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Student Academic Performance Predictive Model Based on Dual-stream Deep Network

计算机科学 2024年第10期51卷 119-128页

作者： XIE Hui ZHANG Pengyuan DONG Zexiao yang Huiting KANG Huan HE Jiangshan CHEN Xueli Center for Biomedical-photonics and Molecular Imaging Xi’an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life InformationSchool of Life Science and TechnologyXidian UniversityXi’an 710126China Engineering Research Center of Molecular and Neuro Imaging Ministry of EducationXi’an 710126China Innovation Center for Advanced Medical Imaging and Intelligent Medicine Guangzhou Institute of TechnologyXidian UniversityGuangzhou 510550China

Blended teaching is one of the essential teaching methods with the development of information *** a learning effect evaluation model is helpful to improve students’academic performance and helps teachers to better implement course ***,a lack of evaluation models for the fusion of temporal and non-temporal behavioral data leads to an unsatisfactory evaluation *** meet the demand for predicting students’academic performance through learning behavior data,this study proposes a learning effect evaluation method that integrates expert perspective indicators to predict academic performance by constructing a dual-stream network that combines temporal behavior data and non-temporal behavior data in the learning *** this paper,firstly,the Delphi method is used to analyze and process the course learning behavior data of students and establish an effective evaluation index system of learning behavior with universality;secondly,the Mann-Whitney U-test and the complex correlation analysis are used to analyze further and validate the evaluation indexes;and lastly,a dual-stream information fusion model,which combines temporal and non-temporal features,is *** learning effect evaluation model is built,and the results of the mean absolute error(MAE)and root mean square error(RMSE)indexes are 4.16 and 5.29,*** study indicates that combining expert perspectives for evaluation index selection and further fusing temporal and non-temporal behavioral features that for learning effect evaluation and prediction is rationality,accuracy,and effectiveness,which provides a powerful help for the practical application of learning effect evaluation and prediction.

关键词： Blended teaching Expert perspective indicators Two-stream information fusion model

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Asialoglycoprotein receptor 1 promotes SARS-CoV-2 infection of human normal hepatocytes

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Signal Transduction and Targeted Therapy 2024年第3期9卷 1199-1208页

作者： Xinyi yang Xu Zheng Yuqi Zhu Xiaying Zhao Jun Liu Jiangna Xun Songhua Yuan Jun Chen Hanyu Pan Jinlong yang Jing Wang Zhimin Liang Xiaoting Shen Yue Liang Qinru Lin Huitong Liang Min Li Fei Peng Daru Lu Jianqing Xu Hongzhou Lu Shibo Jiang Ping Zhao Huanzhang Zhu State Key Laboratory of Genetic Engineering and Engineering Research Center of Gene Technology Ministry of EducationInstitute of GeneticsSchool of Life SciencesYiwu Research InstituteFudan UniversityShanghaiChina Department of Microbiology Faculty of Naval MedicineNaval Medical UniversityShanghai 200433China Scientific Research Center Shanghai Public Health Clinical CenterFudan UniversityShanghaiChina Department of Infectious Diseases and Immunology Shanghai Public Health Clinical CenterFudan UniversityShanghaiChina Changzheng Hospital Naval Medical UniversityShanghaiChina Key Laboratory of Medical Molecular Virology(MOE/NHC/CAMS) Shanghai Institute of Infectious Disease and BiosecuritySchool of Basic Medical SciencesFudan UniversityShanghaiChina Department of Infectious Diseases and Nursing Research Institution National Clinical Research Center for Infectious DiseasesThe Third People’s Hospital of ShenzhenShenzhenGuangdongChina

Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)causes multi-organ damage,which includes hepatic dysfunction,as observed in over 50%of COVID-19 *** I converting enzyme(peptidyl-dipeptidase A)2(ACE2)is the primary receptor for SARS-CoV-2 entry into host cells,and studies have shown the presence of intracellular virus particles in human hepatocytes that express ACE2,but at extremely low ***,we asked if hepatocytes might express receptors other than ACE2 capable of promoting the entry of SARS-CoV-2 into *** address this question,we performed a genome-wide CRISPR-Cas9 activation library screening and found that Asialoglycoprotein receptor 1(ASGR1)promoted SARS-CoV-2 pseudovirus infection of HeLa *** Huh-7 cells,simultaneous knockout of ACE2 and ASGR1 prevented SARS-CoV-2 pseudovirus *** the immortalized THLE-2 hepatocyte cell line and primary hepatic parenchymal cells,both of which barely expressed ACE2,SARSCoV-2 pseudovirus could successfully establish an ***,after treatment with ASGR1 antibody or siRNA targeting ASGR1,the infection rate significantly dropped,suggesting that SARS-CoV-2 pseudovirus infects hepatic parenchymal cells mainly through an ASGR1-dependent *** confirmed that ASGR1 could interact with Spike protein,which depends on receptor binding domain(RBD)and N-terminal domain(NTD).Finally,we also used Immunohistochemistry and electron microscopy to verify that SARS-CoV-2 could infect primary hepatic parenchymal *** inhibiting ASGR1 in primary hepatic parenchymal cells by siRNA,the infection efficiency of the live virus decreased ***,these findings indicate that ASGR1 is a candidate receptor for SARS-CoV-2 that promotes infection of hepatic parenchymal cells.

关键词： ACE2 infection glycoprotein

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Albumen/Gelatin Bio-Inks Preparation in 3D Bio-Printing for in situ Tissue Culture of Cultured Meat

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Food Science and Human Wellness 2024年

作者： Xiang Guo Feng yang Yu Qi Yingying Li Shouwei Wang Baohua Kong China Meat Research Center College of Food Science， Northeast Agricultural University

3D bio-printing is an emerging tissue engineering technology， and its printing parameters have been upgraded to enable in-depth application in cell-cultured meat. However， excellent printable and edible bio-inks for cell-cultured meat are in urgent need of development. Therefore， a low-cost bio-ink based on albumin and gelatin was developed. At first， suitable printability of the bio-ink was determined by rheology analysis， excellent mechanical stability， and excellent mechanical stability of the printed scaffold was also proved by water absorption and degradation rate. Next， the biocompatibility of the scaffold and its interaction with cells were clarified through cell proliferation culture， cell status research and omics analysis. Notably， AG7 demonstrated better printability and AGS7 provided better conditions for cell attachment， proliferation and migration， "S"-shaped exponential growth curve further revealed the significant advantages of AGS7 scaffolds in cell culture. More importantly， the tissue culture process of muscle cells was simulated to organoid culture， which elucidated the interaction information between cells and scaffolds. This work has filled the vacancy in the industry and provides a novel strategy for the development of production of cell cultured meat.

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国土空间用途管制对中国经济高质量发展的影响研究——基于强度和效度视角

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自然资源学报 2024年第3期39卷 508-527页

作者：张扬大连民族大学经济管理学院大连116600

基于地理探测器等方法,使用2010—2021年省级面板数据,从强度和效度视角研究国土空间用途管制对中国经济高质量发展的影响。得出以下研究结果:(1)国土空间用途管制强度对经济高质量发展有显著影响,因子影响力为0.089;(2)国土空间用途管... 详细信息

基于地理探测器等方法,使用2010—2021年省级面板数据,从强度和效度视角研究国土空间用途管制对中国经济高质量发展的影响。得出以下研究结果:(1)国土空间用途管制强度对经济高质量发展有显著影响,因子影响力为0.089;(2)国土空间用途管制效度对经济高质量发展具有显著影响,因子影响力为0.406;(3)全国、东部、中部、西部和东北地区的国土空间用途管制强度位于6.29~7.46、7.14~8.66、6.22~6.94、7.72~9.11和3.59~4.29区间时,经济高质量发展均值最高。研究认为科学实施国土空间用途管制,可以推动中国经济高质量发展,提出了保持国土空间用途管制最优强度区间与完善补偿机制、提升国土空间用途管制效度、有针对性地拟定各地区经济高质量发展实施方案的建议。

关键词：地理探测器国土空间用途管制经济高质量发展

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An inversely designed integrated spectrometer with reconfigurable performance and ultra-low power consumption

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Opto-Electronic Advances 2024年第8期7卷 43-54页

作者： Ang Li Yifan Wu Chang Wang Feixia Bao Zongyin yang Shilong Pan National Key Laboratory of Microwave Photonics Nanjing University of Aeronautics and AstronauticsNanjing 210016China Key Lab of Modern Optical Technologies of Education Ministry of China Soochow UniversitySuzhou 215006China College of Information Science and Electronic Engineering Zhejiang UniversityHangzhou 310058China

