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Evidence for particle acceleration approaching PeV energies in the W51 complex

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science Bulletin 2024年第18期69卷 2833-2841页

作者： LHAASO Collaboration Zhen Cao F.Aharonian Axikegu Y.X.Bai Y.W.Bao D.Bastieri X.J.Bi Y.J.Bi W.Bian A.V.Bukevich Q.Cao W.Y.Cao Zhe Cao J.Chang J.F.Chang A.M.Chen E.S.Chen H.X.Chen Liang Chen Lin Chen Long Chen M.J.Chen M.L.Chen Q.H.Chen S.Chen S.H.Chen S.Z.Chen T.L.Chen Y.Chen N.Cheng Y.D.Cheng M.Y.Cui S.W.Cui X.H.Cui Y.D.Cui B.Z.Dai H.L.Dai Z.G.Dai Danzengluobu X.Q.Dong K.K.Duan J.H.Fan Y.Z.Fan J.Fang J.H.Fang K.Fang C.F.Feng H.Feng L.Feng S.H.Feng X.T.Feng Y.Feng Y.L.Feng S.Gabici B.Gao C.D.Gao Q.Gao W.Gao W.K.Gao M.M.Ge L.S.Geng G.Giacinti G.H.Gong Q.B.Gou M.H.Gu F.L.Guo X.L.Guo Y.Q.Guo Y.Y.Guo Y.A.Han M.Hasan H.H.He H.N.He J.Y.He Y.He Y.K.Hor B.W.Hou C.Hou X.Hou H.B.Hu Q.Hu S.C.Hu D.H.Huang T.Q.Huang W.J.Huang X.T.Huang X.Y.Huang Y.Huang X.L.Ji H.Y.Jia K.Jia K.Jiang X.W.Jiang Z.J.Jiang M.Jin M.M.Kang I.Karpikov D.Kuleshov K.Kurinov B.B.Li C.M.Li Cheng Li Cong Li D.Li F.Li H.B.Li H.C.Li Jian Li Jie Li K.Li S.D.Li W.L.Li W.L.Li X.R.Li Xin Li Y.Z.Li Zhe Li Zhuo Li E.W.Liang Y.F.Liang S.J.Lin B.Liu C.Liu D.Liu D.B.Liu H.Liu H.D.Liu J.Liu J.L.Liu M.Y.Liu R.Y.Liu S.M.Liu W.Liu Y.Liu Y.N.Liu Q.Luo Y.Luo H.K.Lv B.Q.Ma L.L.Ma X.H.Ma J.R.Mao Z.Min W.Mitthumsiri H.J.Mu Y.C.Nan A.Neronov L.J.Ou P.Pattarakijwanich Z.Y.Pei J.C.Qi M.Y.Qi B.Q.Qiao J.J.Qin A.Raza D.Ruffolo A.Sáiz M.Saeed D.Semikoz L.Shao O.Shchegolev X.D.Sheng F.W.Shu H.C.Song Yu.V.Stenkin V.Stepanov Y.Su D.X.sun Q.N.sun X.N.sun Z.B.sun J.Takata P.H.T.Tam Q.W.Tang R.Tang Z.B.Tang W.W.Tian C.Wang C.B.Wang G.W.Wang H.G.Wang H.H.Wang J.C.Wang Kai Wang Kai Wang L.P.Wang L.Y.Wang P.H.Wang R.Wang W.Wang X.G.Wang X.Y.Wang Y.Wang Y.D.Wang Y.J.Wang Z.H.Wang Z.X.Wang Zhen Wang Zheng Wang D.M.Wei J.J.Wei Y.J.Wei T.Wen C.Y.Wu H.R.Wu Q.W.Wu S.Wu X.F.Wu Y.S.Wu S.Q.Xi J.Xia G.M.Xiang D.X.Xiao G.Xiao Y.L.Xin Y.Xing D.R.Xiong Z.Xiong D.L.Xu R.F.Xu R.X.Xu W.L.Xu L.Xue D.H.Yan J.Z.Yan T.Yan C.W.yang C.Y.yang F.yang F.F.yang L.L.yang M.J.yang R.Z.yang W.X.yang Y.H.Yao Z.G.Yao L.Q.Yin N.Yin X.H.You Z.Y.You Y.H.Yu Q.Yuan H.Yue H.D.Zeng T.X.Zeng W.Zeng M.Zha B.B.Zhang F.Zhang H.Zhang 不详 Key Laboratory of Particle Astrophysics&Experimental Physics Division&computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China university of Chinese Academy of sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduChina Dublin Institute for Advanced Studies 31 Fitzwilliam Place2 DublinIreland Max-Planck-Institut for Nuclear Physics P.O.Box 103980Heidelberg 69029Germany school of Physical science and Technology&school of Information science and Technology Southwest Jiaotong UniversityChengdu 610031China school of Astronomy and Space science Nanjing UniversityNanjing 210023China Center for Astrophysics Guangzhou UniversityGuangzhou 510006China Tsung-Dao Lee Institute&school of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Institute for Nuclear Research of Russian Academy of sciences Moscow 117312Russia Hebei Normal university Shijiazhuang 050024China university of science and Technology of china Hefei 230026China State Key Laboratory of Particle Detection and Electronics China Key Laboratory of Dark Matter and Space Astronomy&Key Laboratory of Radio Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Research Center for Astronomical computing Zhejiang LaboratoryHangzhou 311121China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China school of Physics and Astronomy Yunnan UniversityKunming 650091China Key Laboratory of Cosmic Rays(Tibet university) Ministry of EducationLhasa 850000China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China school of Physics and Astronomy(Zhuhai)&school of Physics(guangzhou)&Sino-French Institute of Nuclear Engineering and Technology(Zhuhai) Sun Yat-sen UniversityZhuhai 519000&Guangzhou 510275GuangdongChina Institute of Frontier and Interdisciplinary science Shandong UniversityQingdao 266237China APC UniversitéParis Cité

