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The crucial role of soil moisture in the evolution of forest cover in Asia since the Last Glacial Maximum

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The Innovation 2024年第3期5卷 9-10页

作者： ying Cheng hongyan Liu School of Geography and Tourism Shaanxi Normal UniversityXi’an 710119China College of Urban and Environmental Sciences and MOE Laboratory for Earth Surface Processes Peking UniversityBeijing 100871China

Forest cover plays a pivotal role in facilitating ecosystem services and climate regulation.In recent decades,much concern has been raised regarding the extent to which forest cover tracks past climate change.Studies at different spatiotemporal scales have revealed significant temporal lags,ranging from decades to millennia,with no consensus reached on this issue.

关键词： forest soil Forest

Catalytic effect of alkali carbonates on CO_2 gasification of Pingshuo coal

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Mining Science and Technology 2011年第4期21卷 587-590页

作者： Meng Lili Wang Meijun Yang Huimin ying hongyan Chang Liping Key Laboratory of Coal Science and Technology Taiyuan University of Technology Taiyuan 030024 China

Na2CO3,Li2CO3,and K2CO3 were used as additives to Pingshuo(PS) coal that was subsequently gasified under a CO2 stream.The catalytic gasification of coal samples by CO2 in the presence single or mixed alkali carbonates was investigated by thermogravimetric analysis.The experimental results indicate that the catalytic effect of Li2CO3 is significantly larger than that of Na2CO3 or K2CO3.The catalytic effect of the mixed,bi-metal carbonate containing Li2CO3 and Na2CO3,or Li2CO3,and K2CO3,is related to the composition of the catalyst and the proportion of the two components.The bi-metal carbonates having a mole ratio of 9:1(Li:X) has the largest catalytic effect for PS coal gasification.A synergistic effect between Li and K,or Na,carbonate appears at temperatures greater than 1300 K.An un-reacted shrinking core model is suitable for kinetic analysis of catalytic gasification of coal samples in the presence of alkali carbonates.It is inappropriate,however,to evaluate the catalytic effect only by the activation energy obtained from the kinetic calculations.

关键词：碱金属碳酸盐催化气化催化效应二氧化碳煤炭催化效果 Na2C03 动力学分析

Key Physical Factors Affecting Spatial-temporal Variation of Labile Organic Carbon Fractions by Biochar Driven in Mollisols Region of Northeast China

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Journal of Northeast Agricultural University(English Edition) 2024年第1期31卷 28-41页

作者： Zhao Wei Liang Fangyuan Liang ying Zhao Hongrui Hao Shuai Wang hongyan Wang Daqing College of Resources and Environment Northeast Agricultural UniversityHarbin 150030China Ulanqab Science and Technology Development Center Ulanqab 012000XinjiangChina Heilongjiang Agricultural Reclamation Economic Research Institute Harbin 150090China

Biochar is widely used to improve soil physical properties and carbon sequestration. However, few studies focuse on the impact of maize stalk biochar on labile organic carbon(LOC) pool and the relationship between physical properties and LOC fractions. A field positioning experiment was performed in Mollisols region of Northeast China to evaluate the influence of maize stalk biochar on the spatial distribution and temporal changes of physical properties and LOC fractions. Maize stalk biochar treatments included C1(1.5 kg·hm^(-2)), C2(3 kg·hm^(-2)), C3(15 kg·hm^(-2)), C4(30 kg·hm^(-2)), and CK(0). The results showed that maize stalk biochar increased soil water contents(SWC) and soil porosity(SP), but reduced bulk density(BD). Maize stalk biochar reduced dissolved organic carbon(DOC) contents in the 0-20 cm soil layer, ranging from 0.25 g·kg^(-1) to 0.31 g·kg^(-1) in harvest period, while increased in the 20-40 cm soil layer. In addition, the application of biochar had a significant impact on the spatial distribution and temporal change of SWC, BD, SP, DOC, hot-water extractable carbon(HWC), acid hydrolyzed organic carbon(AHC Ⅰ, Ⅱ), and readily oxidized organic carbon(ROC). High amounts of maize stalk biochar up-regulated the contents of soil organic carbon SOC, HWC, AHC Ⅰ, AHC Ⅱ, and ROC. In addition, SWC and SP were the key physical factors to affect LOC fractions. In conclusions, maize stalk biochar could improve physical properties, and then influence LOC fractions, and maize stalk biochar could be used as an organic amendment for restoring degraded soils governed by their rates of addition.

