检索结果-南通市图书馆

Uncovering hidden nodes and hidden links in complex dynamic networks

在线全文

学校读者我要写书评

暂无评论

Science china(Physics,Mechanics & Astronomy) 2024年第4期67卷 51-63页

作者： Zhaoyang Zhang Xinyu Wang Haihong Li yang {2. Zhilin {3. Yuanyuan Mi gang Hu Department of Physics School of Physical Science and TechnologyNingbo UniversityNingbo 315211China School of Science Beijing University of Posts and TelecommunicationsBeijing 100876China Department of Medicine David Geffen School of MedicineUniversity of CaliforniaLos Angeles 90095USA Brainnetome center and national Laboratory of Pattern Recognition Institute of AutomationChinese Academy of SciencesBeijing 100190China Department of Psychology Tsinghua UniversityBeijing 100084China Department of Physics Beijing Normal UniversityBeijing 100875China

Inferring network structures from available data has attracted much interest in network science;however,in many realistic networks,only some of the nodes are perceptible while others are hidden,making it a challenging *** this work,we develop a method for reconstructing the network with hidden nodes and links,taking account of fast-varying noise and time-delay *** calculating the correlations of available data with different derivative orders for multiple pairs of accessible nodes,analyzing and integrating the relationships between different correlations,and defining diverse hidden-node-related reconstruction motifs,we can effectively identify the hidden nodes and hidden links in the network.

关键词： networks and genealogical trees stochastic analysis methods time series analysis

Safety,immunogenicity and protective effect of sequential vaccination with inactivated and recombinant protein COVID-19 vaccine in the elderly:a prospective longitudinal study

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2024年第6期9卷 2738-2747页

作者： Hong-Hong Liu Yunbo Xie Bao-Peng yang Huan-Yue Wen Peng-Hui yang Jin-E lu Yan Liu Xi {{3. Meng-Meng qu yang Zhang Wei-Guo Hong Yong-gang Li Junliang Fu Fu-Sheng Wang Out-patient Department of Day Diagnosis and Treatment The Fifth Medical Center of Chinese PLA General HospitalBeijing 100039China Senior Department of Infectious Diseases The Fifth Medical Center of Chinese PLA General HospitalNational Clinical Research Center for Infectious DiseasesBeijing 100039China Chinese PLA Medical School Chinese PLA General HospitalBeijing 100039China Hunyuan County People’s Hospital Datong 037499 Shanxi ProvinceChina Faculty of Hepato-Pancreato-Biliary Surgery Institute of Hepatobiliary SurgeryThe First Medical CenterChinese PLA General HospitalBeijing 100853China

The safety and efficacy of COVID-19 vaccines in the elderly,a high-risk group for severe COVID-19 infection,have not been fully *** clarify these issues,this prospective study followed up 157 elderly and 73.young participants for 16 months and compared the safety,immunogenicity,and efficacy of two doses of the inactivated vaccine BBIBP-CorV followed by a booster dose of the recombinant protein vaccine *** results showed that this vaccination protocol was safe and tolerable in the *** administering two doses of the BBIBP-CorV,the positivity rates and titers of neutralizing and anti-RBD antibodies in the elderly were significantly lower than those in the young *** the ZF2.01 booster dose,the antibody-positive rates in the elderly were comparable to those in the young;however,the antibody titers remained ***,age,and underlying diseases were independently associated with vaccine immunogenicity in elderly *** pseudovirus neutralization assay showed that,compared with those after receiving two doses of BBIBP-CorV priming,some participants obtained immunological protection against BA.5 and BF.7 after receiving the ZF2.01 *** infection symptoms last longer in the infected elderly and pre-infection antibody titers were negatively associated with the severity of post-infection *** antibody levels in the elderly increased significantly after breakthrough infection but were still lower than those in the *** data suggest that multiple booster vaccinations at short intervals to maintain high antibody levels may be an effective strategy for protecting the elderly against COVID-19.

关键词： vaccination vaccine doses

Highly sensitive flexible strain sensor based on the two-dimensional semiconductor tellurium with a negative gauge factor

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science china(Information Sciences) 2024年第7期67卷 295-304页

