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Maternal Anxiety 16 Months after the Great East Japan Earthquake Disaster Area: First Report

Health 2014年第10期6卷 870-878页

作者： Hatsumi yoshii Hidemitsu Saito Saya Kikuchi Takashi Ueno Kineko Sato Department of Psychiatry Tohoku University Hospital Sendai Japan Division of Clinical Psychology Graduate School of Education Tohoku University Sendai Japan Health Sciences Tohoku University Graduate School of Medicine Miyagi Japan

The Great East Japan Earthquake, a magnitude 9.0 quake that occurred on March 11, 2011, left more than 20,000 killed or missing and resulted in more than 400,000 people being displaced. The Fukushima Nuclear Power Plant accident released large amounts of radioactive material into the air. Among the victims of this combined disaster were many pregnant and parturient women, and this study aimed to determine post-disaster anxiety among this specific population and measures for the future. Participants were 259 women (mean age 33.02 ± 4.79 years) who gave birth around the time of the earthquake in Miyagi Prefecture, one of the disaster areas. Sixteen months after the earthquake, we administered survey questionnaires on anxiety. We transcribed questionnaire responses, coded raw data by context, and categorized these codes by commonality. After extracting subcategories of anxiety-related factors, we categorized them into more abstract concepts. Among the participants, 126 (48.6%) reported having no available professionals with whom they could consult about childrearing. Participants reported anxiety in the following 12 categories: “radiation,” “child’s physical and mental growth/development,” “recurrence of earthquake and tsunami,” “financial issues,” “childrearing environment,” “living environment,” “maternal employment,” “stigma,” “familial issues,” “maternal health,” “childrearing,” and “the future”. A beneficial way to reduce maternal anxiety in the 12 areas identified would be to develop support systems that provide continuous support for children’s mental health care needs, psychological guidance, community support for maternal empowerment, outreach for individual support, and professional consultation for mothers who have high anxiety about radioactivity.

关键词： Earthquake Maternal Anxiety Child Care Disaster Area

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Management of the late effects of disconnected pancreatic duct syndrome: A case report

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World Journal of Clinical Cases 2019年第9期7卷 1053-1059页

作者： Reiko Yamada Yuhei Umeda Yasunori Shiono Hiroaki Okuse Naoki Kuroda Junya Tsuboi Hiroyuki Inoue Yasuhiko Hamada Kyosuke Tanaka noriyuki Horiki Yoshiyuki Takei Department of Gastroenterology and Hepatology Mie University Graduate School of Medicine Department of Endoscopy Mie University Graduate School of Medicine

BACKGROUND There have been few reports about the late effects of disconnected pancreatic duct syndrome(DPDS). Although few reports have described the recurrence interval of pancreatitis, it might be rare for recurrence to occur more than 5 years ***, we describe a case of recurrence in an 81-year-old man after the treatment of walled-off necrosis(WON) with pancreatic transection 7 years *** SUMMARY An 81-year-old man visited our hospital with chief complaints of fever and abdominal pain 7 years after the onset of WON due to severe necrotic pancreatitis. His medical history included an abdominal aortic aneurysm(AAA),hypertension, dyslipidemia, and chronic kidney disease. Computed tomography(CT) scan showed that the pancreatic fluid collection(PFC) had spread to the aorta with inflammation surrounding it, and CT findings suggested that bleeding occurred from the vasodilation due to splenic vein occlusion. First, we attempted to perform transpapillary drainage because of venous dilation around the residual stomach and the PFC. However, pancreatic duct drainage failed because of complete main pancreatic duct disruption. Second, we performed endoscopic ultrasound-guided drainage. After transmural drainage, the inflammation improved and stenting for the AAA was performed successfully. The inflammation was resolved, and he has been free from infection for more than 2 years after the *** This case highlights the importance of continued follow-up of patients for recurrence after the treatment of WON with pancreatic transection.

