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Microstructure and Mechanical Properties of AZ91D Magnesium Alloy Recycled from Scraps by Hot-press/extrusion

Journal of Harbin Institute of Technology(New Series) 2014年第1期21卷 115-120页

作者： Mao-Liang Hu Ze-Sheng Ji Xiao-Yu chen qu-Dong Wang School of Materials Science and Engineering Harbin University of Science and Technology national Engineering research {2. for Light Alloy Net Forming Shanghai Jiao Tong University

A large number of scraps are produced in the fabrication process of magnesium alloy products. It is necessary to recycle these scraps for the development and scale application of magnesium alloys. In this research,a method for recycling AZ91D magnesium alloy scraps fabricated by hot-press / extrusion was studied. Mechanical properties and microstructure of the recycled specimens were investigated. Microstructural analyses were performed by using the techniques of optical microscopy and scanning electron microscopy. Microstructural observations reveal that the recycled specimens consisted of fine grains when adopting the extrusion temperature of 400- 450 ℃,the extrusion ratio of( 2.- 100) ∶ 1 and the extrusion rate of 0. 10- 0. 2. mm / s. Ultimate tensile strength and elongation to failure increased with the increase of the extrusion temperature,the extrusion ratio and the extrusion rate,respectively. Recycled specimens reached the highest ultimate tensile strength of average 361. 47 MPa and the highest elongation to failure of average 11. 55% when adopting the hot-press,the extrusion temperature of 400± 5 ℃,the extrusion ratio of 100 ∶ 1 and the extrusion rate of 0. 15 mm / s. The shape of bonding interface was tightly relation with the ultimate tensile strength. When the bonding interface formed continuous curves,the ultimate tensile strength decreased almost linearly with increasing the average width of the bonding interface. When the bonding interface formed discontinuous curves,the ultimate tensile strength increased almost linearly with the increase the proportion of the fine bonding length accounting for the measured interface length. Ultimate tensile strength of the recycled specimens could be calculated by using the forecastable equation.

关键词： scraps magnesium alloy mechanical property bonding interface

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QTL analysis of leaf photosynthesis rate and related physiological traits in Brassica napus

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Journal of Integrative Agriculture 2015年第7期14卷 1261-1268页

作者： YAN Xing-ying qu Cun-min LI Jia-na chen Li LIU Lie-zhao College of Agronomy and Biotechnology Southwest University Biotechnology research center Southwest University

Rapeseed （Brassica napus L.） oil is the crucial source of edible oil in China. In addition, it can become a major renewable and sustainable feedstock for biodiesel production in the future. It is known that photosynthesis products are the primary sources for dry matter accumulation in rapeseed. Therefore, increasing the photosynthetic efficiency is desirable for the raise of rapeseed yield. The objective of the present study was to identify the genetic mechanism of photosynthesis based on the description of relationships between different photosynthetic traits and their quantitative trait loci （QTL） by using a recombinant inbred line （RIL） population with 172.lines. Specifically, correlation analysis in this study showed that internal CO2.concentration has negative correlations with other three physiological traits under two different stages. Totally, 11 and 12.QTLs of the four physiological traits measured at the stages 1 and 2.were detected by using a high-density single nu- cleotidepolymorphism （SNP） markers linkage map with composite interval mapping （CIM）, respectively. Three co-localized QTLs on A03 were detected at stage 1 with 5, 5, and 10% of the phenotypic variation, respectively. Other two co-localized QTLs were located on A05 at stage 2. which explained up to 12.and 5% of the phenotypic variation, respectively. The results are beneficial for our understanding of genetic control of photosynthetic physiological characterizations and improvement of rapeseed yield in the future.

