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Non-linear relationship between combustion kinetic parameters and coal quality

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2012年第5期13卷 344-352页

作者： Jian-guo yang xiao-long ZHANG Hong ZHAO Li SHEN State Key Laboratory of Clean Energy Utilization Zhejiang University Hangzhou 310027 China

Combustion kinetic parameters(i.e.,activation energy and frequency factor) of coal have been proven to relate closely to coal properties;however,the quantitative relationship between them still requires further *** paper adopts a support vector regression machine(SVR) to generate the models of the non-linear relationship between combustion kinetic parameters and coal *** analyses on the thermo-gravimetry(TG) data of 80 coal samples were performed to prepare training data and testing data for the *** models developed were used in the estimation of the combustion kinetic parameters of ten testing *** predicted results showed that the root mean square errors(RMSEs) were 2.571 for the activation energy and 0.565 for the frequency factor in logarithmic form,*** curves defined by predicted kinetic parameters were fitted to the experimental data with a high degree of precision.

关键词： Kinetic parameter Coal property Thermo-gravimetry(TG) Support vector regression machine(SVR) Differential evolution

Expression analysis of chlorophyllid a binding protein a secretory, red fluorescence protein in the midgut of silkworm, Bombyx mori

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Insect Science 2014年第1期21卷 20-30页

作者： Lin Chen Rui yang xiao-long Hu Xing-Wei Xiang xiao-Feng Wu Institute of Sericulture and Apiculture College of Animal Sciences Zhejiang University Hangzhou China

Chlorophyllid a binding protein （ chbp） was recently characterized by its ability to bind the prosthetic group of chlorophylls and little information is known regarding its expression. In the present study, we found that chpb was expressed highly and exclusively in the midgut of silkworm, Bombyx mori. The expression level of chbp was very high in the newly molted fifth instar larvae followed by gradual decline in the same instar. Our results demonstrated that CHBP was a secretory protein and located mainly in the apical of midgut epithelial cells. Real-time polymerase chain reaction analysis results showed that chpb highly expressed in the anterior midgut, threefold and sixfold higher compared with that of the middle midgut and posterior midgut, respectively, and chpb expression declined in darkness. In addition, the expression of chbp was affected by high-dose virus or bacterium infection.

关键词： Bombyx mori chlorophyllid binding protein expression midgut

A Limited Deflection Routing Algorithm Based on Burst Loss Threshold in OBS Networks

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The Journal of China Universities of Posts and Telecommunications 2005年第3期12卷 44-48页

作者： WANG Ru- yan long Ke-ping WU Wei yang xiao-long ZHU Wei-le The College of Electronic Engineering University of Electronic Science and Technology of China Chengdu 610054 P. R China Special Research Centre for Optical Internet & Wireless Information Networks Chongqing Univ of Posts and Telecom Chongqing 400065 P.R. China

The deflection routing protocol is an effective contention resolution in Optical Burst Switching network, However, it can worsen loss performance of non-deflected burst on the deflection route. To improve the burst loss performance, a limited deflection routing scheme based on burst loss threshold is proposed to prevent injudicious deflection routing. By using threshold check function, it restrainedly allows the deflected burst to preemptive network resource, consequently, improve the QoS performance of non-deflected burst. Simulation results show that the scheme can efficiently prevent deflected burst contending with non-deflected burst on deflection route, and effectively improve the burst loss performance of entire networks.

关键词： optical burst switching deflection routing algorithm burst loss threshold threshold check function

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基于分层图的最少资源碎片AR-RWA算法

电子科技大学学报 2009年第4期38卷 529-532页

作者：阳小龙刘潇郑环电子科技大学通信与信息工程学院成都610054

提前预留模式是保障网格计算QoS的重要手段,但提前预留引起的资源碎片对资源利用率影响很大。该文分析了当前光网格中支持提前预留RWA算法存在的问题,即没有考虑资源碎片量及其对后来到达业务请求的影响。基于分层图模型,提出了最少资... 详细信息

