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The 96-week clinical outcomes after cessation of nucleos(t)ide analog treatment in chronic hepatitis B patients

Gastroenterology Report 2021年第4期9卷 313-322,I0002页

作者： Wen-Xiong Xu Yang-mei Li Jian-Guo Li yong-yu mei You-Ming Chen Xue-Jun Li Chao-Shuang Lin Hong Deng Zhi-Xin Zhao Dong-Ying Xie Zhi-Liang Gao Liang Peng Department of Infectious Diseases The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdongP.R.China Guangdong Key Laboratory of Liver Disease Research The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdongP.R.China Department of Prevention and Health Care The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdongP.R.China

Background:Chronic hepatitis B(CHB)patients have a high virological relapse rate after cessation of nucleos(t)ide analog(NA)treatment,but the clinical outcome remains *** study aimed to investigate the 96-week clinical outcomes and the risk factors for relapse in CHB after cessation of ***:This study was a prospective trial;74 eligible patients were *** patients underwent NA cessation and follow-up according to the 2012 Asian Pacific Association for the Study of the Liver ***,biochemical(aspartate aminotransferase[AST],alanine aminotransferase[ALT],total bilirubin,urea nitrogen,creatinine),virological data(hepatitis B surface antigen[HBsAg],hepatitis B e antigen[HBeAg],hepatitis B e antibody[HBeAb],hepatitis B virus[HBV]DNA levels),and color Doppler ultrasound examination results were recorded and ***:After NA cessation,19 cases were HBsAg-negative without relapse during the 96-week *** the 55 cases of HBsAg-positive after cessation,four types of clinical outcomes were *** patients had no relapse during the 96-week follow-up(type A,21.8%),7 patients underwent virological relapses but spontaneously had a non-virological relapse(type B,12.7%),10 patients maintained virological relapse(type C,18.2%),and 26 patients turned to clinical relapse,received NA retreatment,and achieved ALT normalization and negative conversion of HBV DNA within 12 months(type D,47.3%).The 2-year overall cumulative rates of virological and clinical relapses were 58.1%and 24.3%,*** factors associated with virological relapse were duration of negative HBV DNA,EOT(end of treatment)HBsAg,and original status of *** EOT HBsAg was also an independent factor for clinical ***:There are four types of clinical outcomes in patients with CHB after cessation of NA *** research is needed to explore the mechanism of different clinical *** EOT HBsAg level is an independent

关键词： chronic hepatitis B nucleos(t)ide analogs cessation relapse hepatitis B virus

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Spatial-and spin-resolution ARPES and magnetism beamline at SSRF

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Nuclear Science and Techniques 2024年第8期35卷 23-37页

作者： Fang‑yuan Zhu Jie‑Feng Cao Xiang‑yu Meng Jun‑Qin Li Rui yu Ya‑mei Wang Shan Qiao Bo Zhao Ming‑Zhu Zhang Zhong‑Kai Liu mei‑Xiao Wang yong Wang Ren‑Zhong Tai Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China ShanghaiTech Laboratory for Topological Physics School of Physical Science and TechnologyShanghai Tech UniversityShanghai 201210China University of Chinese Academy of Sciences Beijing 100049China

The BL07U beamline is a new extreme ultraviolet and soft X-ray beamline housed in the Shanghai Synchrotron Radiation Facility. Beamlines are used in nano-resolved angle-resolved photoemission spectroscopy(nano-ARPES), spin-resolved angle-resolved photoemission spectroscopy(spin-ARPES), X-ray magnetic circular dichroism spectroscopy, and X-ray magnetic linear dichroism spectroscopy for certain scientific research. The BL07U beamline, which is based on a pair of elliptical polarized undulators and a variable-included-angle plane-grating monochromator, delivers circularly or linear polarized X-rays within the energy range of 50–2000 eV. The beamline features two branches: One dedicated to nano-ARPES,which has a minimum spot size of only ~ 200 nm, and another branch comprising spin-ARPES, a vector magnetic field, and superconductive magnetic end-station.

关键词： Soft X-ray beamline Nano-ARPES Spin-ARPES XMCD/XMLD

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Relation Between the Eventual Continuity and the E-property for Markov-Feller Semigroups

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Acta Mathematicae Applicatae Sinica 2024年第1期40卷 1-16页

作者： yong Liu Zi-yu Liu LMAM School of Mathematical SciencePeking UniversityBeijing100871China

We investigate some relations between two kinds of semigroup regularities, namely the e-property and the eventual continuity, both of which contribute to the ergodicity for Markov processes on Polish *** precisely, we prove that for Markov-Feller semigroup in discrete time and stochastically continuous MarkovFeller semigroup in continuous time, if there exists an ergodic measure whose support has a nonempty interior,then the e-property is satisfied on the interior of the support. In particular, it implies that, restricted on the support of each ergodic measure, the e-property and the eventual continuity are equivalent for the discrete-time and the stochastically continuous continuous-time Markov-Feller semigroups.