Theγ-ray emission from the W51 complex is widely acknowledged to be attributed to the interaction between the cosmic rays(CRs)accelerated by the shock of supernova remnant(SNR)W51C and the dense molecular clouds in the adjacent star-forming region,***,the maximum acceleration capability of W51C for CRs remains *** on observations conducted with the Large High Altitude Air Shower Observatory(LHAASO),we report a significant detection ofγrays emanating from the W51 complex,with energies from 2 to 200 *** LHAASO measurements,for the first time,extend theγ-ray emission from the W51 complex beyond 100 TeV and reveal a significant spectrum bending at tens of *** combining the"π^(0)-decay bump"featured data from Fermi-LAT,the broadbandγ-ray spectrum of the W51 region can be well-characterized by a simple pp-collision *** observed spectral bending feature suggests an exponential cutoff at~400 TeV or a power-law break at~200 TeV in the CR proton spectrum,most likely providing the first evidence of SNRs serving as CR accelerators approaching the PeV ***,two young star clusters within W51B could also be theoretically viable to produce the most energeticγrays observed by *** findings strongly support the presence of extreme CR accelerators within the W51 complex and provide new insights into the origin of Galactic CRs.

关键词： UHE c-ray Cosmic rays SNR W51C Star clusters

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基于Abraham模型估算有机物表面张力

石油化工 2020年第11期49卷 1068-1075页

作者：左丽华陈六平东华理工大学化学生物与材料科学学院江西南昌330013 中山大学化学学院广东广州510275

根据线性溶剂化能量关系理论和经验方程,提出了在不同温度下估算纯有机物液体表面张力(σ)的关联式。利用所得关联式对2628个纯组分体系中的10个同系物进行了回归,得到了σ的关联方程,并对方程的相关性和外推适用性进行考察。实验结果表... 详细信息

根据线性溶剂化能量关系理论和经验方程,提出了在不同温度下估算纯有机物液体表面张力(σ)的关联式。利用所得关联式对2628个纯组分体系中的10个同系物进行了回归,得到了σ的关联方程,并对方程的相关性和外推适用性进行考察。实验结果表明,8个关联方程中各参数与σ的相关系数都达良好级以上,平均相对偏差均低于5%,方程适用性良好,并具有良好的普适性,可为纯有机物σ的计算提供一种可靠的方法。