关键词： Case report Endoscopy Necrosis Pancreas Walled-off necrosis Disconnected pancreatic duct syndrome

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Social distance toward schizophrenia among parents of adolescents

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Health 2012年第7期4卷 386-391页

作者： Hatsumi yoshii Yuichiro Watanabe Hideaki Kitamura Yiwei Ling Kouhei Akazawa Department of Medical Informatics and Statistics Graduate School of Medicine Niigata University Niigata Japan Department of Psychiatry Niigata University Graduate School of Medical and Dental Sciences Niigata Japan Department of Psychiatry Niigata University Graduate School of Medical and Dental Sciences Niigata Japan Division of Medical Education Comprehensive Medical Education Center School of Medicine Faculty of Medicine Niigata University Niigata Japan School of Health Sciences Faculty of Medicine Tohoku University Miyagi Japan

Social distance toward schizophrenia is a reason for delays in receiving early treatment for the disorder. This study attempted to identify the factors underlying social distance. The participants were 2690 parents of adolescents. Factor analysis using a social distance scale identified two factors: private relationship and social relationship. Regression analysis revealed that gender, age, and participation in welfare activities for people with mental illnesses had independent effects on the factor private relationship (p < 0.05). These results suggest that women aged 40 - 49 years should be targeted for activities that attempt to counteract social distance and that they would benefit from taking part in public welfare activities for individuals with mental illnesses.

关键词： Schizophrenia Social Distance Parents of Adolescents

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Direct Production of High Pressure Hydrogen at Great Rate from Glycerol/Water/Metal Mixture

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Green and Sustainable Chemistry 2016年第3期6卷 136-142页

作者： Seiichi Deguchi Norifumi Isu noriyuki Kobayashi Hajime Ohtani Department of Energy Engineering and Science Nagoya University Nagoya Japan Kitchen and Bathroom Technology Research Institute LIXIL Corporation Tokoname Japan Department of Chemical Engineering Nagoya University Nagoya Japan Department of Life Science and Applied Chemistry Nagoya Institute of Technology Nagoya Japan

One of the key issues facing the global society today is to find renewable and sustainable energy sources. Hydrogen has gained much attention in recent years since it is one of fuels for fuel cells. It emits no carbon dioxide when it is used and so on. In this study, a great rate production of high pressure hydrogen rich gas from glycerol/water/metal mixtures was developed since glycerol has become one of the enormous industrial by-products, especially from biodiesel processing plants. It was found that cobalt was the optimum metal additive among tested metals of aluminum, cobalt, magnesium and nickel in terms of a hydrogen producing rate, a hydrogen partial pressure and a conversion ratio from 50 mol% glycerol/water mixtures under an operating temperature of 723 K. Concretely, hydrogen rich gas with concentration about 64%H2 and high partial pressure about 4 MPaN,H2 could be produced at the great producing rate of 42.9 LN,H2 dm-2min-1 and high conversion ratio about 60%H2. All the produced hydrogen rich gases from glycerol/water/metal mixtures were by no means inferior to pure hydrogen as a fuel for the polymer elec-trolyte fuel cell.

关键词： Great-Rate Hydrogen Production High Pressure Hydrogen Glycerol Reforming Sustainable Energy

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BEACH-Domain Proteins Act Together in a Cascade to Mediate Vacuolar Protein Trafficking and Disease Resistance in Arabidopsis

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Molecular Plant 2015年第3期8卷 389-398页

作者： Ooi-kock Teh noriyuki Hatsugai Kentaro Tamura Kentaro Fuji Ryo Tabata Katsushi Yamaguch Shuji Shingenobu Masashi Yamada Mitsuyasu Hasebe Shinichiro Sawa Tomoo Shimada Ikuko Hara-Nishimura Graduate School of Science Kyoto University Sakyo-ku Kyoto 606-8502 Japan Research Centre for Cooperative Projects Hokkaido University Kita-ku Sapporo 060-8638 Japan Graduate School of Science and Technology Kumamoto University Kumamoto 860-8555 Japan Functional Genomics Facility National Institute for Basic Biology Okazaki 444-8585 Japan Department of Biology and IGSP Center for Systems Biology Duke University Durham NC 27708 USA Division of Evolutionary Biology National Institute for Basic Biology Okazaki 444-8585 Japan School of Life Science The Graduate University for Advanced Studies Okazaki 444-8585 Japan Present address: Department of Plant Biology and Forest Genetics Uppsala BioCenter Swedish University of Agricultural Sciences (SLU) and Linnean Centre ofPlant Biology Uppsala SE-75007 Sweden present address: Microbial and Plant Genomics Institute University of Minnesota St Paul MN 55108 USA Present address: RIKEN Innovation Center RIKEN 2-1 Hirosawa Wako Saitama 351-0198 Japan

