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A Localization Method of High Energy Transients for All-sky Gamma-ray Monitor

research in Astronomy and Astrophysics 2024年第10期24卷 25-35页

作者： Yi Zhao Wangchen Xue Shaolin Xiong Qi luo Yuanhao Wang Jiacong Liu Heng Yu Xiaoyun Zhao Yue Huang Jinyuan Liao Jianchao Sun Xiaobo Li Qibin Yi Ce Cai Shuo Xiao Shenglun Xie Chao Zheng Yanqiu Zhang chenwei Wang {2. Tan Zhiwei Guo Chaoyang Li Zhenghua An gang chen Yanqi du Min Gao Ke Gong Dongya Guo Jiang He Jianjian He Bing Li gang Li Xinqiao Li Jing Liang Xiaohua Liang Yaqing Liu Xiang Ma Rui Qiao Liming Song Xinying Song Xilei Sun Jin Wang Ping Wang Xiangyang Wen Hong Wu Yanbing Xu Sheng yang Dali Zhang Fan Zhang Hongmei Zhang Peng Zhang Shu Zhang Zhen Zhang Shijie Zheng Keke Zhang Xingbo Han Haiyan Wu Hu Tai Hao Geng Gaopeng lu Wei Xu Fanchao Lyu Hongbo Zhang Fangjun lu Shuangnan Zhang Department of Astronomy Beijing Normal UniversityBeijing 100875China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China School of Physics and Optoelectronics Xiangtan UniversityXiangtan 411105China College of Physics Hebei Normal UniversityShijiazhuang 050024China Guizhou Provincial Key Laboratory of Radio Astronomy and Data Processing Guizhou Normal UniversityGuiyang 550001China School of Physics and Electronic Science Guizhou Normal UniversityGuiyang 550001China Institute of Astrophysics Central China Normal UniversityWuhan 430079China College of physics Sciences Technology Hebei UniversityBaoding 071002China Physics and Space Science College China West Normal UniversityNanchong 637002China School of Computing and Artificial Intelligence Southwest Jiaotong UniversityChengdu 611756China College of Electronic and information Engineering Tongji UniversityShanghai 201804China Innovation Academy for Microsatellites of Chinese Academy of Sciences Shanghai 201304China national Space Science center Chinese Academy of SciencesBeijing 100190China School of Earth and Space Sciences University of Science and Technology of ChinaHefei 230026China Electronic Information School Wuhan UniversityWuhan 430072China Key Laboratory of Transportation Meteorology of china Meteorological Administration Nanjing Joint Institute for Atmospheric SciencesNanjing 210000China Key Laboratory of Middle Atmosphere and Global Environment Observation Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China

Fast and reliable localization of high-energy transients is crucial for characterizing the burst properties and guiding the follow-up *** based on the relative counts of different detectors has been widely used for all-sky gamma-ray *** are two major methods for this count distribution localization:χ^(2.minimization method and the Bayesian *** we propose a modified Bayesian method that could take advantage of both the accuracy of the Bayesian method and the simplicity of the χ^(2.*** comprehensive simulations,we find that our Bayesian method with Poisson likelihood is generally more applicable for various bursts than the χ^(2.method,especially for weak *** further proposed a location-spectrum iteration approach based on the Bayesian inference,which could alleviate the problems caused by the spectral difference between the burst and location *** method is very suitable for scenarios with limited computation resources or timesensitive applications,such as in-flight localization software,and low-latency localization for rapidly follow-up observations.

关键词： methods:data analysis methods:analytical (stars:)gamma-ray burst:general

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Distribution of Traditional Chinese Medicine syndromes in diabetic kidney disease chronic kidney disease 1-5: a correlation study

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Journal of Traditional Chinese Medicine 2024年第3期44卷 572-580页

作者： LI Shuang duAN Shuwei DONG Zheyi qu Yilun luO Yayong KE Jianghua WANG Conghui PENG yangzhi ZHOU Xuefeng chen Xiangmei Department of Nephrology First Medical Center of Chinese PLA General HospitalNephrology Institute of the Chinese People's Liberation ArmyNational Key Laboratory of Kidney DiseasesNational Clinical Research Center for Kidney DiseasesBeijing Key Laboratory of Kidney Disease ResearchBeijing 100853China School of Clinical Medicine Guangdong Pharmaceutical Universityjuangzhou510006China Basic Medical College Chengdu University of Traditional Chinese MedicineChengdu610075China