关键词：线性溶剂化能量关系表面张力分子参数估算

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基于Abraham模型估算有机物蒸发焓

石油化工 2020年第2期49卷 145-152页

作者：左丽华陈六平东华理工大学化学生物与材料科学学院江西南昌330013 中山大学化学学院广东广州510275

根据线性自由溶剂化能关系理论和经验方程,提出了在不同温度下,估算纯有机物液体蒸发焓的关联式,利用所得关系式对1105个纯组分体系中的8个同系物进行了回归,得到了蒸发焓的关联方程,对方程的相关性和外推适用性进行考察。实验结果表明,... 详细信息

根据线性自由溶剂化能关系理论和经验方程,提出了在不同温度下,估算纯有机物液体蒸发焓的关联式,利用所得关系式对1105个纯组分体系中的8个同系物进行了回归,得到了蒸发焓的关联方程,对方程的相关性和外推适用性进行考察。实验结果表明,8个关联方程中各参数与蒸发焓的相关系数都达良好级以上,平均相对偏差值均低于5%,方程适用性良好,且在其他温度下对蒸发焓的预测效果也较好,具有良好的普适性。该方程形式简单,估算精度高,适用范围广,成功地将物质的宏观物理性质与分子微观结构结合起来,为纯有机物蒸发焓的计算提供了一种可供选择的方法。

关键词：线性溶剂化能量关系蒸发焓分子参数估算

In Situ Formation of Frustrated Lewis Pairs in a Zirconium Metal-Organic Cage for Sustainable CO_(2)Chemical Fixation

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CCS Chemistry 2023年第9期5卷 1989-1998页

作者： Cheng-Xia Chen Hassan Rabaâ Haiping Wang Pui Ching Lan yang-yang Xiong Zhang-Wen Wei Abdullah M.Al-Enizi Ayman Nafady Shengqian Ma Department of Chemistry University of North TexasDentonTexas 76201 MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional MaterialsSchool of ChemistrySun Yat-sen UniversityGuangzhou 510275 Department of Chemistry Ibn Tofail UniversityESCTM14000 Kenitra Department of Chemistry College of ScienceKing Saud UniversityRiyadh 11451

Sustainable CO_(2)fixation represents a facile and promising approach to constructing various valueadded ***,we contribute a robust metal-organic cage(MOC),denoted as TCPB-1,comprising a bulky Lewis acid functionalized linker,which can in situ form frustrated Lewis pairs(FLPs)upon the addition of Lewis basic substrates to efficiently drive CO_(2)***,the incorporation of Lewis acidic boron sites within TCPB-1 promotes the efficient CO_(2)conversion to potentially medicinal benzimidazole derivatives via an FLPmediated pathway,and boosts the stability/durability of the FLP *** addition,the underlying catalysis mechanism has been established by combined experimental and molecular simulation *** work not only advances FLP/MOC as a new type of highly efficient catalyst for CO_(2)chemical fixation,but also opens a new avenue to design heterogeneous FLP-based catalysts for small molecule activation and beyond.

关键词： metal-organic cage frustrated Lewis pair heterogeneous catalysis CO_(2)conversion sustainable chemistry

Discrete Time-Varying Four Fundamental Operations Implemented by Euler Forward Difference

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Discrete Time-Varying Four Fundamental Operations Implemente...

