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Effect of Polynomial Expressed Distribution Dust Particles for Unmagnetized Two-Ion-Temperature Dusty Plasma

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Communications in Theoretical Physics 2009年第8期52卷 346-350页

作者： HE Guang-Jun LI xiao-Li LIN Mai-Mai shi yu-ren duan wen-shan Department of Physics Northwest Normal University Lanzhou 730070 China

Linear dispersion relation for linear wave and a Kadomtsev-Petviashvili (KP) equation for nonlinearwave are given for the unmagnetized two-ion-temperature cold dusty plasma with many different dust grain *** numerical results of variations of linear dispersion with respect to the different dust size distribution are ***,how the amplitude,width,and propagation velocity of solitary wave vary vs different dust size distribution isalso studied numerically in this paper.

关键词： polynomial expressed dust size distribution linear dispersion relation Kadomtsev-Petviashvili (KP) equation

Role of Th9 cells and Th17 cells in the pathogenesis of malignant ascites

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Asian Pacific Journal of Tropical Biomedicine 2015年第10期5卷 806-811页

作者： xian-wen yang Hai-Xing Jiang xiao-Li Huang shi-Jia Ma shan-yu Qin Department of Gastroenterology The First Affiliated Hospital of Guangxi Medical University

Objective: To assess the role of Th9 and Th17 cells in malignant ascites(MA).Methods: MA from 30 hepatic carcinoma patients and benign ascites from 30 cirrhotic patients were collected. Corresponding peripheral blood samples from these hepatic carcinoma and cirrhotic patients as well as 30 healthy subjects were collected. The frequency of Th9 and Th17 cells was tested by flow cytometry. Serum levels of interleukin(IL)-9 and IL-17 were examined by ***: The observed frequency of Th9 and Th17 cells, and the IL-9 and IL-17 serum levels were significantly higher in MA patients than those in cirrhotic patients and healthy control samples(P < 0.05). Moreover, the Th9 cells demonstrated positive correlation with Th17 cells as well as IL-9 in MA patients; however, this positive correlation was not observed in the cirrhotic patients or healthy control samples. The frequency of Th9 and Th17 cells was distinctly higher in MA patients presenting with stage III or IV malignancy and with lymph node or distant metastasis than those in patients in stage I or II and without distant metastasis(P < 0.05).Conclusions: The increased frequency of Th9 and Th17 cells in MA patients suggests that these two T cell subsets play a synergistic role in MA pathogenesis. This study also demonstrated that Th9 and Th17 cells may perform their biological functions in conjunction with IL-9 production.

关键词： ascites pathogenesis cirrhotic cytometry metastasi

Interleukin-22 ameliorates liver fibrogenesis by attenuating hepatic stellate cell activation and downregulating the levels of inflammatory cytokines

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World Journal of Gastroenterology 2015年第5期21卷 1531-1545页

作者： Dong-Hong Lu xiao-yun Guo shan-yu Qin Wei Luo xiao-Li Huang Mei Chen Jia-Xu Wang shi-Jia Ma xian-wen yang Hai-Xing Jiang Department of Gastroenterology The First Affiliated HospitalGuangxi Medical University

