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CESSNA172飞机典型故障分析

民航学报 2025年第1期9卷 107-110+150页

作者：易思云杨兆军中国民用航空飞行学院

CESSNA172飞机是我国民航飞行员培训的主力初教机型之一。伴随着超高的使用率和飞机的老龄化,该型飞机陆续产生了各种故障。本文主要介绍该机在检修中发现的典型故障现象,对故障原因进行分析,并提出故障的预防或处理措施。

关键词： CESSNA172飞机典型故障故障原因故障预防处理措施

Weakness Ranking Method for Subsystems of Heavy-Duty Machine Tools Based on FMECA Information

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Chinese Journal of Mechanical Engineering 2021年第1期34卷 156-167页

作者： zhaojun yang Jinyan Guo Hailong Tian Chuanhai Chen Yongfu Zhu Jia Liu China Key Laboratory of CNC Equipment Reliability Ministry of EducationChangchun 130025China School of Mechanical and Aerospace Engineering Jilin UniversityChangchun 130025China College of Materials Science and Engineering Jilin UniversityChangchun 130025China School of Electrical and Mechanical Engineering Changchun University of Science and TechnologyChangchun 130025China

Heavy-duty machine tools are composed of many subsystems with different functions,and their reliability is governed by the reliabilities of these *** is important to rank the weaknesses of subsystems and identify the weakest subsystem to optimize products and improve their ***,traditional ranking methods based on failure mode effect and critical analysis(FMECA)does not consider the complex maintenance of ***,a weakness ranking method for the subsystems of heavy-duty machine tools is proposed based on generalized FMECA *** this method,eight reliability indexes,including maintainability and maintenance cost,are considered in the generalized FMECA ***,the cognition best worst method is used to calculate the weight of each screened index,and the weaknesses of the subsystems are ranked using a technique for order preference by similarity to an ideal ***,based on the failure data collected from certain domestic heavy-duty horizontal lathes,the weakness ranking result of the subsystems is obtained to verify the effectiveness of the proposed *** improved weakness ranking method that can comprehensively analyze and identify weak subsystems is proposed herein for designing and improving the reliability of complex electromechanical products.

关键词： Complex electromechanical products Weakness ranking method Failure mode effect and critical analysis(FMECA) Cognition best worst method(CBWM) Technique for order preference by similarity to an ideal solution(TOPSIS)

恩格列净联合甘精胰岛素治疗血糖控制不佳的2型糖尿病患者的效果

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中国医学创新 2025年第2期22卷 32-36页

作者：赖棠彬郭彩华杨昭君瑞金市中医院药剂科江西瑞金342500

目的:探究三种不同治疗方案对血糖控制不佳的2型糖尿病(T2DM)患者的效果。方法:纳入2022年3月—2023年10月瑞金市中医院102例血糖控制不佳的T2DM患者,使用随机数字表法分为三组,各34例。A组采用恩格列净联合甘精胰岛素治疗,B组采用达格... 详细信息

目的:探究三种不同治疗方案对血糖控制不佳的2型糖尿病(T2DM)患者的效果。方法:纳入2022年3月—2023年10月瑞金市中医院102例血糖控制不佳的T2DM患者,使用随机数字表法分为三组,各34例。A组采用恩格列净联合甘精胰岛素治疗,B组采用达格列净联合甘精胰岛素治疗,C组采用甘精胰岛素治疗。对比三组疗效、血糖指标[空腹血糖(FPG)、餐后2 h血糖(2 h PG)、糖化血红蛋白(HbA1c)]、血压[收缩压(SBP)和舒张压(DBP)]、胰岛功能[稳态胰岛素β细胞抵抗指数(HOMA-IR)、胰岛素β细胞分泌功能指数(HOMA-β)]、脂肪因子(脂联素、抵抗素和瘦素)及不良反应。结果:治疗12周后,A组FPG低于B组、C组,B组低于C组(P0.05)。结论:恩格列净联合甘精胰岛素方案对血糖控制不佳的T2DM疗效更优,可有效控制血糖,降低血压。