第36届中国控制会议

作者： Yunong Zhang Huihui Gong Jian Li Binbin Qiu Min yang school of Information science and Technology Sun Yat-sen University Key Laboratory of Autonomous Systems and Networked Control Ministry of Education

ISBN: (纸本)9781538629185

Time-varying problems are widely encountered in various engineering fields,such as signal processing,construction monitoring,and ***,traditional arithmetics intrinsically aim at time-invariant problems *** running on relatively low-speed processing units,traditional arithmetics may generate quite large and unacceptable lagging *** this paper,the problems of discrete time-varying four fundamental operations(TVFFO) are *** order to eliminate the lagging errors,based on Zhang dynamics(ZD) and Euler forward difference(EFD) formula,discrete computing models,which are named Euler-implemented discrete ZD(EIDZD) models,are proposed and *** that the EIDZD models are with an error pattern 0(g),where g denotes the sampling ***,illustrative numerical experiments of EIDZD models are also conducted,which show the high accuracy of EIDZD models.

关键词： Time-varying four fundamental operations(TVFFO) Zhang dynamics(ZD) Continuous time-varying models Euler forward difference(EFD) Euler-implemented discrete ZD(EIDZD) models Numerical experiments

来源： cnki会议评论

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热电耦合作用下功率器件引脚开裂的机理

科学通报 2020年第20期65卷 2169-2177页

作者：高丽茵李财富曹丽华刘志权中国科学院深圳先进技术研究院深圳先进电子材料国际创新研究院深圳518055 中国科学院金属研究所沈阳110016 中山大学材料学院广州510275

在电子产品的小型化的趋势下,电力电子器件所承受的工作温度、电流密度越来越高,这给封装材料提出了严峻的挑战.一种引线框架材料为C194合金的MOSFET器件,在高电流密度的工作环境下服役3~4年后发生了引脚开裂的现象.针对该失效现象,使... 详细信息

在电子产品的小型化的趋势下,电力电子器件所承受的工作温度、电流密度越来越高,这给封装材料提出了严峻的挑战.一种引线框架材料为C194合金的MOSFET器件,在高电流密度的工作环境下服役3~4年后发生了引脚开裂的现象.针对该失效现象,使用扫描电子显微镜对界面金属间化合物和断口形貌进行了精细的微观表征,确定了电迁移和热迁移的耦合作用是导致引脚开裂的主要原因.具体地,对于器件源极来说,Cu原子的电迁移与热迁移方向相反,且热迁移扩散通量较大,抵消了电迁移的作用从而导致了阳极开裂的反常现象.对于器件漏极来说,Cu原子的热迁移方向与电迁移方向相同,热迁移加速了阴极界面裂纹的萌生与扩展,开裂情况最为严重.为了进一步揭示开裂机理,我们使用电子探针、透射电子显微镜分析发现,在C194合金与金属间化合物界面上,原本弥散分布于C194合金内部的铁晶粒发生了明显的晶粒长大,并富集形成连续层.由于细小铁晶粒组成的富铁层弱化原有的界面结合力,成为薄弱环节.因此,在外加热应力或机械应力下,裂纹总是沿着由铁晶粒形成的富铁层发生开裂.综上,该器件引脚开裂的失效模式为典型的多场耦合作用下的失效形式,相关机理将为产品工艺优化和提高使用寿命提供理论指导.

关键词： C194合金引脚开裂热迁移电迁移失效分析

Imputing DNA Methylation by Transferred Learning Based Neural Network

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Journal of Computer science & Technology 2022年第2期37卷 320-329页

作者： Xin-Feng Wang Xiang Zhou Jia-Hua Rao Zhu-Jin Zhang Yue-Dong yang school of Computer science and Engineering Sun Yat-sen UniversityGuangzhou 510000China Key Laboratory of Machine Intelligence and Advanced computing of Ministry of Education(sun yat-sen university)guangzhou 510000 China

DNA methylation is one important epigenetic type to play a vital role in many diseases including *** the development of the high-throughput sequencing technology,there is much progress to disclose the relations of DNA methylation with ***,the analyses of DNA methylation data are challenging due to the missing values caused by the limitations of current *** many methods have been developed to impute the missing values,these methods are mostly based on the correlations between individual samples,and thus are limited for the abnormal samples in *** this study,we present a novel transfer learning based neural network to impute missing DNA methylation data,namely the TDimpute-DNAmeth *** method learns common relations between DNA methylation from pan-cancer samples,and then fine-tunes the learned relations over each specific cancer type for imputing the missing *** on 16 cancer datasets,our method was shown to outperform other commonly-used *** analyses indicated that DNA methylation is related to cancer survival and thus can be used as a biomarker of cancer prognosis.