AIM:To investigate the effect of interleukin(IL)-22 onhepatic fibrosis in mice and the possible mechanism ***:Liver fibrosis was induced in male BALB/c mice by *** IL-22(rm IL-22) was administered intraperitoneally in CCl4-treated *** was assessed by histology and Masson *** activation of hepatic stellate cells(HSCs) was investigated by analysis of α-smooth muscle actin *** frequencies of T helper(Th) 22 cells,Th17 cells and Th1 cells,the expression of inflammatory cytokines [IL-22,IL-17 A,interferon-γ(IFN-γ),tumor necrosis factor-α(TNF-α),IL-6,IL-1b] and transcription factors [aryl hydrocarbon receptor(AHR),RAR-related orphan receptor(RORγt),T-bet] m RNA in the liver were *** addition,the plasma levels of IL-22,IL-17 A,IFN-γ,TNF-α,IL-6 and IL-1b were ***:Significant elevations in circulating Th22 cells,Th17 cells,Th1 cells,IL-22,IL-17 A,and IFN-γ were observed in the hepatic fibrosis group compared with the control group(P < 0.01).Treatment with rm IL-22 in mice with hepatic fibrosis ameliorated the severity of hepatic fibrosis,which was confirmed by lower hepatic fibrosis pathological scores(P < 0.01).Rm IL-22 decreased the frequencies of Th22 cells(6.71% ± 0.97% vs 8.09% ± 0.74%,P < 0.01),Th17 cells(4.34% ± 0.37% vs 5.71% ± 0.24%,P < 0.01),Th1 cells(3.09% ± 0.49% vs 4.91% ± 0.73%,P < 0.01),and the levels of IL-22(56.23 ± 3.08 vs 70.29 ± 3.01,P < 0.01),IL-17A(30.74 ± 2.77 vs 45.68 ± 2.71,P < 0.01),and IFN-γ(74.78 ± 2.61 vs 124.89 ± 2.82,P < 0.01).Down-regulation of IL-22,IL-17 A,IFN-γ,TNF-α,IL-6,IL-1b,AHR RORγt,and T-bet gene expression in the liver was observed in the rm IL-22 group(P < 0.01).CONCLUSION:The frequencies of Th22,Th17 andTh1 cells are elevated in hepatic *** IL-22 can attenuate HSC activation and down-regulate the levels of inflammatory cytokines,thereby ameliorating liver fibrogenesis.

关键词： T helper 22 cells T helper 17 cells T helper 1 cel

Balancing free and confined metallic Ni for an active and stable catalyst——A case study of CO methanation over Ni/Ni–Al2O3

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Journal of Energy Chemistry 2020年第11期29卷 73-84页

作者： Yong-shan xiao Yong-Hong Song Chang Liu xian-Ying shi Han-Qing Ge Min-Li Zhu Zhao-Tie Liu Zhong-wen Liu Key Laboratory of Syngas Conversion of Shaanxi Province School of Chemistry&Chemical EngineeringShaanxi Normal UniversityXi'an 710119ShaanxiChina

We propose a new strategy to make an active and stable Ni-based catalyst which can be operated in a wide range of reaction temperatures. The ordered mesoporous alumina(OMA) with confined Ni in the pore wall(Ni-OMA) was prepared via the one-pot evaporation induced self-assembly method. By using the incipient impregnation method, different amounts of free Ni were loaded over Ni-OMA(Ni/NiOMA) at a fixed total NiO content of 15 wt%. Characterization results confirmed the formation of wellstructured Ni-OMA, and the ordered structure was still well preserved even after impregnating NiO at a content of as high as 12 wt%. The catalysts were evaluated for the CO methanation as a model reaction under varied conditions. Importantly, the activity and stability of Ni/Ni-OMA for the titled reaction were significantly regulated by simply changing the ratio of the confined to free Ni. Over the optimum catalyst of NiO(2 wt%)/NiO(13 wt%)-OMA, the high activity at a temperature of as low as 300 ℃ was achieved with the space-time yield of methane over 7.6 g gcat-1 h-1 while a long-term stability for a time-onstream of 400 h was confirmed without an observable deactivation under the conditions of 600 ℃ and an extremely high gas hourly space velocity of 120,000 mL g-1 h-1. The results were well explained as the integrated merits of the free Ni for a high dispersion and the confined Ni in OMA for the anti-sintering property.

关键词： CO methanation Ni Ordered mesoporous alumina Evaporation induced self-assembly Ni-support interactions

Global, regional, and national burden of HIV-negative tuberculosis, 1990-2021: findings from the Global Burden of Disease Study 2021

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Infectious Diseases of Poverty 2024年第4期13卷 101-102页

