检索结果-南通市图书馆

Earthquake Research in China 2019年第2期33卷 265-275页

作者： GUO yang XU Jiajun LIN Chen JIN Xing YAO Huajian yang hongfeng CAI Huiteng Fujian Earthquake Agency Fuzhou 350003China School of Earth and Space Sciences University of Science and Technology of ChinaHefei 230026China School of Earth Sciences and Engineering Nanjing UniversityNanjing 210046China Earth System Science Programme Faculty of ScienceThe Chinese University of Hong KongHong Kong 999077China

112 short-period seismographs were set up in the 400 km^2 area of Pingtan Island and its surrounding areas in *** combined observations of the airgun source and ambient noise source were carried out using a dense array to receive the 387 airgun signals excited around the island and one month of continuous ambient noise *** 1-D P-wave and S-wave shallow velocity model of Pingtan Island is obtained by the inversion of the airgun body wave’s first arrival time data,and the reliability of the velocity model is verified by using the surface wave phase velocity dispersion curve,which can provide initial model for subsequent 3-D *** experimental results show that this experiment is a successful demonstration of local scale green non-destructive detection,which can provide basic data for shallow surface structure research and strong vibration simulation of the Pingtan Island.

关键词： Pingtan Island Fujian Dense array Airgun Ambient noise 1-D velocity model

Preface to the special issue of Dense Array Seismology

在线全文

学校读者我要写书评

暂无评论

Earthquake Science 2018年第5期31卷 225-226页

作者： Huajian Yao Baoshan Wang Xiaobo Tian hongfeng yang Xiaofeng Tian Laboratory of Seismology and Physics of Earth's Interior School of Earth and Space SciencesUniversity of Science and Technology of China Institute of Geology and Geophysics Chinese Academy of Sciences Earth System Science Programme The Chinese University of Hong Kong Geophysical Exploration Center China Earthquake Administration

Both earthquake seismology and structural seismology rely on observations, which in turn contribute critically to the development of seismology, especially in recent *** order to understand specific geologic structure... 详细信息

关键词： Preface to the special issue of Dense Array Seismology

ALS-linked C9orf72 dipeptide repeats inhibit starvation-induced autophagy through modulating BCL2–BECN1 interaction

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2024年第5期14卷 2026-2038页

作者： Shiqiang Xu Qilian Ma Junwen Shen Ningning Li Shan Sun Nana Wang yang Chen Chunsheng Dong Kin Yip Tam Jochen H.M.Prehn hongfeng Wang Zheng Ying Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences Soochow UniversitySuzhou 215123China MOE Key Laboratory of Geriatric Diseases and Immunology College of Pharmaceutical SciencesSuzhou Medical College of Soochow UniversitySuzhou 215123China Jiangsu Province Engineering Research Center of Precision Diagnostics and Therapeutics Development Soochow UniversitySuzhou 215123China Dept.of Physiology&Medical Physics and FUTURE-NEURO Research Centre Royal College of Surgeons in IrelandDublin D02 YN77Ireland Faculty of Health Sciences University of MacaoTaipaMacao 999078China Insititutes of Biology and Medical Science Soochow UniversitySuzhou 215123China

Growing evidences indicate that dysfunction of autophagy contributes to the disease pathogenesis of amyotrophic lateral sclerosis(ALS)and frontotemporal dementia(FTD),two neurodegenerative *** GGGGCC·GGCCCC repeat RNA expansion in chromosome 9 open reading frame 72(C9orf72)is the most genetic cause of both ALS and *** to the previous studies,GGGGCC·GGCCCC repeat undergoes the unconventional repeat-associated non-ATG translation,which produces dipeptide repeat(DPR)*** there is a growing understanding that C9orf72 DPRs have a strong ability to harm neurons and induce C9orf72-linked ALS/FTD,whether these DPRs can affect autophagy remains *** the present study,we find that poly-GR and poly-PR,two arginine-containing DPRs which display the most cytotoxic properties according to the previous studies,strongly inhibit starvation-induced ***,our data indicate that arginine-rich DPRs enhance the interaction between BCL2 and BECN1/Beclin 1 by inhibiting BCL2 phosphorylation,therefore they can impair autophagic clearance of neurodegenerative disease-associated protein aggregates under starvation condition in ***,our study not only highlights the role of C9orf72 DPR in autophagy dysfunction,but also provides novel insight that pharmacological intervention of autophagy using SW063058,a small molecule compound that can disrupt the interaction between BECN1 and BCL2,may reduce C9orf72 DPR-induced neurotoxicity.

