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Lesion region segmentation via weakly supervised learning

Quantitative Biology 2022年第3期10卷 239-252页

作者： ran yi Rui Zeng Yang Weng Minjing Yu Yu-Kun Lai Yong-Jin Liu Department of Computer Science and Technology Tsinghua UniversityBeijing 100084China College of Intelligence and Computing Tianjin UniversityTianjin 300350China School of Computer Science and Informatics Cardiff UniversityCardiffCF103ATUnited Kingdom

Background:Image-based automatic diagnosis of field diseases can help increase crop yields and is of great ***,crop lesion regions tend to be scattered and of varying sizes,this along with substantial intraclass variation and small inter-class variation makes segmentation ***:We propose a novel end-to-end system that only requires weak supervision of image-level labels for lesion region ***,a two-branch network is designed for joint disease classification and seed region *** generated seed regions are then used as input to the next segmentation stage where we design to use an encoder-decoder *** from previous works that use an encoder in the segmentation network,the encoder-decoder network is critical for our system to successfully segment images with small and scattered regions,which is the major challenge in image-based diagnosis of field *** further propose a novel weakly supervised training strategy for the encoder-decoder semantic segmentation network,making use of the extracted seed ***:Experimental results show that our system achieves better lesion region segmentation results than state of the *** addition to crop images,our method is also applicable to general scattered object *** demonstrate this by extending our framework to work on the PASCAL VOC dataset,which achieves comparable performance with the state-of-the-art DSRG(deep seeded region growing)***:Our method not only outperforms state-of-the-art semantic segmentation methods by a large margin for the lesion segmentation task,but also shows its capability to perform well on more general tasks.

关键词： weakly supervised learning lesion segmentation disease detection semantic segmentation agriculture

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Effect of Cooling Rate and Deformation on Microstructures and Critical Phase-Transformation Temperature of Boron-Nickel Added HSLA H-Beams

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Journal of Iron and Steel Research International 2012年第2期19卷 62-66页

作者： WANG Xiao WANG Zuo-cheng WANG Xie-bin WANG yi-ran GAO Jun-qing ZHAO Xiu-ling Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials Ministry of Education ShandongUniversity Jinan 250061 Shandong China Laiwu Iron and Steel Company Ltd Laiwu 271104 Shandong China）

Microstructures and critical phase-transformation temperature of boron-nickel added Nb-treated high strength low alloy （HSLA） H-beams cooled at different cooling rate, with different deformation were investigated. Continuous cooling transformation （CCT） diagram of this new type of steel was obtained by using Gleeble 1500 ther- momechanical simulator. Microstructures and hardness, especially micro-hardness of the experimental steel were in- vestigated by optical microscopy （OM）, scanning electron microscope （SEM）, Rockwell and Vickers hardness tests. Phase analysis was also studied by X^ray diffraction （XRD）. The results indicated that with increase of cooling rate, microstructures of continuous cooled specimens gradually transformed from polygonal ferrite and pearlite, grain boundary ferrite and bainite, bainite and martensite to single martensite. The CCT diagram revealed that slow cool- ing was needed to avoid austenite-bainite transformation to ensure toughness of this steel. By plastic deformation of 40%, austenite-ferrite transformation temperature increased by 46℃, due to deformation induced ferrite transfor- mation during continuous cooling, but Rockwell hardness has little change.

关键词： thermomechanical simulation HSLA H-beam microstructure CCT diagram

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Heparin is an effective treatment for preventing liver failure after hepatectomy

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World Journal of Gastroenterology 2024年第22期30卷 2881-2892页

作者： Zhi-ying Xu Min Peng Ming-Ming Fan Qi-Fei Zou yi-ran Li Dong Jiang Hepatic Surgery IV Shanghai Eastern Hepatobiliary Surgery HospitalThe Third Affiliated Hospital of Naval Medical UniversityShanghai 200433China Ultrasound Diagnosis PLA Naval Medical CenterShanghai 200437China Department of Ultrasound Eastern Hepatobiliary Surgery HospitalThe Third Affiliated Hospital of Naval Medical UniversityShanghai 200433China

