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美国高校工程专业技术交流能力培养的研究和启示

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煤炭高等教育 2016年第5期34卷 23-27页

作者：蒋玉强姚建初中国矿业大学机电工程学院江苏徐州221116 美国东卡罗来纳大学工程系美国北卡莱罗那州27858

加强高校工程专业学生的交流能力培养是适应经济全球化发展和技术创新的需要。美国高校在培养体系建设和具体实践中积累了的若干成功经验,即多层面的重视和政策支持、大学期间多学年持续性培养、书面和口头交流能力并重、考核方式和教... 详细信息

加强高校工程专业学生的交流能力培养是适应经济全球化发展和技术创新的需要。美国高校在培养体系建设和具体实践中积累了的若干成功经验,即多层面的重视和政策支持、大学期间多学年持续性培养、书面和口头交流能力并重、考核方式和教学反馈规范细致,培养环境和要求贴近于工程现场等。结合目前我国高校工程教育发展形势,本研究在加强工程专业大学生技术交流能力培养的建设规划和实施方法上给出了相应的建议。

关键词：技术交流工程教育培养体系

一个工程系的创办和ABET评估认证:东卡罗来纳大学案例分享

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清华大学教育研究 2012年第4期33卷 65-72页

作者：姚建初保罗.考夫曼埃德.霍华德海登.格里芬东卡罗来纳大学工程系

从受评方的角度,总结了创办一个工程系和准备美国ABET工程技术专业认证的整个过程。首先对ABET和东卡罗来纳大学工程系进行必要的介绍,然后完整讲述了为准备ABET认证的组织协调,人员配置,评估计划书的制定,受评方与ABET的沟通,以及评估... 详细信息

从受评方的角度,总结了创办一个工程系和准备美国ABET工程技术专业认证的整个过程。首先对ABET和东卡罗来纳大学工程系进行必要的介绍,然后完整讲述了为准备ABET认证的组织协调,人员配置,评估计划书的制定,受评方与ABET的沟通,以及评估小组进校考察的前后过程。并且提供了课程-产出映射关系的具体实例。希望为中国工程教育同行今后准备此类认证工作提供实用的参考。

关键词：工程教育专业认证质量评估 ABET

A 63-Year-Old Male with D-Transposition of the Great Arteries Who Had an Early Form of the Arterial Switch Operation

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Congenital Heart Disease 2024年第1期19卷 65-68页

作者： Michael A.Rebolledo Jane S.yao jason N.Johnson Umar S.Boston Benjamin R.Waller III Division of Pediatric Cardiology Department of PediatricsThe University of Tennessee Health Science CenterThe Heart InstituteLe Bonheur Children’s HospitalMemphisUSA College of Medicine The University of Tennessee Health ScienceMemphisUSA Division of Pediatric Cardiothoracic Surgery Department of SurgeryThe University of Tennessee Health Science CenterHeart InstituteLe Bonheur Children’s HospitalMemphisUSA

We describe a 63-year-old male who appears to have undergone an early form of the arterial switch operation for D-transposition of the great arteries performed in the *** review the clinical and imaging data that support our *** had a diagnostic cardiac catheterization which demonstrated severe pulmonary hypertension responsive to epoprostenol and *** case may represent one example of the experimental surgical work done prior to *** Jatene’s description of theﬁrst successful arterial switch performed in 1975.