关键词： Brassica napus photosynthesis quantitative trait loci (QTL)

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A three-dimensional hollow graphene fiber microelectrode with shrink-effect-enabled enzyme immobilization for sensor applications

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Science Bulletin 2019年第11期64卷 718-722页

作者： Liwei chen Xiaoteng Ding Jinfeng Zeng Lejiao Chongbei Wu Yuze Wang Qing Han Liangti qu Key Laboratory of Photoelectronic/Electrophotonic Conversion Materials Key Laboratory of Cluster ScienceMinistry of Education of ChinaSchool of Chemistry and Chemical EngineeringBeijing Institute of TechnologyBeijing 100081China College of Life Sciences. Qingdao University Qingdao 266071China

Microelectrodes are a type of electrode with microscopic dimension, and due to their rapid diffusing rates, high electrical current densities and signal-to-noise ratios, they can help improve the detection sensitivity for various analytes [1]. Investigations on the fabrication and the application of microelectrodes are highly relevant. Fiber-type microelectrodes with one-dimensional (ID) microstructures that possess ID diffusion, particularly carbon fiber microelectrodes, have been widely fabricated and used in many different types of sensors due to their low cost, small volume, portability, and good biocompatibility [1,2.. However, poor electrocatalytic activity and low response currents preclude the applications of carbon fiber microelectrodes in sensors.

关键词： Microelectrodes three-dimensional hollow sensor applications

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Dopaminergic neurons show increased low-molecular-mass protein 7 activity induced by 6-hydroxydopamine in vitro and in vivo

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Translational Neurodegeneration 2018年第1期7卷 175-186页

作者： Ming-Shu Mo Gui-Hua Li Cong-Cong Sun Shu-Xuan Huang Lei Wei Li-Min Zhang Miao-Miao Zhou Zhuo-Hua Wu Wen-Yuan Guo Xin-Ling yang Chao-Jun chen Shao-{2. qu Jian-Xing He Ping-Yi Xu Department of Neurology First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510120GuangdongChina Department of Neurology Qilu Hospital of Shandong UniversityJinan 250012ShandongChina Department of Neurology First Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510080GuangdongChina Department of Neurology Second Affiliated Hospital of Xinjiang Medical UniversityUrumchi 830011XinjiangChina Clinic Brain center Guangzhou Hospital of Integrated Traditional and Western MedicineGuangzhou 510800GuangdongChina Department of Blood Transfusion Fifth Affiliated Hospital Southern Medical UniversityGuangzhou 510900GuangdongChina Department of Thoracic Surgery First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510120Guangdong China

Background:Abnormal expression of major histocompatibility complex class I(MHC-I)is increased in dopaminergic(DA)neurons in the substantia nigra(SN)in Parkinson’s disease(PD).Low-molecular-mass protein 7(β5i)is a proteolytic subunit of the immunoproteasome that regulates protein degradation and the MHC pathway in immune ***:In this study,we investigated the role of β5i in DA neurons using a 6-hydroxydopamine(6-OHDA)model in vitro and ***:We showed that 6-OHDA upregulatedβ5i expression in DA neurons in a concentration-and time-dependent *** and downregulation ofβ5i induced the expression of glucose-regulated protein(Bip)and exacerbated 6-OHDA neurotoxicity in DA *** inhibition of β5i further promoted the activation of Caspase 3-related pathways induced by 6-OHDA.β5i also activated transporter associated with antigen processing 1(TAP1)and promoted MHC-I expression on DA ***:Taken together,our data suggest that β5i is activated in DA neurons under 6-OHDA treatment and may play a neuroprotective role in PD.

