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Mobile crowd photographing: another way to watch our world

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Science China(Information Sciences) 2016年第8期59卷 250-274页

作者： Huihui CHEN Bin GUO Zhiwen yu Xingshe ZHOU School of Computer Science Northwestern Polytechnical University School of Computer and Information Engineering Luoyang Institute of Science and Technology

People take and share pictures in the mobile network. Through collecting and computing pictures with built-in contexts, Mobile Crowd Photographing(MCP) can give us a new way to see this world. This paper focuses on participatory picture collection, which is one way of MCP. Three characteristic issues of MCP are proposed, and then our recent work to solve these issues will also be demonstrated.

关键词： mobile crowd photographing task-driven data collection task definition task assignment data selection

Nanoparticle targeting cGAS-STING signaling in disease therapy

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Nano Research 2024年第8期17卷 7315-7336页

作者： Lan Zhou yu Huang yuzhang Wu Shupei Tang Frontier Medical Training Brigade Third Military Medical UniversityHutubi 831200China Department of Gastroenterology Xinqiao HospitalThird Military Medical UniversityChongqing 400037China Institute of Immunology Third Military Medical UniversityChongqing 400038China Shigatse Branch Xinqiao HospitalThird Military Medical UniversityShigatse 857000China

The cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon(IFN)genes(cGAS-STING)signaling pathway is crucial for sensing abnormal DNA accumulation in the *** binds to abnormal DNA,cGAS catalyzes the production of second messenger cyclic dinucleotides,followed by the activation of downstream *** activation induces the expression of type I interferon and other inflammatory cytokines,ultimately initiating an immune *** to the involvement of the cGAS-STING pathway in various diseases,including infection,tumor,autoimmune disease and kidney disease,ongoing research is focused on developing drugs and treatment methods to target and regulate this *** the development of nanotechnology,nanomedicines targeting cGAS-STING signaling are of great significance in clinical applications due to their targeted delivery,controlled drug release,improved solubility,multifunctionality,and enhanced *** comprehensive review focuses on the most recent progress of nanoplatforms targeting cGAS-STING in disease therapy,aiming to provide references and guidelines for further design and optimization of nanomedicines.

关键词： nanomedicine cGAS-STING pathway and related disease anti-tumor nanotherapy anti-viral nanotherapy

Fabrication of form stable NaCl-Al2O3 composite for thermal energy storage by cold sintering process

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Frontiers of Chemical Science and Engineering 2019年第4期13卷 727-735页

作者： Rilvaminu Suleiman Qinghua yu yulong Ding Yongliang Li Birmingham Centre for Energy Storage School of Chemical EngineeringUniversity of BirminghamBirminghamB152TTUK

A form stable NaCl-Al2O3(50-50 wt-%)composite material for high temperature thermal energy storage was fabricated by cold sintering process,a process recently applied to the densification of ceramics at low temperature 300℃ under uniaxial pressure in the presence of small amount o f transient *** fabricated composite achieved as high as 98.65% of the theoretical *** NaCl-Al2O3 composite also retained the chloride salt without leakage after 30 heating-cooling cycles between 750℃-850℃ together with a holding period o f 24h at 850℃.X-ray diffraction measurements indicated congruent solubility o f the alumina in chloride salt,excellent compatibility o f NaCl with Al2O3,and chemical stability at high *** analysis by scanning electron microscope also showed limited grain growth,high density,uniform NaCl distribution and clear faceted composite structure without *** latent heat storage density o f 252.5J/g was obtained from simultaneous thermal *** strength test showed high sintered strength around 5 GPa after 50 *** composite was found to have fair mass losses due to ***,cold sintering process has the potential to be an efficient,safe and cost-effective strategy for the fabrication of high temperature thermal energy storage materials.

关键词： cold sintering process composite fabrication thermal energy storage phase change materials

Mechanical and Frictional Properties of the Elytra of Five Species of Beetles

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Journal of Bionic Engineering 2013年第1期10卷 77-83页

作者： Min yu Ilja Hermann Zhendong Dai Norm Gitis Institute of Bio-inspired Structure and Surface Engineering Nanjing University of Aeronauties and Astronautics Nanjing 210016 P. R. China Bruker Nano Inc. 1717 Dell Ave. Campbell CA 95008 USA