关键词： Amyotrophic lateral sclerosis Frontotemporal dementia C9orf72 Autophagy BCL2 BECN1/Beclin 1 Dipeptide repeat Neurodegeneration

Fresh-Keeping Decision and Coordination of Fresh Agricultural Product Supply Chain Considering Carbon Cap-and-Trade under Different Dominance

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Systems Science and Systems Engineering 2024年第1期33卷 30-51页

作者： yang yang Guanxin Yao China Institute for Agricultural Equipment Industrial Development Jiangsu UniversityZhenjiang212013China Jiangsu Modern Logistics Research Base Yangzhou UniversityYangzhou225009China

In the context of low carbon,this paper discussed the impact of the carbon cap-and-trade policy on the fresh-keeping decision-making of two-echelon fresh agricultural product supply chains under different dominance,and designed cost-sharing contracts to coordinate the supply chain of fresh agricultural products dominated by suppliers and retailers *** results showed that:dominance has no effect on the fresh-keeping decision and total revenue of fresh agricultural product supply chain,but it affects the internal income distribution,and dominance does not always bring more benefits;the implementation of carbon cap-and-trade reduces the fresh-keeping decision-making of fresh agricultural products supply chain and reduces the free-rider income of followers;the role of higher carbon trading price is twofold,which not only brings about the speculation of leading enterprises,but also promotes the application of low-carbon technologies;consumers’high preference for freshness,low-cost and high-efficiency low-carbon technology are all conducive to improving the fresh-keeping efforts and benefits of the supply chain;cost-sharing contracts can coordinate the supply chain of fresh agricultural products.

关键词： Dominant power carbon cap-and-trade policy fresh agricultural product supply chain fresh-keeping decision-making

Overview of radar detection methods for low altitude targets in marine environments

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Systems Engineering and Electronics 2024年第1期35卷 1-13页

作者： yang Yong yang Boyu School of Electronic Science National University of Defense TechnologyChangsha 410073China

In this paper,a comprehensive overview of radar detection methods for low-altitude targets in maritime environments is presented,focusing on the challenges posed by sea clutter and multipath *** performance of the radar detection methods under sea clutter,multipath,and combined conditions is categorized and summarized,and future research directions are outlined to enhance radar detection performance for low-altitude targets in maritime environments.

关键词： radar sea clutter multipath scattering detection low altitude target

Fucosyltransferase 8 regulates adult neurogenesis and cognition of mice by modulating the Itga6-PI3K/Akt signaling pathway

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2024年第7期67卷 1427-1440页

作者： hongfeng Guo Qihang Sun Xiaoli Huang Xiaohao Wang Feng Zhang Wenzheng Qu Jinling Liu Xuejun Cheng Qiang Zhu Wen Yi Qiang Shu Xuekun Li The Children’s Hospital National Clinical Research Center for Child HealthSchool of MedicineZhejiang UniversityHangzhou 310052China The Institute of Translational Medicine School of MedicineZhejiang UniversityHangzhou 310029China College of Life Sciences Zhejiang UniversityHangzhou 310058China Binjiang Institute of Zhejiang University Hangzhou 310053China Zhejiang University Cancer Center Zhejiang UniversityHangzhou 310029China

Fucosyltransferase 8(Fut8)and core fucosylation play critical roles in regulating various biological processes,including immune response,signal transduction,proteasomal degradation,and energy ***,the function and underlying mechanism of Fut8 and core fucosylation in regulating adult neurogenesis remains *** have shown that Fut8 and core fucosylation display dynamic features during the differentiation of adult neural stem/progenitor cells(aNSPCs)and postnatal brain ***8 depletion reduces the proliferation of a NSPCs and inhibits neuronal differentiation of aNSPCs in vitro and in vivo,***,Fut8 deficiency impairs learning and memory in ***,Fut8 directly interacts with integrinα6(Itga6),an upstream regulator of the PI3kAkt signaling pathway,and catalyzes core fucosylation of *** of Fut8 enhances the ubiquitination of Itga6 by promoting the binding of ubiquitin ligase Trim21 to *** levels of Itga6 inhibit the activity of the PI3K/Akt signaling ***,the Akt agonist SC79 can rescue neurogenic and behavioral deficits caused by Fut8 *** summary,our study uncovers an essential function of Fut8 and core fucosylation in regulating adult neurogenesis and sheds light on the underlying mechanisms.