作者： Shun-xian Zhang Feng-yu Miao Jian yang wen-Ting Zhou shan Lv Fan-Na Wei yu Wang xiao-Jie Hu Ping Yin Pei-Yong Zheng Ming yang Mei-TiWang Xin-yu Feng Lei duan Guo-Bing yang Ji-Chun Wang Zhen-Hui Lu Longhua Hospital Shanghai University of Traditional Chinese Medicine Shanghai 200032 China National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research) NHC Key Laboratory of Parasite and Vector Biology WHO Collaborating Centre for Tropical Diseases National Center for International Research On Tropical Diseases National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases Shanghai 200025 China School of Global Health Chinese Center for Tropical Diseases Research-Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Beijing Municipal Health Big Data and Policy Research Center Beijing Institute of Hospital Management Beijing 101100 China Department of Science and Technology Chinese Center for Disease Control and Prevention National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases Beijing 102206 China National Health Commission (NHC) Key Laboratory of Biosafety National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases Beijing 102206 China shanghai Mental Health Center Shanghai Jiao Tong University School of Medicine Shanghai 200032 China Gansu Provincial Center for Disease Control and Prevention Lanzhou 730000 China

Background Tuberculosis(TB)is a major infectious disease with significant public health *** widespread transmission,prolonged treatment duration,notable side effects,and high mortality rate pose severe *** study examines the epidemiological characteristics of TB globally and across major regions,providing a scientific basis for enhancing TB prevention and control measures *** The ecological study used data from the Global Burden of Disease(GBD)Study *** assessed new incidence cases,deaths,disability-adjusted life years(DALYs),and trends in age-standardized incidence rates(ASIRs),mortality rates(ASMRs),and DALY rates for drug-susceptible tuberculosis(DS-TB),multidrug-resistant tuberculosis(MDR-TB),and extensively drug-resistant tuberculosis(XDR-TB)from 1990 to 2021.A Bayesian age-period-cohort model was applied to project ASIR and *** In 2021,the global ASIR for all HIV-negative TB was 103.00 per 100,000 population 95%uncertainty interval(UI):92.21,114.91 per 100,000 populationl,declining by 0.40%(95%UI:-0.43,-0.38%)compared to *** global ASMR was 13.96 per 100,000 population(95%UI:12.61,15.72 per 100,000 population),with a decline of 0.44%(95%UI:-0.61,-0.23%)since *** global age-standardized DALY rate for HIV-negative TB was 580.26 per 100,000 population(95%UI:522.37,649.82 per 100,000 population),showing a decrease of 0.65%(95%UI:-0.69,-0.57 per 100,000 population)from *** global ASIR of MDR-TB has not decreased since 2015,instead,it has shown a slow upward trend in recent *** ASIR of XDR-TB has exhibited significant increase in the past 30 *** projections indicate MDR-TB and XDR-TB are expected to see signifcant increases in both ASIR and ASMR from 2022 to 2035,highlighting the growing challenge of drug-resistant *** This study found that the ASIR of MDR-TB and XDR-TB has shown an upward trend in recent *** reduce the TB burden,it is essential to enhance health infrastru

关键词： Tuberculosis Epidemiology Global burden of disease Sociodemographic Index

Epidemiological features and temporal trends of the co-infection between HIV and tuberculosis, 1990-2021: findings from the Global Burden of Disease Study 2021

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Infectious Diseases of Poverty 2024年第4期13卷 79-94页

作者： Shun-xian Zhang Ji-Chun Wang Jian yang shan Lv Lei duan Yan Lu Li-Guang Tian Mu-Xin Chen Qin Liu Fan-Na Wei Xin-yu Feng Guo-Bing yang Yong-Jun Li yu Wang xiao-Jie Hu Ming yang Zhen-Hui Lu Shao-Yan Zhang shi-Zhu Li Jin-Xin Zheng Longhua Hospital Shanghai University of Traditional Chinese MedicineShanghai 200032China National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research) NHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Centre for Tropical DiseasesNational Center for International Research on Tropical DiseasesNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious DiseasesShanghai 200025China Department of Science and Technology Chinese Center for Disease Control and PreventionNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious DiseasesBeIjing 102206China School of Global Health Chinese Center for Tropical Diseases Research-Shanghai Jiao Tong University School of MedicineShanghai 200025China Gansu Provincial Center for Disease Control and Prevention Lanzhou 730000China

