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Role of phosphorus on the biogeochemical behavior of cadmium in the contaminated soil under leaching and pot experiments

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Journal of Environmental Sciences 2024年第3期137卷 488-499页

作者： Hui jia YifanWu Mengqi Zhang Jinhui ye Daolin Du He Wang Institute of Environment and Ecology School of Emergency ManagementJiangsu UniversityZhenjiang 212013China School of the Environment and Safety Engineering&Institute of Environment and Ecology Jiangsu UniversityZhenjiang 212013China jiangsu Collaborative Innovation Center of Technology and Material of Water Treatment Suzhou University of Science and TechnologySuzhou 215009China Xuzhou Medical University Affiliated HospitalXuzhou 221004China

Phosphorus(P)is involved in various biochemical reactions in plant growth,so it is beneficial to plants growing in soils contaminated by metals,including cadmium(Cd).However,few studies have reported on the mechanistic roles of P in mitigating Cd toxicity to ryegrass root,and especially in alleviating the disruption of the mitochondrial function of living *** this study,the physiological and biochemical mechanisms associated with ryegrass growth under various Cd and P treatments were investigated using leaching and pot *** concentration of Cd in soil leachates showed a significantly positive relationship with redox potential(P<0.05),but negative relationship(P<0.05)with leachate pH values and dissolved organic carbon(DOC),indicating that exogenous P addition(as H_(2)PO_(4)*)may decrease Cd leaching from contaminated *** to the control(without P addition),the cumulative Cd content was reduced by 53.3%and 64.5%in the soil leachate with exogenous P application(20 mg/L and 80 mg/L),***,application of P decreased the Cd concentrations in the symplastic fractions and increased the Cd concentrations in the apoplastic fractions in root tips,which may help to alleviate Cd stress to the ***,exogenous P was found to play a positive role in mitochondrial function and Ca^(2+)variation in root cells under Cd stress,which provides novel insights into the mechanisms of exogenous P in alleviating plant Cd injury.

关键词： Phosphorus Cadmium stress Protoplast Biogeochemical behavior Mitochondrial function

Flow characterization of macroporous W-4.8 vol.%ZrO2 alloy during hot deformation with improved constitutive equation and processing maps

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Tungsten 2024年第3期6卷 610-620页

作者： jia-Hao ye Liu-Jie Xu Ji-Kang Hu School of Materials Science and Engineering Henan University of Science and Technology National Joint Engineering Research Center for Abrasion Control and Molding of Metal Materials Henan University of Science and Technology

In this work,isothermal compression experiments of macroporous W-4.8 vol.%ZrO2（W-4.8ZrO2） at 1300-1600℃ and strain rate of 0.005-1 s-1were carried out on a Gleeble-1500D thermo-mechanical *** dynamic recovery of W-4.8ZrO2is the main "softening" *** the basis of Arrhenius model,the initial constitutive equation is established by exploring the influence of temperature,strain rate and rheological *** on Arrhenius model,the relationship between flow stress,strain rate and deformation temperature is *** the influence of strain,the improved constitutive equation and the law of material constant changing with the strain are *** that,the hot processing maps were drawn on the basis of the dynamic material model,which is used to analyze the instability mechanism of the W-4.8ZrO2,and determine the appropriate hot working process parameters(temperature:1350-1450℃,strain rate:0.1-1 s-1).

关键词： Tungsten alloy Flow characteristics Constitutive equation Hot processing maps

Curcumin Interferes with TGF-β1-Induced Fibrosis in NRK-49F Cells by Reversing ADAMTS18 Gene Methylation

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Chinese Journal of Integrative Medicine 2024年第7期30卷 600-607页

作者： XU Ben ZHANG jia-en ye Lin YUAN Chang-wei Department of Urology Peking University First Hospital and Institute of UrologyPeking UniversityNational Urological Cancer CenterBeijing100034China

Objective To explore the molecular mechanism by which curcumin affects renal interstitial fibrosis(RIF)progression by regulating ADAM metallopeptidase with thrombospondin type 1 motif 18(ADAMTS18)*** NRK-49F cells RIF model were induced with transforming growth factorβ1(TGF-β1).Effects of different concentrations of curcumin(0,10,20,and 30μmol/L)on cell proliferation,cell cycle,cell apoptosis as well as cyclin D1 expression were analyzed by cell counting kit-8,flow cytometry and Western blot,***18 methylation levels were determined by methylation-specific polymerase chain ***18,fibronectin(FN),type I collagen(Col-I)and alpha-smooth muscle actin(α-SMA)mRNA and protein expressions were analyzed by real-time PCR(RT-PCR)and Western blot,***,cells were treated with 50 mmol/L 5-aza-2′-deoxycytidine(5-aza-dC,demethylation agent)for 72 *** of curcumin on extracellular matrix(ECM)deposition was evaluated by immunochemical staining and Western ***-49F cells were transfected with ADAMTS18 small interfering RNA and grouped into a normal control,ADAMTS18-knock-out(KO),and ADAMTS18-KO+30μmol/L curcumin groups,and whether curcumin can reverse the effect of ADAMTS18 knockdown on RIF was *** Compared with the control group,TGF-β1 significantly inhibited the proliferation of NRK-49F cells,blocked the G1/G0 phase,promoted cell apoptosis and inhibited cyclin D1 expression(P<0.01).Among the different concentrations of curcumin,30μmol/L curcumin significantly reversed these processes(P<0.01).Immunochemical staining and Western blot results showed that curcumin significantly inhibited the deposition of FN,Col-I andα-SMA(P<0.01).Curcumin and 5-zaz-dC had synergistic effects,promoting ADAMTS18 expression,removing ADAMTS18 methylation,and reducing ECM ***18 knockdown promoted ECM accumulation,and curcumin reversed this process(P<0.01).Conclusion TGF-β1-induced fibrosis in NRK-49F ***