OBJECTIVE: To analyze the distribution of Traditional Chinese medicine(TCM) syndromes in patients with diabetic kidney disease(DKD) and its related ***: We enrolled 43. patients with DKD, who were not undergoing dialysis, admitted to the Department of Nephrology, First Medical center, Chinese PLA General Hospital from April 2.2. to August *** of their TCM syndromes and related factors was carried ***: The 43. patients inc{3.ded 109, 117, 86, and 12. chronic kidney disease(CKD) 1-2. CKD3. CKD4, and CKD5 cases, respectively. With the progression of CKD1-5, the proportion of Yin deficiency and dry heat syndrome,and that of Qi and Yin deficiency syndrome showed a downward trend, whereas the proportion of spleen-kidney yang deficiency, blood deficiency, blood stasis, water stagnation, and phlegm turbidity syndromes showed an upward trend;the differences were statistically significant(P 2., P = 0.005], albumin(OR = 1.058, P = 0.006), and estimated glomerular filtration rate(eGFR)(OR = 1.02.,P 2.7, P = 0.004). Qi and Yin deficiency syndrome was positively correlated with albumin(OR = 1.056, P 2.) but negatively correlated with age(OR = 0.977, P = 0.02.). Liver-kidney Yin deficiency syndrome was positively correlated with age(OR = 1.02., P = 0.02.) and glycosylated hemoglobin(OR = 1.2.3. P = 0.007) but negatively correlated with total cholesterol(OR = 0.792. P = 0.006).Spleen-kidney yang deficiency syndrome was negatively correlated with hemoglobin(OR = 0.977, P 3.3.6, P = 0.001). CONC{3.SION: With CKD1-5 progression, TCM syndromes changed from Yin deficiency and dry

关键词： diabetic nephropathies syndrome and complex hemoglobins albumins glomerular filtration rate correlation of data

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Multiomics analysis reveals metabolic subtypes and identifies diacylglycerol kinase α (DGKA) as a potential therapeutic target for intrahepatic cholangiocarcinoma

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Cancer Communications 2024年第2期44卷 226-250页

作者： Weiren Liu Huqiang Wang Qianfu Zhao chenyang Tao Weifeng qu Yushan Hou Run Huang Zimei Sun Guiqi Zhu Xifei Jiang Yuan Fang Jun Gao Xiaoling Wu Zhixiang yang Rongyu Ping Jiafeng chen Rui yang Tianhao Chu Jian Zhou Jia Fan Zheng Tang Dong yang Yinghong Shi Department of Liver Surgery and Transplantation Liver Cancer InstituteZhongshan HospitalFudan UniversityKey Laboratory of Carcinogenesis and Cancer Invasion of Ministry of EducationShanghaiP.R.China research Unit of Liver cancer Recurrence and Metastasis Chinese Academy of Medical SciencesBeijingP.R.China State Key Laboratory of Medical Proteomics Beijing Proteome Research CenterNational Center for Protein Sciences(Beijing)Beijing Institute of LifeomicsBeijingP.R.China

Background:Intrahepatic cholangiocarcinoma(iCCA)is a highly heteroge-neous and lethal hepatobiliary tumor with few therapeutic *** metabolic reprogramming of tumor cells plays an essential role in the develop-ment of tumors,while the metabolic molecular classification of iCCA is largely ***,we performed an integrated multiomics analysis and metabolic classification to depict differences in metabolic characteristics of iCCA patients,hoping to provide a novel perspective to understand and treat ***:We performed integrated multiomics analysis in 116 iCCA samples,including whole-exome sequencing,bulk RNA-sequencing and proteome *** on the non-negative matrix factorization method and the protein abundance of metabolic genes in human genome-scale metabolic models,the metabolic subtype of iCCA was *** and prognostic gene analy-ses were used to compare overall survival(OS)differences between metabolic *** proliferation analysis,5-ethynyl-{3.-deoxyuridine(Edu)assay,colony formation assay,RNA-sequencing and Western blotting were performed to investigate the molecular mechanisms of diacylglycerol kinaseα(DGKA)in iCCA ***:Three metabolic subtypes(S1-S3.with subtype-specific biomarkers of iCCA were *** metabolic subtypes presented with distinct prog-noses,metabolic features,immune microenvironments,and genetic *** S{3.subtype with the worst survival showed the activation of some special metabolic processes,immune-suppressed microenvironment and Kirsten ratsar-coma viral oncogene homolog(KRAS)/AT-rich interactive domain 1A(ARID1A)*** the S{3.subtype-specific upregulated proteins,DGKA was further identified as a potential drug target for iCCA,which promoted cell proliferation by enhancing phosphatidic acid(PA)metabolism and activating mitogen-activated protein kinase(MAPK)***:Viamultiomics analyses,we identified three metabolic subtypes of iCCA,revealing

