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Petroleum Science 2024年第2期21卷 1171-1189页

作者： Kun-Peng Zhang Mian Chen Chang-Jun Zhao Su Wang yong-Dong fan State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing102249China MOE Key Laboratory of Petroleum Engineering in China University of Petroleum Beijing102249China Beijing International Center for Gas Hydrate School of Earth and Space SciencesPeking UniversityBeijing100871China

A method for in-situ stress measurement via fiber optics was proposed. The method utilizes the relationship between rock mass elastic parameters and in-situ stress. The approach offers the advantage of long-term stress measurements with high spatial resolution and frequency, significantly enhancing the ability to measure in-situ stress. The sensing casing, spirally wrapped with fiber optic, is cemented into the formation to establish a formation sensing nerve. Injecting fluid into the casing generates strain disturbance, establishing the relationship between rock mass properties and treatment ***, an optimization algorithm is established to invert the elastic parameters of formation via fiber optic strains. In the first part of this paper series, we established the theoretical basis for the inverse differential strain analysis method for in-situ stress measurement, which was subsequently verified using an analytical model. This paper is the fundamental basis for the inverse differential strain analysis method.

关键词： In-situ stress Fiber optic Orthotropic elastic Differential evolution ABAQUS

Predictive value of NLR, Fib4, and APRI in the occurrence of liver failure after hepatectomy in patients with hepatocellular carcinoma

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 155-165页

作者： Tian-Zuo Kuang Meng Xiao yong-fan Liu Department of Hepatobiliary Surgery Ji’an Central People’s HospitalJi’an 343000Jiangxi ProvinceChina

BACKGROUND Neutrophil-lymphocyte ratio(NLR),fibrosis index based on four factors(Fib4),aspartate aminotransferase-to-platelet ratio index(APRI)can be used for prognostic evaluation of hepatocellular ***,no study has established an individualized prediction model for the prognosis of hepatocellular carcinoma based on these *** To screen the factors that affect the prognosis of hepatocellular carcinoma and establish a nomogram model that predicts postoperative liver failure after hepatic resection in patients with hepatocellular *** In total,220 patients with hepatocellular carcinoma treated in our hospital from January 2022 to January 2023 were *** were divided into 154 participants in the modeling cohort,and 66 in the validation *** analysis of the changes in NLR,Fib4,and APRI levels in 154 patients with hepatocellular carcinoma before liver resection and at 3 mo,6 mo,and 12 mo postoperatively was *** logistic regression to analyze the influencing factors on the occurrence of liver failure in hepatocellular carcinoma patients,roadmap prediction modeling,and validation,patient work characteristic curves(ROCs)to evaluate the predictive efficacy of the model,calibration curves to assess the consistency,and decision curve analysis(DCA)to evaluate the model’s validity were also *** Binary logistic regression showed that Child-Pugh grading,Surgical site,NLR,Fib4,and APRI were all risk factors for liver failure after hepatic resection in patients with hepatocellular *** modeling cohort built a column-line graph model,and the area under the ROC curve was 0.986[95%confidence in terval(CI):0.963-1.000].The patients in the validation cohort utilized the column-line graph to predict the probability of survival in the validation cohort and plotted the ROC curve with an area under the curve of the model of 0.692(95%CI:0.548-0.837).The deviation of the actual outcome curves from the c

关键词： Hepatocellular carcinoma Hepatic resection Liver failure Influencing factors Columnar graphs

High Speed Sintering:Assessing the Influence of Energy Input on Microstructure and Mechanical Properties of Polyether Block Amide(PEBA)Parts

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Chinese Journal of Polymer Science 2024年第5期42卷 675-682,I0004,I0010页

作者： Jiang-Tao Sun Zhi-yong fan Yi-Wei Mao Wei Li Wei Zhu Dao-Sheng Cai Qing-Song Wei State Key Laboratory of Materials Processing and Die&Mould Technology Huazhong University of Science and TechnologyWuhan430074China State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan430074China National Engineering Research Centre for High Efficiency Grinding Hunan UniversityChangsha410082China Wuhan EasyMFG Technology CO. LTDWuhan430074China