关键词： Adult congenital heart disease arterial switch operation great vessel anomaly imaging(all modalities)

Forest succession in post-agricultural Larix olgensis plantations in northeast China

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Journal of Forestry Research 2020年第6期31卷 2495-2505页

作者： Wei Ma Shen Lei Yujun Sun jason Grabosky Academy of Forest Inventory and Planning State Forestry AdministrationBeijing 100714China The Key Laboratory of Silviculture and Conservation of the Ministry of Education College of ForestryBeijing Forestry UniversityBeijing 100083China New Jersey Agricultural Experiment Station Rutgers UniversityNew BrunswickNJUSA

In order to understand the management of regional vegetation,numerical classification and ordination are widely used to investigate community distribution and vegetation *** particular,two-way indicator-species analysis programs(TWINSPAN)classifies plots and species into different ***-trended correspondence analysis(DCA)and canonical correspondence analysis(CCA)reflects the relationship between community and site *** with Larix olgensis *** is a suitable restoration strategy on post-agricultural fields in the Lesser Khingan *** results of this study show how these plantations develop over time to establish a reliable pathway model by measuring and clarifying the succession ***-eight *** plantations along a 48-year chronosequence of afforestation were investigated with a quadrat sampling *** composition,community structure attributes of diversity,and site conditions were *** were classified by TWINSPAN into five successional stages:immature,juvenile,mid-aged,nearmature and *** were validated by DCA and CCA *** conditions such as soil and litter thickness,soil organic matter,soil density,and pH were *** stages varied in community composition and species population,accompanied by time from afforestation and a gradient of site *** gradient showed changes in vegetation occurrence and diversity coinciding with changes in soil *** study showed that *** plantations had marked predominance in growth and were associated with improved soil fertility and the formation of a stable plant community.

关键词： Chronosequence Community structure Lesser Khingan Mountains Site conditions Species composition

Clinically relevant factors associated with quantitative optical coherence tomography angiography metrics in deep capillary plexus in patients with diabetes

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Eye and Vision 2020年第1期7卷 64-74页

作者： Fang yao Tang Erica O.Chan Zihan Sun Raymond Wong Jerry Lok Simon Szeto jason C.Chan Alexander Lam Clement C.Tham Danny S.Ng Carol Y.Cheung Department of Ophthalmology and Visual Sciences The Chinese University of Hong KongHong Kong Special Administrative RegionKowloonChina Hong Kong Eye Hospital Hong Kong Special Administrative RegionKowloonChina CUHK Eye Centre Hong Kong Eye Hospital147K Argyle StreetKlnKowloonHong KongChina

Background:To test clinically relevant factors associated with quantitative artifact-free deep capillary plexus(DCP)metrics in patients with diabetes mellitus(DM).Methods:563 eligible eyes(221 with no diabetic retinopathy[DR],135 with mild DR,130 with moderate DR,and 77 with severe DR)from 334 subjects underwent optical coherence tomography-angiography(OCT-A)with a swept-source OCT(Triton DRI-OCT,Topcon,Inc.,Tokyo,Japan).Strict criteria were applied to exclude from analysis those DCP images with artifacts and of poor quality,including projection artifacts,motion artifacts,blurriness,signal loss,B-scan segmentation error,or low-quality score.A customized MATLAB program was then used to quantify DCP morphology from the artifact-free DCP images by calculating three metrics:foveal avascular zone(FAZ),vessel density(VD),and fractal dimension(FD).Results:166(29.5%)eyes were excluded after quality control,leaving in the analysis 397 eyes(170 with no DR,101 with mild DR,90 with moderate DR,36 with severe DR)from 250 *** the multiple regression models,larger FAZ area was associated with more severe DR(β=0.687;p=0.037),shorter axial length(AL)(β=−0.171;p=0.003),thinner subfoveal choroid thickness(β=−0.122;p=0.031),and lower body mass index(BMI)(β=−0.090;p=0.047).Lower VD was associated with more severe DR(β=−0.842;p=0.001),shorter AL(β=0.107;p=0.039),and poorer visual acuity(VA)(β=−0.133;p=0.021).Lower FD was associated with more severe DR(β=−0.891;p<0.001)and with older age(β=−0.142;p=0.004).Conclusions:Quantitative artifact-free DCP metrics are associated with VA,DR severity,AL,subfoveal choroidal thickness,age,and BMI in diabetic *** effects of ocular and systemic factors should be considered for meaningful interpretations of DCP changes in DM patients.