关键词： renal fibrosis curcumin Chinese medicine ADAMTS18 methylation modification

Roles of fibroblast growth factors in the treatment of diabetes

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World Journal of Diabetes 2024年第3期15卷 392-402页

作者： Chun-ye Zhang ming Yang Bond Life Sciences Center University of MissouriColumbiaMO 65211United States Department of Surgery University of MissouriColumbiaMO 65212United States NextGen Precision Health Institution University of MissouriColumbiaMO 65212United States

Diabetes affects about 422 million people worldwide,causing 1.5 million deaths each ***,the incidence of diabetes is increasing,including several types of *** 1 diabetes(5%-10%of diabetic cases)and type 2 diabetes(90%-95%of diabetic cases)are the main types of diabetes in the *** evidence shows that the fibroblast growth factor(FGF)family plays important roles in many metabolic disorders,including type 1 and type 2 *** consists of 23 family members(FGF-1-23)in ***,we review current findings of FGFs in the treatment of diabetes and management of diabetic *** FGFs(e.g.,FGF-15,FGF-19,and FGF-21)have been broadly investigated in preclinical studies for the diagnosis and treatment of diabetes,and their therapeutic roles in diabetes are currently under investigation in clinical ***,the roles of FGFs in diabetes and diabetic complications are involved in numerous ***,FGF intervention can prevent high-fat diet-induced obesity and insulin resistance and reduce the levels of fasting blood glucose and triglycerides by regulating lipolysis in adipose tissues and hepatic glucose ***,modulation of FGF expression can inhibit renal and cardiac fibrosis by regulating the expression of extracellular matrix components,promote diabetic wound healing process and bone repair,and inhibit cancer cell proliferation and ***,FGFs can regulate the activation of glucoseexcited neurons and the expression of thermogenic genes.

关键词： Fibroblast growth factors Type 1 diabetes Type 2 diabetes Metabolic disorders Treatment Clinical trials

Digital signal acquisition system for complex nuclear reaction experiments

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Nuclear Science and Techniques 2024年第1期35卷 124-133页

作者： Wei-Liang Pu Yan-Lin ye jian-Ling Lou jia-Hao Chen School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijing 100871China Institute of Applied Physics and Computational Mathematics Beijing 100094China

A digital data-acquisition system based on XIA LLC products was used in a complex nuclear reaction experiment using radioactive ion beams.A flexible trigger system based on a field-programmable gate array(FPGA)parametrization was developed to adapt to different experimental sizes.A user-friendly interface was implemented,which allows converting script language expressions into FPGA internal control *** proposed digital system can be combined with a conventional analog data acquisition system to provide more *** performance of the combined system was veri-fied using experimental data.

关键词： Digital signal acquisition system Trigger Programmable logic Timestamp

Verification of quantum networks using the GHZ paradox

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Communications in Theoretical Physics 2024年第10期76卷 57-63页

作者： Huan ye Xue Yang ming-Xing Luo School of Information Science and Technology Southwest Jiaotong University School of Computer Science and Cyber Security Chengdu University of Technology

The Greenberger–Horne–Zeilinger(GHZ) paradox shows that it is possible to create a multipartite state involving three or more particles in which the measurement outcomes of the particles are correlated in a way that cannot be explained by classical physics. We extend it to witness quantum networks. We first extend the GHZ paradox to simultaneously verify the GHZ state and Einstein–Podolsky–Rosen states on triangle networks. We then extend the GHZ paradox to witness the entanglement of chain networks consisting of multiple GHZ states. All the present results are robust against the noise.