Despite the pressing demand for integrated spectrometers,a solution that deliver high-performance while being practically operated is still ***,current integrated spectrometers lack reconfigurability in their performance,which is highly desirable for dynamic working *** study presents a viable solution by demonstrating a userfriendly,reconfigurable spectrometer on *** the core of this innovative spectrometer is a programmable photonic circuit capable of exhibiting diverse spectral responses,which can be significantly adjusted using on-chip phase *** distinguishing feature of our spectrometer lies in its inverse design approach,facilitating effortless control and efficient manipulation of the programmable *** eliminating the need for intricate configuration,our design reduces power consumption and mitigates control ***,our reconfigurable spectrometer offers two distinct operating *** the Ultra-High-Performance mode,it is activated by multiple phase-shifters and achieves exceptional spectral resolution in the picometer scale while maintaining broad *** the other hand,the Ease-of-Use mode further simplifies the control logic and reduces power consumption by actuating a single-phase *** this mode provides a slightly degraded spectral resolution of approximately 0.3 nm,it prioritizes ease of use and is wellsuited for applications where ultra-fine spectral reconstruction is not a primary requirement.

关键词： silicon photonics integrated spectrometers computational spectrometers

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解开西安城墙历史保护的成功密码

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城市规划 2024年第4期48卷 104-112页

作者：于洋中国人民大学公共管理学院城市规划与管理系中国城市规划学会规划实施分会

西安城墙是我国目前规模最大、保护最完整的古城垣,在20世纪下半叶经历了历次拆城浪潮后成功保留至今,不得不说是一个奇迹,是我国在遗产保护领域为数不多的具有成功经验的代表。在对西安城墙保护历程回顾的基础上,本文将详细剖析保护规... 详细信息

西安城墙是我国目前规模最大、保护最完整的古城垣,在20世纪下半叶经历了历次拆城浪潮后成功保留至今,不得不说是一个奇迹,是我国在遗产保护领域为数不多的具有成功经验的代表。在对西安城墙保护历程回顾的基础上,本文将详细剖析保护规划得以顺利实施背后的深层次原因,并思考其中的得失。希望通过对这段尘封历史的探寻与反思,能够起到以史为镜的作用,推动我国文化遗产保护事业进一步发展。

关键词：保护历程规划实施西安城墙反思与启示

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Aerobic respiration Lactococcus lactis ameliorate Salmonella induced infection and intestinal dysfunctions by oxygen-scavenging and maintaining immune balance and regulating intestinal microbiota

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Food Science and Human Wellness 2024年

作者： Yulong Zhang Han yang Zhiliang Cheng Hui Ha Fei Liu Yuehua Jiao Key Laboratory of Dairy Science， Ministry of Education， Food College， Northeast Agricultural University Center of Drug Safety Evaluation， Heilongjiang University of Chinese Medicine

Salmonella grows better under aerobic conditions as a facultative anaerobic foodborne pathogenic bacteria. The oxygen-scavenging activity of Lactococcus lactis in the intestinal tract is a promising strategy for preventing Salmonella infection. In this study， the aerobic respiration requirement and preventive mechanism of Lactococcus lactis subsp. lactis (L. lactis) KLDS 4.0325 in murine models infected by Salmonella enterica subsp. enterica serovar Typhimurium (S. Typhimurium) SL1344 were investigated. Results indicate that L. lactis KLDS 4.0325 is capable of aerobic respiratory metabolism in the host intestine when exogenous heme exists， and decrease intestinal oxygen concentration， which in turn trigger autophagy of intestinal cells to reduce S. Typhimurium load， improve gut microbiota composition， alleviate intestinal barrier injury and inflammation response. These results suggest that aerobic respiration L. lactis KLDS 4.0325 can prevent S. Typhimurium infection in a new way in which by restoring intestinal cell hypoxia， maintaining immune balance and regulating intestinal flora.

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Research on Track Fastener Service Status Detection Based on Improved Yolov4 Model

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Journal of Transportation Technologies 2024年第2期14卷 212-223页

作者： Jing He Weiqi Wang Nengpu yang College of Electrical and Information Engineering Hunan University of Technology Zhuzhou Hunan College of Railway Transportation Hunan University of Technology Zhuzhou Hunan

