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高铝TRIP钢连铸过程中保护渣中Al_2O_3含量的变化对渣膜传热的影响

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中国有色金属学报 2011年第4期21卷 913-918页

作者：杨波唐萍文光华于雄重庆大学材料科学与工程学院重庆400044

高Al含量TRIP钢在连铸过程中钢液中的[Al]易与保护渣中的SiO2发生反应,使保护渣中Al2O3含量从3%快速增加至30%左右,导致保护渣的传热性能发生改变,影响连铸坯的质量和连铸工艺操作。利用结晶器保护渣渣膜热流模拟仪研究Al2O3含量对Al-T... 详细信息

高Al含量TRIP钢在连铸过程中钢液中的[Al]易与保护渣中的SiO2发生反应,使保护渣中Al2O3含量从3%快速增加至30%左右,导致保护渣的传热性能发生改变,影响连铸坯的质量和连铸工艺操作。利用结晶器保护渣渣膜热流模拟仪研究Al2O3含量对Al-TRIP钢保护渣传热的影响,并利用扫描电镜、X射线衍射仪分析渣膜的结晶相。结果表明:当Al2O3含量从3%增加到20%时,保护渣的热流密度显著降低;当保护渣的Al2O3含量从20%增加到30%时,保护渣的热流密度先增加后减少;随w(Al2O3)/w(SiO2)比值的增大热流密度逐渐降低,并且在本实验条件下保护渣中会析出CaF2晶体。

关键词： Al-TRIP钢结晶器保护渣 Al2O3 热流密度

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结晶器保护渣渣膜结构的模拟研究

过程工程学报 2011年第2期11卷 349-354页

作者：杨波唐萍文光华朱辛白于雄重庆大学材料科学与工程学院重庆400044

通过获得现场不同位置及由结晶器渣膜热流模拟仪获得不同时刻的渣膜,对比分析了渣膜的厚度、结晶率、晶体的分布、大小、类型.结果表明,结晶器渣膜热流模拟仪铜探头浸入45s时获得的实验室渣膜与现场弯月面附近45s的现场渣膜厚度和结晶... 详细信息

通过获得现场不同位置及由结晶器渣膜热流模拟仪获得不同时刻的渣膜,对比分析了渣膜的厚度、结晶率、晶体的分布、大小、类型.结果表明,结晶器渣膜热流模拟仪铜探头浸入45s时获得的实验室渣膜与现场弯月面附近45s的现场渣膜厚度和结晶率相当;现场渣膜随位置在晶体分布上演变规律与实验室渣膜随时间的演变类似;现场渣膜与实验室渣膜的晶体的类型相同,但是晶体大小还存在差异.因此,可以通过结晶器渣膜热流模拟仪方便、有效的模拟实际结晶器内保护渣渣膜的结晶行为.

关键词：保护渣厚度结晶率渣膜结构渣膜热流模拟仪

Measurement of the ^(232)Th(n,f)cross section in the 1-200 MeV range at the CSNS Back-n

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Nuclear Science and Techniques 2023年第8期34卷 142-153页

作者： Zhi-Zhou Ren Yi-Wei yang Yong-Hao Chen Rong Liu Bang-Jiao Ye Jie wen Hai-Rui Guo Zi-Jie Han Qi-ping Chen Zhong-Wei wen Wei-Li Sun Han Yi Xing-Yan Liu Tao Ye Jiang-bo Bai Qi An Jie Bao yu Bao ping Cao Hao-Lei Chen Zhen Chen Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Ke-Qing Gao Xiao-Long Gao Min-Hao Gu Chang-Cai Han Guo-Zhu He Yong-Cheng He yang Hong Yi-Wei Hu Han-xiong huang Xi-Ru huang Hao-yu Jiang Wei Jiang Zhi-Jie Jiang Han-Tao Jing Ling Kang bo Li Chao Li Jia-wen Li Qiang Li Xiao Li yang Li Jie Liu Shu-Bin Liu Ze Long guang-yuan Luan Chang-Jun Ning Meng-Chen Niu Bin-Bin Qi Jie Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Jia Sun Zhi-Xin Tan Jing-yu tang Xin-Yi tang Bin-Bin Tian Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Xiao-guang Wu Xuan Wu Li-Kun Xie Xiao-yun yang Li yu Tao yu Yong-Ji yu Guo-Hui Zhang Lin-Hao Zhang Qi-Wei Zhang Xian-Peng Zhang yu-Liang Zhang Zhi-Yong Zhang Lu-ping Zhou Zhi-Hao Zhou Ke-Jun Zhu Department of Modern Physics University of Science and Technology of ChinaHefei 230026China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China Institute of Applied Physics and Computational Mathematics Beijing 100088China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230027China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijingChina Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China Department of Engineering and Applied Physics University of Science and Technology of ChinaHefei 230026China

