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卫星及配套产品状态鉴定工作总体设计

西北工业大学学报 2019年第S01期37卷 64-67页

作者：胡振鑫郭昕阳姚惠生向日华北京跟踪与通信技术研究所北京100094 航天系统部装备部北京100094

目前卫星技术状态管理中存在订购方介入少、状态变化多、继承性差等问题,随着卫星研制由分散的定制试验品向批量的成熟产品转变,对卫星及配套产品的技术状态管理提出更高的要求。提出了由卫星订购方组织的对卫星状态鉴定概念,通过由单... 详细信息

目前卫星技术状态管理中存在订购方介入少、状态变化多、继承性差等问题,随着卫星研制由分散的定制试验品向批量的成熟产品转变,对卫星及配套产品的技术状态管理提出更高的要求。提出了由卫星订购方组织的对卫星状态鉴定概念,通过由单机到分系统再到整星层层递进的规范化状态鉴定申请、审查和审批程序,正式确定卫星的技术状态,作为同型号后续批次卫星生产和验收的依据,增强了订购方对卫星系统状态的管控,同时也有利于提升卫星单机的标准化、通用化水平。结合样例说明了卫星产品分级,以及各级产品状态鉴定的工作流程、审查审批单位和所需的文书,最后对开展卫星状态鉴定工作提出了建议。

关键词：卫星分级状态鉴定技术状态程序文书

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PBX炸药及其模拟材料冲击损伤的试验研究

弹箭与制导学报 2008年第1期28卷 131-134页

作者：梁增友黄风雷段卓平周栋姚惠生中北大学太原030051 北京理工大学北京100081

文中利用轻气炮驱动飞片加载技术对JO-9159炸药及其模拟材料样品进行了冲击加载,使其产生损伤,利用锰铜压阻计测量了试件的冲击压力。通过扫描电镜(SEM)对回收样品进行了显微观察,分析比较了炸药和模拟材料在冲击载荷作用下的损伤破坏... 详细信息

文中利用轻气炮驱动飞片加载技术对JO-9159炸药及其模拟材料样品进行了冲击加载,使其产生损伤,利用锰铜压阻计测量了试件的冲击压力。通过扫描电镜(SEM)对回收样品进行了显微观察,分析比较了炸药和模拟材料在冲击载荷作用下的损伤破坏模式。结果表明两者都具有脆性材料的损伤破坏特征,相对于PBX炸药模拟材料具有更明显的脆性特征。在细观上,PBX和模拟材料的损伤破坏模式是以微裂纹为主的脆性损伤,模拟材料的破坏主要表现为造型粉颗粒的破裂、破碎形成裂纹,而PBX炸药主要表现为颗粒之间的脱粘,并伴有颗粒的破碎。

关键词： PBX炸药炸药模拟材料损伤冲击载荷

Glycolytic dysregulation in Alzheimer's disease:unveiling new avenues for understanding pathogenesis and improving therapy

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Neural Regeneration Research 2025年第8期20卷 2264-2278页

作者： You Wu Lijie Yang Wanrong Jiang Xinyuan Zhang Zhaohui yao Department of Geriatrics Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina

Alzheimer's disease poses a significant global health challenge owing to the progressive cognitive decline of patients and absence of curative *** current therapeutic strategies,primarily based on cholinesterase inhibitors and N-methyl-Daspartate receptor antagonists,offer limited symptomatic relief without halting disease progression,highlighting an urgent need for novel research directions that address the key mechanisms underlying Alzheimer's *** studies have provided insights into the critical role of glycolysis,a fundamental energy metabolism pathway in the brain,in the pathogenesis of Alzheimer's *** in glycolytic processes within neurons and glial cells,including microglia,astrocytes,and oligodendrocytes,have been identified as significant contributors to the pathological landscape of Alzheimer's *** changes impact neuronal health and function,thus offering promising targets for therapeutic *** purpose of this review is to consolidate current knowledge on the modifications in glycolysis associated with Alzheimer's disease and explore the mechanisms by which these abnormalities contribute to disease onset and *** focus on the pathways through which glycolytic dysfunction influences Alzheimer's disease pathology should provide insights into potential therapeutic targets and strategies that pave the way for groundbreaking treatments,emphasizing the importance of understanding metabolic processes in the quest for clarification and management of Alzheimer's disease.