关键词： diacylglycerol kinaseα intrahepatic cholangiocarcinoma MAPK signaling metabolic classifi-cation multiomics analysis phosphatidic acid metabolism

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Mapping the Characteristics of Respiratory Infectious Disease Epidemics in china Based on the Baidu Index from November 2.2. to January 2.2.

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china CDC weekly 2024年第37期6卷 939-945,I0001-I0007页

作者： Dazhu Huo Ting Zhang Xuan Han Liuyang yang Lei Wang Ziliang Fan Xiaoli Wang Jiao yang Qiangru Huang Ge Zhang Ye Wang Jie Qian Yanxia Sun Yimin {3. Yugang Li Chuchu Ye luzhao Feng Zhongjie Li Weizhong yang chen Wang School of Health Policy and Management Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijingChina School of Population Medicine and Public Health Chinese Academy of Medical Sciences(CAMS)&Peking Union Medical CollegeBeijingChina Yichang center for Disease Prevention and Control Yichang CityHubei ProvinceChina Weifang center for Disease Prevention and Control Weifang CityShandong ProvinceChina beijing center for Disease Prevention and Control BeijingChina School of Public Health Dali UniversityDali CityYunnan ProvinceChina Shanghai Pudong New Area center for Disease Control and Prevention ShanghaiChina

Introduction:Infectious diseases pose a significant global health and economic burden,underscoring the critical need for precise predictive *** Baidu index provides enhanced real-time surveillance capabilities that augment traditional ***:Baidu search engine data on the keyword“fever”were extracted from {3.5 cities in china from November {3.{3. to January *** and peak dates for influenza epidemics were identified by testing various criteria that combined thresholds and consecutive ***:The most effective scenario for indicating epidemic commencement involved a 90th percentile threshold exceeded for seven consecutive days,minimizing false *** detection was optimized using a 7-day moving average,balancing stability and ***:The use of internet search data,such as the Baidu index,significantly improves the timeliness and accuracy of disease surveillance *** innovative approach supports faster public health interventions and demonstrates its potential for enhancing epidemic monitoring and response efforts.

关键词： faster precise false

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A Blood Hepatocellular Carcinoma Signature Recognizes Very Small Tumor Nodules with Metastatic Traits

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Journal of Clinical and Translational Hepatology 2024年第6期12卷 551-561页

作者： Kun chen Junxiao Wang Liping Jiang Fei Zhao Ruochan Zhang Zhiyuan Wu Dongmei Wang Yuchen Jiao Hui Xie Chunfeng qu State Key Lab of Molecular Oncology Department of ImmunologyNational Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Senior Department of Oncology Fifth Medical Center of Chinese PLA General HospitalBeijingChina Aerospace Medical center/Aerospace center Hospital Peking University Aerospace Clinical CollegeBeijingChina State Key Lab of Molecular Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Background and Aims:Hepatocellular carcinoma(HCC)cases with small nodules are commonly treated with radi-ofrequency ablation(RFA),but the recurrence rate remains *** study aimed to establish a blood signature for identifying HCC with metastatic traits ***:Data from HCC patients treated between {3.0 and {3.7 were retrospectively collected.A blood signature for meta-static HCC was established based on blood levels of alpha-fetoprotein and des-γ-carboxy-prothrombin,cell-free DNA(cfDNA)mutations,and methylation changes in target genes in frozen-stored plasma samples that were collected before RFA *** HCC blood signature was validated in patients prospectively enrolled ***:Of {3. HCC patients in the retrospective study,3..9% experienced recurrence within 1 year *** HCC blood signature identified from these patients included des-γ-carboxy-prothrombin≥40mAU/mL with cfDNA mutation score,where cfDNA mutations occurred in the genes of TP53.CTNNB1,and TERT *** signature effectively predicted 1-year post-RFArecurrence of HCC with 92. specificity and 91% sensitivity in the retrospective dataset,and with 87% specificity and 76% sensitivity in the prospective dataset(n=3.7}patients).Among 14 cases in the prospective study with biopsy tissues available,positivity for the HCC blood signature was associated with a higher HCC tissue score and shorter distance between HCC cells and ***:This study established an HCC blood signature in pre-RFA blood that potentially reflects HCC with metastatic traits and may be valuable for predicting the disease’s early recurrence post-RFA.

