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Journal of Cosmetics, Dermatological Sciences and Applications 2016年第5期6卷 199-209页

作者： Gallant k. L. Chan kevin Q. Wu Zack C. F. Wong Aster H. Y. Fung Xuyan Lin Lucy J. Lou Tina T. Dong karl W. k. Tsim Division of Life Science and Center for Chinese Medicine R & D The Hong Kong University of Science and Technology Hong Kong China

Skin lightening and tanning are two major areas dominating the market of skincare and cosmetic products. Though the demands are originated from two different communities, the two areas share a same goal—skin colour tuning. The known safe compounds with skin colour tuning activities are limited. In contrary, Chinese medicinal herb provides a pool of natural bioactive compounds, which have been used in Asian countries for long time and have been tested for its toxicity. Here, we demonstrate a high throughput screening platform for potential compounds usable for skin colour tuning. From 147 natural compounds, 26 of them showed potential in skin tanning functions by using the high throughput melanogenesis platform based on the melanogenesis assay on B16 melanocytes. Five of them promoted melanogenesis by over 50%. Moreover, apart from 1, 8-dihydroxyanthraquinone, the other four compounds showed enhancement effect on tyrosinase activity. From the result, the compounds increased the Vmax of tyrosinase without changing the km in a dose-dependent manner. Thus, there should be no irreversible structural change of the enzyme. Definitely, this report contributes to the development of personalization in skincare and cosmetic products.

关键词： Skin Lightening Skin Tanning High-Throughput Platform Melanogenesis Personalization Skincare and Cosmetic Products

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光伏储能电站不同储能形式经济性对比分析

电力科技与环保 2024年第3期40卷 276-285页

作者：康渭滨寇明鑫张文文俞福友张建鹏山丹县综能智慧新能源有限公司甘肃张掖734000

新能源电站配备储能是能源发展的重要趋势,储能电站可以平抑新能源出力的波动,提高能源利用率和电网安全性。为比较不同类型的储能电站与光伏电站联合运营的经济效益,针对储能电站建立了电量模型、经济模型和成本模型,并以甘肃某10万kW... 详细信息

新能源电站配备储能是能源发展的重要趋势,储能电站可以平抑新能源出力的波动,提高能源利用率和电网安全性。为比较不同类型的储能电站与光伏电站联合运营的经济效益,针对储能电站建立了电量模型、经济模型和成本模型,并以甘肃某10万kW光伏电站项目为研究对象,研究了光伏电站配备不同储能形式的经济性和控制策略。采用了一种基于距离的k-means聚类分析法来合并相似场景提炼原始数据,比较了单独配备磷酸铁锂电池储能、单独配备压缩空气储能以及压缩空气与磷酸铁锂电池耦合储能3种配置方式的经济性。结果显示:单独配置磷酸铁锂电池储能经济性最高,投资回收期为7.16 a;压缩空气与磷酸铁锂电池耦合储能的经济性次之,投资回收期为8.93 a;单独配置压缩空气储能的经济性最低,投资回收期为9.03 a。

关键词：压缩空气储能磷酸铁锂电池光伏电站经济性分析

New anti-pulmonary fibrosis prenylflavonoid glycosides from Epimedium koreanuin

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Chinese Journal of Natural Medicines 2022年第3期20卷 221-228页

作者： ZHAO yu-Dan ZHANG Xin YANG Wan-yue ZHANG Rui-Qi MU Lin-Tong HAN Ling LV Chong-Ning LU Jin-Cai School of Traditional Chinese Materia Medica Shenyang Pharmaceutical UniversityShenyang 110016China Liaoning Provincial key Laboratory of TCM Resources Conservation and Development Shenyang Pharmaceutical UniversityShenyang 110016China NERCfor the Pharmaceutics of Traditional Chinese Medicines Benxi 117004China

Four new prenylflavonoid glycosides,namely koreanoside H-k(1-4),together with eleven known ones(5-15)were isolated from the leaves of Epimedium koreanum *** structures were elucidated by ID NMR,2D NMR,HR-ESI-MS,IR and *** identification of the sugar moieties was carried out by means of acid hydrolysis and HPLC analysis of their *** is worth noting that compound 3 and compound 4 were elucidated to contain fucose and quinovose moieties,which were two extremely rare sugar units from the genus *** anti-pulmonary fibrosis activity of the new compounds was evaluated using A549 cell *** 1,2 and 4 showed significant anti-pulmonary fibrosis activities.

