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A blockchain-based transaction system for private data sharing and trading

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Control Theory and Technology 2022年第3期20卷 291-302页

作者： Wei Cui yu Pan Zhendong ai School of Automation Science and Engineering South China University of TechnologyGuangzhou510640GuangdongChina College of Control Science and Engineering Zhejiang UniversityHangzhou310058ZhejiangChina

To address the private data management problems and realize privacy-preserving data sharing,a blockchain-based transaction system named Ecare featuring information transparency,fairness and scalability is *** proposed system formulates multiple private data access control strategies,and realizes data trading and sharing through on-chain transactions,which makes transaction records transparent and *** our system,the private data are encrypted,and the role-based account model ensures that access to the data requires owner’s ***,a new consensus protocol named Proof of Transactions(PoT)proposed by ourselves has been used to improve consensus *** value of Ecare is not only that it aggregates telemedicine,data transactions,and other features,but also that it translates these actions into transaction events stored in the blockchain,making them transparent and immutable to all *** proposed system can be extended to more general big data privacy protection and data transaction scenarios.

关键词： Private data sharing Blockchain Data access control Proof of Transactions

OsTHA8 encodes a pentatricopeptide repeat protein required for RNA editing and splicing during rice chloroplast development

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The Crop Journal 2023年第5期11卷 1353-1367页

作者： Yanwei Wang yu Duan Pengfei ai College of Food and Biology Hebei University of Science and TechnologyShijiazhuang 050018HebeiChina

In higher plants, the chloroplast is the most important organelle for photosynthesis and for numerous essential metabolic processes in the cell. Although many genes involved in chloroplast development have been identified, the mechanisms underlying such development are not fully understood. In this study, a rice(Oryza sativa) mutant exhibiting pale green color and seedling lethality was isolated from a mutant library. The mutated gene was identified as an ortholog of THA8(thylakoid assembly 8) in Arabidopsis and maize. This gene is designated as OsTHA8 hereafter. OsTHA8 showed a typical pentatricopeptide repeat(PPR) characteristic of only four PPR motifs. Inactivation of OsTHA8 led to a deficiency in chloroplast development in the rice seedling stage. OsTHA8 was expressed mainly in young leaves and leaf *** OsTHA8 protein was localized to the chloroplast. Loss of function of OsTHA8 weakened the editing efficiency of ndhB-611/737 and rps8-182 transcripts under normal conditions. Y2H and BiFC indicated that OsTHA8 facilitates RNA editing by forming an editosome with multiple organellar RNA editing factor(OsMORF8) and thioredoxin z(OsTRXz), which function in RNA editing in rice chloroplasts. Defective OsTHA8 impaired chloroplast ribosome assembly and resulted in reduced expression of PEP-dependent genes and photosynthesis-related genes. Abnormal splicing of the chloroplast gene ycf3 was detected in ostha8. These findings reveal a synergistic regulatory mechanism of chloroplast biogenesis mediated by RNA, broaden the function of the PPR family, and shed light on the RNA editing complex in rice.

关键词： Oryza sativa L. Chloroplast biogenesis Pentatricopeptide repeat protein RNA editing RNA splicing

Bioinspired Ultrasensitive Flexible Strain Sensors for Real‑Time Wireless Detection of Liquid Leakage

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nano-Micro Letters 2025年第3期17卷 310-327页

作者： Weilong Zhou yu Du Yingying Chen Congyuan Zhang Xiaowei Ning Heng Xie Ting Wu Jinlian Hu Jinping Qu Key Laboratory of Material Chemistry for Energy Conversion and Storage Ministry of EducationHubei Key Laboratory of Material Chemistry and Service Failure and Hubei Engineering Research Center for Biomaterials and Medical Protective MaterialsSchool of Chemistry and Chemical EngineeringHuazhong University of Science and TechnologyWuhan 430074People’s Republic of China School of Materials Science and Engineering Wuhan Institute of TechnologyWuhan 430205People’s Republic of China Department of Biomedical Engineering City University of Hong KongHong KongSAR 999077People’s Republic of China