As an important part of railway lines, the healthy service status of track fasteners was very important to ensure the safety of trains. The application of deep learning algorithms was becoming an important method to realize its state detection. However, there was often a deficiency that the detection accuracy and calculation speed of model were difficult to balance, when the traditional deep learning model is used to detect the service state of track fasteners. Targeting this issue, an improved Yolov4 model for detecting the service status of track fasteners was proposed. Firstly, the Mixup data augmentation technology was introduced into Yolov4 model to enhance the generalization ability of model. Secondly, the MobileNet-V2 lightweight network was employed in lieu of the CSPDarknet53 network as the backbone, thereby reducing the number of algorithm parameters and improving the model’s computational efficiency. Finally, the SE attention mechanism was incorporated to boost the importance of rail fastener identification by emphasizing relevant image features, ensuring that the network’s focus was primarily on the fasteners being inspected. The algorithm achieved both high precision and high speed operation of the rail fastener service state detection, while realizing the lightweight of model. The experimental results revealed that, the MAP value of the rail fastener service state detection algorithm based on the improved Yolov4 model reaches 83.2%, which is 2.83% higher than that of the traditional Yolov4 model, and the calculation speed was improved by 67.39%. Compared with the traditional Yolov4 model, the proposed method achieved the collaborative optimization of detection accuracy and calculation speed.

关键词： Yolov4 Model Service Status of Track Fasteners Detection and Recognition Data Augmentation Lightweight Network Attention Mechanism

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基于排序码本的水声自适应OFDM通信中信道状态信息反馈研究

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电子与信息学报 2024年第5期46卷 2095-2103页

作者：刘凇佐韩雪马璐徐金颉杨洋哈尔滨工程大学水声技术全国重点实验室哈尔滨150001 工业和信息化部海洋信息获取与安全工信部重点实验室(哈尔滨工程大学) 哈尔滨150001 哈尔滨工程大学水声工程学院哈尔滨150001 哈尔滨工程大学三亚南海创新发展基地三亚572024

水声(UWA)信道时延扩展大等特点导致信道频响(CFR)快衰落,水声通信(UWAC)技术发展受到挑战。发射端获取有效可靠的信道状态信息(CSI)是自适应通信的前提,针对水声自适应正交频分复用(OFDM)通信的需求,该文提出基于排序码本的信道状态信... 详细信息

水声(UWA)信道时延扩展大等特点导致信道频响(CFR)快衰落,水声通信(UWAC)技术发展受到挑战。发射端获取有效可靠的信道状态信息(CSI)是自适应通信的前提,针对水声自适应正交频分复用(OFDM)通信的需求,该文提出基于排序码本的信道状态信息分组排序拟合反馈算法(CSI-GSFF),包括分组、排序、数据拟合3个步骤。该算法首先将相邻导频子载波分组,以组为反馈单元;然后对各组内的导频子载波按照信道增益值进行排序,以减轻水声信道频响快衰落造成的反馈开销大等不利影响;最后进行多项式拟合,排序操作有效地降低了拟合阶数。通过实测海试时变信道数据仿真,结果表明,该文提出的信道状态信息反馈算法能够基本达到完美信道状态信息情形下的水声自适应OFDM通信系统误码率性能,同时可以有效地减少反馈开销。

关键词：水声通信正交频分复用自适应调制信道状态信息有限反馈

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Review of Thermal Design of SiC Power Module for Motor Drive in Electrical Vehicle Application

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CES Transactions on Electrical Machines and Systems 2024年第3期 332-346页

作者： Puqi Ning Xiaoshuang Hui Dongrun Li Yuhui Kang Jiajun yang Chaohui Liu IEEE Key Laboratory of High Density Electromagnetic Power and Systems (Chinese Academy of Sciences) Institute of Electrical Engineering Chinese Academy of Sciences the school of Electronic Electrical and Communication Engineering University of Chinese Academy of Sciences the National New Energy Vehicle Technology Innovation Center

In the current vehicle electric propulsion systems, the thermal design of power modules heavily relies on empirical knowledge, making it challenging to effectively optimize irregularly arranged Pinfin structures, thereby limiting their performance. This paper aims to review the underlying mechanisms of how irregularly arranged Pinfins influence the thermal characteristics of power modules and introduce collaborative thermal design with DC bus capacitor and motor. Literature considers chip size, placement, coolant flow direction with the goal of reducing thermal resistance of power modules, minimizing chip junction temperature differentials, and optimizing Pinfin layouts. In the first step, algorithms should efficiently generating numerous unique irregular Pinfin layouts to enhance optimization quality. The second step is to efficiently evaluate Pinfin layouts. Simulation accuracy and speed should be ensured to improve computational efficiency. Finally, to improve overall heat dissipation effectiveness, papers establish models for capacitors, motors, to aid collaborative Pinfin optimization. These research outcomes will provide essential support for future developments in high power density motor drive for vehicles.

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