关键词： Epimedium koreanum Prenylflavonoid glycoside Anti-pulmonary fibrosis

干制工艺对鲢鱼品质及晚期糖化终末产物含量的影响

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食品与机械 2022年第7期38卷 13-20页

作者：栾傲男王传洋 kevin Li 俞健王发祥刘永乐李向红李彦长沙理工大学食品与生物工程学院湖南长沙410114 湖南康宝莱蕾硕天然产物有限公司湖南长沙410100

目的:探究干制工艺对鲢鱼食用品质及安全的影响。方法:以新鲜鲢鱼为材料,以腌制盐添加量(NaCl)、腌制温度、腌制时间、风干温度和风干时间为考察因素,探究不同加工条件对鱼干复水率、色泽、质构以及AGEs形成的影响。结果:腌制盐添加量... 详细信息

目的:探究干制工艺对鲢鱼食用品质及安全的影响。方法:以新鲜鲢鱼为材料,以腌制盐添加量(NaCl)、腌制温度、腌制时间、风干温度和风干时间为考察因素,探究不同加工条件对鱼干复水率、色泽、质构以及AGEs形成的影响。结果:腌制盐添加量和风干温度对鱼干制品的感官评定影响显著(P<0.05),最佳加工工艺条件为腌制盐添加量9%,腌制温度4℃,腌制时间3 h,风干温度60℃,风干时间24 h。对鱼干风味贡献最大的为烷烃、芳香类化合物及含硫有机化合物,其中腌制盐添加量9%,腌制温度4℃,腌制时间3 h,风干温度60℃的鱼干制品的风味物质保留较好。鱼干制品色泽金黄,质地紧实,组织不松软。随着腌制盐添加量的增加,羧甲基赖氨酸(CML)和羧乙基赖氨酸(CEL)含量增加;但3%和9%腌制盐添加量下的鱼干的CML和CEL差别较小。结论:鲢鱼在不同干制工艺中所得品质与潜在危害物不同,在腌制盐添加量9%,腌制温度4℃,腌制时间3 h,风干温度60℃,风干时间24 h下所得的鱼干制品为最优产品。

关键词：鲢鱼风干晚期糖基化终末产物风味潜在危害物

The Expression of PI3k, AkT, β-Catenin and VEGFR2 in Medulloblastoma

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Journal of Biosciences and Medicines 2017年第3期5卷 32-38页

作者： Xiao Lin yu Li Department of Pathology Chongqing Medical University Chongqing China Chongqing key Laboratory of Neurobiology Chongqing Medical University Chongqing China Institute of Neuroscience Chongqing Medical University Chongqing China

Medulloblastoma (MB) is common tumor of the central nervous system in children. It’s reported that PI3k/AkT and Wnt signal pathway have important roles in MB. This study aims to investigate the expression of PI3k, AkT, Β-catenin and VEGFR-2 in MB to find a new pathway for MB. A total of 33 MB and 17 control brain cases were retrospectively evaluate d for PI3k, AkT, β-catenin and VEGFR-2 expression by immunohistochemical staining, and the relationship with clinical feature were analyzed. The positive rate of PI3k, AkT, β-catenin and VEGFR-2 in 33 MB were significantly greater than those in control group

关键词： PI3k AkT β-Catenin VEGFR2 Medulloblastoma

Glass formation in Fe-Cr-Zr-B-Mo alloys by tuning Nb addition

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China Foundry 2021年第5期18卷 450-456页

作者： Cong-ran Fu Wei Zhang Qing-chun Xiang Ying-dong Qu Ying-lei Ren Bo yu ke-qiang Qiu School of Materials Science and Engineering Shenyang University of TechnologyShenyang 110870China Shenyang Research Institute of Foundry Co.Ltd. Shenyang 110022China