关键词： maize stalk biochar labile organic carbon fraction Mollisols region soil physical property dissolved organic carbon

Gene replacement therapy in Bietti crystalline corneoretinal dystrophy:an open-label,single-arm,exploratory trial

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Signal Transduction and Targeted Therapy 2024年第5期9卷 2275-2284页

作者： Jinyuan Wang Jinlu Zhang Shicheng Yu hongyan Li Shaohong Chen Jingting Luo Haibo Wang Yuxia Guan Haihan Zhang Shiyi Yin Huili Wang Heping Li Junle Liu Jingyuan Zhu Qiong Yang ying Sha Chuan Zhang Yuhang Yang Xuan Yang Xifang Zhang Xiuli Zhao Likun Wang Liping Yang Wenbin Wei Beijing Tongren Eye Center Beijing Key Laboratory of Intraocular Tumor Diagnosis and TreatmentBeijing Ophthalmology&Visual Sciences Key LabMedical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information TechnologyBeijing Tongren HospitalCapital Medical University100730 BeijingChina School of Clinical Medicine Tsinghua University100084 BeijingChina Chigenovo Co. Ltd.102206 BeijingChina Department of Ophthalmology Peking University Third HospitalBeijing Key Laboratory of Restoration of Damaged Ocular NervePeking University Third Hospital100191 BeijingChina Department of Ophthalmology The Third People’s Hospital of Dalian116091 DalianChina Department of Biomedical Informatics School of Basic Medical SciencesPeking University Health Science Center100191 BeijingChina Institute of Systems Biomedicine Department of PathologySchool of Basic Medical SciencesPeking University Health Science Center100191 BeijingChina

Bietti crystalline corneoretinal dystrophy is an inherited retinal disease caused by mutations in CYP4V2,which results in blindness in the working-age population,and there is currently no available treatment.Here,we report the results of the first-in-human clinical trial(NCT04722107)of gene therapy for Bietti crystalline corneoretinal dystrophy,including 12 participants who were followed up for 180-365 days.This open-label,single-arm exploratory trial aimed to assess the safety and efficacy of a recombinant adeno-associated-virus-serotype-2/8 vector encoding the human CYP4V2 protein(rAAV2/8-hCYP4V2).Participants received a single unilateral subretinal injection of 7.5×10^(10)vector genomes of rAAV2/8-hCYP4V2.Overall,73 treatment-emergent adverse events were reported,with the majority(98.6%)being of mild or moderate intensity and considered to be procedure-or corticosteroid-related;no treatment-related serious adverse events or local/systemic immune toxicities were observed.Compared with that measured at baseline,77.8%of the treated eyes showed improvement in best-corrected visual acuity(BCVA)on day 180,with a mean±standard deviation increase of 9.0±10.8 letters in the 9 eyes analyzed(p=0.021).By day 365,80%of the treated eyes showed an increase in BCVA,with a mean increase of 11.0±10.6 letters in the 5 eyes assessed(p=0.125).Importantly,the patients’improvement observed using multifocal electroretinogram,microperimetry,and Visual Function Questionnaire-25 further supported the beneficial effects of the treatment.We conclude that the favorable safety profile and visual improvements identified in this trial encourage the continued development of rAAV2/8-hCYP4V2(named ZVS101e).

关键词： cor dystrophy crystalline

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基于变截面复丝模型的机织物模拟

纺织学报 2024年第5期45卷 70-78页

作者：徐辉朱昊潘苏情史红艳应迪绍兴文理学院纺织服装学院浙江绍兴312000 浙江省清洁染整技术研究重点实验室浙江绍兴312000

为解决机织物模拟时因纱线截面不变而导致纱线互相渗透、模拟效果失真等问题,提出一种变截面复丝模型作为机织物模拟时经纬纱的模型。从空间圆参数方程中受到启发,建立空间椭圆参数方程作为纱线的截面模型;提出一种椭圆等分算法,通过等... 详细信息

为解决机织物模拟时因纱线截面不变而导致纱线互相渗透、模拟效果失真等问题,提出一种变截面复丝模型作为机织物模拟时经纬纱的模型。从空间圆参数方程中受到启发,建立空间椭圆参数方程作为纱线的截面模型;提出一种椭圆等分算法,通过等分弧长的方式建立了复丝模型。从受力分析的角度分析纱线中心线上不同位置截面的受挤压程度,建立了平纹及非平纹组织的交织模型,并以压扁系数表示不同截面的压扁状态。研究结果表明:变截面椭圆与复丝相结合构成的经纬纱模型模拟效果逼真;交织模型在减少纱线渗透的同时,也更符合实际情况;模拟的机织物表层纹理清晰,达到了预期效果。