BACKGROUND Posthepatectomy liver failure(PHLF)is one of the most important causes of death following liver ***,an established anticoagulant,can protect liver function through a number of mechanisms,and thus,prevent liver *** To look at the safety and efficacy of heparin in preventing hepatic dysfunction after *** The data was extracted from Multiparameter Intelligent Monitoring in Intensive Care III(MIMIC-III)v1.4 pinpointed patients who had undergone hepatectomy for liver cancer,subdividing them into two cohorts:Those who were injected with heparin and those who were *** statistical evaluations used were unpaired ttests,Mann-Whitney U tests,chi-square tests,and Fisher’s exact tests to assess the effect of heparin administration on PHLF,duration of intensive care unit(ICU)stay,need for mechanical ventilation,use of continuous renal replacement therapy(CRRT),incidence of hypoxemia,development of acute kidney injury,and ICU *** regression was utilized to analyze the factors related to PHLF,with propensity score matching(PSM)aiming to balance the preoperative disparities between the two *** In this study,1388 patients who underwent liver cancer hepatectomy were *** yielded 213 matched pairs from the heparin-treated and control *** univariate analyses indicated that heparin potentially reduces the risk of PHLF in both matched and unmatched *** analysis in the matched cohorts confirmed a significant association,with heparin reducing the risk of PHLF(odds ratio:0.518;95%confidence interval:0.295-0.910;P=0.022).Additionally,heparin treatment correlated with improved short-term postoperative outcomes such as reduced ICU stay durations,diminished requirements for respiratory support and CRRT,and lower incidences of hypoxemia and ICU *** Liver failure is an important hazard following hepatic *** ICU care heparin administration has been proved to decr

关键词： Liver resection Posthepatectomy liver failure Prophylactic treatment Heparin Prognosis of hepatectomy

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Analysis on diversified socialized relief system for solving environmental infringement

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Ecological Economy 2019年第3期12卷 217-222页

作者： DU yi-ran China University Of Petroleum Qingdao 266580CHINA

Nowadays,facing severe environmental threats and frequent pollution accidents,China is forced to pay more attention to how to relieve the damages caused by environmental infringement in a timely and effective way during the subsequent *** environmental damages nowadays are indirect,latent,and complicated,the traditional civil remedy by individuals is no longer an ideal solution to the ***,a new system is required to protect the legal rights and interests of the injured *** the title of"Analysis on Diversified Socialized Relief System to Solve Environmental Infringement",this essay adopted several research methods including document research,comparative analysis,specific normative analysis,and combination of theory and practice in order to analyze systems on environmental liability insurance,compensation fund for environmental pollution damages,special deposits in advance(sinking fund),etc..The analysis aims to help build a diversified socialized relief system which is suitable for China to solve environmental infringement.

关键词： environmental infringement compensation for damages diversification socialized relief

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Usage of a Reward System for Dealing with Pediatric Dental Fear

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Chinese Medical Journal 2016年第16期129卷 1935-1938页

作者： Yong-Hua Xia yi-ran Song Department of Children's Dental The First Hospital Affiliated to Harbin Medical University Harbin Heirongjiang 150001 China Department of Science and Technology Communication and Policy University of Science and Technology of China Hefei Anhui 230026 China

Background： Pediatric dental fear, if left unchecked, can persist for a lifetime and adversely impact the physical and psychological health of a patient. In this study, a feasible nonmedical method for relieving pediatric dental fear was investigated. Methods： A randomized, single-blind, controlled trial model was applied. The juvenile patients experiencing dental fear, whose parents or guardian had signed an informed consent form, were randomly divided into two groups. Group A （n = 50） was the control group, while Group B （n = 50） was the reward group. Participants in Group A accepted routine treatment. Participants in Group B were told that they would obtain a gift as a reward for their good behavior if they were compliant during their dental treatments. The Chinese version of the Children＇s Fear Survey Schedule-Dental Subscale （CFSS-DS） was used to evaluate the level of dental fear of each patient both before and after each treatment. A contrast analysis and a correlation analysis of the results were used to assess the efficacy of the reward mechanism. Results： All participants in Group B, were obedient during the dental treatment, and they also successfully chose the present they wanted at the end of their dental treatment. Children at different ages showed different reward preferences. Significant difference in the fear scores of the participants in Group B before the treatment and after receiving the reward was found （independent samples t-test, t = 14.72, P 〈 0.001）. In Group A, 86% children＇s fear score did not undergo a noticeable change. Conclusions： A reward system is proved feasible to relieve pediatric dental fear, and the form of reward should meet the demand of patients.

关键词： Nonmedical Way Pediatric Dental Fear Reward Mechanism

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Predicting hepatocellular carcinoma: A new non-invasive model based on shear wave elastography

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World Journal of Gastroenterology 2024年第25期30卷 3166-3178页

作者： Dong Jiang yi Qian yi-Jun Gu Ru Wang Hua Yu Hui Dong Dong-Yu Chen Yan Chen Hao-Zheng Jiang Bi-Bo Tan Min Peng yi-ran Li Department of Ultrasound Eastern Hepatobiliary Surgery HospitalThe Third Affiliated Hospital of Naval Medical UniversityShanghai 200433China Department of Pathology Shanghai Eastern Hepatobiliary Surgery HospitalThird Affiliated Hospital of Naval Medical UniversityShanghai 200433China Department of College of Art and Science Case Western Reserve UniversityClevelandOH 44106United States Ultrasound Diagnosis PLA Naval Medical CenterShanghai 200437China