Liquid leakage of pipeline networks not only results in considerableresource wastage but also leads to environmental pollution and ecological *** response to this global issue, a bioinspired superhydrophobic thermoplastic polyurethane/carbon nanotubes/graphene nanosheets flexible strain sensor (TCGS) hasbeen developed using a combination of micro-extrusion compression molding andsurface modification for real-time wireless detection of liquid leakage. The TCGSutilizes the synergistic effects of Archimedean spiral crack arrays and micropores,which are inspired by the remarkable sensory capabilities of scorpions. This designachieves a sensitivity of 218.13 at a strain of 2%, which is an increase of 4300%. Additionally, it demonstrates exceptional durability bywithstanding over 5000 usage cycles. The robust superhydrophobicity of the TCGS significantly enhances sensitivity and stability indetecting small-scale liquid leakage, enabling precise monitoring of liquid leakage across a wide range of sizes, velocities, and compositionswhile issuing prompt alerts. This provides critical early warnings for both industrial pipelines and potential liquid leakage scenariosin everyday life. The development and utilization of bioinspired ultrasensitive flexible strain sensors offer an innovative and effectivesolution for the early wireless detection of liquid leakage.

关键词： Thermoplastic polyurethane Bioinspired Cracks Liquid leakage Flexible strain sensor

Endovascular treatment vs drug therapy alone in patients with mild ischemic stroke and large infarct cores

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World Journal of Clinical Cases 2022年第28期10卷 10077-10084页

作者： Wen-Hui Kou Xiao-Qin Wang Jin-Shui Yang nan Qiao Xiao-Hui Nie ai-Mei yu ai-Xia Song Qian Xue Department of Neurology First Affiliated Hospital of Hebei North UniversityZhangjiakou 075061Hebei ProvinceChina

BACKGROUND Treatment decision making is strictly associated with the outcomes in patients with ischemic stroke who show a large core *** care alone may result in suboptimal treatment efficacy,and endovascular treatment may be accompanied by safety *** endovascular treatment is superior to medical care is not well investigated in the clinical *** To investigate the efficacy of endovascular treatment and drug therapy alone in mild ischemic stroke patients with large infarct *** Fifty patients with mild ischemic stroke and 50 patients with acute ischemic stroke caused by anterior large vessel occlusion were selected at the First Affiliated Hospital of Hebei North University between January 2021 and December *** were divided into an endovascular therapy group and a drug therapy group according to different treatment *** the endovascular therapy group,there were 28 patients with minor stroke and 22 patients with large infarct *** drug therapy group had 22 patients with minor stroke and 28 patients with large infarct *** National Institutes of Health Stroke Scale(NIHSS) scores were collected and compared between the two groups immediately after the operation and 24 h and 7 d after the *** modified Rankin scale(m RS) and/or activity of daily living were assessed at hospital *** There was no significant difference in NIHSS scores between the two groups before the operation(P > 0.05).NIHSS scores were lower in the endovascular therapy group than in the drug therapy group at 24 h and 7 d after the operation and at hospital discharge(all P aily living score was better in the endovascular treatment gr

关键词： Ischemic stroke Large infarct cores Endovascular therapy Drug therapy Efficacy

Stability and Stabilization of Sampled-Data Based LFC for Power Systems:A Data-Driven Method

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IEEE/CAA Journal of Automatica Sinica 2025年第1期 291-293页

作者： yu-Long Fan Chuan-Ke Zhang Yong He the School of Automation China University of Geosciences the Hubei Key Laboratory of Advanced Control and Intelligent Automation for Complex Systems the Engineering Research Center of Intelligent Technology for Geo-Exploration Ministry of Education IEEE

Dear Editor,This letter is concerned with stability analysis and stabilization design for sampled-data based load frequency control(LFC) systems via a data-driven method. By describing the dynamic behavior of LFC systems based on a data-based representation, a stability criterion is derived to obtain the admissible maximum sampling interval(MSI) for a given controller and a design condition of the PI-type controller is further developed to meet the required MSI. Finally, the effectiveness of the proposed methods is verified by a case study.