关键词：空间椭圆变截面复丝模型交织模型机织物模拟经纬纱模型

Melinets书目系统与电子资源整合的实现技术

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现代图书情报技术 2008年第12期 99-102页

作者：应红燕北京信息科技大学图书馆

根据校园图书馆资源整合的需求,设计一个异构数据库整合系统,以提高读者对信息资源的获取效率。详细介绍该系统如何以馆藏书目系统(Melinets OPAC)为主体,将书目与异构平台上的超星、书生及时代圣典电子图书中相对应的全文信息加以链接... 详细信息

根据校园图书馆资源整合的需求,设计一个异构数据库整合系统,以提高读者对信息资源的获取效率。详细介绍该系统如何以馆藏书目系统(Melinets OPAC)为主体,将书目与异构平台上的超星、书生及时代圣典电子图书中相对应的全文信息加以链接的实现技术。

关键词：书目系统电子图书异构数据库平台资源整合

肺癌患者KDR基因酪氨酸激酶结构域的突变和多态性研究(英文)

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The Chinese-German Journal of Clinical Oncology 2009年第6期8卷 309-313页

作者： Shejuan An Zhihong Chen Jian Su Jiaying Lin ying Huang hongyan Tang Yilong Wu Medical Research Center Guangdong General Hospital Guangdong Lung Cancer Institute Guangdong Academy of Medical Sciences Guangzhou 510080 China

Objective: Although the kinase insert domain-containing receptor (KDR) gene play an very important role in the metastasis of cancer and is also as one of the molecular targets used in cancer therapy, mutation in the tyrosine kinase (TK) domain of the KDR gene has not been reported. Here we detected the mutations and polymorphisms in the TK domain of KDR gene in human lung cancer patients and to give the basic evidence and clue for cancer prevention and target therapy. Methods: The entire sequence of exons 21, 22, 23 and 27 (which contain the coding sequence of tyrosine phosphorylation) in the TK domain of KDR gene in the patients with lung cancer and control healthy individuals were assayed by PCR and DNA sequencing. We also analyzed one non-coding single nucleotide polymorphisms (SNPs) in the KDR gene. Results: No mutations were found in exon 22, 23 and 27. One heterozygous mutation of c.+2837 in exon 21 was found at a frequency of 2.08% (2/96) in the patients with lung cancer and none were detected in the healthy control individuals. The mutation was from a G to a A resulting in substitution of arginine with histidine residue. Conclusion: Our data suggested that we should focus on the mutation or SNP in the other regions or the expression levels of KDR gene, and the function of c.+2837 mutation of KDR gene may be needed further study in the future.

关键词：单核苷酸多态性酪氨酸激酶基因突变肺癌患者 KDR 受体基因中国癌症预防

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AI辅助英语学习工具的测评

外语电化教学 2024年第2期 18-24页

作者：张宏岩黄蓉李颖何建国北京大学北京市102600

近两年人工智能在大语言模型领域的突破为英语教学提供了新的可能性,而如何评价国内外涌现的AI辅助英语学习工具是使用AI工具辅助英语教学的前置需求。该研究选取了四个主要应用场景:翻译辅助、听说训练、写作纠错和智能助手,基于文献... 详细信息

近两年人工智能在大语言模型领域的突破为英语教学提供了新的可能性,而如何评价国内外涌现的AI辅助英语学习工具是使用AI工具辅助英语教学的前置需求。该研究选取了四个主要应用场景:翻译辅助、听说训练、写作纠错和智能助手,基于文献和专家意见构建了测评标准,通过分组进行对比实验,采用加权分数对20个主要AI辅助英语学习工具进行测评。

关键词： AI辅助英语学习 AI工具测评

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农村暴雨洪涝灾害防治要点探究

中国防汛抗旱 2024年第5期34卷 64-68页

作者：苗红妍孟莹辽宁省生态气象和卫星遥感中心沈阳110166 辽宁省气象局沈阳110001

在全球气候变化背景下,我国极端天气气候事件多发、频发,相比于城市地区,农村地区更易遭受自然灾害侵袭,防灾减灾任务繁重。从致灾因子危险性增大、防灾减灾基础薄弱、对灾害的认识不足和次生灾害风险高4个方面梳理了我国农村暴雨洪涝... 详细信息

在全球气候变化背景下,我国极端天气气候事件多发、频发,相比于城市地区,农村地区更易遭受自然灾害侵袭,防灾减灾任务繁重。从致灾因子危险性增大、防灾减灾基础薄弱、对灾害的认识不足和次生灾害风险高4个方面梳理了我国农村暴雨洪涝灾害现状,结合灾害防治理论,从增强领导干部的防灾减灾能力、开展韧性乡村建设、强化防灾减灾科普宣传和加强部门联动4个方面提出了农村综合防灾减灾能力建设路径,以期为加强农村地区防灾减灾能力建设提供参考。

关键词：暴雨洪涝灾害农村防灾应急管理