Background The co-infection of human immunodeficiency virus(HIV)/acquired immune deficiency syndrome(AIDS)and tuberculosis(TB)poses a significant clinical challenge and is a major global public health *** study aims to elucidate the disease burden of HIV-TB co-infection in global,regions and countries,providing critical informa-tion for policy decisions to curb the HIV-TB *** The ecological time-series study used data from the Global Burden of Disease(GBD)Study *** data encompass the numbers of incidence,prevalence,mortality,and disability-adjusted life year(DALY),as well as age-standardized incidence rate(ASIR),prevalence rate(ASPR),mortality rate(ASMR),and DALY rate for HIV-infected drug-susceptible tuberculosis(HIV-DS-TB),HIV-infected multidrug-resistant tuberculosis(HIV-MDR-TB),and HIV-infected extensively drug-resistant tuberculosis(HIV-XDR-TB)from 1990 to *** 1990 to *** estimated annual percentage change(EAPC)of rates,with 95%confidence intervals(C/s),was *** In 2021,the global ASIR for HIV-DS-TB was 11.59 per 100,000 population(95%UI:0.37-13.05 per 100,000 population),0.55 per 100,000 population(95%UI:0.38-0.81 per 100,000 population),for HIV-MDR-TB,and 0.02 per 100,000 population(95%UI:0.01-0.03 per 100,000 population)for *** EAPC for the ASIR of HIV-MDR-TB and HIV-XDR-TB from 1990 to 2021 were 4.71(95%CI:1.92-7.59)and 13.63(95%CI:9.44-18.01),*** global ASMR for HIV-DS-TB was 2.22 per 100,000 population(95%UI:1.73-2.74 per 100,000 population),0.21 per 100,000 population(95%UI:0.09-0.39 per 100,000 population)for HIV-MDR-TB,and 0.01 per 100,000 population(95%UI:0.00-0.03 per 100,000 population)for HIV-XDR-TB in *** EAPC for the ASMR of HIV-MDR-TB and HIV-XDR-TB from 1990 to 2021 were 4.78(95%CI:1.32-8.32)and 10.00(95%Cl:6.09-14.05),*** The findings indicate that enhancing diagnostic and treatment strategies,strengthening healthcare infrastructure,increasing a

关键词： Co-infection Tuberculosis HIV/AIDS Epidemiology Global burden of disease 2021

SAPT:a synchrotron-based proton therapy facility in shanghai

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Nuclear Science and Techniques 2023年第10期34卷 36-46页

作者： Man-Zhou Zhang De-Ming Li Li-ren Shen Hai-Rong Zhang Zhi-Ling Chen Han-wen Du Ming Gu Rui Li De-Kang Liu yue-Hu Pu Jun-Feng yu Jian-Feng Chen Chu Chen Chun-Long Guo Hao Guo Ge-yang Jiang Zhi-Qiang Jiang Lin Jin wen-Jing Li Xiu-Fang Li Ye Lin Ming Liu Yong-Hao Liu Ya-Juan Liu Ming Lv Qing-Ru Mi Lian-Hua Ouyang Wei-Guo shi Hang Shu Qi-Sheng Tang Kun Wang Zhi-shan Wang Jun Wu xiao-Bing Wu Jia-Qiang Xu wen-Zhen Xu Chong-xian Yin Cheng yu ren-xian yuan Qi-Bing yuan Hai-Qun Zhang Miao Zhang wen-Zhi Zhang Li-Ying Zhao Wei-Min Zhou Shou-xian Fang Xi-Dong Sun Zhen-Tang Zhao shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201204China APACTRON Particle Equipment Co. Ltd.Shanghai 201815China The Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China

Because of its excellent dose distribution,proton therapy is becoming increasingly popular in the medical application of cancer treatment.A synchrotron-based proton therapy facility was designed and constructed in *** synchrotron,beam delivery system,and other technical systems were commissioned and reached their expected *** a clinical trial of 47 patients was finished,the proton therapy facility obtained a registration certificate from the National Medical Products *** characteristics of the accelerator and treatment systems are described in this article.

