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Electrospun PCL/gelatin/arbutin nanofiber membranes as potent reactive oxygen species scavengers to accelerate cutaneous wound healing

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Regenerative Biomaterials 2024年第3期3卷 43-55页

作者： mindong Du Shuhan Liu Nihan Lan Ruiming Liang Shengde Liang Maoqiang Lan Disen Feng Li Zheng Qingjun Wei Ke Ma Department of Orthopaedics Trauma and Hand Surgery The First Affliated Hospital of Guangxi Medical UniversityGuangxi Medical UniversityNanning 530521China Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration The First Affliated Hospital of Guangxi Medical UniversityGuangxi Medicar UniversityNanning530021China Guangxi Collaborative Innovation Center for Biomedicine The First Affliated Hospital of Guangxi Medical UniversityGuangxi Medical UniversityNanning 530021China Department of Plastic&Cosmetic Surgery.The First Affliated Hospital of Guangxi Medical University Guangxi Medical UniversityNanning 530021China Pharmaceutical College Guangxi Medical UniversityNanning530021China

The presence of excessive reactive oxygen species(Ros)at a skin wound site is an important factor affecting wound *** scavenging,which regulates the ROS microenvironment,is essential for wound *** this study,we used novel electrospun PCL/gelatin/arbutin(PCL/G/A)nanofibrous membranes as wound dressings,with PCL/gelatin(PCL/G)as the backbone,and plantderived arbutin(hydroquinone-β-D-glucopyranoside,ARB)as an effective antioxidant that scavenges ROos and inhibits bacterial infection in *** loading of ARB increased the mechanical strength of the nanofibres,with a water vapour transmission rate of more than 2500g/(m^(2)×24h),and the water contact angle decreased,indicating that hydrophilicity and air permeability were significantly *** release and degradation experiments showed that the nanofibre membrane controlled the drug release and exhibited favourable *** experiments showed that the PCL/G/A nanofibre membranes were biocompatible,and DPPH and ABTS+radical scavenging experiments indicated that PCL/G/A could effectively scavenge ROS to reflect the antioxidant *** addition,haemostasis experiments showed that PCL/G/A had good haemostatic effects in vitro and in *** vivo animal wound closure and histological staining experiments demonstrated that PCL/G/A increased collagen deposition and remodelled epithelial tissue regeneration while showing good in vivo biocompatibility and *** conclusion,we successfully prepared a multifunctional wound dressing,PCL/G/A,for skin wound healing and investigated its potential role in wound healing,which is beneficial for the clinical translational application of phytomedicines.

关键词： arbutin nanofiber membranes wound dressing reactive oxygen species

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海洋工程深水浮式系统设计方法研究

南方能源建设 2015年第1期2卷 81-88页

作者：杨敏冬施凌中国能源建设集团广东省电力设计研究院有限公司广州510663 中交水运规划设计院有限公司北京100007

深水浮式系统主要由浮式平台、系泊系统和立管系统组成,浮式平台及其系泊缆索/立管的设计分析是平台系统正常作业和运行安全的重要保障。浮式平台的设计一般通过在频域内对平台进行水动力分析,然后将水动力荷载传递到有限元模型上对结... 详细信息

深水浮式系统主要由浮式平台、系泊系统和立管系统组成,浮式平台及其系泊缆索/立管的设计分析是平台系统正常作业和运行安全的重要保障。浮式平台的设计一般通过在频域内对平台进行水动力分析,然后将水动力荷载传递到有限元模型上对结构进行有限元分析。利用水动力分析结果和有限元分析结果,结合规范联合对平台进行设计。同时,由于浮式平台整体系统的非线性及动力学特性,势必要对浮式平台系统进行有效的时域耦合分析计算,整体耦合响应结果除了用于平台和系泊缆索/立管系统的初步设计外,还可作为系泊缆索或立管的动态边界条件,对其进行详细设计。针对这两种设计分析思路,首先对分析流程、分析中遇到的具体问题和研究方法进行简单介绍,然后结合软件应用,对海洋平台以及系泊缆索和立管的设计分析步骤进行总结介绍。

