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Microstructure and texture evolution of Cu-Cr-Co-Ti alloys during the two-stage cryorolling

Rare Metals 2024年第9期43卷 4535-4547页

作者： Jia-jun Zhang Long-Jian Li Zhi-feng Liu Zong-Ning Chen En-yu Guo Hui-jun Kang Ren-Geng Li Tong-Min Wang Key Laboratory of Solidification Control and Digital Preparation Technology(Liaoning Province) School of Materials Science and EngineeringDalian University of TechnologyDalian 116024China Center of Hyper-Gravity Experimental and Interdisciplinary Research Zhejiang UniversityHangzhou 310058China Ningbo Institute of Dalian University of Technology Ningbo 315000China Key Laboratory for Light-Weight Materials Nanjing Tech UniversityNanjing 210009China

This study entailed an investigation of the mechanical properties,microstructural and texture orientation evolutions of Cu-Cr-Co-Ti alloys prepared via twostage cryorolling and intermediate aging *** this end,X-ray diffraction and electron backscatter diffraction were *** results indicate that the two-stage cryorolling and intermediate aging treatments led to the development of profuse twin bundles and significantly enhanced the mechanical *** initial cryorolling led to coplanar slip and developed a strong Y({111})orientation,accelerating the formation of Goss({011})orientation and a Brass-type *** intermediate aging treatment relieved the restriction on dislocation slip and reoriented the grains toward the Copper({112})and Z({111})*** Z orientation,with a relatively high volume fraction,dominated the *** cryorolling intensified twinning and shear banding,transforming the Copper-type shear bands into Brass-type shear bands with rhomboidal prism *** areas inside the Brasstype shear bands exhibited a Y orientation,and the areas outside the shear bands exhibited a stable Brass-type *** evident decrease in the weighted Schmid factors demonstrated that the two-stage cryorolling and intermediate aging treatment can modify the texture evolution and aid the design of high-performance Cu alloys.

关键词： Copper alloys Two-stage cryorolling Macrotexture evolution Electron backscatter diffraction Schmid factor

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Spectral Fittings of Warm Coronal Radiation with High Seed Photon Temperature:Apparent Low-temperature and Flat Soft Excess in AGNs

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Research in Astronomy and Astrophysics 2024年第7期24卷 135-144页

作者： Ze-yuan Tang jun-Jie feng jun-Hui Fan School of Mathematics and Information Science Guangzhou UniversityGuangzhou 510006China Center for Astrophysics Guangzhou UniversityGuangzhou 510006China Astronomy Science and Technology Research Laboratory of Department of Education of Guangdong Province Guangzhou 510006China Key Laboratory for Astronomical Observation and Technology of Guangzhou Guangzhou 510006China

A warm corona has been widely proposed to explain the soft excess(SE)in X-ray above the 2-10 ke V power law extrapolation in Active Galactic Nuclei(AGNs).In actual spectral fittings,the warm coronal seed photon temperature(T_s)is usually assumed to be far away from the soft X-ray,but kT_scan reach close to 0.1 ke V in the standard accretion disk *** this study,we used Monte Carlo simulations to obtain radiation spectra from a slab-like warm corona and fitted the spectra using the spherical-geometry-based routine THCOMP or a thermal *** findings reveal tha high T_scan influence the fitting results.A moderately high kT_s(around 0.03 ke V)can result in an apparent low-temperature and flat SE,while an extremely high kT_s(around 0.07 ke V)can even produce an unobserved blackbody-like *** conclusions indicate that,for spectral fittings of the warm coronal radiation(SE in AGNs),kT_sshould be treated as a free parameter with an upper limit,and an accurate coronal geometry is necessary when kT_s>0.01 ke V.

