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Transurethral seminal vesiculoscopy in the diagnosis and treatment of persistent or recurrent hemospermia： a single- institution experience

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Asian Journal of Andrology 2009年第5期11卷 566-570,I0002页

作者： Zhi-Yong Liu Ying-Hao Sun Chuan-Liang Xu Jian-Guo Hou Xu Gao Xin Lu Hua-Mao ye lin-hui Wang Xiao-Feng Gao Shanghai Changhai Hospital the Second Military Medical University Shanghai 200433 China

The diagnosis and treatment of hemospermia presents significant difficulty, especially if it persists or recurs. In this retrospective study, we assessed whether transurethral seminal vesiculoscopy is feasible and effective in the diagnosis and treatment of hemospermia. To address this complex condition, we report our experience in a population of patients treated with transurethral seminal vesiculoscopy. From February 2006 to July 2008, 72 hemospermic patients underwent transurethral seminal vesiculoscopy examination and treatment at our urology center. Transurethral seminal vesiculoscopy was performed by a 7-F or 8-F rigid ureteroscope. The endoscopic procedure was conducted through the normal anatomic route of the seminal tracts. In this series, the mean follow-up period was 21.7 months. Definite diagnosis was made for 93.1% patients, and 94.4% patients were cured or showed a decrease in their symptoms. Postoperative complications were not observed in the study. Our study proves that transurethral seminal vesiculoscopy is effective in the diagnosis and treatment of hemospermia with minimal complication.

关键词： diagnosis hemospermia transurethral seminal vesiculoscopy treatment

From Physical Space to Visual Image Space

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Geo-Spatial Information Science 2003年第2期6卷 42-47页

作者： ye Zetian lin hui LIU Xianlin ye Zetian, Ph.D, Chinese Academy of Surveying and Mapping, 16 Beitaiping Road, Haidian District, Beijing 100039, China. Chinese Academy of Surveying and Mapping

The theoretical framework of visual simulation in virtual reality is discussed. The new concept of visual image space is supposed. On the basis of visual image space, in visual perceptive sense, VR is considered as a spatial simulation. The objective of the spatial simulation is to transform physical space to visual image space. Last, the prototype system, surveying & mapping virtual Reality (SMVR), is developed, and the space simulation above is realized. By use of SMVR, the real 3D representation, 3D visual analysis, virtual plan and designs can be implemented.

关键词： virtual reality physical space visual image space space of earth surface space simulation

Effect of cholesterol metabolism on hepatolithiasis

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World Journal of Gastroenterology 2025年第1期31卷 157-162页

作者： lin Zheng Zi-Yu ye Jun-Ji Ma Department of Gastroenterology The Second Hospital of Hebei Medical UniversityHebei Key Laboratory of GastroenterologyHebei Institute of GastroenterologyHebei Clinical Research Center for Digestive DiseasesNo.215 Heping West RoadShijiazhuang 050000Hebei ProvinceChina

Surgical intervention is currently the primary treatment for hepatolithiasis;how-ever,some patients still experience residual stones and high recurrence rates after *** metabolism seems to play an important role in hepatoli-thiasis pathogenesis.A high cholesterol diet is one of the significant reasons for the increasing incidence of ***,regular diet and appropriate medical intervention are crucial measures to prevent hepatolithiasis and reduce recurrence rate after *** dietary cholesterol and drugs that increase cholesterol stone solubility are key therapeutic approaches in treating *** article discusses the cholesterol metabolic pathways related to the pathogenesis of hepatolithiasis,as well as food intake and targeted therapeutic drugs.

关键词： Hepatolithiasis Cholesterol metabolism High-fat diet 3-hydroxy-3-methylglutaryl-coenzyme A reductase Interlobular bile duct

Prussian Blue Analogue‑Templated Nanocomposites for Alkali‑Ion Batteries:Progress and Perspective

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Nano-Micro Letters 2025年第1期17卷 216-261页

作者： Jian‑En Zhou Yilin Li Xiaoming lin Jiaye ye Key Laboratory of Theoretical Chemistry of Environment Ministry of EducationSchool of ChemistrySouth China Normal UniversityGuangzhou 510006People’s Republic of China School of Chemistry and Physics Faculty of ScienceQueensland University of Technology2 George StreetBrisbaneQLD 4000Australia Centre for Materials Science Queensland University of Technology2 George StreetBrisbaneQLD 4000Australia

