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Efficacy of active compounds of Chanqin granules on airway neurogenic inflammation induced by PM2.5 in vivo

Journal of Traditional Chinese Medicine 2020年第5期40卷 792-802页

作者： Ju Ya Shen Ruobing yu xiaoping Department of Traditional Chinese Medicine Shuguang HospitalShanghai University of Traditional Chinese MedicineShanghai 200120China

OBJECTIVE:To investigate the efficacy of active compounds of Chanqin(CQ)granules on PM2.5-induced airway neurogenic inflammation in vivo,and to elucidate the underlying mechanisms of ***:The Traditional Chinese Medicine systems pharmacology(TCMSP)database was searched,and the results were combined with oral bioavailability and drug analysis to identify the compounds in CQ *** pharmacophore modeling approach was used to predict the compound targets,and the diseases corresponding to the targets were obtained by searching the therapeutic target database(TTD),pharmacogenomics knowledgebase(Pharm GKB)and Drug Bank *** software was used to construct the network pharmacological charts for Component-Target and Target-Disease interactions of the CQ ***,the mechanisms of action and effectiveness of CQ granules for the treatment of PM2.5-induced airway neurogenic inflammation were ***:A total of 195 compounds and 171 targets were obtained from the analyses.A total of569 corresponding diseases were identified for these ***-target and target-disease networks were *** possible mechanisms and effective components in CQ granules for treating airway neurogenic inflammation were ***,kaempferol and isorhamnetin,beta-sitosterol and sitosterol,which are typically found in the formulation,have extensive pharmacological activities,including anti-inflammatory,antioxidant and antiviral actions and neuroprotective *** these targets,androgen receptor,estrogen receptor,prostaglandin G/H synthase 2,and inducible nitric oxide synthase play important pathological roles,including the induction of neurogenic *** granules may have therapeutic effectiveness for numerous diseases in addition to respiratory diseases,including neoplasms,digestive system diseases,cardiovascular diseases,respiratory tract diseases and nervous system *** vivo,CQ granules are effective in trea

关键词： Neurogenic inflammation Pharmacology Neuropeptides MAP kinase signaling system Ganglia,spinal PM2.5 Chan Qin granules

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A Multi-component Decomposition Method for Polarimetric SAR Data

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Chinese Journal of Electronics 2017年第1期26卷 205-210页

作者： WEI Jujie ZHAO Zheng yu xiaoping LU Lijun Chinese Academy of Surveying and Mapping Institute of Remote Sensing and Digital Earth Chinese Academy of Sciences

There are more unknowns than equations to solve for previous four-component decomposition methods. So they have to determine each scattering power with some assumptions and avoid negative powers in decomposed results with physical power *** paper presents a multi-component decomposition for multi-look Polarimetric SAR(Pol SAR) data by combining the Generalized similarity parameter(GSP) and the eigenvalue decomposition. It extends the existing fourcomponent decomposition by adding the diffuse scattering as the fifth scattering component considering additional cross-polarized power that could represent terrain effects and rough surface scattering. And unlike the previous methods, the new method determines the volume scattering contribution by a modified nonnegative eigenvalue decomposition method and utilizes the GSP to determine the negative powers of the three scattering contributions(i.e., odd-bounce, double-bounce, and diffuse scattering)directly without extra assumptions and constraints. By experiment, the new method is proved to be more straightforward and reasonable.

关键词： Multi-component decomposition Polarimetric SAR(PolSAR) Generalized similarity parameter(GSP)

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Post-fledging dispersal and habitat use of a reintroduced population of the Crested Ibis (Nipponia nippon)

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Chinese Birds 2014年第1期5卷 49-57页

作者： Zhiping Huo Junfeng Guo Xia Li xiaoping yu College of Life Sciences Shaanxi Normal University Reintroduction Center of Crested Ibis of Ningshan

Background: Knowledge of dispersal movement of birds and their habitat preference during the post-fledging period is fundamental to the understanding of their ecological and evolutionary processes. The Crested Ibis is now being reintroduced to protected sites within its historical range, with the goal of establishing a self-sustaining population that may eventually qualify the species for ***: We carried out an ecological study of post-fledging dispersal and habitat use of a reintroduced population of the Crested Ibis(Nipponia nippon) from 2008 to 2012 in Ningshan County, China, by using banding and radio-telemetry ***: In about two weeks(an average of 14.3 days) after fledging, the activities of the fledglings were concentrated in a range of about 100 m around their natal sites, such as the oak-pine forest patches at the edge of open *** this period, fledglings were still partially dependent upon parental care and fed typically on a daily *** increasingly became independent by mid-August and then gradually moved away from their natal sites to post-fledging dispersal locations. During the period of the post-fledging dispersal process, most juveniles moving southwest were concentrated at the mean direction(μ = 254.6°, ? = 70.5°) with a mean dispersal distance of 5.1 *** took an average of 56.4 days to disperse from the natal territory to the first wintering area. Also, forging habitats for juvenile ibis varied with time and local conditions. For example, paddy fields were used most frequently among all habitat types, while shallow rivers just from August to October. Masson pine(Pinus massoniana) was often regarded as the roosting tree species preferred by the Crested Ibis, with the highest utilization rate among all the roosting habitat types. The juveniles of the wild population dispersed four times as far as that of the reintroduced population, but the overall pattern of post-fledging dispersal is similar for the r