关键词： galaxies active-accretion-accretion disks-black hole physics

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Hybrid pedestrian positioning system using wearable inertial sensors and ultrasonic ranging

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Defence Technology（防务技术） 2024年第3期33卷 327-338页

作者： Lin Qi yu Liu Chuanshun Gao Tao feng yue yu School of Communication and Information Engineering Chongqing University of Posts and TelecommunicationsChongqing 400065China Department of Land Surveying and Geo-Informatics The Hong Kong Polytechnic UniversityHong Kong 999077China

Pedestrian positioning system(PPS)using wearable inertial sensors has wide applications towards various emerging fields such as smart healthcare,emergency rescue,soldier positioning,*** performance of traditional PPS is limited by the cumulative error of inertial sensors,complex motion modes of pedestrians,and the low robustness of the multi-sensor collaboration *** paper presents a hybrid pedestrian positioning system using the combination of wearable inertial sensors and ultrasonic ranging(H-PPS).A robust two nodes integration structure is developed to adaptively combine the motion data acquired from the single waist-mounted and foot-mounted node,and enhanced by a novel ellipsoid constraint *** addition,a deep-learning-based walking speed estimator is proposed by considering all the motion features provided by different nodes,which effectively reduces the cumulative error originating from inertial ***,a comprehensive data and model dual-driven model is presented to effectively combine the motion data provided by different sensor nodes and walking speed estimator,and multi-level constraints are extracted to further improve the performance of the overall *** results indicate that the proposed H-PPS significantly improves the performance of the single PPS and outperforms existing algorithms in accuracy index under complex indoor scenarios.

关键词： Pedestrian positioning system Wearable inertial sensors Ultrasonic ranging Deep-learning Data and model dual-driven

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Chemoradiotherapy plus tislelizumab for mismatch repair proficient rectal cancer with supraclavicular lymph node metastasis:A case report

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2219-2224页

作者： Wen-Tao Zhong yuan Lv Qian-yu Wang Ran An Gang Chen jun-feng Du The Second School of Clinical Medicine Southern Medical UniversityGuangzhou 510515Guangdong ProvinceChina Department of General Surgery The 7^(th)Medical Center of PLA General HospitalBeijing 100700China Department of Pathology The 7^(th)Medical Center of PLA General HospitalBeijing 100700China

BACKGROUND According to the latest report,colorectal cancer is still one of the most prevalent cancers,with the third highest incidence and mortality *** of advanced rectal cancer with distant metastases is usually unsatisfactory,especially for mismatch repair proficient(pMMR)rectal cancer,which leads to poor prognosis and *** SUMMARY We report a case of a pMMR rectal adenocarcinoma with metastases of multiple lymph nodes,including the left supraclavicular lymph node,before treatment in a 70-year-old *** received full courses of chemoradiotherapy(CRT)followed by 4 cycles of programmed death 1 inhibitor Tislelizumab,and a pathologic complete response(pCR)was achieved,and the lesion of the left supraclavicular lymph node also *** pMMR advanced rectal cancer with preserved intact distant metastatic lymph nodes may benefit from full-course CRT combined with immunotherapy.

关键词： Rectal cancer Metastasis Chemoradiotherapy Immunotherapy Prognosis Case report

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Iron oxide/CNT-based artificial nacre for electromagnetic interference shielding

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Nano Research 2024年第7期17卷 6560-6566页

作者： Cheng-Xin yu yu-feng Meng Bo Yang jun Pang Xiang-Sen Meng Zi-Ye Zhao Qing-yue Wang Li-Bo Mao Zhi-Kun Wu Shu-Hong yu Institute of Physical Science and Information Technology Anhui UniversityHefei 230601China Key Laboratory of Materials Physics Anhui Key Laboratory of Nanomaterials and NanotechnologyCAS Center for Excellence in NanoscienceInstitute of Solid State PhysicsHFIPSChinese Academy of SciencesHefei 230031China Department of Chemistry New Cornerstone Science LaboratoryInstitute of Biomimetic Materials&ChemistryAnhui Engineering Laboratory of Biomimetic MaterialsDivision of Nanomaterials&ChemistryHefei National Research Center for Physical Sciences at the MicroscaleUniversity of Science and Technology of ChinaHefei 230026China