Fe-based bulk metallic glasses(BMGs)with high boron content have potential application as a coating material used in the framework for storing spent nuclear fuels to support their safe long-term *** high glass forming ability(GFA)and large supercooled liquid region are therefore required for such Fe-based BMGs in either the glassy powder fabrication or the subsequent coating *** order to meet these requirements,the influence of Nb content on the GFA of Fe_(57)Cr_(10)Zr_(8)B_(18)Mo_(7-x)Nb_(x)(x=1-5,at.%)alloys was investigated,as Nb has positive roles in GFA and thermal stability of *** results indicate that a fully amorphous phase in the as-cast samples with 3 mm in diameter is obtained for both the Fe_(57)Cr_(10)Zr_(8)B_(18)Mo_(5)Nb_(2) and Fe_(57)Cr_(10)Zr_(8)B_(18)Mo_(4)Nb_(3) *** corresponding supercooled liquid regions of the two BMGs are 78 k and 71 k,*** mechanism for improving their GFA was analyzed based on the principle of metal solidification,the parameters for glass formation and thermal properties of the *** compression strength and Vicker’s hardness of the two BMGs are 1,950 MPa and 1,310 HV,2,062 MPa and 1,180 HV,*** developed BMGs with high B content,good GFA,and very high hardness can be used as coating materials to the framework for spent nuclear fuels.

关键词： amorphous microstructure Nb glass-forming ability coating material

2016—2021年5—10月辽宁省降水量时空分布精细化特征分析

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气象与环境学报 2024年第4期40卷 54-63页

作者：李萍陈传雷陈宇牛丹刘硕聂安祺张绍勇中国气象局流域强降水重点开放实验室/暴雨监测预警湖北省重点实验室中国气象局武汉暴雨研究所湖北武汉4302051 辽宁省气象台辽宁沈阳110166 辽宁省气象灾害监测预警中心辽宁沈阳110166 辽宁省气象信息中心辽宁沈阳110166 辽宁省气象装备保障中心辽宁沈阳110166

选用2016—2021年5—10月辽宁省小时加密观测降水资料,分析辽宁省降水过程、短时强降水过程、极端短时强降水过程降水量时空分布特征,应用k均值聚类法对汛期短时强降水过程降水累积小时数的空间分布进行分类。结果表明:辽宁省短时强降... 详细信息

选用2016—2021年5—10月辽宁省小时加密观测降水资料,分析辽宁省降水过程、短时强降水过程、极端短时强降水过程降水量时空分布特征,应用k均值聚类法对汛期短时强降水过程降水累积小时数的空间分布进行分类。结果表明:辽宁省短时强降水过程(小时降水量大于或等于20 mm)和极端短时强降水过程(小时降水量大于或等于该站点历史降水量升序后的第99.9百分位)受地形影响较大。短时强降水高发区主要分布在辽宁东南部的沿海地区、辽宁西部的沿海平原和地势较高地区及辽宁东南部的迎风坡地区。辽宁省汛期降水受季风环流影响,有明显的季节变化,平均降水量和降水频次最大值发生在7月和8月,降水时段主要集中在午后至夜间。辽宁省短时强降水过程降水频次的区域间差异较大,极端短时强降水过程区域间差异较小。

关键词：累积小时数 k均值聚类短时强降水加密自动站

Improved interfacial property by small molecule ethanediamine for high performance inverted planar perovskite solar cells

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Journal of Energy Chemistry 2021年第3期30卷 467-474页

作者： Guodong Zhang yunxin Zhang Siqi Chen Hao Chen Le Liu Wenming Ding Jinhui Wang Anyu Zhang Shuping Pang Xin Guo Lianqing yu Tonggang Jiu School of Materials Science and Engineering China University of PetroleumQingdao 266580ShandongChina Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of SciencesQingdao 266101ShandongChina Dalian Institute of Chemical Physics Chinese Academy of SciencesDalian 116023LiaoningChina

We report a simple and effective method to realize desirable interfacial property for inverted planar perovskite solar cells(PSCs)by using small molecule ethanediamine for the construction of a novel polyelectrolyte hole transport material(P3CT-ED HTM).It is found that P3CT-ED can not only improve the hole transport property of P3CT-k but also improve the crystallinity of adjacent perovskite *** addition,the introduction of ethanediamine into P3CT realigns the conduction and valence bands upwards,passivates surface defects and reduces nonradiative *** a consequence,compared to P3CT-k hole transport layer(HTL)based devices,the average power conversion efficiency(PCE)is boosted from17.2% to 19.6% for the counterparts with P3CT-ED,with simultaneous enhancement in open circuit voltage and fill *** resultant device displays a champion PCE of 20.5% with negligible hysteresis.

