O3 modified by Mg,Ce or Co in this *** activation process can improve the catalytic activity with the change of high-valence Ni（Ni2O3,NiO） to low-valence Ni（Ni,NiO）.Among these catalysts after activation,the Ce-Ni/Co catalyst showed the best catalytic activity for the steam reforming of all the four model *** long-term experiment at 700°C and the S/C ratio of 9,the Ce-Ni/Co catalyst still maintained excellent stability for the steam reforming of the simulated bio-oil（mixed by the four compounds with the equal masses）.With CaO calcinated from calcium acetate as CO2 sorbent,the catalytic steam reforming experiment combined with continuous in situ CO2 adsorption was *** the comparison of the case without the adding of CO2 sorbent,the hydrogen concentration was dramatically improved from 74.8% to 92.3%,with the CO2 concentration obviously decreased from 19.90% to 1.88%.

关键词： hydrogen production bio-oil model compounds Ni catalyst CO2capture

多边形铁素体的体积分数和大小对管线钢落锤撕裂性能的影响

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机械工程学报 2011年第24期47卷 44-49,56页

作者：于庆波孙莹 yu Hailiang 刘相华徐州工程学院机电工程学院徐州221008 东北大学研究院沈阳110189 伍伦贡大学机电与材料学院伍伦贡2522澳大利亚

在天然气管线脆性断裂止裂的研究中,由于落锤撕裂试验(Drop weight tear test,DWTT)采用了全板厚试样,其试验状态接近管道在实际情况下的应力应变状态,能充分显示管材断裂的真实状况及其止裂能力,所以,DWTT已经成为评价管线钢脆性断裂... 详细信息

在天然气管线脆性断裂止裂的研究中,由于落锤撕裂试验(Drop weight tear test,DWTT)采用了全板厚试样,其试验状态接近管道在实际情况下的应力应变状态,能充分显示管材断裂的真实状况及其止裂能力,所以,DWTT已经成为评价管线钢脆性断裂止裂能力的重要方法,并以试样的断口纤维率(Shear-area percentage,SA)大小作为衡量标准。在不同的工业生产条件下轧制X70管线钢,并对它们进行落锤撕裂试验、疲劳试验、拉伸试验及冲击试验,探讨X70管线钢显微组织中多边形铁素体体积分数和大小对DWTT断口纤维率的影响。研究结果表明,当多边形铁素体作为第二相存在时,断口纤维率随着多边形铁素体体积分数的增加呈现出先上升后下降的特点;当多边形铁素体作为主要基体组织存在时,断口纤维率主要受多边形铁素体晶粒大小的影响,并且晶粒越细断口纤维率越高。

关键词：脆性断裂管线钢断口纤维率落锤撕裂试验

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M/A岛对粒状贝氏体钢冲击韧性的影响

热加工工艺 2012年第24期41卷 41-42页

作者：于庆波徐州工程学院江苏省大型工程装备检测与控制重点建设实验室江苏徐州221008

钢的成分、冷却速度及终冷温度等因素会影响M/A岛形貌和分布。通过力学性能检验和显微组织观察,研究了M/A岛形貌及分布状态对钢的冲击韧性的影响。结果表明:终冷温度是决定M/A岛颗粒大小的重要工艺;细小的M/A岛对粒状贝氏体钢韧性的降... 详细信息

钢的成分、冷却速度及终冷温度等因素会影响M/A岛形貌和分布。通过力学性能检验和显微组织观察,研究了M/A岛形貌及分布状态对钢的冲击韧性的影响。结果表明:终冷温度是决定M/A岛颗粒大小的重要工艺;细小的M/A岛对粒状贝氏体钢韧性的降低不明显;粗大的M/A岛能降低粒状贝氏体钢的冲击韧性。

关键词： M A岛粒状贝氏体冲击韧性