Biological structural materials,despite consisting of limited kinds of compounds,display multifunctionalities due to their complex hierarchical *** some biomimetic strategies have been applied in artificial materials to enhance their mechanical stability,the simultaneous optimization of other functions along with the mechanical properties via biomimetic designs has not been thoroughly ***,iron oxide/carbon nanotube(CNT)-based artificial nacre with both improved mechanical and electromagnetic interference(EMI)shielding performance is fabricated via the mineralization of Fe_(3)O_(4)onto a CNTincorporated *** micro-and nano-structures of the artificial nacre are similar to those of natural nacre,which in turn improves its mechanical *** alternating electromagnetic wave-reflective CNT layers and the wave-absorptive iron oxide layers can improve the multiple reflections of the waves on the surfaces of the reflection layers,which then allows sufficient interactions between the waves and the absorption ***,compared with the reflection-dependent EMI-shielding of the non-structured material,the artificial nacre exhibits strong absorption-dependent shielding behavior even with a very low content of wave-absorptive *** to the high mechanical stability,the shielding effectiveness of the artificial nacre that deeply cut by a blade is still maintained at approximately 70%−96%depending on the incident wave *** present work provides a new way for designing structural materials with concurrently enhanced mechanical and functional properties,and a path to combine structural design and intrinsic properties of specific materials via a biomimetic strategy.

关键词： artificial nacre electromagnetic interference shielding biomineralization biomimetic material hierarchical structure

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Immunomodulation of adipose-derived mesenchymal stem cells on peripheral blood mononuclear cells in colorectal cancer patients with COVID-19

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2113-2122页

作者： jun-feng Wang Xiao-Xia Yang Jian Zhang Yan Zheng Fu-Qing Zhang Xiao-feng Shi yu-Liang Wang Department of Colorectal Oncology Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin’s Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjin 300060China Department of Neurology Tianjin First Center HospitalTianjin 300192China Prosthodontics Studio Tianjin Stomatological HospitalTianjin 300041China Department of Clinical Laboratory Medicine Tianjin Institute of UrologyThe Second Hospital of Tianjin Medical UniversityTianjin 300211China Department of Emergency Tianjin First Central HospitalTianjin 300192China

BACKGROUND Accumulating evidence has shown that adipose tissue-derived mesenchymal stem cells(ADSCs)are an effective therapeutic approach for managing coronavirus disease 2019(COVID-19);however,further elucidation is required to determine their underlying immunomodulatory effect on the mRNA expression of T helper cell-related transcription factors(TFs)and cytokine release in peripheral blood mononuclear cells(PBMCs).AIM To investigate the impact of ADSCs on the mRNA expression of TFs and cytokine release in PBMCs from colorectal cancer(CRC)patients with severe COVID-19(CRC^(+)patients).METHODS PBMCs from CRC^(+)patients(PBMCs-C+)and age-matched CRC patients(PBMCs-C)were stimulated and cultured in the presence/absence of *** mRNA levels of T-box TF TBX21(T-bet),GATA binding protein 3(GATA-3),RAR-related orphan receptor C(RORC),and forkhead box P3(FoxP3)in the PBMCs were determined by reverse transcriptase-polymerase chain *** supernatants were evaluated for levels of interferon gamma(IFN-γ),interleukin 4(IL-4),IL-17A,and transforming growth factor beta 1(TGF-β1)using an enzyme-linked immunosorbent *** Compared with PBMCs-C,PBMCs-C+exhibited higher mRNA levels of T-bet and RORC,and increased levels of IFN-γ and ***,a significant decrease in FoxP3 mRNA and TGF-β1,as well as an increase in Tbet/GATA-3,RORC/FoxP3,IFN-γ/IL-4,and IL-17A/TGF-β1 ratios were observed in PBMCs-C+.Furthermore,ADSCs significantly induced a functional regulatory T cell(Treg)subset,as evidenced by an increase in FoxP3 mRNA and TGF-β1 release *** was accompanied by a significant decrease in the mRNA levels of T-bet and RORC,release of IFN-γ and IL-17A,and T-bet/GATA-3,RORC/FoxP3,IFN-γ/IL-4,and IL-17A/TGF-β1 ratios,compared with the PBMCs-C+*** The present in vitro studies showed that ADSCs contributed to the immunosuppressive effects on PBMCs-C+,favoring Treg ***,ADSC-based cell therapy could be a beneficial approach for p