关键词： neural network transfer learning DNA methylation data imputation survival analysis

面向GPU的非结构网格有限体积计算流体力学的图染色方法优化

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国防科技大学学报 2022年第5期44卷 24-34页

作者：张曦孙旭郭晓虎杜云飞卢宇彤刘杨中山大学计算机学院(软件学院) 广东广州510006 哈璀国家超算中心达斯伯里实验室英国沃林顿WA44AD 中国空气动力研究与发展中心四川绵阳621000

采用图染色方法解决通量累加和局部最大压力计算引起的两种典型资源竞争问题,并通过共享内存的使用、体编号和面编号的重排、面数据的重排三种策略优化图染色方法。针对应用在空气动力学多种规模的三维网格,分别采用双精度和单精度操作... 详细信息

采用图染色方法解决通量累加和局部最大压力计算引起的两种典型资源竞争问题,并通过共享内存的使用、体编号和面编号的重排、面数据的重排三种策略优化图染色方法。针对应用在空气动力学多种规模的三维网格,分别采用双精度和单精度操作数,在Nvidia Tesla V100和K80 GPU上,展开性能测试。结果表明:共享内存的优化效果不明显;体编号和面编号重排降低了图染色方法的计算性能;面数据重排可以有效地优化图染色方法;计算性能在V100上提高20%左右,在K80上提高15%左右。

关键词：非结构网格有限体积图形处理器资源竞争图染色

Hidden Genetic Regulation of Human Complex Traits via Brain Isoforms

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Phenomics 2023年第3期3卷 217-227页

作者： Lu Pan Chenqing Zheng Zhijian yang Yudi Pawitan Trung Nghia Vu Xia Shen Biostatistics Group School of Life SciencesSun Yat-Sen UniversityGuangzhou 510006China Department of Medical Epidemiology and Biostatistics Karolinska InstitutetStockholm 17177Sweden State Key Laboratory of Genetic Engineering School of Life SciencesFudan UniversityShanghai 200433China Center for Intelligent Medicine Research Greater Bay Area Institute of Precision Medicine(Guangzhou)Fudan UniversityGuangzhou 511458China Centre for Global Health Research Usher InstituteUniversity of EdinburghEdinburgh EH89AGUK

Alternative splicing exists in most multi-exonic genes,and exploring these complex alternative splicing events and their resultant isoform expressions is ***,it has become conventional that RNA sequencing results have often been summarized into gene-level expression counts mainly due to the multiple ambiguous mapping of reads at highly similar ***-level quantification and interpretation are often overlooked,and biological interpretations are often deduced based on combined transcript information at the gene ***,for the most variable tissue of alternative splicing,the brain,we estimate isoform expressions in 1,191 samples collected by the Genotype-Tissue Expression(GTEx)Consortium using a powerful method that we previously *** perform genome-wide association scans on the isoform ratios per gene and identify isoform-ratio quantitative trait loci(irQTL),which could not be detected by studying gene-level expressions *** analyzing the genetic architecture of the irQTL,we show that isoform ratios regulate edu-cational attainment via multiple tissues including the frontal cortex(BA9),cortex,cervical spinal cord,and *** tissues are also associated with different neuro-related traits,including Alzheimer’s or dementia,mood swings,sleep duration,alcohol intake,intelligence,anxiety or depression,*** randomization(MR)analysis revealed 1,139 pairs of isoforms and neuro-related traits with plausible causal relationships,showing much stronger causal effects than on general diseases measured in the UK Biobank(UKB).Our results highlight essential transcript-level biomarkers in the human brain for neuro-related complex traits and diseases,which could be missed by merely investigating overall gene expressions.

关键词： Alternative splicing Isoform-ratio quantitative trait loci(irQTL) Expression quantitative trait loci(eQTL) Genome-wide Association Studies Neuro-related human complex traits