High speed sintering,a new powder-bed fusion additive manufacturing technology,utilizes infrared lights(IR)to intensely heat and melt polymer *** presence of defects such as porosity,which is associated with particle coalescence,is highly dependdent on the level of energy *** study investigate the influcence of energy input on porosity and its subsequent effects on the mechanical properties and microstructures of PEBA *** parts were manufactured with a variety of lamp powers,resulting in a range of energy input levels spanning from low to ***,they underwent testing using Archimedes’method,followed by tensile *** porosity,mechanical characteristics,and energy input exhibit a strong correlation;inadequate energy input was the primary cause of pore *** the reduced IR light power resulted in the following outcomes:porosity,ultimate tensile strength,and elongation of 1.37%,7.6 MPa,and 194.2%,*** the energy input was further increased,the porosity was reduced to as low as 0.05%and the ultimate tensile strength and elongation were increased to their peak values of 233.8%and 9.1 MPa,respectively.

关键词： High speed sintering Additive manufacturing Energy input Powder bed fusion PEBA

Machine learning for carbonate formation drilling: Mud loss prediction using seismic attributes and mud loss records

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Petroleum Science 2024年第2期21卷 1241-1256页

作者： Hui-Wen Pang Han-Qing Wang Yi-Tian Xiao Yan Jin Yun-Hu Lu yong-Dong fan Zhen Nie National Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing102249China College of Science China University of Petroleum-BeijingBeijing102249China Petroleum Exploration and Production Research Institute SINOPECBeijing102206China College of Petroleum Engineering China University of Petroleum-BeijingBeijing102249China Research Institute of Petroleum Exploration and Development CNPCBeijing100083China

Due to the complexity and variability of carbonate formation leakage zones, lost circulation prediction and control is one of the major challenges of carbonate drilling. It raises well-control risks and production expenses. This research utilizes the H oilfield as an example, employs seismic features to analyze mud loss prediction, and produces a complete set of pre-drilling mud loss prediction solutions. Firstly, 16seismic attributes are calculated based on the post-stack seismic data, and the mud loss rate per unit footage is specified. The sample set is constructed by extracting each attribute from the seismic trace surrounding 15 typical wells, with a ratio of 8:2 between the training set and the test set. With the calibration results for mud loss rate per unit footage, the nonlinear mapping relationship between seismic attributes and mud loss rate per unit size is established using the mixed density network ***, the influence of the number of sub-Gausses and the uncertainty coefficient on the model's prediction is evaluated. Finally, the model is used in conjunction with downhole drilling conditions to assess the risk of mud loss in various layers and along the wellbore trajectory. The study demonstrates that the mean relative errors of the model for training data and test data are 6.9% and 7.5%, respectively, and that R2is 90% and 88%, respectively, for training data and test data. The accuracy and efficacy of mud loss prediction may be greatly enhanced by combining 16 seismic attributes with the mud loss rate per unit footage and applying machine learning methods. The mud loss prediction model based on the MDN model can not only predict the mud loss rate but also objectively evaluate the prediction based on the quality of the data and the model.

关键词： Lost circulation Risk prediction Machine learning Seismic attributes Mud loss records

Current Status of Clinical Application and Basic Research on Draba nemerosa Hebecarpa Jujube Lung-Diarrhoea Soup

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Journal of Biosciences and Medicines 2024年第5期12卷 144-153页

作者： yong fan Department of Traditional Chinese Medicine College of Medicine Qinghai University Xining China

The clinical application and basic research of Draba nemerosa Hebecarpa jujube diarrhoea lung soup focus on respiratory diseases and circulatory diseases, and its clinical application is more compared with the basic research, and Draba nemerosa Hebecarpa jujube diarrhoea lung soup is mostly used in the form of “Draba nemerosa Hebecarpa Hebecarpa jujube diarrhoea lung soup with additional subtractions or other formulas combining Draba nemerosa Hebecarpa Hebecarpa Hebecarpa jujube diarrhoea lung soup” in the clinical application. This article will focus on the main mechanisms of Draba nemerosa Hebecarpa jujube diarrhoea lung soup and its main components in the treatment of respiratory and circulatory diseases, and will give a review of the basic research on Draba nemerosa Hebecarpa Hebecarpa jujube diarrhoea lung soup as follows.