关键词： Optical coherence tomography angiography Diabetic retinopathy Deep capillary plexus Visual acuity

Influence of Meniscal Attachments Placement on Articular Stress Deterioration

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Chinese Journal of Biomedical Engineering(English Edition) 2018年第4期27卷 144-150页

作者： yao Jie NIU Wen-xin Cheung jason Tak-Man ZHANG Ming FAN Yu-bo Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education School of Biological Science and Medical EngineeringBeihang University Beijing 100191 China Li Ning Sports Science Research Center Beijing 101100 China Department of Health Technology and Informatics Hong Kong Polytechnic University Hong Kong State Key Laboratory of Virtual Reality Technology and Systems Beihang University Beijing 100191 China

Meniscal attachments provide constraint for meniscus and contribute to knee stability. However, the influence of attachments placement on articular mechanical environment remains unclear. The present study aims to characterize the stress deterioration caused by abnormal attachment locations. Different placement of medial meniscal attachments were analyzed with a three-dimensional (3D) finite element (FE) model of knee joint. The articular stress distribution under compressive loadings indicates that abnormal placement of medial meniscal attachments could cause stress deterioration in meniscus and tibia plateau, which may increase the risk of OA. The influence of PMMA relocation was more severe than that of AMMA. The anterior displacement of both AMMA and PMMA could decrease the tibial contact area and therefore weakening the meniscal function of loading transmission. The present study provides an insight into the biomechanical character of meniscal attachments and may help improving the meniscal transplantation in the future.

关键词： meniscus attachment finite element stress knee

TSG-6对HCMV感染引起的TNF-α和IL-6表达水平的抑制作用

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中华微生物学和免疫学杂志 2016年第1期36卷 20-26页

作者：姚瑶张文昌赵俊张业婷钟峰甘霖俞海洋陈敬贤王明丽安徽医科大学微生物学教研室合肥230032 哥伦比亚大学病理与细胞生物学教研室纽约10032

目的研究肿瘤坏死因子α刺激基因-6（tumor necrosis factor α stimulated gene 6, TSG-6）在人巨细胞病毒（human cytomegalovirus, HCMV）感染所致的炎症过程中的作用及机制。方法用HCMV感染人胚肺成纤维细胞（MRC-5）和视网膜上皮... 详细信息

目的研究肿瘤坏死因子α刺激基因-6（tumor necrosis factor α stimulated gene 6, TSG-6）在人巨细胞病毒（human cytomegalovirus, HCMV）感染所致的炎症过程中的作用及机制。方法用HCMV感染人胚肺成纤维细胞（MRC-5）和视网膜上皮细胞（ARPE-19），并设正常细胞对照组和灭活病毒感染组。采用qRT-PCR和Western blot检测各组TSG-6 mRNA和蛋白表达水平。将重组人TSG-6蛋白（recombinant human TSG-6 protein, rhTSG-6） 100 ng/ml作用于HCMV感染的MRC-5细胞作为rhTSG-6干预组，采用ELISA方法检测细胞培养物上清中TNF-α和IL-6表达水平，用IFA及Western blot检测NF-κB核定位及其蛋白表达水平，并设正常细胞对照和病毒对照。结果HCMV感染MRC-5细胞72 h时，TSG-6 mRNA表达量为细胞对照组的19倍，在感染96 h时TSG-6 mRNA表达达高峰，为细胞对照组的376倍；HCMV感染ARPE-19细胞96 h时，TSG-6 mRNA表达量为细胞对照组的15倍，在120 h时为细胞对照组的354倍。Western blot结果证实，TSG-6蛋白表达水平在相应时间点也随之升高。rhTSG-6作用于HCMV感染的MRC-5细胞后与病毒对照组相比，TNF-α、IL-6水平明显下降（P〈0.05），且TSG-6能抑制核转录因子（nuclear factor-kappaB, NF-κB）的核移位及蛋白的表达。结论TSG-6参与HCMV引起的炎症反应，抑制HCMV相关炎性因子水平的表达并影响NF-κB的核定位。

关键词：人巨细胞病毒肿瘤坏死因子α刺激基因-6 核转录因子-κB

Localizing Effects of Leptin on Upper Airway and Respiratory Control during Sleep

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Localizing Effects of Leptin on Upper Airway and Respiratory...