关键词： GHZ paradox quantum entanglement quantum network

Enhanced preparation of dendritic metallic vanadium in recyclable NaCl-KCl-VCl_(2) molten salt by V_(2)CO electrolysis

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Rare Metals 2024年第8期43卷 3961-3973页

作者： jia-Liang An ming-Yong Wang Yong-Zheng jia Jin-Tao Zhang Bao-Yan Feng Shu-Qiang jiao State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China College of Material Science and Engineering Hebei Province Laboratory of Inorganic Nonmetallic MaterialsNorth China University of Science and TechnologyTangshan 063210China

A promising method for the preparation of pure metallic vanadium via V_(2)CO anode electrolysis was proposed and *** simple and controllable synthesis of a molten chloride salt containing VCl_(2) by an insitu reaction between VCl_(3) and metallic vanadium was verified through thermodynamic analysis and ***-KCl-VCl_(2) molten salt exhibited excellent recycling performance and could be repetitively used to prepare metallic vanadium by V_(2)CO *** V^(2+) ions remained in the molten salt after *** electrolysis conditions,such as the cathode diameter,current density,V^(2+) ion concentration,and temperature,were optimised to maximise the current *** was also simulated to reveal the regulatory *** highest current efficiency was 85%.The purity of metallic vanadium was up to 99.8%.In this study,an easy and efficient preparation of pure metallic vanadium was achieved.

关键词： V_(2)CO Metallic vanadium Current efficiency Molten salt electrolysis

Pindel-TD:A Tandem Duplication Detector Based on A Pattern Growth Approach

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Genomics, Proteomics & Bioinformatics 2024年第1期22卷 99-104页

作者： Xiaofei Yang Gaoyang Zheng Peng jia Songbo Wang Kai ye School of Computer Science and Technology Faculty of Electronic and Information EngineeringXi’an Jiaotong UniversityXi’an 710049China Center for Mathematical Medical the First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061China Genome Institute the First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061China MOE Key Lab for Intelligent Networks&Networks Security Faculty of Electronic and Information EngineeringXi’an Jiaotong UniversityXi’an 710049China School of Automation Science and Engineering Faculty of Electronic and Information EngineeringXi’an Jiaotong UniversityXi’an 710049China School of Life Science and Technology Xi’an Jiaotong UniversityXi’an 710049China Faculty of Science Leiden UniversityLeiden 2311 EZNetherland

Tandem duplication(TD)is a major type of structural variations(SVs)that plays an important role in novel gene formation and human ***,TDs are often missed or incorrectly classified as insertions by most modern SV detection methods due to the lack of specialized operation on TD-related mutational ***,we developed a TD detection module for the Pindel tool,referred to as Pindel-TD,based on a TD-specific pattern growth ***-TD is capable of detecting TDs with a wide size range at single nucleotide *** simulated and real read data from HG002,we demonstrated that Pindel-TD outperforms other leading methods in terms of precision,recall,F1-score,and ***,by applying Pindel-TD to data generated from the K562 cancer cell line,we identified a TD located at the seventh exon of SAGE1,providing an explanation for its high ***-TD is available for non-commercial use at https://***/xjtu-omics/pindel.

关键词： Tandem duplication Pattern growth Short-read sequencing Structural variation SAGE1

Sedimentary paleoenvironment and its control on organic matter enrichment in the Mesoproterozoic hydrocarbon source rocks in the Ordos Basin, southern margin of the North China Craton

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Petroleum Science 2024年第4期21卷 2257-2272页

作者： Zhi-Chen Wu Ju-ye Shi Tai-Liang Fan ming jiang School of Energy Resources China University of Geosciences (Beijing) Key Laboratory of Marine Reservoir Evolution and Hydrocarbon Enrichment Mechanism Ministry of Education China University of Geosciences (Beijing)

The black shale of the Mesoproterozoic Cuizhuang Formation in the Changcheng System in Yongji city,North China Craton, is a potential source rock. Understanding the organic matter enrichment mechanism is crucial for evaluating source rock resources and understanding oil and gas accumulation *** this study, we evaluated the sedimentary paleoenvironment and organic matter enrichment mechanisms of shale using thin section observations, mineral composition analysis, organic geochemistry, and elemental geochemistry. We found significant differences in the sedimentary paleoenvironment and organic matter enrichment mechanisms between the lower Cuizhuang Formation and the Beidajian Formation shale. The Cuizhuang Formation was deposited in a late-stage, restricted basin environment during the rift phase, and elemental and geochemical indicators showed that the Cuizhuang Formation was in a suboxic-anoxic water environment, that was influenced by a warm and humid paleoclimate and submarine hydrothermal activities, which promoted the accumulation of organic matter. However, the enrichment of organic matter in the Cuizhuang Formation was mainly controlled by redox *** formation of suboxic-anoxic water environments may be closely related to the warm and humid paleoclimate and submarine hydrothermal activities. Warm conditions promote continental weathering and increase marine productivity, thereby consuming oxygen in the bottom water. Moreover, acidic hydrothermal activity also helps to establish an anoxic environment. Our results reveal the effects controlling various coupled mechanisms dominated by redox conditions, which may explain the development of source rocks in the Cuizhuang Formation.

关键词： Cuizhuang formation Paleoproterozoic source rocks Marine productivity Paleoenvironments Submarine hydrothermal activity Organic matter enrichment