关键词： Alzheimer’s disease glial cells glycolysis neuronal metabolism pathogenesis therapeutic targets

The gut-eye axis:from brain neurodegenerative diseases to age-related macular degeneration

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Neural Regeneration Research 2025年第10期20卷 2741-2757页

作者： Qianzi Jin Suyu Wang Yujia yao Qin Jiang Keran Li Department of Ophthalmology The Affiliated Eye Hospital of Nanjing Medical UniversityNanjingJiangsu ProvinceChina The Fourth School of Clinical Medicine Nanjing Medical UniversityNanjingJiangsu ProvinceChina

Age-related macular degeneration is a serious neurodegenerative disease of the retina that significantly impacts ***,the specific pathogenesis remains unclear,and effective early treatment options are consequently *** microbiome is defined as a large ecosystem of microorganisms living within and coexisting with a *** intestinal microbiome undergoes dynamic changes owing to age,diet,genetics,and other *** dysregulation of the intestinal flora can disrupt the microecological balance,resulting in immunological and metabolic dysfunction in the host,and affecting the development of many *** recent decades,significant evidence has indicated that the intestinal flora also influences systems outside of the digestive tract,including the ***,several studies have demonstrated the critical role of the gut-brain axis in the development of brain neurodegenerative diseases,including Alzheimer’s disease and Parkinson’s ***,the role of the“gut-eye axis”has been confirmed to play a role in the pathogenesis of many ocular ***,age-related macular degeneration and many brain neurodegenerative diseases have been shown to share several risk factors and to exhibit comparable *** such,the intestinal flora may play an important role in age-related macular *** the above context,the present review aims to clarify the gut-brain and gut-eye connections,assess the effect of intestinal flora and metabolites on age-related macular degeneration,and identify potential diagnostic markers and therapeutic ***,direct research on the role of intestinal flora in age-related macular degeneration is still relatively limited,while studies focusing solely on intestinal flora are insufficient to fully elucidate its functional role in age-related macular ***-on-a-chip technology has shown promise in clarifying the gut-eye interactions,while integrating analysis of the inte

关键词： age-related macular degeneration biological agents blinding eye disease dietary nutrition fecal microbial transplantation gut-eye axis intestinal flora metabolite microecology neurodegenerative disease

Boosting Oxygen Evolution Reaction Performance on NiFe‑Based Catalysts Through d‑Orbital Hybridization

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Nano-Micro Letters 2025年第1期17卷 281-292页

作者： Xing Wang Wei Pi Sheng Hu Haifeng Bao Na yao Wei Luo State Key Laboratory of New Textile Materials and Advanced Processing Technology Key Laboratory of New Textile Materials and Applications of Hubei ProvinceSchool of Materials Science and EngineeringWuhan Textile UniversityWuhan 430200People’s Republic of China College of Chemistry and Molecular Sciences Wuhan UniversityWuhan 430072People’s Republic of China

Anion-exchange membrane water electrolyzers(AEMWEs)for green hydrogen production have received intensive attention due to their feasibility of using earth-abundant NiFe-based *** introducing a third metal into NiFe-based catalysts to construct asymmetrical M-NiFe units,the d-orbital and electronic structures can be adjusted,which is an important strategy to achieve sufficient oxygen evolution reaction(OER)performance in ***,the ternary NiFeM(M:La,Mo)catalysts featured with distinct M-NiFe units and varying d-orbitals are reported in this *** and theoretical calculation results reveal that the doping of La leads to optimized hybridization between d orbital in NiFeM and 2p in oxygen,resulting in enhanced adsorption strength of oxygen intermediates,and reduced rate-determining step energy barrier,which is responsible for the enhanced OER *** critically,the obtained NiFeLa catalyst only requires 1.58 V to reach 1 A cm^(−2) in an anion exchange membrane electrolyzer and demonstrates excellent long-term stability of up to 600 h.

关键词： NiFe-based catalysts d-orbital coupling Oxygen evolution reaction Anion exchange membrane electrolyzer

Highly conductive and stable iodine doped argyrodite electrolyte for all-solid-state lithium batteries

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Journal of Energy Chemistry 2025年第1期100卷 50-58页

作者： Gaozhan Liu Jing Zhang Jing Yang Jinghui Chen Xingyue Xiao Xiayin yao Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences

Lithium argyrodites with high ionic conductivity and low cost are considered as one of the most prospective solid electrolytes for all-solid-state lithium ***,the poor chemical stability and compatibility with lithium metal limit their ***,Li5.4PS4.4Cl1.4I0.2solid electrolyte with high ionic conductivity of 11.49 m S cm-1and improved chemical stability is synthesized by iodine *** ultra-thin Li5.4PS4.4Cl1.4I0.2membrane with thickness of 10μm can be obtained by wet coating process,exhibiting a high ionic conductivity of 2.09 mS cm-1and low areal resistance of 1.17Ω***,iodine doping could in-situ form LiI at the lithium/electrolyte interface and improve the critical current density of Li5.4PS4.4Cl1.6from 0.8 to 1.35 mA *** resultant LiCoO2/Li5.4PS4.4Cl1.4I0.2/Li battery shows excellent cycling stability at 1 C,with a reversible specific capacity of 110.1 mA h g-1and a retention of 80.5% after 1000 *** addition,the assembled LiCoO2/Li5.4PS4.4Cl1.4I0.2membrane/Li pouch cell delivers an initial discharge capacity of 110.4 mA h g-1and 80.5% capacity retention after 100 cycles.