关键词： Markov-Feller semigroup ergodicity e-property eventual continuity

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ASP-Based Programs of Best Linear Unbiased Prediction-Estimated Breeding Values in Breeding Stock

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Animal Husbandry and Feed Science 2010年第10期2卷 4-6,16页

作者： FAN Qiang TIAN Chang-yong yu mei-zi Liaoning Agricultural College Yingkou 115009 China

In order to improve the breeding effect of livestock, the data were read from an Excel file with Active Server Page （ASP） programs, and the breeding values of breeding stock were calculated by best linear unbiased p... 详细信息

关键词： Best linear unbiased prediction Active Server Paget Excel Breeding stock Breeding value

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XOR spin logic operated by unipolar current based on field-free spin-orbit torque switching induced by a lateral interface

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Rare Metals 2024年第8期43卷 3868-3875页

作者： Yan-Ru Li mei-Yin Yang Guo-Qiang yu Bao-Shan Cui Jin-Biao Liu yong-Liang Li Qi-Ming Shao Jun Luo Key Laboratory of Microelectronic Devices and Integrated Technology Institute of MicroelectronicsChinese Academy of Sciences(IMECAS)Beijing 100029China University of Chinese Academy of Sciences(UCAS) Beijing 100049China Songshan Lake Materials Laboratory Dongguan 523808China Institute of Physics Chinese Academy of SciencesBeijing 100190China Key Laboratory for Magnetism and Magnetic Materials of Ministry of Education Lanzhou UniversityLanzhou 730000China Department of Electronic and Computer Engineering The Hong Kong University of Science and TechnologyHong Kong 999077China

Spin logics have emerged as a promising avenue for the development of logic-in-memory *** particular,the realization of XOR spin logic gates using a single spin-orbit torque device shows great potential for low-power stateful logic circuits in the next *** this study,we successfully obtained the XOR logic gate by utilizing a spin-orbit torque device with a lateral interface,which was created by local ion implantation in the Ta/Pt/Co/Ta Hall device exhibiting perpendicular magnetic *** angle of the lateral interface is set at 45°relative to the current direction,leading to the competition between symmetry breaking and current-driven Néel-type domain wall ***,the field-free magnetic switching reversed is realized by the same sign of current amplitude at this *** on this field-free magnetic switching behavior,we successfully proposed an XOR logic gate that could be implemented using only a single spin-orbit torque Hall *** study provides a potentially viable approach toward efficient spin logics and in-memory computing architectures.

关键词： Filed-free magnetic switching Spin-orbit torque XOR logic gate Lateral interface

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汉语学现代转型的前提批判

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东北师大学报（哲学社会科学版） 2006年第1期 103-113页

作者：俞咏梅东北师范大学文学院吉林长春130024

在漫长的历史发展过程中,西方语言文字(印欧语)是沿着音声中心/文字弱化的路径演变的,音义二极性是西方语言学的大前提。而汉语言文字自秦汉以来发生的形态类型简化和汉字形声化的整体演变趋势,则是音声弱化/文字中心的演变路径,形音义... 详细信息

在漫长的历史发展过程中,西方语言文字(印欧语)是沿着音声中心/文字弱化的路径演变的,音义二极性是西方语言学的大前提。而汉语言文字自秦汉以来发生的形态类型简化和汉字形声化的整体演变趋势,则是音声弱化/文字中心的演变路径,形音义三极性是汉语学的大前提。由于中西语言文字类型的体制性差异,汉语学理应把现代转型理解成一个包含三重辩证对立同一关系的概念体系:对立于传统,即现代与前现代应在本体论上实现辩证同一;对立于自身,即元语言与对象语言、主观语法与客观语法应在认识论上实现辩证同一;对立于西方,即个性与共性、民族性与现代性应在方法论上实现辩证同一。

关键词：语言二极结构模式汉语学本体论形声结构模式汉语学认识论汉语学方法论

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Limit Theorems for Critical Galton-Watson Processes with Immigration Stopped at Zero

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Acta Mathematica Sinica,English Series 2024年第2期40卷 435-450页

作者： Dou Dou LI mei ZHANG Xian yu ZHANG College of Statistics and Data Science Faculty of ScienceBeijing University of TechnologyBeijing 100124P.R.China Laboratory of Mathematics and Complex Systems(Ministry of Education) School of Mathematical SciencesBeijing Normal UniversityBeijing 100875P.R.China