BACKGROUND Integrating conventional ultrasound features with 2D shear wave elastography(2D-SWE)can potentially enhance preoperative hepatocellular carcinoma(HCC)*** To develop a 2D-SWE-based predictive model for preoperative identification of *** A retrospective analysis of 884 patients who underwent liver resection and pathology evaluation from February 2021 to August 2023 was conducted at the Oriental Hepatobiliary Surgery *** patients were divided into the modeling group(n=720)and the control group(n=164).The study included conventional ultrasound,2D-SWE,and preoperative laboratory *** logistic regression was used to identify independent predictive factors for RESULTS In the modeling group analysis,maximal elasticity(Emax)of tumors and their peripheries,platelet count,cirrhosis,and blood flow were independent risk indicators for *** factors yielded an area under the curve of 0.77(95%confidence interval:0.73-0.81)with 84%sensitivity and 61%*** model demonstrated good calibration in both the construction and validation cohorts,as shown by the calibration graph and Hosmer-Lemeshow test(P=0.683 and P=0.658,respectively).Additionally,the mean elasticity(Emean)of the tumor periphery was identified as a risk factor for microvascular invasion(MVI)in malignant liver tumors(P=0.003).Patients receiving antiviral treatment differed significantly in platelet count(P=0.002),Emax of tumors(P=0.033),Emean of tumors(P=0.042),Emax at tumor periphery(P<0.001),and Emean at tumor periphery(P=0.003).CONCLUSION 2D-SWE’s hardness value serves as a valuable marker for enhancing the preoperative diagnosis of malignant liver lesions,correlating significantly with MVI and antiviral treatment efficacy.

关键词： Shear wave elastography Predicting model Microvascular invasion Antiviral treatment Hepatocellular carcinoma

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Single-atom catalysts:controlled synthesis and dynamic mechanism in electrochemical oxygen evolution substitution reactions

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Rare Metals 2024年第10期43卷 4903-4920页

作者： Qin Zhao Rong Gan yi-Ling ran Quan-Lei Ma Wen-Wen Chen Yue-Xin Guo Yan Zhang Ding-Sheng Wang School of Chemistry Southwest Jiaotong UniversityChengdu 610031China School of Life Science and Engineering Southwest Jiaotong UniversityChengdu 610031China Engineering Research Center of Advanced Rare Earth Materials Department of ChemistryTsinghua UniversityBeijing 100084China

Single-atom catalysts(SACs)have attracted much attention in the field of electrocatalysis due to their100%atomic utilization efficiency,clear active center and adjustable *** application of SACs to anodic oxygen evolution substitution reactions with high conversion efficiency and selectivity is undoubtedly ***,a full understanding of the interactions between metal single-atom active sites and supports,and an in-depth understanding of the active centers and catalytic mechanisms of SACs in the electro-oxidation of small molecules are the keys to the development of high-performance *** review focuses on the synthesis of different support SACs and the interactions between single atoms and supports at the inter-face,and introduces the reaction mechanism of SACs in the electro-oxidation of different small-molecule substrates,such as ethanol,urea and hydrazine,with the aim of providing insights and ideas for the design of more efficient and ideal ***,we discuss the current challenges and future opportunities in the field.

关键词： Single-atom catalysts Supports Synthesis Oxygen evolution substitution reaction Electrochemical oxidation mechanism

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Economic burden of premature deaths attributable to different heatwaves in China: A multi-site study, 2014-2019

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Advances in Climate Change Research 2023年第6期14卷 836-846页

作者： Cheng ZHAO Yong-Hong LI Shilu TONG Rong WANG Yu WANG yi-Bin CHENG yi-ran LYU Yu-Shu HUANG Jiang HE Jia GUO Xiao-Yuan YAO China CDC Key Laboratory of Environment and Population Health National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijing 100021China School of Public Health Institute of Environment and Population HealthAnhui Medical UniversityHefei 230032China School of Public Health and Social Work Queensland University of TechnologyBrisbane 4006Australia National Climate Center China Meteorological AdministrationBeijing 100081China