关键词： Proton therapy Synchrotron Slow extraction Gantry Beam delivery system

Towards the full realization of the RIBLL2 beam line at the HIRFL-CSR complex

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Science Bulletin 2018年第2期63卷 78-80页

作者： Bao-Hua Sun Jian-Wei Zhao Xue-Heng Zhang Li-Na Sheng Zhi-yu Sun Isao Tanihata Satoru Terashima Yong Zheng Li-Hua Zhu Li-Min duan Liu-Chun He Rong-Jiang Hu Guang-Shuai Li wen-Jian Lin Wei-Ping Lin Chuan-Ye Liu Zhong Liu Chen-Gui Lu Xin-wen Ma Li-Jun Mao Yi Tian Feng Wang Meng Wang shi-Tao Wang Jia-wen Xia xiao-Dong Xu Hu-shan Xu Zhi-Guo Xu Jian-Cheng yang Da-yu Yin You-Jin yuan wen-Long Zhan yu-Hu Zhang xiao-Hong Zhou School of Physics and Nuclear Energy Engineering Beihang University Beijing 100191 China International Research Center for Nuclei and Particles in the Cosmos Beijing 100191 China Institute of Modern Physics Chinese Academy of Sciences Lanzhou 730000 China

More than 99%of the mass in the visible universe—the material that makes up ourselves,our planet,stars—is in the atomic *** the matter has existed for billions of years,only over the past few decades have we had the tools and the knowledge necessary to get a basic understanding of the structure and dynamic of *** physicists around the world have made tremendous strides by initiating a broad range of key

关键词： HIRFL-CSR 横梁建筑群排队原子核物理学家试验性世界

Impacts of smoking status on the clinical outcomes of coronary non-target lesions in patients with coronary heart disease:a single-center angiographic study

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Chinese Medical Journal 2020年第19期133卷 2295-2301页

作者： Hao-Bo Xu Juan Wang Ji-Lin Chen Chao Guo Jian-Song yuan Xin duan Feng-Huan Hu Wei-xian yang xiao-Liang Luo Rong Liu Jin-Gang Cui Sheng-wen Liu xiao-Jin Gao yu-shi Chun Shu-Bin Qiao Department of Cardiology Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical SciencesBeijing 100037China

Background:Coronary atherosclerotic plaque could go through rapid progression and induce adverse cardiac *** study aimed to evaluate the impacts of smoking status on clinical outcomes of coronary non-target ***:Consecutive patients with coronary heart disease who underwent two serial coronary angiographies were *** coronary non-target lesions were recorded at first coronary angiography and analyzed using quantitative coronary angiography at both *** were grouped into non-smokers,quitters,and smokers according to their smoking *** outcomes including rapid lesion progression,lesion re-vascularization,and myocardial infarction were recorded at second coronary *** Cox regression analysis was used to investigate the association between smoking status and clinical ***:A total of 1255 patients and 1670 lesions were *** were younger and more likely to be male compared with non*** in percent diameter stenosis was significantly lower(2.7[0.6,7.1]%vs.3.5[0.9,8.9]%)and 3.4[1.1,7.7]%,P=0.020)in quitters than those in smokers and *** tended to have a decreased incidence of rapid lesions progression(15.8%[76/482]vs.21.6%[74/342]and 20.6%[89/431],P=0.062),lesion re-vascularization(13.1%[63/482]vs.15.5%[53/432]and 15.5%[67/431],P=0.448),lesion-related myocardial infarction(0.8%[4/482]vs.2.6%[9/342]and 1.4%[6/431],P=0.110)and all-cause myocardial infarction(1.9%[9/482]vs.4.1%[14/342]and 2.3%[10/431],P=0.128)compared with smokers and *** multivariable analysis,smoking status was not an independent predictor for rapid lesion progression,lesion re-vascularization,and lesion-related myocardial infarction except that a higher risk of all-cause myocardial infarction was observed in smokers than non-smokers(hazards ratio:3.00,95%confidence interval:1.04-8.62,P=0.042).Conclusion:Smoking cessation mitigates the increase in percent diameter stenosis

关键词： Smoking status Coronary non-target lesion Rapid progression Re-vascularization Myocardial infarction