Membrane trafficking to the protein storage vacuole （PSV） is a specialized process in seed plants. However, this trafficking mechanism to PSV is poorly understood. Here, we show that three types of Beige and Chediak-Higashi （BEACH）-domain proteins contribute to both vacuolar protein transport and effector- triggered immunity （ETI）. We screened a green fluorescent seed （GFS） library of Arabidopsis mutants with defects in vesicle trafficking and isolated two allelic mutants gfs3 and gfs12 with a defect in seed pro- tein transport to PSV. The gene responsible for the mutant phenotype was found to encode a putative pro- tein belonging to group D of BEACH-domain proteins, which possess kinase domains. Disruption of other BEACH-encoding loci in the gfs12 mutant showed that BEACH homologs acted in a cascading manner for PSV trafficking. The epistatic genetic interactions observed among BEACH homologs were also found in the ETI responses of the gfs12 and gfs12 bchb-1 mutants, which showed elevated avirulent bacterial growth. The GFS12 kinase domain interacted specifically with the pleckstrin homology domain of BchCl. These results suggest that a cascade of multiple BEACH-domain proteins contributes to vacuolar protein transport and plant defense.

关键词： BEACH-domain protein Arabidopsis thaliana vacuolar protein transport protein storage vacuoles,plant immunity

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Transformation of atmospheric tritium in the environment

Transformation of atmospheric tritium in the environment

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3rd China-Japan Workshop on the Tritium and Breeding Blanket Technology Program Guide

作者： noriyuki Momoshima Shinji Sugihara Radioisotope center Kyushu UniversityHakozakiHigashi-kuFukuoka 812-8581Japan

Three chemical forms of tritium has been observed in the atmosphere,those are tritiated water (HTO),elemental tritium(HT) and tritiated hydrocarbons(CHT).The concentrations of these chemical species are not so different,distributing from a few mBq/m to at most a few tens mBq/***,a significant difference are observed in their specific activities(T/H),ranging 3 orders of *** HT has the highest specific activity followed by *** specific activity of HTO is lowest among them and comparable to that of environmental *** enrichment mechanism of tritium to hydrogen(H) and methane(CH) is reported in the environment,suggesting HT and CHT probably coming from artificial sources.

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Large Scale Classical MD for Nano-Indentation

Large Scale Classical MD for Nano-Indentation

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The Sixth World Congress on Computational Mechanics in Conjunction with the Second Asian-Pacific Congress on Computational MechanicsⅠ

作者： Kenji Nishimura noriyuki Miyazaki Research Institute for Computational Sciences (RICS) Research Institute of Advanced Industrial Science and Technology (AIST) Tsukuba Central 2 Tsukuba 305-8568 Japan Department of Chemical Engineering Kyushu University 6-10-1 Hakozaki Higashi-ku Fukuoka 812-8581

Nanoindentation method is applied to examine the mechanical properties of materials such as elastic and plastic deformation, fracture and friction. However, although the method has potential applications to determine nanoscale mechanical properties of small areas and thin films, the atomic scale mechanisms underlying the method are not well understood. In order to clarify the mechanisms, atomic scale simulations such as molecular dynamics have been carried out. The molecular dynamics simulations indicated that dislocation loops are nucleated under an indenter and glide on the slip plane, then dislocation structures due to dislocation interactions and the cross slip are formed in single crystalline metals [1,2]. Moreover, the influence of grain boundaries on the plastic deformation process in nanocrystalline metals [3] and the deformation process of ceramic materials [4] under nanoindentation were reported. In this study, we examine the initial stage of plastic deformation in nanoindentation process in a thin iron film using a molecular dynamics simulation. A rigid knife-like indenter is used in the simulation. We obtain a load-displacement curve under the action of an indenter. When the displacement of the indenter exceeds a yield point, the nucleation of dislocation loops is observed below the surface contacting with indenter sides. Then the Lomer-Cottrell reaction between the dislocation loops occurs directly beneath the indenter. In addition, new dislocation generated by the Lomer-Cottrell reaction moves in a different slip plane together with double kink formation with increasing the displacement and finally is separated into two dislocations.