关键词： 2型糖尿病二肽基肽酶-4抑制剂达格列净甘精胰岛素血糖控制

氧化苦参碱对牙周膜干细胞干性标志物表达和成骨分化的作用

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中国组织工程研究 2025年第19期29卷 3992-3999页

作者：罗晶雍敏陈琦杨长怡赵恬马静梅冬兰虎金鹏杨昭君王钰然刘博宁夏医科大学口腔医学院宁夏回族自治区银川市750004 宁夏回族自治区干细胞与再生医学重点实验室宁夏回族自治区银川市750004 宁夏医科大学总医院口腔正畸科宁夏回族自治区银川市750004 宁夏医科大学总医院牙周病科宁夏回族自治区银川市750004

背景:人牙周膜干细胞是牙周再生组织工程潜在的功能细胞,然而长期体外培养会导致牙周膜干细胞干性减低并发生复制性衰老,从而影响其治疗效果。目的:探讨氧化苦参碱在体外对牙周膜干细胞干性维持和骨向分化的影响,并寻找潜在的影响机制... 详细信息

背景:人牙周膜干细胞是牙周再生组织工程潜在的功能细胞,然而长期体外培养会导致牙周膜干细胞干性减低并发生复制性衰老,从而影响其治疗效果。目的:探讨氧化苦参碱在体外对牙周膜干细胞干性维持和骨向分化的影响,并寻找潜在的影响机制。方法:采用组织块酶消化法从人牙周膜组织中分离、培养得到牙周膜干细胞,并使用流式细胞仪进行间充质细胞表面标志物鉴定。用0,2.5,5,10μg/mL氧化苦参碱孵育牙周膜干细胞,通过CCK8实验检测氧化苦参碱对牙周膜干细胞增殖活性的影响,筛选后续实验合适的药物质量浓度,采用Western blot检测牙周膜干细胞中干细胞非特异性蛋白SOX2和OCT4的表达,采用qRT-PCR、Western blot检测牙周膜干细胞中成骨相关基因和蛋白表达水平。结果与结论:①CCK8实验结果显示2.5μg/mL氧化苦参碱对牙周膜干细胞增殖活性有显著增强作用,后续实验选用2.5μg/mL氧化苦参碱进行干预;②与空白对照组相比,氧化苦参碱组牙周膜干细胞的干性标志物SOX2蛋白表达水平变化不明显(P>0.05),OCT4蛋白表达明显上调(P<0.05);③与成骨诱导组相比,氧化苦参碱+成骨诱导组牙周膜干细胞成骨相关基因ALP、RUNX2 mRNA表达及成骨相关蛋白ALP蛋白表达明显下调(P<0.05);④氧化苦参碱上调牙周膜干细胞干性标志物表达,抑制牙周膜干细胞骨向分化,高通量测序结果表明可能与WNT2、WNT16、COMP、BMP6有关。

关键词：牙周膜干细胞苦参碱类生物碱成骨细胞增殖氧化苦参碱干性维持高通量测序

Dopamine-mimetic-coated polyamidoamine-functionalized Fe_(3)O_(4) nanoparticles for safe and efficient gene delivery

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Frontiers of Materials Science 2023年第1期17卷 141-152页

作者： Liang Liu Chaobing Liu zhaojun yang Yiran Chen Xin Chen Jintao Guan College of Life Science and Technology Wuhan Polytechnic UniversityWuhan 430023China College of Chemistry and Environmental Engineering Wuhan Polytechnic UniversityWuhan 430023China

Fe_(3)O_(4) nanoparticles(NPs)are widely used in the construction of drug and gene delivery vectors because of their particular physicochemical *** modification can not only reduce the cytotoxicity of Fe_(3)O_(4),but also further improve the biocompatibility and delivery *** this work,firstly,polydopamine(PDA)-coated Fe_(3)O_(4) NPs(named Fe_(3)O_(4)@PDA)were prepared by using the self-polymerization characteristics of dopamine in alkaline ***,polyamidoamine(PAMAM)was modified by the Michael addition reaction to prepare water-soluble core shell magnetic NPs of Fe_(3)O_(4)@PDA@PAMAM,and its potential as gene vector was further *** results revealed that Fe_(3)O_(4)@PDA@PAMAM had the ability to condense and protect DNA,and showed lower cytotoxicity,higher cell uptake and transfection efficiency than those of *** has the potential to become a magnetic targeted gene vector for further study.