关键词： Draba nemerosa Hebecarpa Jujube Laxative Lung Soup Clinical Application Basic Research

L-Type Calcium Channel Modulates Low-Intensity Pulsed Ultrasound-Induced Excitation in Cultured Hippocampal Neurons

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Neuroscience Bulletin 2024年第7期40卷 921-936页

作者： Wen-yong fan Yi-Ming Chen Yi-fan Wang Yu-Qi Wang Jia-Qi Hu Wen-Xu Tang Yi Feng Qian Cheng Lei Xue State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Fudan UniversityShanghai 200433China Department of Physiology and Neurobiology School of Life SciencesFudan UniversityShanghai 200438China Institute of Acoustics School of Physics Science and EngineeringTongji UniversityShanghai 200092China Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education Tongji UniversityShanghai 200070China Center for Rehabilitation Medicine Department of Pain ManagementZhejiang Provincial People's HospitalAffliated People's HospitalHangzhou Medical CollegeHangzhou 310014China Department of Critical Care Medicine Shanghai General HospitalShanghai Jiaotong University School of MedicineShanghai 200080China Shanghai Research Institute for Intelligent Autonomous Systems Tongji UniversityShanghai 201210China Research Institute of Intelligent Complex Systems Fudan UniversityShanghai 200433China

As a noninvasive technique,ultrasound stimulation is known to modulate neuronal activity both in vitro and in *** latest explanation of this phenomenon is that the acoustic wave can activate the ion channels and further impact the electrophysiological properties of targeted ***,the underlying mechanism of low-intensity pulsed ultrasound(LIPUS)-induced neuro-modulation effects is still ***,we characterize the excitatory effects of LIPUS on spontaneous activity and the intracellular Ca^(2+)homeostasis in cultured hippocampal *** whole-cell patch clamp recording,we found that 15 min of 1-MHz LIPUS boosts the frequency of both spontaneous action potentials and spontaneous excitatory synaptic currents(sEPSCs)and also increases the amplitude of sEPSCs in hippocampal *** phenomenon lasts for>10 min after LIPUS *** with Ca^(2+)imaging,we clarified that LIPUS increases the[Ca^(2+)]cyto level by facilitating L-type Ca^(2+)channels(LTCCs).In addition,due to the[Ca^(2+)]cyto elevation by LIPUS exposure,the Ca^(2+)-dependent CaMKII-CREB pathway can be activated within 30 min to further regulate the gene transcription and protein *** work suggests that LIPUS regulates neuronal activity in a Ca^(2+)-dependent manner via *** may also explain the multi-activation effects of LIPUS beyond *** stimulation potentiates spontaneous neuronal activity by increasing Ca^(2+)influx.

关键词： Low-intensity pulsed ultrasound Neuromodulation L-type calcium channel Hippocampal neuron

县级融媒体中心介入社区民生的服务集成创新路向

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编辑之友 2024年第8期 14-19页

作者：樊拥军河北大学新闻传播学院河北保定071000

县级融媒体中心遵从提供高质量社会服务的原则,回应社区民生日益增长的多样需求,依靠本地资源禀赋,设立专题服务平台,整合联结多方资源,激励从业者主动创新,协同社区党政部门、社会团体、行业服务组织与居民个体共创互利共赢的服务生态... 详细信息

县级融媒体中心遵从提供高质量社会服务的原则,回应社区民生日益增长的多样需求,依靠本地资源禀赋,设立专题服务平台,整合联结多方资源,激励从业者主动创新,协同社区党政部门、社会团体、行业服务组织与居民个体共创互利共赢的服务生态圈,共享集成创新经营收益。在降本增效、提质增量的实践中,县级融媒体不断开发新兴服务业态,推动社区民生事业发展和基层社会长治久安。

关键词：县级融媒体中心集成创新社区民生服务协同寻优

Reshaping the imprinting strategy through the thermo-responsive moiety-derived“deep eutectic solvents”effect

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Chinese Chemical Letters 2024年第1期35卷 441-445页

作者： Huihuang Xiong Yiqun Wan yong fan Mengjia Xu Aiping Yan Yushan Zhang Qifei Jiang Hao Wan State Key Laboratory of Food Science and Technology Nanchang UniversityNanchang 330047China School of Chemistry and Chemical Engineering Nanchang UniversityNanchang 330031China Jiangxi Province Key Laboratory of Modern Analytical Science Nanchang UniversityNanchang 330031China Department of Computer Science University of California IrvineIrvine 92697United States