关键词： Liquid biopsy Liver dysplastic nodules Radiofrequency ablation Hepatocellular carcinoma Recurrence prediction Metastatic nodules

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Mineralization episode of porphyry copper deposits in the Jinshajiang-Red River mineralization belt: Re-Os dating

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Science china Earth Sciences 2005年第2期48卷 192-198页

Re-Os isotopic dating for the molybdenites from the porphyry copper deposits of the Jinshajiang-Red River mineralization belt in Yunnan Province yields isochron ages of 3..9±1.1 Ma for the Machangqing deposit and 3..4±0.5 Ma for the Tongchang deposit. This result shows that both the Machangqing and the Tongchang porphyry Cu-Mo deposits from two different ore-fields formed simultaneously. This new data and the published Re-Os model ages of molybdenite (3..4 Ma, 3..9 Ma, 3..2.Ma) of the Yulong porphyry copper deposit in Tibet, which is located in the same Jinshajiang-Red River mineralization belt as the Machangqing deposit and the Tongchang deposit, suggest that these three Cenozoic porphyry copper deposits in the Jinshajiang-Red River mineralization belt were contemporary for their mineralization episode. That is to say, even their present locality is far away and nearly iso-distantly distributed, these three porphyry Cu(Mo) deposits belong to the same mineralization episode at the end of Eocene.

关键词： Re-Os isotopic dating, porphyry Cu deposits, Cenozoic, mineralization episode.

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The associations between the environmental exposure to polychlorinated biphenyls (PCBs) and breast cancer risk and progression

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Science china Chemistry 2010年第5期53卷 974-979页

作者： LIU SiJin ,ZHANG ShuPing,qu chen,LIU Wei & du YuGuo State Key Laboratory of Environmental Chemistry and Ecotoxicology {3. {2. for Eco-Environmental Sciences,Chinese Academy of Sciences,beijing 100085,china State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Beijing China

Polychlorinated biphenyls(PCBs) are chlorinated biphenyl compounds with wide applications in the *** spite of a ban on their production in the late 1970s,PCBs,as a group of POPs,are still persistent and widely spread in the environment,posing potential threats to human *** role of PCBs as etiologic agents for breast cancer has been intensively explored in a variety of in vivo,animal and epidemiologic *** investigations indicated higher levels of PCBs in mammary tissues or sera corresponded to the occurrence of breast cancer,but later studies showed no positive association between PCB exposure and breast cancer *** recent data suggested that the CYP1A1 m2.polymorphisms might add increased risk to the etiology of breast cancer in women with environmental exposure to *** are implicated in advancing breast cancer progression,and our unpublished data reveals that PCBs activate the ROCK signaling to enhance breast cancer ***,the correlation between PCB exposure and breast cancer risk warrants further careful investigations.

关键词： Polychlorinated biphenyls (PCBs) environmental exposure CYP1A1 polymorphisms breast cancer risk tumor progression

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Isotopic Chronological Study of the Huangsha-Tieshanlong quartz Vein-Type Tungsten Deposit and Timescale of Molybdenum Mineralization in Southern Jiangxi Province,china

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Acta geologica Sinica(English Edition) 2011年第6期85卷 1434-1447页

作者： HUANG Fan FENG chengyou chen Yuchuan YING Lijuan chen Zhenghui1 ZENG Zailin {3. wenjun Key Laboratory of Metallogeny and Mineral Resource Assessment Institute of Mineral Resources Chinese Academy of Geological Sciences Beijing 100037 China Chinese Academy of geological Sciences Beijing 100037 China geological Survey Team of South Jiangxi Ganzhou Jiangxi 341000 China national research {2. of{3.analysis Beijing 100037 China