The mechanical and frictional properties of different parts of the elytra of five species of beetle were measured using a nano-indenter and a micro-tribometer. The surface microstructures of the elytra were observed by optical microscopy and scanning white light interferometry. The surface microstructures of the elytra of all five species are characterized as non-smooth concavo-convex although specific morphological differences demonstrate the diversity of beetle elytra. Young＇s modulus and the hardness of the elytral materials vary with the species of beetle and the sampling locations, ranging from 1.80 GPa to 12.44 GPa, and from 0.24 GPa to 0.75 GPa, respectively. In general, both the Young＇s modulus and the hardness are lower in samples taken from the center of the elytra than those taken from other regions, which reflects the functional heterogeneity of biological material in the process of biological evolution. The elytra have very low friction coefficient, ranging from 0.037 to 0.079, which is related to their composition and morphology. Our measurements indicate that the surface texture and its mi- crostructural size of beetle elytra contribute to anti-friction effects.

关键词： beetle elytra bio-tribology surface morphology mechanical properties

Determination of delay time in individual transfer function for central aortic pressure reconstruction

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Science China(Life Sciences) 2014年第10期57卷 1034-1038页

作者： yu DanYang XIANG HaiYan LI Deyu WANG yuQi yu MengSun School of Biological Science and Medical Engineering Beihang University Department of Medical Engineering the 201st Hospital of the Chinese Peoples' s Liberation Army Department of Aviation Medical Engineering Institute of Aviation Medicine

In previous research, time-delay （△t） was a more important parameter than the reflection coefficient in the individual transfer function of central aortic pressure reconstruction. The At can be obtained by electrocardiography （ECG） or phonocardiography （PCG）. Because the pre-ejection period remains an uncertain factor, the present study used ECG and PCG to define the delay time and analyzed the accuracy of the reconstruction results. The △tpre is the actual delay time derived from the aorta to the carotid pressure wave, △tpco is the time delay between the aortic valve component of the second heart sound and the dicrotic incisura of the carotid pressure wave, and AtEcc represents the delay from the interval of the ECG R-peak to the foot of the carotid pressure wave. Compared with the measured aortic pressure, the reconstruction result obtained by △t=△tpcslightly differed from the best result estimated by △t=△tpre. However, the differences between the result obtained by △t=△tEco and the best result were significant in terms of the diastolic blood pressure, and pulse pressure, and especially in terms of the augmentation index and root-mean-square-error. Thus, the At should be determined by PCG for central aortic pressure reconstruction in practice.

关键词： central aortic pressure delay time PCG ECG

Operation and Force Analysis of the Guide Wire in a Minimally Invasive Vascular Interventional Surgery Robot System

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Chinese Journal of Mechanical Engineering 2015年第2期28卷 249-257页

作者： YANG Xue WANG Hongbo SUN Li yu Hongnian Parallel Robot and Mechatronic System Laboratory of Hebei Province Yanshan University School of Mechanical Engineering University of Jinan Key Laboratory of Advanced Forging & Stamping Technology and Science of Ministry of Education Yanshan University Faculty of Science and Technology Bournemouth University

To develop a robot system for minimally invasive surgery is significant,however the existing minimally invasive surgery robots are not applicable in practical operations,due to their limited functioning and weaker perception.A novel wire feeder is proposed for minimally invasive vascular interventional *** is used for assisting surgeons in delivering a guide wire,balloon and stenting into a specific lesion *** contrasting those existing wire feeders,the motion methods for delivering and rotating the guide wire in blood vessel are described,and their mechanical realization is presented.A new resistant force detecting method is given in *** change of the resistance force can help the operator feel the block or embolism existing in front of the guide *** driving torque for rotating the guide wire is developed at different *** the CT reconstruction image and extracted vessel paths,the path equation of the blood vessel is *** the shapes of the guide wire outside the blood vessel,the whole bending equation of the guide wire is *** is a risk criterion in the delivering *** process can make operations safer and man-machine interaction more reliable.A novel surgery robot for feeding guide wire is designed,and a risk criterion for the system is given.