作者： Jiarui HE Yusong qu Shengyao chen Cong WANG Lena du Xiaoshan du Yuanyuan ZHENG Guozhong ZHAO He TIAN College of Mathematics and Physics Beijing University of Chemical Technology School of Integrated Circuits Tsinghua University Beijing China & The Beijing National Research Center for Information Science and Technology (BNRist)Tsinghua University CAS center for Excellence in Nanoscience National Center for Nanoscience and Technology &University of Chinese Academy of Sciences beijing Key Lab of Terahertz Spectroscopy and Imaging Key Lab of Terahertz OptoelectronicsMinistry of Education Department of Physics Capital Normal University

research on flexible strain sensors has advanced rapidly in recent years, with particular attention being devoted to two-dimensional(2.) semiconductor materials owing to their exceptional mechanical and electrical properties that are conducive to sophisticated sensing performance. However, resistive strain sensors based on 2. semiconductor materials typically exhibit positive gauge factors(GF), while materials for strain sensors with a negative GF remain elusive. We have identified a trend of reduction in the band gap of the emerging 2. semiconductor material tellurium(Te) under strain in simulations reported in past research,and have observed a negative GF in the Te-based strain sensor. In this study, we combined Te with a flexible polyethylene terephthalate(PET) substrate to manufacture a flexible strain sensor with a significantly negative GF. The results of tests revealed that the Te-based strain sensor achieved an impressive maximum sensitivity of-13..7 within a small range of bending-induced strain(< 1%). Furthermore, it exhibited excellent linearity and good cyclic stability, and was successfully applied to monitor limb movements. The work here verifies the significant potential for the use of Te-based strain sensors in next-generation flexible electronics.

关键词： 2. semiconductor materials 2. tellurium flexibleelectronics strain sensors negative gauge factor high sensitivity

Synergistic improvement of strength and ductility via doping cerium into PH13.8Mo stainless steel by laser powder b e d fusion

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2024年第7期174卷 106-119页

作者： Chang Liu Jianxiong Liang Changjun Wang gang chen Xuanhui qu Yu Liu Zhenbao Liu Mengxing Zhang Central Iron&Steel research Institute Company Limited Beijing 100081China beijing Advanced Innovation center for Materials Genome Engineering Institute for Advanced Materials and TechnologyUniversity of Science and Technology BeijingBeijing 100083China

In this study,the PH13.8Mo stainless steel parts doped without and with cerium(Ce)were fabricated via laser powder bed fusion followed by post-heat treatment,and systematically compared in terms of microstructure,phase constituent,and tensile *** comparative results show that doping Ce-modified grains with the equiaxed morphology and finer size,increased the mechanical stability of austenite,and enhanced the sphericity of oxide inclusion in the resultant ***,the coherency between the newly-formed CeAlO 3.inclusion and matrix was effectively im proved after doping Ce,as compared to the original aluminum oxide inclusion without doping *** resultant PH13.8Mo parts doped with Ce yielded an ultimate tensile strength of 1446±2. MPa with a fracture elongation of 16.0%±1.5%,for the first time meeting the AMS 562.E H1000 standard for the PH13.8Mo made by additive manufacturing(AM).The enhanced strength results from the strengthening effects of nanoscale precipitation(inclusion)and grain ***,the ductilizing mechanism can be attributed to the enhanced inclusion sphericity and ameliorative coherency between the inclusion and matrix,and improved misorientation angle of grain boundary owing to the modification by Ce,which efficiently re-duced the stress concentration and enhanced cracking resistance during ***,doping rare earth elements presents a promising pathway to synergistically improve the strength and ductility of stainless steels by AM.

关键词： Stainless steel Additive manufacturing Rare earth Precipitation Tensile properties

Anisotropic magnetism and band evolution induced by ferromagnetic phase transition in titanium-based kagome ferromagnet SmTi_3.i_4

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science china(Physics,Mechanics & Astronomy) 2024年第6期67卷 137-145页

作者： Zhe Zheng Long chen Xuecong Ji Ying Zhou Gexing qu Mingzhe Hu Yaobo Huang Hongming Weng Tian Qian gang Wang beijing national Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China School of Physics and Engineering Henan University of Science and TechnologyLuoyang 471023China Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201210China Songshan Lake Materials Laboratory Dongguan 523808China CAS center for Excellence in Topological quantum Computation Chinese Academy of SciencesBeijing 100190China

Kagome magnets with diverse topological quantum responses are crucial for next-generation topological *** anisotropic magnetism and band evolution induced by ferromagnetic phase transition(FMPT)is reported in a newly discovered titanium-based kagome ferromagnet Sm Ti3.i4,which features a distorted Ti kagome lattice and Sm atomic zig-zag ***-dependent resistivity,heat capacity,and magnetic susceptibility reveal a ferromagnetic ordering temperature Tc of{3..{3.K.A large magnetic anisotropy,observed by applying the magnetic field along three crystallographic axes,identifies the b axis as the easy ***-resolved photoemission spectroscopy with first-principles calculations unveils the characteristic kagome motif,including the Dirac point at the Fermi level and multiple van Hove ***,a band splitting and gap closing attributed to FMPT is observed,originating from the exchange coupling between Sm 4 f local moments and itinerant electrons of the kagome Ti atoms,as well as the time-reversal symmetry breaking induced by the long-range ferromagnetic *** the large in-plane magnetization and the evolution of electronic structure under the influence of ferromagnetic ordering,such materials promise to be a new platform for exploring the intricate electronic properties and magnetic phases based on the kagome lattice.