The ^(232)Th(n,f)cross section is very important in basic nuclear physics and applications based on the Th/U fuel *** the time-of-flight method and a multi-cell fast-fission ionization chamber,a novel measurement of the^(232)Th(n,f)cross sec-tion relative to^(235)U in the 1–200 MeV range was performed at the China Spallation Neutron Source Back-n white neutron source(Back-n).The fission event-neutron energy spectra of^(232)Th and^(235)U fission cells were measured in the single-bunch *** 232Th/235U fission cross-sectional ratios were obtained,and the measurement uncertainties were 2.5–3.7%for energies in the 2–20 MeV range and 3.6–6.2%for energies in the 20–200 MeV ***^(232)Th(n,f)cross section was obtained by introducing the standard cross section of^(235)U(n,f).The results were compared with those of previous theoreti-cal calculations,measurements,and *** measured 232Th fission cross section agreed with the main evaluation results in terms of the experimental uncertainty,and 232Th fission resonances were observed in the 1–3 MeV *** present results provide^(232)Th(n,f)cross-sectional data for the evaluation and design of Th/U cycle nuclear systems.

关键词： 232Th(n f)cross section Fast-fission ionization chamber Back-n white neutron source

Study of the response of 10B-doped MCP to wide-energy range neutrons from eV to MeV

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Nuclear Science and Techniques 2024年第8期35卷 132-141页

作者： Qiang Li Li‑Jiao Wang Xiang‑Biao Qiu Jing‑wen Li Wei Xu Tao Li Ze‑Bin Lin Chang‑Jun Ning Yong‑Hao Chen Rui‑Rui Fan Kang Sun Jing‑yu tang Rong Zhang Han‑Tao Jing bo Mei Qi An Hao‑Fan Bai Jiang‑bo Bai Jie Bao ping Cao Qi‑ping Chen Zhen Chen Zeng‑Qi Cui An‑Chuan Fan Chang‑Qing Feng Fan‑Zhen Feng Ke‑Qing Gao Min‑Hao Gu Chang‑Cai Han Zi‑Jie Han Guo‑Zhu He Yong‑Cheng He yang Hong Yi‑Wei Hu Han‑xiong huang Wei‑hua Jia Hao‑yu Jiang Wei Jiang Zhi‑Jie Jiang Zheng‑Yao Jin Ling Kang bo Li Chao Li Gong Li Jia‑wen Li Xiao Li yang Li Jie Liu Rong Liu Shu‑Bin Liu guang‑yuan Luan Bin‑Bin Qi Jie Ren Zhi‑Zhou Ren Xi‑Chao Ruan Zhao‑Hui Song Zhi‑Xin Tan Sheng‑Da tang Peng‑Cheng Wang Zhao‑Hui Wang Zhong‑Wei wen Xiao‑guang Wu Xuan Wu Li‑Kun Xie Yi‑Wei yang Han Yi Yong‑Ji yu Guo‑Hui Zhang Lin‑Hao Zhang Mo‑Han Zhang Qi‑Wei Zhang Xian‑Peng Zhang yu‑Liang Zhang yue Zhang Zhi‑Yong Zhang Mao‑yuan Zhao Lu‑ping Zhou Zhi‑Hao Zhou Ke‑Jun Zhu Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Dongguan Songshan Lake Future School Dongguan 523808China North Night Vision Science&Technology(Nanjing)Research Institute Co.Ltd. Nanjing 211106China Sino‑French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China USTC Archaeometry Lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Neutron-sensitive microchannel plates(nMCPs)have applications in neutron detection,including energy spectrum measurements,neutron-induced cross sections,and neutron imaging.10B-doped MCPs(B-MCPs)have attracted significant attention owing to their potential for exhibiting a high neutron detection efficiency over a large neutron energy *** spatial and temporal resolutions are useful for neutron energy-resolved ***,their practical applications still face many technical *** this study,a B-MCP with 10 mol%10B was tested for its response to wide-energy neutrons from eV to MeV at the Back-n white neutron source at the China Spallation Neutron *** neutron detection efficiency was calibrated at 1 eV,which is approximately 300 times that of an ordinary MCP and indicates the success of 10 B *** factors that caused the reduction in the detection efficiency were simulated and *** neutron energy spectrum obtained using B-MCP was compared with that obtained by other measurement methods,and showed very good consistency for neutron energies below tens of *** response is more complicated at higher neutron energy,at which point the elastic and nonelastic reactions of all nuclides of B-MCP gradually become *** is beneficial for the detection of neutrons,as it compensates for the detection efficiency of B-MCP for high-energy neutrons.