关键词： Colorectal cancer COVID-19 Adipose-derived mesenchymal stem cells T helper cell Immunomodulation

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Acetaminophen overdose-induced acute liver injury can be alleviated by static magnetic field

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Zoological Research 2024年第3期45卷 478-490页

作者： Han-Xiao Chen Xin-yu Wang Biao yu Chuan-Lin feng Guo-feng Cheng Lei Zhang jun-jun Wang Ying Wang Ruo-Wen Guo Xin-Miao Ji Wen-Jing Xie Wei-Li Chen Chao Song Xin Zhang CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology High Magnetic Field LaboratoryHefei Institutes of Physical ScienceChinese Academy of SciencesHefeiAnhui 230031China Science Island Branch of Graduate School University of Science and Technology of ChinaHefeiAnhui 230026China Institutes of Physical Science and Information Technology Anhui UniversityHefeiAnhui 230601China

Acetaminophen(APAP),the most frequently used mild analgesic and antipyretic drug worldwide,is implicated in causing 46%of all acute liver failures in the USA and between 40%and 70%in *** predominant pharmacological intervention approved for mitigating such overdose is the antioxidant N-acetylcysteine(NAC);however,its efficacy is limited in cases of advanced liver injury or when administered at a late *** the current study,we discovered that treatment with a moderate intensity static magnetic field(SMF)notably reduced the mortality rate in mice subjected to high-dose APAP from 40%to 0%,proving effective at both the initial liver injury stage and the subsequent recovery *** the early phase of liver injury,SMF markedly reduced APAPinduced oxidative stress,free radicals,and liver damage,resulting in a reduction in multiple oxidative stress markers and an increase in the antioxidant glutathione(GSH).During the later stage of liver recovery,application of vertically downward SMF increased DNA synthesis and hepatocyte ***,the combination of NAC and SMF significantly mitigated liver damage induced by high-dose APAP and increased liver recovery,even 24 h post overdose,when the effectiveness of NAC alone substantially ***,this study provides a noninvasive non-pharmaceutical tool that offers dual benefits in the injury and repair stages following APAP *** note,this tool can work as an alternative to or in combination with NAC to prevent or minimize liver damage induced by APAP,and potentially other toxic overdoses.

关键词： Acetaminophen Acute liver injury Static magnetic fields Oxidative stress DNA synthesis

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Water modeling on fluid flow and mixing phenomena in a BOF steelmaking converter

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Journal of Iron and Steel Research International 2024年第3期31卷 595-607页

作者： Xin-yu Cai Hao-jian Duan Ding-han Li Anjun Xu Li-feng Zhang School of Metallurgical and Ecological Engineering University of Science and Technology Beijing(USTB)Beijing 100083China School of Mechanical and Materials Engineering North China University of TechnologyBeijing 100144China

A 1∶8 physical water model was constructed to investigate the fluid flow and mixing phenomena in the basic oxygen furnace(BOF)*** particle image velocimetry was employed to measure the velocity distribution of the bath and the high-speed camera was applied to capture the cavity shape in the combined blowing BOF *** mixing time for varied operating conditions was measured by the stimulus-response *** cavity depth increased with the decrease in the lance height and the increase in the top gas flow rate while the bottom blowing gas had little influence on the cavity *** minimum cavity depth was obtained under the condition of a 69.8 m^(3)/h top gas flow rate,a 287.5 mm lance height and a 0.93 m^(3)/h bottom blowing gas flow rate,which was 161.2 *** mixing time decreased as the lance height decreased and the top blowing gas flow rate *** mixing time was first decreased and then increased with the increase in the bottom gas flow *** the condition of 69.8 m^(3)/h gas flow rate of top blowing,the 287.5 mm lance height and the 0.93 m^(3)/h gas flow rate of bottom blowing,the mixing time in the converter was 48.65 *** empirical formula between the stirring power and the mixing time in the converter was calculated.