关键词： Improved interfacial property Inverted planar perovskite solar cells Passivated trap states Crystallinity Ethanediamine

The origin of different morphology of internal oxide precipitates in ferritic and austenitic steels

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Journal of Materials Science & Technology 2023年第30期161卷 88-100页

作者： Zhao Shen Xiaoqin Zeng Shengchuan Wu Hongbing yu Benjamin M.Jenkins Phani karamched Michael P.Moody Jianqiang Zhang You Wang Sergio Lozano-Perez National Engineering Research Center of Light Alloy Net Forming and State key Laboratory of Metal Matrix Composites School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240China State key Laboratory of Traction Power Southwest Jiaotong UniversityChengdu 610031China Department of Engineering Science University of OxfordParks RoadOX13PJ OxfordUK Department of Materials University of OxfordParks RoadOX13PH OxfordUK School of Materials Science and Engineering University of New South WalesSydneyNSW 2052Australia School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China

The internal oxide precipitates were supposed to be spherical in Wagner’s original theory,while the fol-lowing research demonstrated that this assumption is an exception rather than the truth,which caused deviations in the application of this *** this study,the internal oxide precipitates have a needle-like and a near-spherical morphology in a Fe-9Cr ferritic and a Fe-17Cr-9Ni austenitic steels after expo-sure to 600℃ deaerated steam for 600 h,*** nano-to-atomic scale characterization shows that the morphology of the internal oxide precipitates is controlled by the structure of the interfaces be-tween the metal matrix and the internal oxide,while the interface structure is mainly affected by the crystallographic structure of the two phases and their orientation *** addition,the internal oxide precipitation-induced volume expansion and the outward Fe diffusion-induced volume shrink oc-cur simultaneously during the oxidation *** stress status in the internal oxidation zone(IOZ)is the competing result of the two factors,which could dynamically affect the high-temperature *** results obtained in this study suggest that there is potential to control the distribution,morphology,and interface structure of the internal oxide precipitates by selecting appropriate base metal and internal oxide-forming element,in order to obtain better high-temperature oxidation-resistant materials.

关键词： Austenitic steel Ferritic steel Oxide precipitates Phase boundary Orientation relationship

基于生态位理论与理想风水模式的梅山地区传统村落景观空间解析:以安化县马路溪村为例

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湖南城市学院学报（自然科学版） 2024年第1期33卷 31-39页

作者：张擎罗晨静陈成周小梅龙运涛余红兵刘敏湖南城市学院管理学院湖南益阳413000 数字化城乡空间规划关键技术湖南省重点实验室湖南益阳413000 湖南省城乡生态规划与修复工程技术研究中心湖南益阳413000

传统村落作为传统文化生态的活化石和博物馆,其研究保护意义重大。从文化和生态出发,运用传统风水理念和现代生态位理论对梅山地区马路溪村的景观空间结构、驱动因素、生态位扩充及空间结构演化进行了分析。结果表明:马路溪村整体景观... 详细信息

传统村落作为传统文化生态的活化石和博物馆,其研究保护意义重大。从文化和生态出发,运用传统风水理念和现代生态位理论对梅山地区马路溪村的景观空间结构、驱动因素、生态位扩充及空间结构演化进行了分析。结果表明:马路溪村整体景观空间结构为“盆地+豁口+走廊”的壶天模式;其综合了各生态要素,契合“藏风得水”的理想风水格局,构建了符合中国人心目中理想的“山—林—屋—水—林”的景观模式;马路溪村景观空间在不断发展演化的过程中出现了诸多问题。基于此,提出必须发展一种基于传统村落保护与再生的新生态观及构建可持续发展模式以修正演化过程中出现的问题,从而稳步实现马路溪村的生态位扩充和景观空间演变。

关键词：梅山地区传统村落生态位理论风水模式景观空间解析