关键词： kagome lattice anisotropic magnetism band splitting ferromagnetic phase transition ARPES

Re-Os dating of gold-bearing arsenopyrite of the Maoling gold deposit,Liaoning Province,Northeast china and its geological significance

在线全文

学校读者我要写书评

暂无评论

Chinese Science Bulletin 2005年第14期50卷 1509-1514页

作者： YU gang yang gang {3. jiangfeng qu wenjun du andao HE Wei Laboratory of Crust-Mantle Materials and Environments School of Earth and Space Sciences University of Science and Technology of China Hefei 230026 China national research {2. of {3.analysis Chinese Academy of Geological Sciences Beijing 100037 China 5th geological Survey Party Liaoning Province Dashiqiao 115100 China

The Maoling gold deposit, one of the large gold deposits in eastern Liaoning Province, NE china, is an ar- senopyrite-disseminated gold deposit with a resource of ap- proximately 2. t Au and an average Au grade of 3.2.g/t. Six arsenopyrites closely related to Au mineralization of the Maoling gold deposit are dated by Re-Os techni{3.e and de- fine a Re-Os isochron with an age of 2.16±140 Ma, which suggests that the deposit was formed in the Paleoproterozoic era rather than in the Indosinian period as some early re- searchers suggested. High initial 187Os/188Os ratio of 1.3.1}0.48 indicates a crustal derivation of the ore-forming material of the deposit, which may be derived from rocks of the Gaixian formation of the Liaohe Group. Furthermore, the result also implies that the age of the Gaixian Formation in the Maoling district is older than 2.16±140 Ma.

关键词：中国辽宁地质学黄金沉积黄铁矿

Aging hallmarks of the primate ovary revealed by spatiotemporal transcriptomics

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Protein & Cell 2024年第5期15卷 364-384页

作者： Huifen lu Ying Jing chen Zhang Shuai Ma Weiqi Zhang Daoyuan Huang Bin Zhang Yuesheng Zuo Yingying Qin Guang-Hui Liu yang Yu Jing {3. Si Wang Advanced Innovation center for Human Brain Protection National Clinical Research Center for Geriatric DisordersXuanwu Hospital Capital Medical UniversityBeijing 100053China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Aging Translational Medicine center International Center for Aging and CancerBeijing Municipal Geriatric Medical Research CenterXuanwu HospitalCapital Medical UniversityBeijing 100053China State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China beijing Institute for Stem Cell and Regenerative Medicine Beijing 100101China CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of SciencesBeijing 100101China Institute for Stem cell and Regeneration CASBeijing 100101China china national {2. for Bioinformation Beijing 100101China The Fifth People’s Hospital of Chongqing Chongqing 400062China Sino-Danish College University of Chinese Academy of SciencesBeijing 101408China Sino-Danish center for Education and research Beijing 101408China Department of Obstetrics and Gynecology Center for Reproductive MedicinePeking UniversityThird HospitalBeijing 100191China Clinical Stem Cell research center Peking UniversityThird HospitalBeijing 100191China center for Reproductive Medicine Cheeloo College of MedicineShandong UniversityJinan 250012China Key Laboratory of Reproductive Endocrinology of Ministry of Education National Research Center for Assisted Reproductive Technology and Reproductive GeneticsShandong Key Laboratory of Reproductive MedicineShandong Provincial Clinical Research Center for Reproductive HealthJinan 250012China Key Laboratory of Organ Regeneration and Reconstruction Institute of ZoologyChinese Academy of SciencesBeijing 100101China Aging Biomarker Consortium Beijing 100101China

The ovary is indispensable for female reproduction,and its age-dependent functional decline is the primary cause of ***,the molecular basis of ovarian aging in higher vertebrates remains poorly ***,we apply spatiotemporal transcriptomics to benchmark architecture organization as well as cellular and molecular determinants in young primate ovaries and compare these to aged primate *** a global view,somatic cells within the non-follicle region undergo more pronounced transcriptional fluctuation relative to those in the follicle region,likely constituting a hostile microenvironment that facilitates ovarian ***,we uncovered that inflammation,the senescent-associated secretory phenotype,senescence,and fibrosis are the likely primary contributors to ovarian aging(PCOA).Of note,we identified spatial co-localization between a PCOA-featured spot and an unappreciated MT{3.Metallothionein {3.highly expressing spot(MT{3.(high))characterized by high levels of inflammation,potentially serving as an aging hotspot in the primate ***,with advanced age,a subpopulation of MT{3.(high)accumulates,likely disseminating and amplifying the senescent signal *** study establishes the first primate spatiotemporal transcriptomic atlas,advancing our understanding of mechanistic determinants underpinning primate ovarian aging and unraveling potential biomarkers and therapeutic targets for aging and age-associated human ovarian disorders.

