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Inhalation of Cananga odorata essential oil relieves anxiety behaviors in autism-like rats via regulation of serotonin and dopamine metabolism

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Journal of Integrative Medicine 2023年第2期21卷 205-214页

作者： Nan Zhang Shu-ting Wang lei yao School of Design Shanghai Jiao Tong UniversityShanghai 200000China School of Agriculture and Biology Shanghai Jiao Tong UniversityShanghai 200000China

Objective:Anxiety is one of the most common symptoms associated with autistic spectrum *** essential oil of Cananga odorata(Lam.)Hook.f.&Thomson,usually known as ylang-ylang oil(YYO),is often used in aromatherapy as a mood-regulating agent,sedative,or hypotensive *** the present study,the effects and mechanisms of YYO in alleviating anxiety,social and cognitive behaviors in autism-like rats were ***:The prenatal valproic acid(VPA)model was used to induce autism-like behaviors in offspring *** effectiveness of prenatal sodium valproate treatment(600 mg/kg)on offspring was shown by postnatal growth observation,and negative geotaxis,olfactory discrimination and Morris water maze(MWM)*** three treatment groups were formed with varying exposure to atomized YYO to explore the effects of YYO on the anxiety,social and cognitive behaviors of the autistic-like offspring through the elevated plus-maze test,three-chamber social test,and MWM ***,the monoamine neurotransmitters,including serotonin,dopamine and their metabolites,in the hippocampus and prefrontal cortex(PFC)of the rats were measured using a high-performance liquid ***:Offspring of VPA exposure rats showed autism-like *** the VPA offspring,mediumdose YYO exposure significantly elevated the time and entries into the open arms in the elevated plusmaze test,while low-dose YYO exposure significantly enhanced the social interaction time with the stranger rat in session 1 of the three-chamber social *** offspring treated with YYO exposure used less time to reach the platform in the navigation test of the MWM *** exposure significantly elevated the metabolism of serotonin and dopamine in the PFC of VPA ***:YYO exposure showed the effects in alleviating anxiety and improving cognitive and social abilities in the offspring of VPA exposure *** role of YYO was related to the regulation of the metabolism of serotonin

关键词： Cananga odorata essential oil autism-like rat anxiety social behavior monoamine neurotransmitter

Analysis of the Internal Characteristics of a De ector Jet Servo Valve

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Chinese Journal of Mechanical Engineering 2019年第2期32卷 180-192页

作者： Hao Yan Yukai Ren lei yao Lijing Dong School of Mechanical Electronic and Control Engineering Beijing Jiaotong University

In current research on deflector jet servo valves, the receiver pressure estimated using traditional two-dimensional simulation and theoretical calculation is always lower than the experimental data; therefore, credible information about the flow field in the prestage part of the valve can hardly be obtained. To investigate this issue and understand the internal characteristics of the deflector jet valve, a realistic numerical model is constructed and a three-dimensional simulation carried out that displays a complex flow pattern in the deflector jet structure. Then six phases of the flow pattern are presented, and the defects of the two-dimensional simulation are revealed. Based on the simulation results, it is found that the jet in the deflector has a longer core area and the fluid near the shunt wedge cannot resist the impact of the high-speed fluid. Therefore, two assumptions about the flow distribution are presented by which to construct a more complete theoretical model. The receiver pressure and prestage pressure gain are significantly enhanced in the calculations. Finally, special experiments on the prestage of the servo valve are performed, and the pressure performance of the numerical simulation and the theoretical calculation agree well with the experimental data. Finally, the internal mechanism described by the theoretical and numerical models is verified. From this research,more accurate numerical and theoretical models are proposed by which to figure out the internal characteristics of the deflector jet valve.

关键词： Deflector jet Servo valve Computational fluid dynamics(CFD) Numerical simulation

Effects of extract of Buddleja officinalis on partial inflammation of lacrimal gland in castrated rabbits with dry eye

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International Journal of Ophthalmology(English edition) 2010年第2期3卷 114-119页

作者： Xiao-lei yao, Hui-An Zhu Department of Ophthalmology the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine Changsha 410007 Hunan Province China Medical School of Nanhua University Hengyang421001 Hunan Province China

AIMTo assess the effects of extract of Buddleja officinalis on tear secretion volume, tear film stability, expressions of TGF-β1, IL-1β, TNF-α in lacrimal gland of castrated rabbits with dry eye.

关键词： dry eye lacrimal gland extract of buddleja officinalis androgen

Global Classical Solution for a Three-dimensional Viscous Liquid-gas Two-fluid Flow Model with Vacuum

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Acta Mathematicae Applicatae Sinica 2014年第4期30卷 989-1006页

作者： lei yao Jing YANG Zhen-hua GUO School of Mathematics and Center for Nonlinear Studies Northwest University

This is a continuation of the paper （J. Math. Phys., 52（2011）, 093102）. We consider the Cauchy problem to the three-dimensional viscous liquid-gas two-fluid flow model. The global existence of classical solution i... 详细信息

关键词： Viscous liquid-gas two-fluid flow model classical solution vacuum

A Note on the Adaptive Simpler Block GMRES Method

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Communications on Applied Mathematics and Computation 2019年第3期1卷 435-447页

作者： Qiaohua Liu lei yao Aijing Liu Department of Mathematics Shanghai UniversityShanghai 200444China School of Mathematical Sciences Qufu Normal UniversityQufu 273165Shandong ProvinceChina

The adaptive simpler block GMRES method was investigated by Zhong et al.(J Comput Appl Math 282:139-156, 2015) where the condition number of the adaptively chosen basis for the Krylov subspace was evaluated. In this paper, the new upper bound for the condition number is investigated. Numerical tests show that the new upper bound is tighter.