Lithium-ion batteries(LIBs)have dominated the portable electronic and electrochemical energy markets since their commercialisation,whose high cost and lithium scarcity have prompted the development of other alkali-ion batteries(AIBs)including sodium-ion batteries(SIBs)and potassium-ion batteries(PIBs).Owing to larger ion sizes of Na^(+)and K^(+)compared with Li^(+),nanocomposites with excellent crystallinity orientation and well-developed porosity show unprecedented potential for advanced lithium/sodium/potassium *** enticing open rigid framework structures,Prussian blue analogues(PBAs)remain promising self-sacrificial templates for the preparation of various nanocomposites,whose appeal originates from the well-retained porous structures and exceptional electrochemical activities after thermal *** review focuses on the recent progress of PBA-derived nanocomposites from their fabrication,lithium/sodium/potassium storage mechanism,and applications in AIBs(LIBs,SIBs,and PIBs).To distinguish various PBA derivatives,the working mechanism and applications of PBA-templated metal oxides,metal chalcogenides,metal phosphides,and other nanocomposites are systematically evaluated,facilitating the establishment of a structure–activity correlation for these *** on the fruitful achievements of PBA-derived nanocomposites,perspectives for their future development are envisioned,aiming to narrow down the gap between laboratory study and industrial reality.

关键词： Prussian blue analogues Self-sacrificial template Lithium-ion batteries Sodium-ion batteries Potassium-ion batteries

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江西林业系统自然保护区管理建设及建议

中国林业经济 2019年第1期 129-130页

作者：叶惠林安远县高云山林场江西赣州342101

从江西自然地理特征和林业系统自然保护区现状进行分析,结合文献资料对江西林业系统自然保护区多角度管理模式进行评述,以经济效益、生态效益和社会效益这三个重点方向进行评述总结,对未来保护与发展提出了合理化建议和展望。

关键词：自然保护区管理模式江西省

Real-world evidence on the efficacy and safety of vonoprazanamoxicillin dual therapy for Helicobacter pylori treatment in elderly patients

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World Journal of Gastroenterology 2025年第1期31卷 68-78页

作者： Wen Gao Jing-Wen Li hui ye Xue-Zhi Zhang Jian-Xiang Liu Hong Cheng Department of Gastroenterology Peking University First HospitalBeijing 100034China School of Medicine Tsinghua MedicineTsinghua UniversityBeijing 100034China Department of Traditional Chinese Medicine and Integrative Medicine Peking University First HospitalBeijing 100034China

BACKGROUND A dual therapy regimen containing amoxicillin is a common treatment option for the eradication of Helicobacter pylori(***).While substantial research supports the efficacy and safety of vonoprazan and amoxicillin(VA)dual therapy in the general population,there is still a lack of studies specifically focusing on its safety in elderly *** To evaluate efficacy and safety of VA dual therapy as first-line or rescue treatment for *** in elderly *** As a real-world retrospective study,data were collected from elderly patients aged 60 years and above who accepted VA dual therapy(vonoprazan 20 mg twice daily+amoxicillin 1000 mg thrice daily for 14 days)for *** eradication in the Department of Gastroenterology at Peking University First Hospital between June 2020 and January *** status was evaluated by^(13)C-urease breath test 6 weeks after *** adverse events(AEs)during treatment were *** In total,401 cases were ***-one cases were excluded due to loss to follow-up,lack of re-examination,or unwillingness to take *** total of 380 included cases comprised 250 who received VA dual therapy as first-line treatment and 130 who received VA dual therapy as rescue *** was successfully eradicated in 239 cases(95.6%)in the first-line treatment group and 116 cases(89.2%)in the rescue treatment *** overall incidence of AEs was 9.5%for both ***,9.2%of patients experienced an AE in the first-line treatment group and 10.0%in the rescue treatment *** patients discontinued treatment due to AE,with a discontinuation rate of 1.3%.No serious AE *** The VA dual therapy regimen as a first-line treatment and a rescue therapy was effective and safe for elderly patients aged 60 and older.

关键词： Helicobacter pylori Vonoprazan Amoxicillin Dual therapy Elderly

Targeted gene sequencing and bioinformatics analysis of patients with gallbladder neuroendocrine carcinoma:A case report

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 239-251页

作者： Yun-Chuan Yang Zhi-Tao Chen Da-Long Wan hui Tang Mu-lin Liu Department of Medical College Jinan UniversityGuangzhou 510000Guangdong ProvinceChina Department of General Surgery The First Affiliated Hospital of Bengbu Medical UniversityBengbu 233000Anhui ProvinceChina Department of Hepatobiliary Surgery Shulan(Hangzhou)Hospital Affiliated to Zhejiang Shuren University Shulan International Medical CollegeHangzhou 310022Zhejiang ProvinceChina Department of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310003Zhejiang ProvinceChina Department of Pathology The First Affiliated Hospital of Medical School of Zhejiang UniversityHangzhou 310000Zhejiang ProvinceChina