关键词：耦合分析水动力分析深水浮式平台系泊缆索有限元

40.5 kV及以下C-GIS真空断路器低温环境下机械操作性能的试验研究

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高压电器 2024年第8期60卷 275-281页

作者：高旻东杨士奇连进王其锦黄协平常州太平洋电力设备(集团)有限公司江苏常州213033 济南轨道交通集团有限公司济南250013 中铁建电气化局集团第一工程有限公司河南洛阳471013

40.5 kV及以下C-GIS真空断路器在低温工况下机械操作异常偶有发生,迫切需要提高低温时的机械操作可靠性。对真空断路器低温环境下机械操作性能的影响因素进行了深入分析,并通过试验的方法对低温下的机械操作性能进行了研究。试验结果表... 详细信息

40.5 kV及以下C-GIS真空断路器在低温工况下机械操作异常偶有发生,迫切需要提高低温时的机械操作可靠性。对真空断路器低温环境下机械操作性能的影响因素进行了深入分析,并通过试验的方法对低温下的机械操作性能进行了研究。试验结果表明:(1)润滑脂的粘性阻力是影响真空断路器在低温环境下操作异常的主要因素。(2)真空断路器传动链运动副选用低温润滑脂在正常环境温度以及低至-30℃时均可保证正常机械操作。真空断路器的传动链运动副优化及低温润滑脂选用提高了机械操作的稳定性和可靠性。

关键词：真空断路器低温机械操作传动链润滑脂

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海上风机支撑结构疲劳性能试验研究

南方能源建设 2020年第3期7卷 89-94页

作者：李恒军杨敏冬刘沙周德棕王大龙中国大唐集团海洋能源产业有限公司南海事业部汕头515000 中国能源建设集团广东省电力设计研究院有限公司广州510663 南方海上风电联合开发有限公司珠海519000

[目的]针对海上风机支撑结构的疲劳问题,进行了外加强环过渡段结构疲劳性能的试验研究。[方法]采用简化的支撑结构1/5缩尺模型进行了静力与疲劳试验,获得了模型的热点应力和疲劳寿命;并根据DNV的海上风机规范,采用不同类型单元对试验模... 详细信息

[目的]针对海上风机支撑结构的疲劳问题,进行了外加强环过渡段结构疲劳性能的试验研究。[方法]采用简化的支撑结构1/5缩尺模型进行了静力与疲劳试验,获得了模型的热点应力和疲劳寿命;并根据DNV的海上风机规范,采用不同类型单元对试验模型进行了有限元分析和疲劳寿命估算,将规范方法的计算结果与试验进行了比较。[结果]结果表明:试验结果和规范方法之间的差异主要源于S-N曲线的选取。[结论]最后根据试验数据,在DNV规范的基础上给出两种改进的疲劳校核方案,可为实际应用提供指导。

关键词：海上风电疲劳试验外加强环管节点支撑结构

MnCeTiO_(x)协同催化脱除氮氧化物与氯苯研究

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环境科学学报 2024年第3期44卷 345-353页

作者：汪振辉顾秋香杨波王刘莹雷玉杰黄琼陈敏东江苏省大气环境与装备技术协同创新中心江苏省大气环境监测与污染控制高技术研究重点实验室南京信息工程大学环境科学与工程学院南京210044

垃圾焚烧过程中会产生大量的氮氧化物(NO_(x))和含氯挥发性有机物(氯苯(CB)为代表).选择性催化还原(SCR)技术中脱硝催化剂可协同脱除氮氧化物与氯苯.而针对垃圾焚烧尾气,研究和开发可在除尘后布置的中低温(<250℃)协同脱除NO_(x)与CB的... 详细信息