关键词： minimally invasive wire feeder force analysis moment of inertia risk criterion

Removal of 2-ClBP from soil–water system using activated carbon supported nanoscale zerovalent iron

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Journal of Environmental Sciences 2016年第9期28卷 143-152页

作者： Wei Zhang Tian yu Xiaolin Han Weichi Ying State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process School of Resources and Environmental EngineeringEast China University of Science and Technology

We explored the feasibility and removal mechanism of removing 2-chlorobiphenyl（2-Cl BP）from soil–water system using granular activated carbon（GAC） impregnated with nanoscale zerovalent iron（reactive activated carbon or RAC）.The RAC samples were successfully synthesized by the liquid precipitation *** mesoporous GAC based RAC with low iron content（1.32%） exhibited higher 2-Cl BP removal efficiency（54.6%） in the water *** result of Langmuir–Hinshelwood kinetic model implied that the different molecular structures between 2-Cl BP and trichloroethylene（TCE） resulted in more difference in dechlorination reaction rates on RAC than adsorption *** to removing2-Cl BP in the water phase,RAC removed the 2-Cl BP more slowly in the soil phase due to the significant external mass transfer ***,in the soil phase,a better removal capacity of RAC was observed than its base GAC because the chemical dechlorination played a more important role in total removal process for 2-Cl *** important result verified the effectiveness of RAC for removing 2-Cl BP in the soil *** reducing the total RAC removal rate of 2-Cl BP,soil organic matter（SOM）,especially the soft carbon,also served as an electron transfer medium to promote the dechlorination of 2-Cl BP in the long term.

关键词： Reactive activated carbon nZVI 2-ClBP Dechlorination Soil Soil organic matter

New Fabrication and Mechanical Properties of Styrene-Butadiene Rubber/Carbon Nanotubes Nanocomposite

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Journal of Materials Science & Technology 2010年第12期26卷 1127-1132页

作者： Xiangwen Zhou yuefeng Zhu Ji Liang Suyuan yu Key Laboratory for Advanced Materials Processing Technology Ministry of Education Department of Mechanical Engineering Tsinghua University Beijing 100084 China Institute of Nuclear and New Energy Technology Tsinghua University Beijing 100084 China

A novel technology to prepare styrene-butadiene rubber （SBR）/carbon nanotubes （CNTs） composites was developed by combining a spray drying method and a subsequent mechanical mixing process. The cross-linking degrees of the vulcanized composites increased gradually with the additive CNTs contents. By comparing with those of the pure SBR composites, the mechanical properties such as tensile strength, tear strength and hardness of the composites filled with CNTs at certain contents were dramatically improved almost by 600%, 250% and 70%, respectively. The fabrication of the CNTs filled with SBR composites by combination of the spray drying method and subsequent mechanical mixing process was effective for enhancing the reinforcement effects of CNTs in rubbers. The novel technology can also open a new route for the modification and reinforcement on the nanocomposites with large amount of CNTs.

关键词： Carbon nanotubes Styrene-butadiene rubber Spray drying Mechanical mixing Nanocomposite Mechanical property

Systemic modulation of skeletal mineralization by magnesium implant promoting fracture healing: Radiological exploration enhanced with PCA-based machine learning in a rat femoral model

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Journal of Magnesium and Alloys 2024年第3期12卷 1009-1020页

作者： yu Sun Heike Helmholz Regine Willumeit-Römer Institute of Metallic Biomaterials Helmholtz-Zentrum HereonGermany

The clinical application of magnesium(Mg)and its alloys for bone fractures has been well supported by in vitro and in vivo ***,there were studies indicating negative effects of high dose Mg intake and sustained local release of Mg ions on bone metabolism or repair,which should not be ignored when developing Mg-based ***,it remains necessary to assess the biological effects of Mg implants in animal models relevant to clinical treatment *** primary purpose of this study was to validate the beneficial effects of intramedullary Mg implants on the healing outcome of femoral fractures in a modified rat *** addition,the mineralization parameters at multiple anatomical sites were evaluated,to investigate their association with healing outcome and potential clinical *** to the control group without Mg implantation,postoperative imaging at week 12 demonstrated better healing outcomes in the Mg group,with more stable unions in 3D analysis and high-mineralized bridging in 2D *** bone tissue mineral density(TMD)was higher in the Mg group at the non-operated femur and lumbar vertebra,while no differences between groups were identified regarding the bone tissue volume(TV),TMD and bone mineral content(BMC)in *** the surgical femur,the Mg group presented higher TMD,but lower TV and BMC in the distal metaphyseal region,as well as reduced BMC at the osteotomy *** component analysis(PCA)-based machine learning revealed that by selecting clinically relevant parameters,radiological markers could be constructed for differentiation of healing outcomes,with better performance than 2D *** study provides insights and preclinical evidence for the rational investigation of bioactive materials,the identification of potential adverse effects,and the promotion of diagnostic capabilities for fracture healing.

关键词： Magnesium Implants Bone fracture Mineralization Systemic modulation Principal component analysis.