提前预留模式是保障网格计算QoS的重要手段,但提前预留引起的资源碎片对资源利用率影响很大。该文分析了当前光网格中支持提前预留RWA算法存在的问题,即没有考虑资源碎片量及其对后来到达业务请求的影响。基于分层图模型,提出了最少资源碎片波长分配算法(即LG-LRF)。该算法将资源碎片作为分层图中波长平面的链路权值,尝试在分层图模型中对路由子问题和波长分配子问题一并解决,较大限度地避免波长连续性限制与资源碎片对后续业务的影响。通过仿真证明了其阻塞率、资源碎片率等性能有一定提高,适合工作于提前预留模式。

关键词：提前预留光网格资源碎片路由和波长分配

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认知无线电网络中授权用户参数估计

系统工程与电子技术 2015年第2期37卷 406-411页

作者：杨小龙谭学治哈尔滨工业大学电子与信息工程学院黑龙江哈尔滨150001

针对认知用户在频谱切换过程中无法实时地获取授权用户到达率与服务率的问题,提出了基于隐式马尔可夫模型的参数估计算法。首先利用排队论对授权用户队列进行建模与分析,推导出授权用户队列状态转移概率;其次利用能量感知算法检测授权... 详细信息

针对认知用户在频谱切换过程中无法实时地获取授权用户到达率与服务率的问题,提出了基于隐式马尔可夫模型的参数估计算法。首先利用排队论对授权用户队列进行建模与分析,推导出授权用户队列状态转移概率;其次利用能量感知算法检测授权用户队列真实状态,获得可观测序列值;然后利用隐式马尔可夫模型描述两种随机过程,即授权用户队列状态变化随机过程和可观测序列随机过程;最后利用forward-backward算法估计隐式马尔可夫模型,从而获得授权用户到达率与服务率。仿真结果表明,该方法能够实现实时的、较为精确的估计,从而实时地为认知用户选择频谱切换策略提供依据。

关键词：认知无线电网络频谱切换隐式马尔可夫过程

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速度估计模型在大涡模拟中的应用

计算力学学报 2007年第6期24卷 746-750页

作者：杨小龙符松清华大学航天航空学院北京100084 清华大学航天航空学院

介绍了速度估计模型的基本思想及其在物理空间的实现。速度估计模型依靠湍流大尺度的非线性作用估计出小尺度,从而可直接求解亚格子应力项而不需要额外的模型。本文采用该模型对不同雷诺数下的各向同性衰减湍流进行了模拟,并与直接数值... 详细信息

介绍了速度估计模型的基本思想及其在物理空间的实现。速度估计模型依靠湍流大尺度的非线性作用估计出小尺度,从而可直接求解亚格子应力项而不需要额外的模型。本文采用该模型对不同雷诺数下的各向同性衰减湍流进行了模拟,并与直接数值模拟、理论分析和其他亚格子模型的大涡模拟结果进行了比较。也初步考察了网格分辨率、不同精度的紧致格式对大涡模拟结果的影响。

关键词：速度估计模型大涡模拟亚格子模型湍流

Mutation analysis of APC gene in gastric cancer with microsatellite instability

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World Journal of Gastroenterology 2002年第5期8卷 787-791页

作者： Dian-Chun Fang Yuan-Hui Luo Shi-Ming yang xiao-An Li Xian-long Ling Li Fang Department of Gastroenterology,Southwest Hospital,Third Military Medical University,Chongqing 400038,China Department of Gastroenterology Southwest Hospital Third Military Medical University Chongqing 400038 China. fangdianchun@***

AIM: To evaluate the role of APC mutation in gastric carcinogenesis and to correlate APC mutation with microsatellite instability (MSI) in gastric carcinomas. METHODS: APC mutation was measured with multiplex PCR, denaturing gradient gel electrophoresis and DNA sequencing; and MSI was analyzed by PCR-based ***: Sixty-eight cases of sporadic gastric carcinoma were studied for APC mutation at exon 15 and MSI. APC mutaions were detected in 15(22.1%) gastric cancers. Frequence of APC mutation (33.3 %) in intestinal type of gastric cancer was significantly higher than that in diffuse type (13.1 %, P＜0.05).On the contrary, no association was observed betweerAPC mutation and tumor size,differentiation, depth of invasion, metastasis or clinical *** five microsatellite markers, MSI in at least one locus was detected in 17 of 68 (25 %) of the tumors *** mutations were all detected in MSI-L (only one locus,n＝9) or MSS(tumor lacking MSI or stable, n＝51), but no mutation was found in MSI-H (≥2 loci, n＝8).CONCLUSION: APC mutation is involved in carcinogenesis of intestinal type of gastric cancer and is independent of MSI phenotype but related to the LOH pathway in gastric cancer.