关键词： Water model Fluid flow Particle image velocimetry Mixing time BOF converter

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Anomalous thermal expansion and enhanced magnetocaloric effect in<001>-textured Mn_(x)Fe_(5-x)Si_(3) alloys

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Rare Metals 2024年第5期43卷 2263-2274页

作者： Yong Gong Xue-Fei Miao Tapas Samanta Chris Taake jun Liu feng-Jiao Qian Yan-Yan Shao yu-Jing Zhang Qing-Yong Ren Luana Caron feng Xu MIIT Key Laboratory of Advanced Metallic and Intermetallic Materials Technology School of Materials Science and EngineeringNanjing University of Science and TechnologyNanjing210094China Department of Physics Bielefeld University33501BielefeldGermany College of Physics Nanjing University of Aeronautics and AstronauticsNanjing210016China Institute of High Energy Physics Chinese Academy of SciencesBeijing100049China Spallation Neutron Source Science Center Dongguan523803China Guangdong-Hong Kong-Macao Joint Laboratory for Neutron Scattering Science and Technology Dongguan523803China Department of Physics Bielefeld University33501BielefeldGermany Helmholtz-Zentrum Berlin für Materialien und Energie12489BerlinGermany

The development of zero and negative therma expansion(i.e.,ZTE and NTE)materials is of crucial importance to the control of undesirable thermal expansion for high-precision *** the present work,ZTE and NTE were obtained in directionally-solidified Mn_(x)Fe_(5-x)Si_(3)alloys with a strongtexture,in striking contrast to positive thermal expansion in their isotropic counterparts Magnetometry and in-situ X-ray diffraction(XRD)measurements were performed to uncover the origin of the anomalous thermal *** measurements indicate a strong easy-plane magnetocrystalline anisotropy in the textured samples,where the magnetic moments are aligned within the ab plane of the hexagonal structure Temperature-dependent XRD on the x=1 sample reveals a ZTE character in the ab plane that is coupled to a ferromagnetic *** a result,the macroscopic ZTE(~0.22×10^(-6)K^(-1))in the x=1 sample can be attributed to the microscopic magneto volume effect within the ab plane,which is realized by the introduction of the-textured ***,the competition between antiferromagnetic and ferromagnetic exchange coupling leads to NTE in textured x=1.5 and 2 ***,textured x=1 sample displays enhanced magnetocaloric properties as compared to the conventional counterparts with randomly-oriented *** this work demonstrates a new strategy toward the exploration of anomalous thermal expansion properties as well as the enhancement of magnetocaloric properties for materials with a strong magnetocrystalline anisotropy.

关键词： MnFeySis Magnetocaloric effect Magnetic phase transition Negative thermal expansion

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Bayesian partial pooling to reduce uncertainty in overcoring rock stress estimation

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第4期16卷 1192-1201页

作者： yu feng Ke Gao Suzanne Lacasse Norwegian Geotechnical Institute OsloNorway Department of Earth and Space Sciences Southern University of Science and TechnologyShenzhenChina

The state of in situ stress is a crucial parameter in subsurface engineering,especially for critical projects like nuclear waste *** one of the two ISRM suggested methods,the overcoring(OC)method is widely used to estimate the full stress tensors in rocks by independent regression analysis of the data from each OC ***,such customary independent analysis of individual OC tests,known as no pooling,is liable to yield unreliable test-specific stress estimates due to various uncertainty sources involved in the OC *** address this problem,a practical and no-cost solution is considered by incorporating into OC data analysis additional information implied within adjacent OC tests,which are usually available in OC measurement ***,this paper presents a Bayesian partial pooling(hierarchical)model for combined analysis of adjacent OC *** performed five case studies using OC test data made at a nuclear waste repository research site of *** results demonstrate that partial pooling of adjacent OC tests indeed allows borrowing of information across adjacent tests,and yields improved stress tensor estimates with reduced uncertainties simultaneously for all individual tests than they are independently analysed as no pooling,particularly for those unreliable no pooling stress estimates.A further model comparison shows that the partial pooling model also gives better predictive performance,and thus confirms that the information borrowed across adjacent OC tests is relevant and effective.

关键词： Overcoring stress measurement Uncertainty reduction Partial pooling Bayesian hierarchical model Nuclear waste repository

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