关键词： Large-scale nonsymmetric linear system Krylov subspace method Adaptive simpler block GMRES Condition number

Mechanical properties of Ti_(3)AlC_(2)ceramics before and after heat treatment

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Rare Metals 2022年第8期41卷 2777-2782页

作者： lei yao Chun-Cheng Zhu Jiu-Xing Jiang Bai-Bin Zhou Key Laboratory of Design and Synthesis of Functional Materials and Green Catalysis Harbin Normal UniversityHarbin150025China College of Applied Sciences Harbin University of Science and TechnologyHarbin150080China

Ti_(3)AIC_(2)ceramics were heat treated at the temperature from 1050 to 1450℃.Vickers hardness,fracture toughness,flexural strength and compressive strength of Ti_(3)AlC_(2)were tested and calculated before and after heat treatment,***_(3)AIC_(2)content,fracture toughness,flexural strength and compressive strength of Ti_(3)AIC_(2)first increase and then decrease,while Vickers hardness is just the opposite with the increase in temperature from 1050 to 1450℃*** heat treatment at1250℃,Ti_(3)AIC_(2)content reaches the highest level of94.2 wt%,and fracture toughness,flexural strength and compressive strength reach the maximum values,which are6.4 MPa·m^(1/2),318 MPa and 662 MPa,*** hardness reduces to the lowest value of 2.9 *** treatment does improve the strength and Ti_(3)AlC_(2)content,but reduces the hardness and optimizes the mechanical properties of Ti_(3)AlC_(2).

关键词： Ti_(3)AlC_(2) Heat treatment Mechanical properties

REVIEW ON MATHEMATICAL ANALYSIS OF SOME TWO-PHASE FLOW MODELS

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Acta Mathematica Scientia 2018年第5期38卷 1617-1636页

作者： Huanyao WEN lei yao Changjiang ZHU School of Mathematics South China University of TechnologyGuangzhou 510641China School of Mathematics and Center for Nonlinear Studies Northwest UniversityXi＇an 710127China

The two-phase flow models are commonly used in industrial applications, such as nuclear, power, chemical-process, oil-and-gas, cryogenics, bio-medical, micro-technology and so on. This is a survey paper on the study of compressible nonconservative two-fluid model, drift-flux model and viscous liquid-gas two-phase flow model. We give the research developments of these three two-phase flow models, respectively. In the last part, we give some open problems about the above models.

关键词： compressible nonconservative two-fluid model drift-flux model viscous liquid-gas two-phase flow model well-posedness

The detection of tetrahydrofuran hydrate formation and saturation using magnetic resonance imaging technique

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Journal of Natural Gas Chemistry 2010年第3期19卷 224-228页

作者： Yu Liu Yongchen Song Yongjun Chen lei yao Qingping Li Key Lab of Ocean Energy Utilization and Energy Conservation of Ministry of Education Dalian University of Technology Dalian 116024 Liaoning China Research Center of China National Offshore Oil Corporation Beijing 100027 China

Tetrahydrofuran（THF） hydrate was formed in bulk as well as in glass beads pack with a mean diameter of 3.0 mm by controlling the temperature under ambient *** of THF hydrate formation procedure were obtained using the magnetic resonance imaging（MRI） *** experiment results showed that MRI is an effective method for the detection of hydrate *** of hydrate formed both in bulk and glass beads can be confirmed by intensity integration of MRI images.

关键词： tetrahydrofuran hydrate magnetic resonance imaging glass beads saturation

Spatial Variability of PM_(2.5) Pollution in Imbalanced Natural and Socioeconomic Processes: Evidence from the Beijing-Tianjin-Hebei Region of China

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Chinese Geographical Science 2023年第1期33卷 161-174页

作者： WANG Yixu SUN Shuo XU Wentian FU Xuecheng yao lei College of Geography and Environment Shandong Normal UniversityJinan 250358China

Accurately identifying and quantifying the factors influencing PM_(2.5) pollution is of great significance for the prevention and control of pollution. However, the redundancy among potential factors of PM_(2.5) may be overlooked. Meanwhile, the inconsistent spatial distribution of the natural and socioeconomic conditions brings unique implications for the cities within a region, which may lead to an uncertain understanding of the relationship between pollution and environmental factors. This study focused on the Beijing-TianjinHebei(BTH) Region, China, which presents complex and varied background conditions. Potential impact factors on PM_(2.5) were firstly screened by combining systematic cluster analysis with a random forest recursive feature elimination algorithm. Then, the representative multi-factor responsible for PM_(2.5) pollution in the region during the key period of 2014–2018(when the strict national air pollution control policy was implemented). The results showed that the key driving factors of PM_(2.5) pollution in the BTH cities are different, indicating that the uniqueness of a city will have an impact on the leading causes of pollution. Further discussion shows that air control policy provides an effective way to improve air quality. This study aims to deepen the understanding of the risk drivers of air pollution within the BTH Region. In the future, it is recommended that more attention should be paid to the specific differences between the cities when formulating PM_(2.5) concentration control measures.

关键词： PM_(2.5) Beijing-Tianjin-Hebei Region multi-factor screening driving heterogeneity

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