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Crystal Structure Study on Non-Coplanarly Organized Accumulating Aromatic Rings Molecules: Spatial Organization of C,C,N-Triaryl Substituted Imines

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Crystal Structure Theory and Applications 2013年第4期2卷 139-147页

作者： Akiko Okamoto Atsushi Nagasawa Siqingaowa noriyuki Yonezawa Department of Organic and Polymer Materials Chemistry Tokyo University of Agriculture and Technology Tokyo Japan

The X-ray crystal structures of C,C,N-triaryl-substituted imine compounds, which have methoxy or hydroxy group adjacent to the imino moiety, are reported and discussed in comparison with those of the precursor ketone compounds, 1-(4-chlorobenzoyl)-2,7-dimethoxynaphthalene and 1-(4-chlorobenzoyl)-2-hydroxy-7-methoxynaphthalene. In crystals, three aromatic rings in a molecule of the methyl ether-retained imine compound are positioned almost perpendicularly to each other by giving non-coplanar spatial organization of the single molecular structure [dihedral angles: 85.32(18)° for C-linked phenyl ring and naphthalene ring;79.27(17)° for N-linked phenyl ring and naphthalene ring;84.78(17)° for C-linked phenyl ring and N-linked phenyl ring]. Spatial organization of the analogous methyl ether-cleaved imine compound has essentially same topology [dihedral angles 80.39(6)° for the C-linked phenyl ring and naphthalene ring;82.35(6)° for the N-linked phenyl ring and naphthalene ring;87.09(7)° for C- and N-linked phenyl rings]. These structural features of triarylimines apparently differ from those of the precursor ketones. Two aromatic rings in the methyl ether-cleaved ketone compound make smaller dihedral angle [58.10(6)°] by intramolecular hydrogen bond between ketonic carbonyl group and hydroxy group [2.5573(16) A] than that of the methyl ether-retained ketone [72.06(7)°]. In molecular packing, the methyl ether-retained imine forms tubular molecular alignments composed of R—S dimeric molecular pairs, whereas the methyl ether-retained ketone affords consecutively stacks of one configurated molecules.

关键词： Non-Coplanarly Accumulated Aromatic Rings Spatial Organization Triarylimine

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Association of social distance toward schizophrenia with help-seeking among mothers of adolescents in Japan

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Health 2012年第12期4卷 1346-1351页

作者： Hatsumi yoshii Yuichiro Watanabe Hideaki Kitamura Atiqul Haq Mazumder Kouhei Akazawa Department of Medical Informatics and Statistics Niigata University Graduate School of Medicine Niigata Japan Department of Psychiatry Niigata University Graduate School of Medical and Dental Sciences Niigata Japan National Institute of Mental Health Dhaka Bangladesh School of Health Sciences Faculty of Medicine Tohoku University Sendai Japan

Negative maternal attitudes toward schizophrenia may be linked with delayed treatment of their children. We investigated the relation between negative attitudes toward schizophrenia and help-seeking among mothers of junior and senior high school students in Japan. The participants were 1309 Japanese mothers of junior and senior high school students. Social distance was evaluated by using the Social Distance Scale-Japanese version (SDS-J). In addition, mothers were asked about help-seeking for a child with sleeplessness, social withdrawal, and strange behavior. One-way analysis of variance and Student’s t-test were used to evaluate associations between social distance toward schizophrenia and help-seeking. Most (76.4%) participants were aged 40 - 49 years. Maternal demographic characteristics significantly associated with social distance were employment and participation in welfare activities for people with mental illness. In responding to a child with sleeplessness, social withdrawal, and strange behavior, the level of maternal social distance was not significantly associated with the likelyhood of seeking psychiatric help. However, mothers with greater social distance were less likely to seek help at a psychiatric clinic. Maternal social distance toward schizophrenia was not significantly associated with seeking psychiatric help;however, it did affect the type of facility selected among those would seek such help.

关键词： Social distance Schizophrenia Help-Seeking Mothers Adolescence

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Assessment of Regional Dietary Exposure to Dioxins in Seafood in Japan

Assessment of Regional Dietary Exposure to Dioxins in Seafoo...

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首届风险分析与危机反应国际学术研讨会

作者： noriyuki Suzuki Takeo Sakurai National Institute for Environmental Studies 16-2 OnogawaTsukubaIbaraki305-8506Japan National Institute for Environmental Studies 16-2 OnogawaTsukubaIbaraki305-8506Japan

＜正＞This paper presents a method of estimating dietary exposure to dioxins in specific region from monitoring data of dioxins concentration in seafood by catching area and information of seafood ***- Carlo method was applied to take into account both the uncertainty of measured value of dioxins levels in fishes and variability between fish *** seafood circulation was simulated with a linear programming （LP） *** exposure to dioxins in seafood in seven regions in Japan was estimated and compared with the results of Total Dietary Studies （TDS）.No significant geographical variability of dietary exposure to dioxins in seafood was observed for general population in Japan.

关键词： Seafood Dioxins Regional dietary exposure Monte-Carlo analysis

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