垃圾焚烧过程中会产生大量的氮氧化物(NO_(x))和含氯挥发性有机物(氯苯(CB)为代表).选择性催化还原(SCR)技术中脱硝催化剂可协同脱除氮氧化物与氯苯.而针对垃圾焚烧尾气,研究和开发可在除尘后布置的中低温(<250℃)协同脱除NO_(x)与CB的催化剂对垃圾焚烧尾气污染物的控制至关重要.本文通过溶胶凝胶法制备一系列TiO_(x)掺杂的MnCeTiO_(x)催化剂,当Mn、Ce、Ti物质的量比为5∶1∶5时,5MnCe5TiO_(x)在160~220℃反应温度区间内,对NO_(x)的脱除效率≥95%,对氯苯的脱除效率≥90%.Ti的掺杂可促进MnCeO_(x)催化剂表面缺陷、表面吸附氧及微孔的生成,提高MnCeO_(x)催化剂氧化还原性能与表面活性Mn^(4+)的浓度.同时,反应机理研究表明,MnCeTiO_(x)协同脱除催化脱除NO_(x)与CB过程中,NH3与CB会产生竞争吸附;单齿复合亚硝酸、线性亚硝酸、桥接硝酸盐等是反应的主要中间体.

关键词：氮氧化物氯苯协同脱除 MnCeTiO_(x)

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仿水蛭蠕动爬行软体机器人设计

机器人 2024年第2期46卷 139-146页

作者：李恭新王民栋朱亚洲刘娜栾小丽刘飞江南大学物联网工程学院轻工过程先进控制教育部重点实验室江苏无锡214122 上海大学机电工程与自动化学院上海200444

为了寻求一种无损和对患者友好的肠道检查方法,提出并设计了一种仿水蛭的软体机器人。该仿水蛭软体机器人由2个以双层结构为“脚”的吸附驱动器和以自束缚多腔室为本体的伸缩驱动器组成,通过控制2个吸附驱动器的交替运动和伸缩驱动器的... 详细信息

为了寻求一种无损和对患者友好的肠道检查方法,提出并设计了一种仿水蛭的软体机器人。该仿水蛭软体机器人由2个以双层结构为“脚”的吸附驱动器和以自束缚多腔室为本体的伸缩驱动器组成,通过控制2个吸附驱动器的交替运动和伸缩驱动器的配合运动实现蠕动爬行。结合实际实验和数值仿真验证了吸附驱动器的吸附特性和伸缩驱动器的调节机理,并分别通过软体机器人在平面、斜坡和类肠道等环境的实验进一步验证了机器人的运动性能。吸附驱动器最大吸附力可达3.05N,软体机器人运动速度可达5mm/s,验证了该机器人可以在类肠道的环境中实现无损和可控的运行。这项工作有望为肠道疾病的检查和治疗应用提供无损和对患者友好的新方法。

关键词：软体机器人仿水蛭肠道检查

基于CAN总线的列车头尾端冗余测速测距系统

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城市轨道交通研究 2024年第9期27卷 236-241页

作者：何浩洋孟旭瑶吴敏东国睿科技股份有限公司南京211151

[目的]既有的列车测速测距技术大多经由ATP(列车自动防护)系统进行数据互联互通及交互,其实现过程较为复杂,且容易因时序问题造成列车定位失效,需要研究更为可靠、有效的技术方法,以实现列车的实时、精确定位。[方法]介绍了列车单端测... 详细信息

[目的]既有的列车测速测距技术大多经由ATP(列车自动防护)系统进行数据互联互通及交互,其实现过程较为复杂,且容易因时序问题造成列车定位失效,需要研究更为可靠、有效的技术方法,以实现列车的实时、精确定位。[方法]介绍了列车单端测速测距系统功能的实现流程,以及基于CAN(控制局域网)总线的列车头尾端冗余测速测距系统功能的实现流程,进一步对比了二者在数据处理流程上的不同。针对列车头尾端冗余测速测距系统,建立了列车运行速度计算模型及列车运行距离计算模型。在此基础上,考虑了列车车长及头尾端数据传输和处理过程存在延时等因素,进一步建立了列车运行速度校正模型及列车运行距离校正模型。搭建了列车运行仿真系统,用以模拟列车头端定位设备故障工况,分析该工况下列车头尾端冗余测速测距系统头尾端切换后数据的有效性。[结果及结论]在列车头端定位设备故障情况下,该系统可以持续输出有效的测速测距数据,准确描述列车的速度位置信息。

关键词：城市轨道交通列车列车定位技术控制局域网列车测速测距系统

Mn-Ce-Nb-O_x/P84 catalytic filters prepared by a novel method for simultaneous removal of particulates and NO