关键词： Solid-State Batteries

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儿童原发性免疫缺陷病27例临床特点分析

中华实用儿科临床杂志 2014年第21期29卷 1652-1656页

作者：王佳姚慧生刘立云张晗李淼韩晓华中国医科大学附属盛京医院小儿呼吸内科沈阳110004

目的了解儿童原发性免疫缺陷病（PID）的临床特点，提高对该病的诊断率并予及时治疗，改善生活质量，延长存活时间。方法对2003年12月至2011年11月在中国医科大学附属盛京医院儿科病房住院且被诊断为PID的27例患儿临床资料进行回顾性分... 详细信息

目的了解儿童原发性免疫缺陷病（PID）的临床特点，提高对该病的诊断率并予及时治疗，改善生活质量，延长存活时间。方法对2003年12月至2011年11月在中国医科大学附属盛京医院儿科病房住院且被诊断为PID的27例患儿临床资料进行回顾性分析，记录病史、出生史、家族史、临床表现、实验室检查、诊断、治疗和转归等情况。结果27例PID患儿中以抗体缺陷为主的免疫缺陷病13例（48．15％），联合免疫缺陷病6例（22．22％），吞噬细胞数量和／或功能缺陷4例（14．81％），其他定义明确的免疫缺陷综合征4例（14．81％）。其共同特点为反复、严重、持久的感染，但病因不同，又有其各自的特点。24例临床表现为反复感染，感染部位主要是呼吸道，其次是中耳炎；有家族病史7例。病死率为37．04％（10／27例）。结论PID以抗体缺陷为主；部分类型有其独有特点，根据症状、体征可进行相应的检查以明确诊断；约25％的患儿有阳性家族史；病死率高。对反复感染，特别是反复患呼吸道感染或中耳炎的患儿，结合家族史，应尽早行免疫学检查，以早期识别和诊断PID。

关键词：原发性免疫缺陷病临床特点儿童

A Hybrid Approach for Pavement Crack Detection Using Mask R-CNN and Vision Transformer Model

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Computers, Materials & Continua 2025年第1期82卷 561-577页

作者： Shorouq Alshawabkeh Li Wu Daojun Dong yao Cheng Liping Li Faculty of Engineering China University of GeosciencesWuhan430074China

Detecting pavement cracks is critical for road safety and infrastructure *** methods,relying on manual inspection and basic image processing,are time-consuming and prone to *** deep-learning(DL)methods automate crack detection,but many still struggle with variable crack patterns and environmental *** study aims to address these limitations by introducing the Masker Transformer,a novel hybrid deep learning model that integrates the precise localization capabilities of Mask Region-based Convolutional Neural Network(Mask R-CNN)with the global contextual awareness of Vision Transformer(ViT).The research focuses on leveraging the strengths of both architectures to enhance segmentation accuracy and adaptability across different pavement *** evaluated the performance of theMaskerTransformer against other state-of-theartmodels such asU-Net,TransformerU-Net(TransUNet),U-NetTransformer(UNETr),SwinU-NetTransformer(Swin-UNETr),You Only Look Once version 8(YoloV8),and Mask R-CNN using two benchmark datasets:Crack500 and *** findings reveal that the MaskerTransformer significantly outperforms the existing models,achieving the highest Dice SimilarityCoefficient(DSC),precision,recall,and F1-Score across both ***,the model attained a DSC of 80.04%on Crack500 and 91.37%on DeepCrack,demonstrating superior segmentation accuracy and *** high precision and recall rates further substantiate its effectiveness in real-world applications,suggesting that the Masker Transformer can serve as a robust tool for automated pavement crack detection,potentially replacing more traditional methods.

关键词： Pavement crack segmentation transportation deep learning vision transformer Mask R-CNN image segmentation

A breakthrough of printable mesoscopic perovskite solar cells

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Science China Materials 2025年第1期 307-308页

作者： Zhiyi yao Zhijun Ning School of Physical Science and Technology Shanghai Tech University

High-performance solar cells based on low-cost wet coating methods are the much-anticipated technology for the next generation of photovoltaics. Perovskite solar cells (PSCs) provide a fascinating choice because their...

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