关键词： gene vector nanoparticle polydopamine gene transfection

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CESSNA172飞机机翼安装孔修理技术研究

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机械工程与自动化 2025年第1期54卷 217-219页

作者：易思云龙小辉杨兆军中国民航飞行学院飞机修理厂四川广汉618307

由于一架CESSNA172飞机机翼前梁安装孔磨损超标,为此介绍了一种该安装孔的修理技术,包括修理工装的设计、修理步骤的研究等。经验证,该技术是科学有效的。

关键词： CESSNA172飞机机翼安装孔修理技术

Stereo mapping of Ming Great Wall with remote sensing

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Chinese Science Bulletin 2010年第21期55卷 2290-2294页

作者： CHEN Jun JIN ShuPing LIAO AnPing ZHAO YouSong ZHANG HongWei RONG DaWei yang zhaojun National Geomatics Center of China Beijing 100830 China Chinese Academy of Culture Heritage Beijing 100029 China

Listed by UNESCO in 1987 as a World Heritage site,the world-famous Ming Great Wall stretches several thousands of kilometers across northern China,and served as a massive military defensive system which in recent times has a unique historical,artistic and scientific *** to historical reasons and lack of advanced technologies,construction resources and conservation status of Ming Great Wall have not been investigated in any systematic manner;indeed,the extent of the Great Wall has not even been *** has resulted in a shortage of reliable first-hand scientific information on actual size,spatially resource distribution and preservation status of this World Heritage *** by the urgent need to establish protection,research,renovation and management of Ming Great Wall,a comprehensive investigation and spatial mapping was jointly organized and completed by the State Bureau of Survey and Mapping and State Administration of Culture *** resolution digital stereo models at 1:10000 map scale covering the whole length of the Ming Great Wall have been created by photogrammetric reconstruction using nearly ten thousand aerial *** distribution and attributes of the wall sections,trenches and various subsidiary facilities in the surroundings of the Great Wall were measured with the help of digital photogrammetry workstations and results from field *** and precise information about the Ming Great Wall has now been obtained and documented,including surface lengths,resource distribution,and preservation *** example,the total length of Ming Great Wall is 8851.8 km,of which 6259.6 km is of actual wall,2232.5 km of natural terrain,and 359.7 km of *** category lengths,1828.8 km is constructed of stone,3411.3 km of earth,249.6 km in brick,197.5 km of cliff wall and the rest 572.4 km of other *** information provides the scientific basis and strong platform in helping to delineate areas needing protection,in planni

关键词：数字立体声测绘管理长城数字摄影测量工作站联合国教科文组织世界遗产遥感科学价值

A new risk measure customized for individual investors

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A new risk measure customized for individual investors

Real options with debt renegotiation of permanent coupon deduction

第十六届（2021）中国管理学年会

作者： Linjia Dong zhaojun yang School of Mathematics Harbin Institute of Technology Department of Finance Southern University of Science and Technology

FinTech makes numerous financial products accessible to individual investors but up to now,there is no risk measure method specially customized for individual investors instead of financial institutions which are generally too big to *** paper develops a hedging-based utility risk measure（HBU）*** show that HBU is a convex risk measure and if the utility has a constant relative risk aversion coefficient,HBU is also *** speaking,HBU is the opposite of a generalized utility indifference *** depends on claimants’ utility and the hedging instruments accessible to them and thus it is a personal（subjective） risk measure especially suitable for individual investors who need to have a comprehensive risk evaluation of a financial product.

关键词： Risk measures Personal risk measures Hedging risk Utility indifference prices

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Real options with debt renegotiation of permanent coupon ded...