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VF^- and VK^＋ Aggregate Colour Centres： Origin of the Room-Temperature 350 nm Absorption Band in PbWO4

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Chinese Physics Letters 2004年第6期21卷 1131-1134页

作者： ZHANGQi-Ren LIUTing-yu YANFei-nan CollegeofScience UniversityofShanghaiforScienceandTechnologyShanghai200093

A PbWO4 (PWO) single crystal has been grown by the advanced Bridgman method. The as-grown PWO crystal exhibits a weak band at 350nm. This band was fitted into two overlapping bands peaking at 330nm and 360nm respectively. The absorption spectra of the as-grown crystal sample on un-polarized light and polarized light are measured respectively. The formation mechanism of colour centres in the as-grown PWO crystal is discussed and the 330nm and 360nm bands are ascribed to VF− and VK+ centres respectively. The structure models of VF− and VK+ centres are illustrated. The configuration terms, absorption transitions between the energy terms, the absorption spectral features on polarized light and the distributions of VF− and VK+ centres in PWO are systematically studied.

关键词： Light polarization

Microfluidic production of liposomes through liquid-liquid phase separation in ternary droplets

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Frontiers of Chemical Science and Engineering 2022年第6期16卷 1017-1022页

作者： Xu-Chun Song Zi-Han Zhou Ya-Lan yu nan-nan Deng College of Chemistry and Chemical Engineering Southwest Petroleum UniversityChengdu 610500China School of Chemistry and Chemical Engineering Shanghai Jiao Tong UniversityShanghai 200240China

Liposomes,the self-assembled phospholipid vesicles,have been extensively used in various fields such as artificial cells,drug delivery systems,biosensors and ***,current microfluidic routes to liposomes mostly rely on water-in-oil-in-water double emulsion droplets as templates,and require complex fabrication of microfluidic devices,and tedious manipulation of multiphase *** we present a simple microfluidic approach to preparing monodisperse liposomes from oil-in-water *** demonstration,we used butyl acetate-water-ethanol ternary mixtures as inner phase and an aqueous solution of surfactants as outer phase to make oil-in-water droplets,which can evolve into water-in-oil-in-water double emulsion droplets by liquid-liquid phase separation of ternary ***,the resultant water-in-oil-in-water droplets underwent a dewetting transition to form separated monodisperse liposomes and residual oil droplets,with the assistance of *** method is simple,does not require complex microfluidic devices and tedious manipulation,and provides a new platform for controllable preparation of liposomes.

关键词： microfluidics liposomes ternary droplets phase separation

Chemical inequivalence behavior of the protons attached to the same carbon in ethylene-propylene copolymer(EPC)

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Chinese Chemical Letters 2008年第4期19卷 469-474页

作者： Peng yu Bi Hui Ru Dong nan nan Wang College of Science Beijing University of Chemical TechnologyBeijing 100029PR China

Six ethylene-propylene copolymer samples with different structural parameters were analyzed by ^1H NMR,^13C NMR and ^1H-^13C COSY in this *** the aid of the ^1H-^13C COSY spectra of ethylene-propylene copolymer,the chemical inequivalence behavior of the protons attached to the same carbon in the ethylene-propylene copolymer could be observed. Four basic types of chemical bonds were divided,and two kinds of main conformations were proposed to explain this phenomenon. Based on the calculation of conformation distribution,it can be proved that the explanation of this phenomenon was reasonable.

关键词： Chemical inequivalence Ethylene-propylcne copolymer NMR

Targeting epigenetic regulators to overcome drug resistance in cancers

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Signal Transduction and Targeted Therapy 2023年第3期8卷 1070-1093页

作者： nan Wang Ting Ma Bin yu Institute of Drug Discovery&Development School of Pharmaceutical SciencesZhengzhou UniversityZhengzhou 450001China

Drug resistance is mainly responsible for cancer recurrence and poor *** regulation is a heritable change in gene expressions independent of nucleotide sequence *** the common epigenetic regulation mechanisms,DNA methylation,histone modification,and non-coding RNA regulation have been well *** evidence has shown that aberrant epigenetic regulations contribute to tumor ***,targeting epigenetic regulators represents an effective strategy to reverse drug *** this review,we mainly summarize the roles of epigenetic regulation in tumor *** addition,as the essential factors for epigenetic modifications,histone demethylases mediate the histone or genomic DNA ***,we comprehensively describe the functions of the histone demethylase family including the lysine-specific demethylase family,the Jumonji C-domain-containing demethylase family,and the histone arginine demethylase family,and fully discuss their regulatory mechanisms related to cancer drug *** addition,therapeutic strategies,including small-molecule inhibitors and small interfering RNA targeting histone demethylases to overcome drug resistance,are also described.

关键词： epigenetic drug overcome