关键词： Crested Ibis Ningshan County Post-fledging dispersal Habitat use Reintroduced population

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Metastable Phase Equilibrium in the Reciprocal Quaternary System LiCl＋MgCl2＋Li2SO4＋MgSO4＋H2O at 348.15 K and 0.1 MPa

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Chemical Research in Chinese Universities 2018年第5期34卷 798-802页

作者： yu xiaoping WANG Qin GUO Yafei DENG Tianlong Tianjin Key Laboratory of Marine Resources and Chemistry College of Chemical Engineering and Materials Science Tianjin University of Science and Technology Tianjin 300457 P. R. China College of Chemistry and A laterials Science Northwest University Xi 'an 710127 P. R. China

The metastable solubilities and the physicochemical properties including density and pH of the reciprocal quaternary system（LiCl＋MgCl2＋Li2SO4＋MgSO4＋H2O） at 348.15 K and 0.1 MPa were determined using the isother- mal evaporation method. The dry-salt diagram and water-phase diagram were plotted based on the experimental data. There are five invariant points, eleven tmivariant curves, and seven crystallization zones corresponding to hexahy- drite, tetrahydrite, kieserite, bischofite, lithium sulfate monohydrate, lithium chloride monohydrate and lithium car- nallite. Comparison between the stable and metastable diagrams at 348.15 K indicates that the metastable phenome- non of magnesium sulfate is obvious, and the crystallization regions of hexahydrite and tetrahydrite disappear in the stable phase diagram. A comparison of the metastable dry-salt phase diagrams at 308.15, 323.15 and 348.15 K shows that with the increasing of temperatttre the epsomite crystallization zone disappears from the dry-salt phase diagranl of 303.15 K, and a new kieserite crystallization zone is presented at 348.15 K. The density and pH in the metastable equilibrium solution present regular change with the increasing of Janecke index J（2Li＋）, and the calculated densities using the empirical equation agree well with the experimental values.

关键词： Phase equilibrium Phase diagram Solubility Quaternary system Lithium salt

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Antimony speciation at the sediment-water interface of the Poyang Lake: response to seasonal variation

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Journal of Oceanology and Limnology 2018年第6期36卷 1941-1949页

作者： yu xiaoping GUO Yafei DENG Tianlong Tianjin Key Laboratory of Marine Resources and Chemistry College of Chemical Engineering and Materials ScienceTianjin University of Science and Technology College of Chemistry and Materials Science Northwest University

In order to identify the effects of seasonal variation on the migration and transformation of antimony species at the sediment-water interface of the Poyang Lake, the largest fresh lake in China, a simulation study was carried out in the laboratory. Antimony species including antimonite Sb(III), antimonate Sb(V) and the fraction of organic forms(Sb-org) in overlying water at different temperatures were regularly measured during the simulation period. Different bound antimony forms in sediments were also determined along with the different antimony species in porewaters after the simulation terminated. The results indicated that temperature change during seasonal alternation plays an important role in the migration and transformation behavior of antimony at the sediment-water interface of the Poyang Lake. Antimony species both in porewaters and overlying water were sensitive to the variation of temperature, especially the Sb-org species. Antimony migrates from porewaters to the overlying water when the temperature decreases, and meanwhile the equilibrium between Sb(III) and Sb(V) in porewaters shifts toward Sb(V) when the temperature increases during seasonal alternation. Although temperature had less influence on the antimony species in sediments than in porewaters or in the overlying water, the average content of each antimony species in sediments increased with the decrease of temperature, suggesting that the decrease of temperature causes enrichment of antimony in the sediment.