关键词： Neutron radiation image 10B-doped MCP Neutron response Wide-energy range neutrons

Back-n white neutron source at CSNS and its applications

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Nuclear Science and Techniques 2021年第1期32卷 95-104页

作者： Jing-yu tang Qi An Jiang-bo Bai Jie Bao yu Bao ping Cao Hao-Lei Chen Qi-ping Chen Yong-Hao Chen Zhen Chen Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Ke-Qing Gao Xiao-Long Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He yang Hong Yi-Wei Hu Han-xiong huang Xi-Ru huang Hao-yu Jiang Wei Jiang Zhi-Jie Jiang Han-Tao Jing Ling Kang bo Li Chao Li Jia-wen Li Qiang Li Xiao Li yang Li Jie Liu Rong Liu Shu-Bin Liu Xing-Yan Liu Ze Long guang-yuan Luan Chang-Jun Ning Meng-Chen Niu Bin-Bin Qi Jie Ren Zhi-Zhou Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Jia Sun Zhi-Xin Tan Xin-Yi tang Bin-Bin Tian Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei wen Xiao-guang Wu Xuan Wu Li-Kun Xie Xiao-yun yang Yi-Wei yang Han Yi Li yu Tao yu Yong-Ji yu Guo-Hui Zhang Lin-Hao Zhang Qi-Wei Zhang Xian-Peng Zhang yu-Liang Zhang Zhi-Yong Zhang Lu-ping Zhou Zhi-Hao Zhou Ke-Jun Zhu 无 State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China Department of Engineering and Applied Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China The CSNS Back-n Collaboration

Back-streaming neutrons from the spallation target of the China Spallation Neutron Source(CSNS)that emit through the incoming proton channel were exploited to build a white neutron beam facility(the so-called Back-n white neutron source),which was completed in March *** Back-n neutron beam is very intense,at approximately 29107 n/cm2/s at 55 m from the target,and has a nominal proton beam with a power of 100 kW in the CSNS-I phase and a kinetic energy of 1.6 GeV and a thick tungsten target in multiple slices with modest moderation from the cooling water through the *** addition,the excellent energy spectrum spanning from 0.5 eV to 200 MeV,and a good time resolution related tothe time-of-flight measurements make it a typical white neutron source for nuclear data measurements;its overall performance is among that of the best white neutron sources in the *** with advanced spectrometers,detectors,and application utilities,the Back-n facility can serve wide applications,with a focus on neutron-induced cross-sectional *** article presents an overview of the neutron beam characteristics,the experimental setups,and the ongoing applications at Backn.

关键词： White neutron source Nuclear data measurements Experimental setups Neutron applications

Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n

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Nuclear Science and Techniques 2024年第1期35卷 178-187页