The Huangsha-Tieshanlong quartz-vein tungsten polymetallic ore deposit, located in the northern Pangushan-Tieshanlong tungsten ore field in eastern Ganxian-Yudu prospecting areas of the Yushan metallogenic belt, is a well-known tungsten deposit in southern Jiangxi province, china. SHRIMP-determined dating of zircons from the Tieshanlong granite yields ages of 168.1±{3. Ma （n=11, MSWD-1.3.. Rhenium and osmium isotopic dating of molybdenite from the Huangsha quartz-vein tungsten deposit determined by ICP-MS yields a weighted average ages of 153.3.Ma and model ages of 150.2.1} Ma - 155.4-2.3.Ma. The age of the Huangsha tungsten deposit is 10 to 15 Ma later than the Tieshanlong granite, which shows that there might have been another early Late Jurassic magmatic activity between 150 and 160 Ma, a process which is closely related with tungsten mineralization in this area. The Tieshanlong granite, the Hnangsha tungsten deposit and the Pangushan-Tieshanlong ore field were all formed around 150-170 Ma, belonging to products of a Mesozoic second large-scale mineralization. According to the collected molybdenite Re-Os dating results in southern Jiangxi province, the timescale of the associated molybdenum mineralization is 2.6 Ma in the tungsten deposit and the timescale of independent molybdenum mineralization is 1-4 Ma, implying the complexity of tungsten mineralization. Times of molybdenum mineralization are mainly concentrated in the Yanshanian, which includes three stages of 13.-13. Ma, 150-162.Ma, and 166-170 Ma, respectively. The 150-162.Ma-stage is in accordance with ages of large-scale WoSn mineralization, which is mainly molybdenum mineralization characterized by associated molybdenum mineralization with development of an even greater-intensity independent molybdenum mineralization. Independent molybdenum mineralization occurred before and after large-scale W-Sn mineralization, which indicates that favorable prospecting period for molybdenum may be in Cretaceous and e

关键词： SHRIMP zircon U-Pb molybdenite Re-Os ages timescale granite quartz vein-type tungsten deposit Huangsha Tieshanlong Jiangxi

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geodynamic Background of Intracontinental Cenozoic Alkaline Volcanic Rocks in Laojiezi, Western yangtze Craton: Constraints from Sr-Nd-Hf-O Isotopes

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Acta geologica Sinica(English Edition) 2018年第6期92卷 2098-2119页

作者： YAN Qinggao JIANG Xiaojun LI Chao ZHOU Limin WANG Zhongqiang Sultan Baig SHER qu wenjun du {3. Department of Earth Sciences Faculty of Land Resource EngineeringKunming University of Science and Technology beijing SHRIMP center Chinese Academy of Geological Sciences national research {2. for {3.analysis Chinese Academy of Geological Sciences Department of Earth Science Karakoram International University

The Laojiezi alkaline volcanic rocks, which are located in the intraplate region of the yangtze craton, coincide with the formation of the Jinshajiang-Ailaoshan-Red River alkaline rock belt. Although this belt has been widely studied by geologists because of its porphyry-related Pb-Ag-Au polymetallic deposit and geotectonic location, the material sources of this belt are still debate. Whole-rock analyses show that these rocks have high total alkali contents(3.73.11.08 wt%), and their a{3.minum saturation index(ASI) va{3.es widely vary from 0.82.to 3.07, which comprise a meta{3.minous-pera{3.minous magma series. These rocks are characterized by high K(K2.O/Na2.O>1) and low Ti and Mg contents; enrichment in large-ion lithophile elements, such as Rb, Ba, K and light rare earth elements; and depletion in high field strength elements, such as Ta, Nb, P, and Ti. These rocks exhibit moderate Eu(Eu/Eu*=0.86–1.04) and Ce(Ce/Ce*=0.63.0.96) anomalies. Their(87 Sr/86 Sr)i, εNd(t), zircon εHf(t) and δ18 O va{3.es range from 0.7083. to 0.71013. from-10.16 to-12.45, from-19.6 to-5.8, and from 5.69‰ to 8.54‰, respectively, and their Nd and Hf two-stage model ages(TDM2. are 1.67–1.86 Ga and 1.2.–2.02.Ga, respectively. These data reflect the primary partial melting of Paleoproterozoic to Mesoproterozoic lower crust with minor residual continental lithospheric mantle and supracrustal metasediments. The lithosphere was likely thickened along the southeastern margin of the Tibetan Plateau following the Indian-Asian continentcontinent collision(65–41 Ma). during the post-collision phase(3.–16 Ma), the transition from a compressional to extensional setting triggered the convective removal of the over-thickened CLM beneath the yangtze craton, which led to the upwelling of asthenospheric materials. This process created alkali-rich and high-K magma through the partial melting of the thickened lower crust. Magma that carried Cu-Au-Pb-Ag minerals was emplaced by strike-slip motion along the E-to W-