关键词： spatial transcriptome primate ovary aging senescence inflammation

Expression and functional analysis of the rice plasma-membrane intrinsic protein gene family

在线全文

学校读者我要写书评

暂无评论

Cell research 2006年第3期16卷 277-286页

作者： Lei Guo~1 Zi Yi Wang~1 Hong Lin~1 Wei Er Cui~1 Jun chen~1 Meihua Liu~1 Zhang Liang chen~(1,2. Li Jia {3.~(1,2. Hongya Gu~(1,{2. Peking-Yale Joint research center for Plant Molecular Genetics and AgroBiotechnology,national Laboratoryfor Protein Engineering and Plant Genetic Engineering,College of Life Sciences,Peking University,beijing 100871,china 2.The national Plant Gene research center,beijing 100101,china Peking-Yale Joint research center for Plant Molecular Genetics and AgroBiotechnology National Laboratory for Protein Engineering and Plant Genetic Engineering College of Life Sciences Peking University Beijing China The national Plant Gene research {2. Beijing China

Plasma membrane intrinsic proteins (PIPs) are a subfamily of aquaporins that enable fast and controlled translocationof water across the *** this study,we systematically identified and cloned ten PIP genes from *** on thesimilarity of the amino acid sequences they encoded,these rice PIP genes were classified into two groups and designatedas OsPIPI-1 to OsPIP1-3.and OsPIP2.1 to OsPIP{3.7 following the nomenclature of PIP genes in ***-PCR analysis identified three root-specific and one leaf-specific OsPIP ***,the expression profile ofeach OsPIP gene in response to salt,drought and ABA treatment was examined in *** on transgenic plantsover-expressing of either OsPIP1 (OsPIPI-1) or OsPIP{3.(OsPIP{3.{3. in wild-type Arabidopsis,showed enhanced toler-ance to salt (100 mM of NaCl) and drought ({3.0 mM of mannitol),but not to salt treatment of higher concentration (150mM of NaCl).Taken together,these data suggest a distinct role of each OsPIP gene in response to different stresses,andshould add a new layer to the understanding of the physiological function of rice PIP genes.

关键词： aquaporins PIP quantitative RT-PCR Oryza sativa organ-specific

Arabidopsis AtBECLIN 1/AtAtg6/AtVps3. is essential for pollen germination and plant development

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Cell research 2007年第3期17卷 249-263页

作者： Genji Qin~1 Zhiqiang Ma~1 Li Zhang~1 Shufan Xing~1 Xianhui Hou~1 Jie Deng~1 Jingjing Liu~1 Zhangliang chen~(1,2. Li-Jia qu~(1,2. Hongya Gu~(1,2. ~1national Laboratory for Protein Engineering and Plant Genetic Engineering,Peking- Yale Joint {2. center for Plant Molecular Genetics and AgroBiotechnology,College of Life Sciences,Peking University,beijing 100871,china ~2.he national Plant Gene {2. center (beijing),beijing 100101,china national Laboratory for Protein Engineering and Plant Genetic Engineering Peking-Yale Joint Research Center for Plant Molecular Genetics and AgroBiotechnology College of Life Sciences Peking University Beijing 100871 China The national Plant Gene research {2. ({3.) Beijing 100101 China

Pollen germination on the surtace ot compatible stigmatic tissues is an essential step tor plant *** wereport that the Arabidopsis mutant bcl1 is male sterile as a result of the failure of pollen *** show that the bcl1mutant allele cannot be transmitted by male gametophytes and no homozygous bcl1 mutants were *** ofpollen developmental stages indicates that the bcl1 mutation affects pollen germination but not pollen ***-lar analysis demonstrates that the failure of pollen germination was caused by the disruption of AtBECLIN ***1 is expressed predominantly in mature pollen and encodes a protein with significant homology to Beclin1/Atg6/Vps3.required for the processes of autophagy and vacuolar protein sorting(VPS)in *** also show that AtBECLIN 1 isrequired for normal plant development,and that genes related to autophagy,VPS and the glycosylphosphatidylinositolanchor system,were affected by the deficiency of AtBECLIN 1.

关键词： Arabidopsis thaliana AtBECLIN 1 pollen germination plant normal development