作者： Sheng-Da tang Yong-Hao Chen Jing-yu tang Rui-Rui Fan Qiang Li Gong Li Dong Liu Zheng-Yao Jin Xing-Zhu Cui Tian-Xiang Chen Yi-Wei yang Rong Liu Han Yi yang Li Zhen yang Qi An Hao-Fan Bai Jiang-bo Bai Jie Bao ping Cao Qi-ping Chen Zhen Chen Zeng-Qi Cui An-Chuan Fan Chang-Qing Feng Fan-Zhen Feng Ke-Qing Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He yang Hong Yi-Wei Hu Han-xiong huang Wei-hua Jia Hao-yu Jiang Wei Jiang Zhi-jie Jiang Ling Kang bo Li Chao Li Jia-wen Li Xiao Li Jie Liu Shu-Bin Liu guang-yuan Luan Chang-Jun Ning Bin-Bin Qi Jie Ren Zhi-Zhou Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Xin Tan Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei wen Xiao-guang Wu Xuan Wu Li-Kun Xie Yong-Ji yu Guo-Hui Zhang Lin-Hao Zhang Mo-Han Zhang Qi-Wei Zhang Xian-Peng Zhang yu-Liang Zhang yue Zhang Zhi-Yong Zhang Mao-yuan Zhao Lu-ping Zhou Zhi-Hao Zhou Ke-Jun Zhu Sino-French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China Institute of High-Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China USTC Archaeometry Laboratory University of Science and Technology of ChinaHefei 230026China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Nondestructive and noninvasive neutron assays are essential applications of neutron *** resonance transmission analysis(NRTA)is a powerful nondestructive method for investigating the elemental composition of an *** back-streaming neutron line(Back-n)is a newly built time-of-flight facility at the China Spallation Neutron Source(CSNS)that provides neutrons in the eV to 300 MeV range.A feasibility study of the NRTA method for nuclide identification was conducted at the CSNS Back-n via two test *** results demonstrate that it is feasible to identify different elements and isotopes in samples using the NRTA method at *** study reveals its potential future applications.

关键词： CSNS White neutron beam NRTA Nuclide identification Nondestructive method

Advanced Space-based Solar Observatory(ASO-S):an overview

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Research in Astronomy and Astrophysics 2019年第11期19卷 3-10页

作者： Wei-Qun Gan Cheng Zhu yuan-Yong Deng Hui Li yang Su Hai-Ying Zhang bo Chen Zhe Zhang Jian Wu Lei Deng yu huang Jian-Feng yang Ji-Jun Cui Jin Chang Chi Wang Ji Wu Zeng-Shan Yin wen Chen Cheng Fang Yi-hua Yan Jun Lin Wei-Ming xiong Bin Chen Hai-Chao Bao Cai-Xia Cao Yan-ping Bai Tao Wang Bing-Long Chen Xin-yu Li Ye Zhang Li Feng Jiang-Tao Su Ying Li Wei Chen You-ping Li Ying-Na Su Hai-Yan Wu Mei Gu Lei huang Xue-Jun tang Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210034China Innovation Academy for Microsatellites Chinese Academy of SciencesShanghai 201203China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Nanjing Institute of Astronomical Optics&Technology National Astronomical ObservatoriesChinese Academy of SciencesNanjing 210042China Changchun Institute of Optics Fine Mechanics and PhysicsChangchun 130033China Xi’an Institute of Optics and Precision Mechanics Chinese Academy of SciencesXi’an 710119China National Space Science Center Chinese Academy of SciencesBeijing 100190China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China yunnan Observatories Chinese Academy of SciencesKunming 650011China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 101408China Beijing Special Engineering and Design Institute Beijing 100028China Beijing Institute of Tracking and Telecommunications Technology Beijing 100094China Shanghai Academy of Spaceflight Technology Shanghai 201109China

The Advanced Space-based Solar Observatory(ASO-S)is a mission proposed for the 25 th solar maximum by the Chinese solar *** scientific objectives are to study the relationships between the solar magnetic field,solar flares and coronal mass ejections(CMEs).Three payloads are deployed:the Full-disk vector Magneto Graph(FMG),the Lyman-αSolar Telescope(LST)and the Hard X-ray Imager(HXI).ASO-S will perform the first simultaneous observations of the photospheric vector magnetic field,non-thermal imaging of solar flares,and the initiation and early propagation of CMEs on a single ***-S is scheduled to be launched into a 720 km Sun-synchronous orbit in *** paper presents an overview of the mission till the end of Phase-B and the beginning of Phase-C.