It has been well documented that heatwaves are linked to elevated mortality and ***,the selection of optimal heatwave definitions for subsequent risk assessment has been inconsistent and there is no full picture of the effects of heatwaves with different intensities on economic losses due to mortality,which can provide important insights for public health ***,we used a two-stage time series analysis,combined with values of statistical life(VsL)based on the value of a statistical life year to assess the economic burden of deaths associated with heatwaves of different intensities and durations and to identify the vulnerable populations and *** further conducted stratified analyses by age,sex,and *** found 2.9%(95%CI:0.0%,6.5%)-20.0%(95%CI:2.9%,34.2%)of VsL were attributable to heatwaves,corresponding to attributable economic losses(AELs)of 2.20(95%CI:0.32,3.77)-4.77(95%CI:1.53,7.63)billion *** economic burden of death was most sensitive to heatwave H99P_2D(99th percentile,at last 2 consecutive days),while H97.5P_2D(97.5th percentile,at last 2 consecutive days)caused the highest attributable economic *** and elderly people aged≥65 years were more *** AELs in the temperate zone and northern regions were larger than those in subtropical zone and southern regions during relatively low-intensity heatwaves,*** contrast,the AELs in subtropical zone and southern regions were relatively higher than those in temperate zone and northern regions during relatively high-intensity heatwaves,*** AELs were larger in urban areas than in rural *** intervention strategies,primarily focusing on vulnerable populations and regions,should be formulated to reduce the economic loss due to heatwaves in the context of climate change.

关键词： Heatwaves Economic burden Mortality Values of statistical life

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Sexual and reproductive health service needs of university/ college students： updates from a survey in Shanghai, China

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Asian Journal of Andrology 2008年第4期10卷 607-615页

作者： Bin Chen Yong-Ning Lu Hong-Xiang Wang Qing-Liang Ma Xiao-Ming Zhao Jian-Hua Guo Kai Hu yi-Xin Wang yi-ran Huang Pei Chen Department of Urology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200001 China Department of Obestetric ＆ Gynecology Renii Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200001 China Shanghai Institute of Andrology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200001 China Center for Reproductive Medicine Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200001 China

Aim： To promote the provision of reproductive health services to young people by exploring the attitudes and perceptions of university students in Shanghai, China, toward reproductive health. Methods： From July 2004 to May 2006, 5 243 students from 14 universities in Shanghai took part in our survey. Topics covered the demands of reproductive health-care services, attitudes towards and experience with sex, exposure to pornographic material, and knowledge on sexual health and sexually transmitted infections （STIs）/AIDS. Results： Of the 5 067 students who provided valid answer sheets, 50.05% were female and 49.95% were male, 14.86% were medical students, and 85.14% had non-medical backgrounds. A total of 38.4% of respondents had received reproductive health education previously. The majority of students supported school-based reproductive health education, and also acquired information about sex predominantly from books, schoolmates, and the Internet. Premarital sexual behavior was opposed by 17.7% of survey participants, and 37.5% could identify all the three types of STIs listed in the questionnaire. Although 83.7% knew how HIV is transmitted, only 55.7% knew when to use a condom and 57.8% knew that the use of condoms could reduce the risk of HIV infection. Conclusion： The reproductive health service is lagging behind current attitudes and demands of university students. Although students＇ attitudes towards sexual matters are liberal, their knowledge about reproductive health and STIs/AIDS is still limited. It is therefore necessary to provide effective and confidential reproductive health services to young people.

关键词： reproductive health reproductive health services safe sex sexual behavior sexuality

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RADepthNet:Reflectance-aware monocular depth estimation

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Virtual Reality & Intelligent Hardware 2022年第5期4卷 418-431页

作者： Chuxuan LI ran yi Saba Ghazanfar ALI Lizhuang MA Enhua WU Jihong WANG Lijuan MAO Bin SHENG Department of Computer Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China Department of State Key Laboratory of Computer Science University of MacaoMacao 999078China Shanghai University of Sports Shanghai 200438China

Background Monocular depth estimation aims to predict a dense depth map from a single RGB image,and has important applications in 3D reconstruction,automatic driving,and augmented ***,existing methods directly feed the original RGB image into the model to extract depth features without avoiding the interference of depth-irrelevant information on depth-estimation accuracy,which leads to inferior *** To remove the influence of depth-irrelevant information and improve the depth-prediction accuracy,we propose RADepthNet,a novel reflectance-guided network that fuses boundary ***,our method predicts depth maps using the following three steps:(1)Intrinsic Image *** propose a reflectance extraction module consisting of an encoder-decoder structure to extract the depth-related *** an ablation study,we demonstrate that the module can reduce the influence of illumination on depth estimation.(2)Boundary Detection.A boundary extraction module,consisting of an encoder,refinement block,and upsample block,was proposed to better predict the depth at object boundaries utilizing gradient constraints.(3)Depth Prediction *** use an encoder different from(2)to obtain depth features from the reflectance map and fuse boundary features to predict *** addition,we proposed FIFADataset,a depth-estimation dataset applied in soccer *** Extensive experiments on a public dataset and our proposed FIFADataset show that our method achieves state-of-the-art performance.

关键词： Monocular depth estimation Deep learning Intrinsic image decomposition

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