关键词： Sr-Nd-Hf-O isotopes alkaline volcanic rocks post-collision Laojiezi deposit western yangtze craton

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Re-Os geochronology of Cu and W-Mo deposits in the Balkhash metallogenic belt,Kazakhstan and its geological significance

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geoscience Frontiers 2010年第1期1卷 115-124页

作者： Xuanhua chen wenjun qu Shuqin Han Seitmuratova Eleonora Nong {{3. Zhengle chen Fagang Zeng andao du Zhihong Wang Key Laboratory of Neotectonic Movement ＆ geohazard Ministry of Land and Resources Beijing 100081 PR China Institute of geomechanics Chinese Academy of Geological Sciences 11 Minzudaxue Nan Road-Beijing 100081 PR China national research {2. for {3.analysis Beijing 100037 PR China Laboratory of geological Formations K. Satpaev Institute of Geological Sciences Almaty 050010 Kazakhstan

The Central Asian metallogenic domain （CAMD） is a multi-core metallogenic system controlled by boundary strike-slip fault systems. The Balkhash metallogenic belt in Kazakhstan, in which occur many large and super-large porphyritic Cu--Mo deposits and some quartz vein- and greisen-type W-Mo deposits, is a well-known porphyritic Cu--Mo metallogenic belt in the CAMD. In this paper 11 molybdenite samples from the western segment of the Balkhash metallogenic belt are selected for Re--Os compositional analyses and Re--Os isotopic dating. Molybdenites from the Borly porphyry Cu deposit and the three quartz vein-greisen W--Mo deposits--East Kounrad, Akshatau and Zhanet--all have relatively high Re contents （2.1{3.-{3.7{3.μg/g for Borly and {3.{3.7--3..50 μg/g for the other three W-Mo deposits）, and lower common Os contents （0.670-{3.696 ng/g for Borly and 0.0051--0.056 ng/g for the other three）. The molybdenites from the Borly porphyry Cu--Mo deposit and the East Kounrad, Zhanet, and Akshatau quartz vein- and greisen-type W-Mo deposits give average model Re--Os ages of 3.5.9 Ma, {3.8.0 Ma, {3.5.0 Ma, and {3.9.3.Ma respectively. Meanwhile, molybde- nites from the East Kounrad, Zhanet, and Akshatan W-Mo deposits give a Re--Os isochron age of {3.7.9 Ma, with an MSWD value of 0.97. Re--Os dating of the molybdenites indicates that Cu-W-Mo metallogenesis in the western Balkhash metallogeuic belt occurred during Late Carboniferous to Early Permian （3.5.9--{3.9.3.Ma）, while the porphyry Cu--Mo deposits formed at ~3.6 Ma, and the quartz vein-greisen W--Mo deposits formed at ~{3.8 Ma. The Re--Os model and isochron ages thus suggest that Late Carboniferous porphyry granitoid and pegmatite magmatism took place during the late Hercy- nian movement. Compared to the Junggar-East Tianshan porphyry Cu metallogenic belt in northwestern china, the formation of the Cu-Mo metallogenesis in the Balkhash rnetallogenic belt occurred between that of the Tuwu-Yandong in East Tianshan and the Baogutu porphyry Cu

关键词： Re-Os geochronology Metallogenic age Porphyry Cu-Mo deposit Greisen W--Mo deposits Balkhash metallogenicbelt Kazakhstan

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