In this paper,we consider a critical Galton-Watson branching process with immigration stopped at zero *** precise estimation on the probability generating function of the n-th population are obtained,and the tail prob... 详细信息

关键词： Branching immigration critical life period limit theorems

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Weak Merging Scenario of CLASH Cluster A209

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Research in Astronomy and Astrophysics 2024年第4期24卷 174-182页

作者： Wen-Cheng Feng Heng yu Hai-Hui Zhao Xiao-Lan Hou Shu-mei Jia Cheng-Kui Li yu-Lin Cheng Paolo Tozzi Ming Sun yong Chen Department of Physics and Institute of Theoretical Physics Nanjing Normal UniversityNanjing 210023China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Department of Astronomy Beijing Normal UniversityBeijing 100875China Department of Astronomy Yunnan UniversityKunming 650091China INAF—Osservatorio Astrofisico di Arcetri Largo E.Fermi50122 FirenzeItaly Department of Astronomy University of VirginiaP.O.Box 400325CharlottesvilleVA 22904-4325USA

We study the structural and dynamical properties of A209 based on Chandra and XMM-Newton *** obtain detailed temperature,pressure,and entropy maps with the contour binning method,and find a hot region in the NW *** X-ray brightness residual map and corresponding temperature profiles reveal a possible shock front in the NW direction and a cold front feature in the SE *** with the galaxy luminosity density map we propose a weak merger scenario.A young sub-cluster passing from the SE to NW direction could explain the optical subpeak,the intracluster medium temperature map,the X-ray surface brightness excess,and the X-ray peak offset together.

关键词： X rays:galaxies:clusters galaxies:clusters:intracluster medium galaxies:clusters:Abell 209

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Cosmological interpretation for the stochastic signal in pulsar timing arrays

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Science China(Physics,Mechanics & Astronomy) 2024年第4期67卷 43-50页

作者： yu-mei Wu Zu-Cheng Chen Qing-Guo Huang School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China Department of Astronomy Beijing Normal UniversityBeijing 100875China Advanced Institute of Natural Sciences Beijing Normal UniversityZhuhai 519087China Department of Physics and Synergistic Innovation Center for Quantum Effects and Applications Hunan Normal UniversityChangsha 410081China CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China

The pulsar timing array(PTA)collaborations have recently reported compelling evidence for a stochastic signal consistent with a gravitational-wave *** this paper,we combine the latest data sets from NANOGrav,PPTA,and EPTA to explore cosmological interpretations for the PTA signal from first-order phase transitions,domain walls,and cosmic strings,*** find that the domain wall model is strongly disfavored with the Bayes factors compared with the first-order phase transitions and cosmic strings being 1/90 and 1/189,respectively,breaking the degeneracy among these models in individual data *** also find that:(1)a strong phase transition at temperatures below the electroweak scale is favored,and the bubble collisions make the dominant contribution to the energy density spectrum;(2)a small reconnection probability p<1.55×10^(-1)allowed by strings in(super)string theory is favored at the 95%confidence level,and ground-based detectors can further constrain the parameter space.

关键词： puslar timing arrays gravitational-wave background first-order phase transitions domain walls cosmic strings

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Efficient Monolithic Perovskite/Silicon Tandem Photovoltaics

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Energy & Environmental Materials 2024年第3期7卷 268-281页

作者： yong Wang yu Wang Feng Gao Deren Yang State Key Laboratory of Silicon Materials and School of Materials Science and Engineering Zhejiang UniversityHangzhou 310027China ZJU-Hangzhou Global Scientific and Technological Innovation Center Zhejiang UniversityHangzhou 310014China Department of Physics Chemistry and Biology(IFM)Linköping UniversityLinköping 58183Sweden

Tunable bandgaps make halide perovskites promising candidates for developing tandem solar cells(TSCs),a strategy to break the radiative limit of 33.7%for single-junction solar *** perovskites with market-dominant crystalline silicon(c-Si)is particularly attractive;simple estimates based on the bandgap matching indicate that the efficiency limit in such tandem device is as high as 46%.However,state-of-the-art perovskite/c-Si TSCs only achieve an efficiency of~32.5%,implying significant challenges and also rich *** this review,we start with the operating mechanism and efficiency limit of TSCs,followed by systematical discussions on wide-bandgap perovskite front cells,interface selective contacts,and electrical interconnection layer,as well as photon management for highly efficient perovskite/c-Si *** highlight the challenges in this field and provide our understanding of future research directions toward highly efficient and stable large-scale wide-bandgap perovskite front cells for the commercialization of perovskite/c-Si TSCs.

关键词： 2-terminal electrical interconnection perovskite/silicon tandem photovoltaics photon management wide-bandgap perovskites

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