关键词： Fut8 adult neural stem/progenitor cells neurogenesis Itga6 PI3K/Akt

同方期刊数据库

Selective nano-buckling improves the performance of graphene logic transistors

在线全文

学校读者我要写书评

暂无评论

National Science Review 2024年第2期11卷 95-96页

作者： Tong yang Ming yang Department of Applied Physics The Hong Kong Polytechnic University Research Centre for Nanoscience and Nanotechnology The Hong Kong Polytechnic University

The massive integration of silicon-based transistors into modern electronic devices greatly increases power consumption and heat generation/dissipation[1]. In this concern, transistors based on atomically-thin graphene that exhibit high electric and thermoelectric conductivities with negligible contact resistance,

关键词：

Design Optimization and Operating Performance of S-CO_(2) Brayton Cycle under Fluctuating Ambient Temperature and Diverse Power Demand Scenarios

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2024年第1期33卷 190-206页

作者： yang Jingze yang Zhen DUAN Yuanyuan Key Laboratory for Thermal Science and Power Engineering of MOE Beijing Key Laboratory for CO_(2) Utilization and Reduction TechnologyTsinghua UniversityBeijing 100084China

The supercritical CO_(2)(S-CO_(2)) Brayton cycle is expected to replace steam cycle in the application of solar power tower system due to the attractive potential to improve efficiency and reduce *** the concentrated solar power plant with thermal energy storage is usually located in drought area and used to provide a dispatchable power output,the S-CO_(2) Brayton cycle has to operate under fluctuating ambient temperature and diverse power demand *** addition,the cycle design condition will directly affect the off-design *** this work,the combined effects of design condition,and distributions of ambient temperature and power demand on the cycle operating performance are analyzed,and the off-design performance maps are proposed for the first time.A cycle design method with feedback mechanism of operating performance under varied ambient temperature and power demand is introduced *** show that the low design value of compressor inlet temperature is not conductive to efficient operation under low loads and sufficient output under high ambient *** average yearly efficiency is most affected by the average power demand,while the load cover factor is significantly influenced by the average ambient *** multi-objective optimization,the optimal solution of designed compressor inlet temperature is close to the minimum value of35℃ in Delingha with low ambient temperature,while reaches 44.15℃ in Daggett under the scenario of high ambient temperature,low average power demand,long duration and large value of peak load during the peak temperature *** the cycle designed with compressor inlet temperature of 35℃ instead of 44.15℃ in Daggett under light industry power demand,the reduction of load cover factor will reach 0.027,but the average yearly efficiency can barely be improved.

关键词： supercritical CO_(2)Brayton cycle ambient temperature fluctuating power demand scenarios design optimization off-design performance

A physics-informed deep learning framework for spacecraft pursuit-evasion task assessment

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2024年第5期37卷 363-376页

作者： Fuyunxiang yang Leping yang Yanwei ZHU College of Aerospace Science and Engineering National University of Defense TechnologyChangsha 410073China

Qualitative spacecraft pursuit-evasion problem which focuses on feasibility is rarely studied because of high-dimensional dynamics,intractable terminal constraints and heavy computational *** this paper,A physics-informed framework is proposed for the problem,providing an intuitive method for spacecraft threat relationship determination,situation assessment,mission feasibility analysis and orbital game rules *** the first time,situation adjustment suggestions can be provided for the weak player in orbital ***,a dimension-reduction dynamics is derived in the line-of-sight rotation coordinate system and the qualitative model is determined,reducing complexity and avoiding the difficulty of target set presentation caused by individual ***,the Backwards Reachable Set(BRS)of the target set is used for state space partition and capture zone ***-time analysis can eliminate the influence of changeable initial state and enable the proposed framework to analyze plural situations ***,a time-dependent Hamilton-Jacobi-Isaacs(HJI)Partial Differential Equation(PDE)is established to describe BRS evolution driven by dimension-reduction dynamics,based on level set ***,Physics-Informed Neural Networks(PINNs)are extended to HJI PDE final value problem,supporting orbital game rules summarization through capture zone evolution ***,numerical results demonstrate the feasibility and efficiency of the proposed framework.

关键词： Spacecraft pursuit-evasion Qualitative differential game Physics-Informed Neural Networks(PINNs) Reachability analysis Hamilton-Jacobi-Isaacs(HJI) Partial Differential Equations(PDEs)

Processing,microstructure,and properties of porous ceramic composites with directional channels

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2024年第1期168卷 1-15页

作者： Bo Zhang yang yang Xueling Fan Key Laboratory of Service Performance and Protection Technology in Extreme Environments Xi’an Jiaotong UniversityXi’an 710049China State Key Laboratory for Strength and Vibration of Mechanical Structures School of Aerospace EngineeringXi’an Jiaotong UniversityXi’an 710049China

Porous ceramic composites with directional microchannels from micrometer to dozens of micrometer levels have attracted more and more attention in various fields including aerospace,biomedicines,and thermal insulation due to their excellent fluid permeability,mechanical properties,*** this article,we summarize the recent directional porous ceramics developments including their main processing routes and respective ***,the properties get from different processing routes have been com-pared and analyzed in terms of microstructures,mechanical properties,and *** has been given to the deeper understanding which can allow one to control the microstructural features of these porous ceramic composites to obtain the desired *** work can provide a useful reference for the development and application of porous ceramic composites with directional microchan-nels.

关键词： Porous ceramic composites Directional microchannels Processing routes Permeability