关键词： geochemistry antimony species seasonal variation Poyang Lake

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Thermal Characteristics of Room Temperature Inorganic Phase Change System Containing Calcium Chloride

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Chemical Research in Chinese Universities 2015年第3期31卷 452-456页

作者： GAO Daolin GUO Yafei yu xiaoping WANG Shiqiang DENG Tianlong Tianjin Key Laboratory of Marine Resources and Chemistry College of Marine Science and EngineeringTianjin University of Science and Technology Tianjin 300457 P.R.China

A novel inorganic calcium-based phase change material（PCM-Ca） consisted of 47.1%（mass fraction） water, 47.7% calcium chloride, 2% potassium nitrate, 2% potassium bromide and 1.2% strontium chloride with a solid-liquid phase change temperature of 21.4 ℃ was investigated systematically. Among the components of PCM-Ca, calcium chloride and water act as the latent heat storage materials, and potassium nitrate, potassium bromide and strontium chloride work as the modifier, thickener and nucleating agent, respectively. Thermochemical properties including melting point, latent heat, density and thermal conductivity of the PCM-Ca were measured experimentally. The experimental results indicate that the melting latent heat, thermal conductivity at the melting point and density at room temperature for the PCM-Ca are 203.3 kJ/kg, 1.3637 W·m-1·K-l and 1.55×103 kg/m3, respectively. Moreover, a thirty-run-cycling test showed that the PCM-Ca has a good thermal characteristic with no phase segregation or supercooling, and the maximum deviations of latent heat and phase change temperature are only 0.2% and 1.6%, respectively.

关键词： Phase change material Calcium chloride Latent heat Thermal conductivity

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The life-history trait trade-offs mediated by reproduction and immunity in the brown planthopper,Nilaparvata lugens Stål

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Journal of Integrative Agriculture 2024年第6期23卷 2018-2032页

作者： Dan Sun Hongfeng Wang Jiahui Zeng Qiuchen Xu Mingyun Wang xiaoping yu Xuping Shentu Zhejiang Provincial Key Laboratory of Biometrology and Inspection&Quarantine College of Life ScienceChina Jiliang UniversityHangzhou 310018China

Reproduction and immune defense are costly functions,and they are expected to tradeoff with each other to drive *** brown planthopper(BPH),Nilaparvata lugens Stål(Hemiptera,Delphacidae),is a global superpest that mostly damages rice ***-like symbionts(YLS)exist in the abdominal fat body tissue and are tightly associated with the development,growth,and reproduction of *** previous research demonstrated that mating behavior promotes the release of YLS from the fat body into the hemolymph in the BPH,thereby triggering an immune ***,the fitness costs related to life-history traits of BPH(such as survival rate)have a strong dependence on the relative abundance of ***,the possible relationship between reproduction and the immune response in BPH has not been *** this study,an omics-based approach was used to analyze the transcriptome of fat body tissues in mated and unmated BPH at 72 h post-eclosion,from which two antimicrobial peptide genes,NlDefensin A(NlDfA)and NlDefensin B(NlDfB),were selected since they were highly expressed in mated ***,the full-length cDNA sequences of the NlDfA and NlDfB genes were cloned and *** results showed up-regulation of the NlDfA and NlDfB genes in mated BPH when compared to unmated ***-temporal expression analysis indicated that the NlDfA and NlDfB genes were expressed in all tissues and developmental stages,and they were most highly expressed in the fat body at 24 h ***,the symbionts in BPH were significantly inhibited by the in vitro expression of the NlDfA and NlDfB ***,RNA interference(RNAi)-mediated suppression of NlDfA and NlDfB dramatically increased the relative abundance of YLS in the fat body,while YLS in the hemolymph decreased *** BPHs also displayed some fitness disadvantages in survival,fecundity,hatchability,and possibly the vertical transmission of YLS from hemolymph to *** results

关键词： Nilaparvata lugens reproduction immune defense trade-off

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Seasonal variations of phosphorus species in the Tuohe River, China. Part Ⅰ. Sediments

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Journal of Oceanology and Limnology 2018年第6期36卷 1950-1961页

作者： XU Qing yu xiaoping GUO Yafei DENG Tianlong Tianjin Key Laboratory of Marine Resources and Chemistry College of Chemical Engineering and Materials ScienceTianjin University of Sciences and EngineeringTianjin 300457China School of Architecture and Civil Engineering Chengdu UniversityChengdu 610106China Department of Chemistry and Biochemistry Laurentian UniversitySudburyOntarioP3E 2C6Canada

Sediment cores were collected at an upstream site(Jintang) and a downstream site(Neijiang) in summer and winter in the Tuohe River, which is one of the five largest tributaries of the Changjiang(Yangtze) River in China. A sequential leaching procedure was applied to determine the concentrations of the different forms of solid phosphorus, including exchangeable phosphorus(Exc-P) as well as phosphorus associated with iron oxides(Fe-P), with aluminum oxides(Al-P), with apatite(Ca-P) and with the residual fraction(Res-P), as correlated with water content and total organic carbon. The seasonal variations and the vertical distributions of phosphorus species in sediments at both sampling sites demonstrated that: 1) total phosphorus(TP) in summer and winter were ranged between 1 313–2 330, 1 491–2 228 mg/kg in Jintang and 543–2 128, 603–1 175 mg/kg in Neijiang, respectively. It can predicated the pollution of TP in Jintang is serious than that in Neijiang both in summer and winter; 2) total inorganic phosphorus(TIP) was the dominant form of TP; 3) Ca-P was the main chemical forms of TIP in the sediments. Based on the profiles in sediments and bio-available phosphorus data, it revealed that bio-available phosphorus(BAP) represented only a minor portion(0.61%–3.59%) of TP, and the vertical distribution of soluble reactive phosphorus(SRP) in corresponding porewaters was more abundant in the upper layer of the sediment, which suggests that BAP may be converted to non-bioavailable phosphorus in deeper layer of the sediment of this dynamic system.