关键词： space vehicles instruments-Sun magnetic fields-Sun flares-Sun CMEs-Sun UV radiation-Sun X-ray,gamma-rays

In-beam gamma rays of CSNS Back-n characterized by black resonance filter

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Nuclear Science and Techniques 2024年第10期35卷 149-160页

作者： Jin-Cheng Wang Jie Ren Wei Jiang Xi-Chao Ruan Ying-Yi Liu Hao-Lan yang Kuo-Zhi Xu Xin-Yi Pan Qi Sun Jie Bao Han-xiong huang Hao-Fan Bai Jiang-bo Bai ping Cao Qi-ping Chen Yong-Hao Chen wen-Hao Duan An-Chuan Fan Rui-Rui Fan Chang-Qing Feng Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He yang Hong Yi-Wei Hu Zhi-Jie Jiang Ling Kang Chang-Lin Lan bo Li Feng Li Qiang Li Xiao Li yang Li Jie Liu Rong Liu Shu-Bin Liu Yi-Na Liu guang-yuan Luan Chang-Jun Ning Yi-Jia Qiu wen-Kai Ren Zhi-Zhou Ren Zhao-Hui Song Kang Sun Zhi-Xin Tan Jing-yu tang Sheng-Da tang Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei wen Xiao-guang Wu Xuan Wu Ze-Peng Wu Cong Xia Li-Kun Xie Han Yi Tao yu Yong-Ji yu Guo-Hui Zhang Hang-Chang Zhang Qi-Wei Zhang Xian-Peng Zhang yu-Liang Zhang Zhi-Yong Zhang Mao-yuan Zhao Zhi-Hao Zhou Ke-Jun Zhu Chong Zou Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Modern Physics Fudan UniversityShanghai 200433China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230026China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China USTC Archaeometry Lab University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China Institute of Advanced Technology University of Science and Technology of ChinaHefei 230027China

The back-streaming white-neutron beamline(Back-n)of the China Spallation Neutron Source is an essential neutronresearch platform built for the study of nuclear data,neutron physics,and neutron *** types of cross-sectional neutron-reaction measurements have been performed at Back-n since early *** measurements have shown that a significant number of gamma rays can be transmitted to the experimental stations of Back-n along with the neutron *** gamma rays,commonly referred to as in-beam gamma rays,can induce a non-negligible experimental background in neutron-reaction *** the characteristics of in-beam gamma rays is important for understanding the experimental ***,measuring in-beam gamma rays is challenging because most gamma-ray detectors are sensitive to neutrons;thus,discriminating between neutron-induced signals and those from in-beam gamma rays is *** this study,we propose the use of the black resonance filter method and a CeBr_(3) scintillation detector to measure the characteristics of the in-beam gamma rays of *** types of black resonance filters,^(181)Ta,^(59)Co,^(nat)Ag,and^(nat)Cd,were used in this *** time-of-flight(TOF)technique was used to select the detector signals remaining in the absorption region of the TOF spectra,which were mainly induced by in-beam gamma *** energy distribution and flux of the in-beam gamma rays of Back-n were determined by analyzing the deposited energy spectra of the CeBr_(3) scintillation detector and using Monte Carlo *** on the results of this study,the background contributions from in-beam gamma rays in neutron-reaction measurements at Back-n can be reasonably evaluated,which is beneficial for enhancing both the experimental methodology and data analysis.

关键词： In-beam gamma rays Back-n CeBr_(3)scintillator Black filter resonance technique

Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection:a randomized trial

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Signal Transduction and Targeted Therapy 2021年第10期6卷 3009-3018页