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Journal of Rare Earths 2019年第3期37卷 273-281页

作者： Bo yang Qiong Huang mindong Chen Yuesong Shen Shemin Zhu Jiangsu Collaborative Innovation Center of Atmospheric Environment and Equipment Technology (CICAEET) Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control School of Environmental Science and Engineering Nanjing University of Information Science & Technology Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) College of Materials Science and Engineering Nanjing Tech University

The Mn-Ce-Nb-O_x/P84 catalytic filter for removal of particulates and NO simultaneous was prepared by a novel method(foam coating method). The process parameters including the concentrations of PTFE emulsion, particle size of catalyst and calcination temperature for preparation of catalytic filters were analyzed. In addition, the physical properties and performance for removal of NO(NH_3-SCR) and particulates of Mn-Ce-Nb-O_x/P84 catalytic filter prepared under the optimized parameters, were also systematic studied. Results show that the process parameters had significant influences on stability and performance of catalytic filter, The Mn-Ce-Nb-O_x/P84 catalytic filter prepared by foam coating method under the optimized parameters, has satisfactory physical properties and catalytic performance for removal of NO and particulates at 140-220 ℃. The NO removal efficiency of catalytic filter can reach95.3% at 200 ℃ as the catalyst loading amount is 450 g/m^2, Moreover,the dust removal efficiency of MnGe-Nb-O_x/P84 catalytic filter reaches as high as 99.98%, and the PM2.5 removal efficiency also reaches99.98%. The anti-sulfur performance of Mn-Ce-Nb-O_x catalytic filter is also attractive, after injecting150 ppm SO_2, the NO removal efficiency still retains up to 85%. It is indicated that the foam coating method can not only make a bond of high strength between catalyst and filter, but also make the catalytic filter possessing an excellent and stable performance for removal of NO and particulates.

关键词： Foam coating method Simultaneous removal Mn-Ce-Nb-O_x/P84 catalytic filters NO Particulates Preparation method

Gravimetric analysis for PM_(2.5) mass concentration based on year-round monitoring at an urban site in Beijing

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Journal of Environmental Sciences 2016年第2期28卷 154-160页

作者： Yanli Wang Wen yang Bin Han Wenjie Zhang mindong Chen Zhipeng Bai State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental Sciences Collaborative Innovation Center of Atmospheric Environment and Equipment Technology Nanjing University of Information Science & Technology

Daily PM_（2.5）（particulate matter with an aerodynamic diameter of below 2.5 μm） mass concentrations were measured by gravimetric analysis in Chinese Research Academy of Environmental Sciences（CRAES）, in the northern part of the Beijing urban area, from December 2013 to April 2015. Two pairs of Teflon（T1/T2） and Quartz（Q1/Q2） samples were obtained, for a total number of 1352 valid filters. Results showed elevated pollution in Beijing,with an annual mean PM_（2.5）mass concentration of 102 μg/m^3. According to the calculated PM_（2.5）mass concentration, 50% of our sampling days were acceptable（PM_（2.5）〈 75 μg/m^3）, 30% had slight/medium pollution（75–150 μg/m^3）, and 7% had severe pollution（〉 250 μg/m^3）. Sampling interruption occurred frequently for the Teflon filter group（75%） in severe pollution periods,resulting in important data being missing. Further analysis showed that high PM_（2.5）combined with high relative humidity（RH） gave rise to the interruptions. The seasonal variation of PM_（2.5）was presented, with higher monthly average mass concentrations in winter（peak value in February, 422 μg/m^3）, and lower in summer（7 μg/m^3 in June）. From May to August, the typical summer period, least severe pollution events were observed, with high precipitation levels accelerating the process of wet deposition to remove PM_（2.5）. The case of February presented the most serious pollution, with monthly averaged PM_（2.5）of 181 μg/m^3 and 32% of days with severe pollution. The abundance of PM_（2.5）in winter could be related to increased coal consumption for heating needs.

关键词： PM_(2.5) Gravimetric analysis Sampling interruption Pollution level Relative humidity(RH) Seasonal variation