As a new concept having emerged in last few years,the“deep eutectic solvents”(DESs)effect integrated into the imprinting technology inevitably exposes design limitations of stimuli-responsive molecularly imprinted polymers(MIPs),as well as inadequate analysis of the adsorption performance of ***,a simple yet defined N-isopropylacrylamide/(3-acrylamidopropyl)trimethylammonium chloride(NIPAM/APTMAC)binary DESs system was proposed to prepare intelligent MIPs with ***,magnetic and thermo-responsive MIPs based on functional monomers-derived DESs(TMDESs-MIPs1)were synthesized,revealing DESs effect-regulated affinity/kinetics for the enhanced adsorption capability,eco-friendly thermo-regulated elution for high release efficiency,and simple magnetic separation,along with superior selectivity to rhein(RH)and good regeneration ***-DESs-MIPs1 were utilized to extract RH from Cassiae semen samples coupled with high performance liquid chromatography(HPLC),yielding satisfactory recoveries(79.47%−110.82%)and low limits of detection(LOD)(16.67μg/L).Another two kinds of MIPs adopting the thermo-responsive moiety-derived DESs effect strategy further demonstrated great applicability of such intelligent MIPs for analyses of complicated samples.

关键词： Deep eutectic solvents Molecularly imprinted polymers Magnetic Thermo-responsive Thermo-regulated elution

基于全驱系统方法的高阶严反馈系统时变输出约束控制

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自动化学报 2024年第2期50卷 372-385页

作者：蔡光斌肖永强胡昌华杨小冈凡永华火箭军工程大学导弹工程学院西安710025 西北工业大学航天学院西安710072

针对输出受不对称时变约束的不确定高阶严反馈系统,提出一种基于全驱系统方法的高阶自适应动态面输出约束控制方法.所研究的高阶严反馈系统,每个子系统都是高阶形式,通过非线性转换函数将原输出约束系统转换为新的无约束系统,从而将原... 详细信息

针对输出受不对称时变约束的不确定高阶严反馈系统,提出一种基于全驱系统方法的高阶自适应动态面输出约束控制方法.所研究的高阶严反馈系统,每个子系统都是高阶形式,通过非线性转换函数将原输出约束系统转换为新的无约束系统,从而将原系统输出约束问题转化为新系统输出有界的问题.进一步结合全驱系统方法和自适应动态面控制,直接将每个高阶子系统作为一个整体进行控制器设计,而不需要将其转化为一阶系统形式,有效简化了设计步骤;同时通过引入一系列低通滤波器来获得虚拟控制律的高阶导数,以代替复杂的微分运算.基于Lyapunov稳定性理论证明闭环系统所有信号是一致最终有界的,系统输出在满足约束的条件下能有效跟踪期望的参考信号,且可通过调整参数使得系统跟踪误差收敛到零附近的足够小的邻域内.最后,通过对柔性关节机械臂系统进行仿真,验证了所提出控制方法的有效性.

关键词：全驱系统方法高阶严反馈系统时变输出约束非线性转换函数自适应动态面控制

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关税下调促进了居民分配公平?——基于最惠国不同进口消费品的实证研究

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中央财经大学学报 2024年第2期 15-28页

作者：樊勇田振宇中央财经大学财政税务学院中央财经大学

不断缩小居民收入分配差距是不断提高人民群众获得感、幸福感和安全感的必然要求。本文利用2002—2021年我国31个省份的面板数据,分析了12种进口消费品关税水平的下调对居民收入差距的影响。研究发现,一部分消费品关税下调缓解了收入分... 详细信息

不断缩小居民收入分配差距是不断提高人民群众获得感、幸福感和安全感的必然要求。本文利用2002—2021年我国31个省份的面板数据,分析了12种进口消费品关税水平的下调对居民收入差距的影响。研究发现,一部分消费品关税下调缓解了收入分配不公,关税表现为累退性,一部分消费品关税下调扩大了收入分配差距,关税表现为累进性。因此,对于我国来说,由于不同类型商品属性不同,对居民收入分配的影响也不同,国家政府必须对不同类型商品进口关税实施“分类治理”,针对不同类型商品制定有差异的关税政策才能高效地发挥关税的调节作用,逐渐缩小居民收入分配差距。

关键词：关税收入分配进口消费品