作者： Jun Liu Dan-Dan Li Wei Dong yu-Qi Liu yang Wu Da-Xuan tang Fu-Chun Zhang Meng Qiu Qi hua Jing-yu He Jun Li Bai Du Ting-Hai Du Lin-Lin Niu Xue-Jun Jiang bo Cui Jiang-Bin Chen yang-Gan Wang Hai-Rong Wang Qin yu Jing He Yi-Lin Mao Xiao-Fang Bin yue Deng yu-Dan Tian Qing-hua Han Da-Jin Liu Li-Qin Duan Ming-Jun Zhao Cui-Ying Zhang Hai-Ying Dai Ze-hua Li Ying Xiao You-Zhi Hu Xiao-yu huang Kun Xing Xin Jiang Chao-Feng Liu Jing An Feng-Chun Li Tao Tao Jin-Fa Jiang Ying yang Yao-Rong Dong Lei Zhang guang Fu Ying Li Shu-Wei huang Li-ping Dou Lan-Jun Sun Ying-Qiang Zhao Jie Li yun Xia Jun Liu Fan Liu wen-Jin He Ying Li Jian-Cong Tan yang Lin Ya-Bin Zhou Jian-Fei yang Guo-Qing Ma Hui-Jun Chen He-ping Liu Zong-Wu Liu Jian-xiong Liu Xiao-Jia Luo Xiao-Hong Bin Ya-Nan yu Hai-Xia Dang Bing Li Fei Teng Wang-Min Qiao Xiao-Long Zhu Bing-Wei Chen Qi-guang Chen Chun-Ti Shen Yong-Yan Wang yun-Dai Chen Zhong Wang Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijingChina Department of Cardiology Chinese PLA General HospitalBeijingChina Department of Cardiology Dongfang Hospital Affiliated to Beijing University of Chinese MedicineBeijingChina Department of Geratology Peking University Third HospitalBeijingChina Department of Cardiology Xuan Wu HospitalCapital Medical UniversityBeijingChina Department of Cardiology Guang'anmen HospitalChina Academy of Chinese Medical SciencesBeijingChina Department of Cardiology First Affiliated Hospital of Henan University of Chinese MedicineZhengzhouHenanChina Department of Cardiology Wuhan University Renmin HospitalWuhanHubeiChina Department of Cardiology Wuhan University Zhongnan HospitalWuhanHubeiChina Affiliated Zhongshan Hospital of Dalian University DalianLiaoningChina Department of Cardiology Second Affiliated Hospital to Hunan University of Chinese MedicineChangshaHunanChina Department of Cardiology First Affiliated Hospital to Changchun University of Chinese MedicineChangchunJilinChina Department of Cardiology First Affiliated Hospital to Shanxi Medical UniversityTaiyuanShanxiChina Department of Cardiology Affiliated Hospital of Shanxi University of Chinese MedicineXianyangShanxiChina Department of Cardiology Changsha Central HospitalChangshaHunanChina Department of Cardiology Hubei Provincial Hospital of Traditional Chinese MedicineWuhanHubeiChina Department of Cardiology Shanxi Provincial People's HospitalXi'anShanxiChina Department of Cardiology Shanxi Province Hospital of Traditional Chinese MedicineXi'anShanxiChina Department of Cardiology Xi'an City Hospital of Traditional Chinese MedicineXi'anShanxiChina Department of Cardiology Shanghai Tongji HospitalShanghaiChina Department of Cardiology Shanghai Municipal Hospital of Traditional Chinese MedicineShanghaiChina Department of Cardiology The First Hospital of ChangshaChangshaHunanChina Department of Cardiology Xinhua Hospi

It's a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in thedfferentiated populations with complex diseases,as stable coronary heart ***,in an adaptive,31-center,randomized,double-blind trial invoving 920 patients with moderate symptomatic stable angina treated by 14-day Danhong injection(DHI),a kind of polyphamacological drug with high quality control,or placebo(0.9%saline),with 76-day following-up,we firstly confrmed that DHl couldincrease the proportion of patients with clinically significant changes on angina-frequency assessed by Seattle Angina Questionnaire(ASAQ-AF220)(12.78%at Day 30,95%confidence interval[C]5.86-19.71%,P=0.0003,13.82%at Day 6C0,95%CI 6.82-20.82%,P=0.0001and 8.95%at Day 90,95%CI 2.06-15.85%,P=0.01).We also found that there were no significant differences in new-onset major vascularevents(P=0.8502)and serious adverse events(P=0.9105)between DHl and *** performing the RNA sequencing in 62 selectedpatients,we developed a systemic modular approach tp identfy differentilly expressed modules(DEMs)of DHI with the Z_(summay)valueless than 0 compared with the control group,calculated by weighted gene co-expression network analysis(WGCNA),and sketched out thebasic framework on a modular map with 25 functional modules targeted by ***,the effective therapeutic module(ETM),defined as the highest corelation value with the phenotype alteration(SAQ-AF,the change in SAQ-AF at Day 30 from baseline)calculatedby WGCNA,was identifed in the population with the best effect(ASAQ-AF240),which is related to anticoagulation and regulation ofcholesterol *** assessed the modular flexbility of this ETM using the global topological D value based on Euclidean distance,which is corelated with phenotype alteration(r^(2):0.8204,P=0.019)by linear *** study identified the ant-angina therapeuticmodule in the effective population treated by the multi-target

关键词： angina injection sketch