GPS大气掩星技术在全球气候变化研究中的应用

第二届中国西部睡眠医学大会

作者： Qiaoling yao Huy Pho jason Kirkness Ellen E.Ladenheim Sheng Bi Timothy H.Moran David D.Fuller Paul J.Reiter David C.Bloom Alan R.Schwartz Vsevolod Y.Polotsky

Objectives Obesity hypoventilation syndrome and obstructive sleep apnea are common complications of obesity linked to defects in respiratory pump and upper airway neural *** deficient ob/ob mice have impaired hypercapnic ventilatory response and inspiratory flow limitation during sleep,which are both reversed with *** study is to localize CNS site（s） of leptin action on respiratory and upper airway neuro-ventilatory *** We localized the effect of leptin to medulla *** by administering intracerbroventricular leptin（10μg/2ul）vs vehicle to the lateral（n=14）vs fourth ventricle（n=11）of ob/ob mice followed by a 6 h polysomnographic *** were stratified for effects on respiratory（non-flow limited breaths） and upper airway（inspiratory flow limitation） *** loci were identified by（a） leptin-induced STAT3 phosphorylation and（b）projections of respiratory and upper airway motoneurons with a retrograde tracer pseudorabies *** Both routes of leptin administration increased minute ventilation during non-flow limited breathing in *** motoneurons projected to the nucleus of the solitary tract,which showed STAT3 phosphorylation,but not to the *** flow limitation and obstructive hypopneas were attenuated by leptin administration to the lateral,but not to the fourth cerebral *** airway motoneurons projected to the dorsomedial hypothalamus,which exhibited STAT3 *** Leptin relieves upper airway obstruction in sleep apnea by activating the forebrain,possibly in the dorsomedial *** contrast,leptin up-regulates ventilatory control through hindbrain sites of action,possibly in the nucleus of the solitary tract.

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地球物理学进展 2008年第3期23卷 722-730页

作者：虞南华朱文耀中国科学院上海天文台

人类活动引起全球变暖,衡量全球气候变化的指标有陆地、大气和海洋温度,水汽含量等等.研究对流层底层大气温度和水汽含量变化的传统方法是用数值天气预报模型和微波声纳,尚未实现用全球均匀覆盖的数据来做精确的定量研究.和GNSS系列卫... 详细信息

人类活动引起全球变暖,衡量全球气候变化的指标有陆地、大气和海洋温度,水汽含量等等.研究对流层底层大气温度和水汽含量变化的传统方法是用数值天气预报模型和微波声纳,尚未实现用全球均匀覆盖的数据来做精确的定量研究.和GNSS系列卫星计划比较,最近发射的COSMIC卫星气象探测数据的空间、时间以及垂直分辨率都大大提高.采用COSMIC数据可以改进和量化南极洲的大气压力模型,并综合GNSS系列卫星测量的水汽和温度剖面研究全球气候变化.用一维协方差算法估计南极洲及附近海洋的大气压、温度和湿度剖面.把COSMIC卫星密集测量期间演算得到的大气折射率和GNSS系列卫星的结果进行比较.再和独立测量数据进行比较,包括南极洲自动气象观测站资料,数值天气预报模型资料,多种测高卫星水汽资料和海洋表面温度资料以及区域GPS水汽图.上述工作将改进发展中的气象遥感技术并应用于天气预报和空间天气预报及全球气候变化研究.

关键词： GPS大气掩星技术全球气候变化水汽含量