BACKGROUND Gallbladder neuroendocrine carcinoma(NEC)represents a subtype of gallbladder malignancies characterized by a low incidence,aggressive nature,and poor *** its clinical severity,the genetic alterations,mechanisms,and signaling pathways underlying gallbladder NEC remain *** SUMMARY This case study presents a rare instance of primary gallbladder NEC in a 73-year-old female patient,who underwent a radical cholecystectomy with hepatic hilar lymphadenectomy and resection of liver segments IV-B and *** gene sequencing and bioinformatics analysis tools,including STRING,GeneMANIA,Metascape,TRRUST,Sangerbox,cBioPortal and GSCA,were used to analyze the biological functions and features of mutated genes in gallbladder *** mutations(APC,ARID2,IFNA6,KEAP1,RB1,SMAD4,TP53,BTK,GATA1,GNAS,and PRDM3)were identified,and the tumor mutation burden was determined to be 9.52 muts/Mb via targeted gene sequencing.A protein-protein interaction network showed significant interactions among the twelve mutated *** Ontology and Kyoto Encyclopedia of Genes and Genomes analyses were used to assess mutation functions and *** results revealed 40 tumor-related pathways.A key regulatory factor for gallbladder NEC-related genes was identified,and its biological functions and features were compared with those of gallbladder *** Gallbladder NEC requires standardized *** with other gallbladder carcinomas revealed clinical phenotypes,molecular alterations,functional characteristics,and enriched pathways.

关键词： Gallbladder neuroendocrine carcinoma Targeted-gene sequencing Bioinformatics analysis case report Immunocytochemistry Case report

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471例儿童α地中海贫血缺失型基因谱分析

中国当代儿科杂志 2012年第4期14卷 264-266页

作者：林业辉范联张章潘志伟宋春林南方医科大学附属佛山市妇幼保健院儿科广东佛山528000 南方医科大学附属佛山市妇幼保健院中心实验室广东佛山528000

目的探讨儿童α地中海贫血(α地贫)常见缺失型基因谱的分布特征。方法在佛山市妇幼保健院就诊和体检的儿童中,血细胞分析检测红细胞体积(MCV)<82 fl者抽取静脉血2 mL(EDTA抗凝),采用GAP-PCR法进行α地贫基因分析。结果血细胞分析MCV<82... 详细信息

目的探讨儿童α地中海贫血(α地贫)常见缺失型基因谱的分布特征。方法在佛山市妇幼保健院就诊和体检的儿童中,血细胞分析检测红细胞体积(MCV)<82 fl者抽取静脉血2 mL(EDTA抗凝),采用GAP-PCR法进行α地贫基因分析。结果血细胞分析MCV<82 fl者1341例,检出α地贫471人,检出率为35.1%,且随年龄增长而增高。基因缺失以东南亚缺失型(--SEA)为主,占75.3%;其次为右侧缺失型(-а3.7),占17.0%;左侧缺失型(-а4.2)占7.7%。基因型分布前3位分别是:--SEA/аа(73.2%),аа/-а3.7(12.5%)和--SEA/-а3.7(5.5%)。结论对MCV<82 fl儿童进行α地贫的基因诊断是必要的。该资料中α地贫患儿基因缺失以东南亚缺失型(--SEA)占主导地位,基因型以--SEA/aa多见。

关键词：地中海贫血基因分析儿童

基于蝴蝶突变离子型稀土冶炼分离过程危险性分析

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有色金属科学与工程 2013年第4期4卷 107-110页

作者：林大建叶慧琳江西理工大学资源与环境工程学院江西赣州341000

离子型稀土冶炼分离生产工艺流程包含:酸溶、萃取、沉淀、灼烧等,研究分析稀土冶炼分离过程中使用的危险物质的特点,指出生产工艺中存在中毒、灼烧、机械伤害等危险性以及萃取厂房的耐火等级偏低,防火分区不符合安全要求等问题.分析生... 详细信息

离子型稀土冶炼分离生产工艺流程包含:酸溶、萃取、沉淀、灼烧等,研究分析稀土冶炼分离过程中使用的危险物质的特点,指出生产工艺中存在中毒、灼烧、机械伤害等危险性以及萃取厂房的耐火等级偏低,防火分区不符合安全要求等问题.分析生产过程中存在的危险有害因素,利用蝴蝶型突变理论,建立离子型稀土冶炼分离企业的安全生产保障体系、危险程度界定和突变级数分级模型,对稀土冶炼分离企业管理和生产具有深远的现实意义.

关键词：蝴蝶突变危险程度安全生产保障系统离子型稀土冶炼分离