关键词：胃癌癌基因基因突变微卫星不稳定性

认知无线电网络中基于抢占式排队论的频谱切换模型

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物理学报 2015年第10期64卷 375-384页

作者：杨小龙谭学治关凯 f哈尔滨工业大学通信技术研究所哈尔滨150080

针对认知无线电网络中认知用户广义传输时间的优化问题,提出了一种基于抢占式续传优先权M/G/m排队理论的频谱切换模型.在该排队模型中,为了最小化认知用户广义传输时间,采用混合排队-并列式服务的排队方式.在此基础上,深入分析多个认知... 详细信息

针对认知无线电网络中认知用户广义传输时间的优化问题,提出了一种基于抢占式续传优先权M/G/m排队理论的频谱切换模型.在该排队模型中,为了最小化认知用户广义传输时间,采用混合排队-并列式服务的排队方式.在此基础上,深入分析多个认知用户、多个授权信道、多次频谱切换条件下认知用户信道使用情况,从而推导出广义传输时间表达式.最后探讨了该模型下自适应频谱切换策略.仿真结果表明,相比于已有的频谱切换模型,该模型不仅能够更加完整地描述认知用户频谱切换行为,而且使得认知用户传输时延更小,广义传输时间更短.此外,认知无线电网络允许的认知用户服务强度增加,能够容纳的认知用户数量增多.因此,该模型提升了认知用户频谱切换的性能,更好地实现了认知用户与授权用户的频谱共享.

关键词：认知无线电频谱切换广义传输时间排队理论

Tumor inflammation-specific self-amplifying fluorescent molecular probes induce an anti-tumor immune response

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Science China Chemistry 2025年第1期68卷 273-287页

作者： Shuguang yang Lijun Hu Hong xiao Zecong xiao Xintao Shuai PCFM Lab of Ministry of Education School of Materials Science and Engineering Sun Yat-sen University Department of Ultrasound The Fifth Affiliated Hospital Sun Yat-sen University Department of Medical Ultrasound The Third Affiliated Hospital of Sun Yat-sen University Nanomedicine Research Center The Third Affiliated Hospital of Sun Yat-sen University

Enhancing the concentration of exogenous molecular drugs within the tumor microenvironment through enzyme-catalyzed polymerization presents a novel strategy for cancer therapy. Nonetheless, the optimization of the catalytic efficiency is often impeded by the inefficient expression of enzymes. Herein, we reported a self-amplifying fluorescent molecular probe, Bis-HTPICG, for photodynamic therapy(PDT) and subsequent PDT-induced immunoreaction. The Bis-HTP-ICG probe possesses a noticeable enzyme-catalyzed polymerization facilitated by myeloperoxidase(MPO), a crucial enzyme secreted by neutrophils at inflammation sites. Upon exposure to laser irradiation, Bis-HTP-ICG showed a high PDT efficacy, inducing an acute inflammatory response that stimulates further recruitment of neutrophils and then elevated MPO secretion. The heightened level of MPO enhances the accumulation of the Bis-HTP-ICG via self-polymerization or binding with intratumoral proteins following MPO enzyme catalysis, instigating a self-amplifying chain reaction cycle involving Bis-HTP-ICG, neutrophils and ***, PDT efficiently incites immunogenic cell death(ICD) in tumor cells, initiating an anti-tumor immune response including dendritic cells(DCs) maturation, T cell proliferation and reprogramming of tumor-associated neutrophils(TANs). This work portrays a promising strategy for self-amplification of fluorescent molecular probes through adjustable enzyme levels,potentially offering a unique avenue to enhance the tumor accumulation of molecular drugs for improved tumor therapy.

关键词： fluorescent molecular probes self-amplifying myeloperoxidase photodynamic therapy