关键词： phosphorus species vertical distribution seasonal variation Tuohe River

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Can we reestablish a self-sustaining population?A case study on reintroduced Crested Ibis with population viability analysis

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Avian Research 2021年第2期12卷 131-140页

作者： Yashuai Zhan Fang Wang Zhenxia Cui Min Li Xia Li Xinping Ye xiaoping yu College of Life Sciences Shaanxi Normal UniversityXi’an 710119China Reintroduction Center of Crested Ibis Ningshan CountyAn’kang 725000China

Background:One of the most challenging tasks in wildlife conservation and management is clarifying which and how external and intrinsic factors influence wildlife demography and long-term *** wild population of the Crested Ibis(Nipponia nippon)has recovered to approximately 4400,and several reintroduction programs have been carried out in China,Japan and *** viability analysis on this endangered species has been limited to the wild population,showing that the long-term population growth is restricted by the carrying capacity and ***,gaps in knowledge of the viability of the reintroduced population and its drivers in the release environment impede the identification of the most effective population-level priorities for aiding in species ***:The field monitoring data were collected from a reintroduced Crested Ibis population in Ningshan,China from 2007 to *** individual-based VORTEX model(Version 10.***.5.0)was used to predict the future viability of the reintroduced population by incorporating adaptive patterns of ibis movement in relation to catastrophe frequency,mortality and sex ***:The reintroduced population in Ningshan County is unlikely to go extinct in the next 50 *** popula-tion size was estimated to be 367,and the population genetic diversity was estimated to be *** analysis showed that population size and extinction probability were dependent on the carrying capacity and sex *** carrying capacity is the main factor accounting for the population size and genetic diversity,while the sex ratio is the primary factor responsible for the population growth ***:A viable population of the Crested Ibis can be established according to population viability *** on our results,conservation management should prioritize a balanced sex ratio,high-quality habitat and low mortality.

关键词： Carrying capacity Nipponia nippon Population viability analysis Reintroduction Sex ratio VORTEX model

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Effects of breeding success,age and sex on breeding dispersal of a reintroduced population of the Crested Ibis(Nipponia nippon)in Ningshan County,China

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Avian Research 2018年第4期9卷 314-320页

作者： Rong Dong Xinping Ye Lin Zhong Xia Li Min Li Huaqiang Wang xiaoping yu College of Life Sciences Shaanxi Normal UniversityXi’an 710119China Research Center for UAV Remote Sensing Shaanxi Normal UniversityXi’an 710119China Shaanxi Nature Reserve and Wildlife Management Xi’an 710082China Reintroduction Center of Crested Ibis Ningshan CountyAn’kang 725000China Wildlife Administration of Yaozhou Forestry Bureau Tong Chuan 727110China

Background: Breeding dispersal is an important ecological process that affects species' population dynamics and colonization of new suitable areas. Knowledge of the causes and consequences of breeding dispersal is fundamental to our understanding of avian ecology and evolution. Although breeding success for a wild and reintroduced population of the Crested Ibis(Nipponia nippon) has been reported, the relationships between individuals' breeding dispersal and their breeding success, age and sex remain ***: Ibises' breeding dispersal distance, which is the distance moved by adults between sites of reproduction, was estimated based on the observations of consecutive breeding sites of marked ibis individuals. From observational and capture-recapture data(n as = 102) over 9 years, individuals' breeding dispersal probability in relation to age, sex, and reproductive success wanalyzed via a generalized linear mixed effect modeling ***: Our results show that 55% males and 51% females keep their previous territories following nesting success. Failed breeding attempts increased dispersal probabilities. Both females and males failed in breeding were more likely to disperse with greater distances than successful birds(females: 825 ± 216 m vs 196 ± 101 m, males: 372 Crested Ibis exhibited a female-biased dispersal pattern that the mean dispersal distance± 164 m vs 210 ± 127 m). of females(435 ± 234 m) was much larger than that of males(294 ± 172 m).Conclusion: Our results are fundamental to predict the patterns of breeding dispersal related to reproductive success under different release sites. From the conservation point of view, landscape connectivity between the reintroduced populations should be taken into account in accordance with the distance of breeding dispersal.

关键词： Breeding dispersal Breeding success Generalized linear mixed effect model Crested Ibis Reintroduced population

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