关键词： Parkinson’s disease 6-hydroxydopamine Immunoproteasome TAP1

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Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome

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Protein & Cell 2018年第4期9卷 333-350页

作者： Zeming Wu Weiqi Zhang Moshi Song Wei Wang gang Wei Wei Li Jinghui Lei Yu Huang Yanmei Sang Piu Chan Chang chen Jing qu Keiichiro Suzuki Juan Carlos Izpisua Belmonte Guang-Hui Liu State Key Laboratory of Stem Cell and Reproductive Biology Institute of Zoology Chinese Academy of Sciences Beijing 100101 China national Laboratory of Biomacromolecules CAS Center for Excellence in Biomacromolecules Institute of Biophysics Chinese Academy of Sciences Beijing 100101 China University of Chinese Academy of Sciences Beijing 100049 China national Clinical research {2. for Geriatric Disorders Xuanwu Hospital of Capital Medical University Beijing 100053 China State Key Laboratory of Biomembrane and Membrane Biotechnology Institute of Zoology Chinese Academy of SciencesBeijing 100101 China Key Laboratory of Computational Biology CAS-MPG Partner Institute for Computational Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai 200031 China Department of Medical genetics School of Basic Medical Sciences Peking University Health Science Center Beijing100191 China Department of Pediatric Endocrinology and Genetic Metabolism Beijing Children's Hospital Capital Medical UniversityNational Center for Children's Health Beijing 100045 China Institute for Advanced Co-Creation Studies Osaka University Osaka 560-8531 Japan Graduate School of Engineering Science Osaka University Osaka 560-8531 Japan Gene Expression Laboratory Salk Institute for Biological Studies La Jolla 92037 USA Key Laboratory of Regenerative Medicine of Minist~ of Education Institute of Aging and Regenerative Medicine JinanUniversity Guangzhou 510632 China

progeria syndrome （HGPS） and Wemer syndrome （WS） are two of the best characterized human progeroid syndromes. HGPS is caused by a point mutation in lamin A （LMNA） gene, resulting in the production of a truncated protein product-progerin. WS is caused by mutations in 14/RN gem）, encoding a loss-of-function RecQ DNA helicase. Here, by gene editing we created isogenic human embryonic stem cells （ESCs） with heterozygous （G608G/＋） or homozygous （G608G/G608G） LMNA mutation and biallelic WRN knockout, for modeling HGPS and WS pathogenesis, respectively. While ESCs and endothelial cells （ECs） did not present any features of premature senescence, HGPS- and WS-mesenchymal stem cells （MSCs） showed aging-associated phenotypes with different kinetics. WS-MSCs had early-onset mild premature aging phenotypes while HGPS-MSCs exhibited iate-onset acute premature aging characterisitcs. Taken together, our study compares and contrasts the distinct pathologies underpinning the two premature aging disorders, and provides reliable stem-cell based models to identify new therapeutic strategies for pathological and physiological aging.

关键词： WRN lamin HGPS Werner syndrome,stem cell aging

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基于Sentinel-2.据的山仔水库水华遥感监测

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亚热带资源与环境学报 2024年第3期19卷 179-188页

作者：陈若薇陈峰陈增文屈同翁笑艳陈文惠金致凡雷少华福建师范大学地理科学学院、碳中和未来技术学院福州350117 福建师范大学地理研究所福州350117 福建省环境监测中心站福州350003 福建省福州环境监测中心站福州350011 南京水利科学研究院水灾害防御全国重点实验室南京210029 北京水保生态工程咨询有限公司北京100055

山仔水库位于福建省福州市连江县,利用Sentinel-2.分辨率多光谱遥感影像,结合多种水体提取算法和藻类水华识别方法,对山仔水库2.19—2.2.年间的水华进行了时空分析。研究结果表明:1)在水体提取方面,NDWI在研究区域内表现最佳,能够有效... 详细信息

山仔水库位于福建省福州市连江县,利用Sentinel-2.分辨率多光谱遥感影像,结合多种水体提取算法和藻类水华识别方法,对山仔水库2.19—2.2.年间的水华进行了时空分析。研究结果表明:1)在水体提取方面,NDWI在研究区域内表现最佳,能够有效识别水体边界。2.在水华反演方面,通过NDVI和FAI的阈值法以及随机森林(RF)、支持向量机(SVM)、梯度提升树(GBT)等监督分类方法的对比分析,结果显示RF方法在分类准确性上表现最佳,提取精度达到了95.75%。3)山仔水库的水华爆发具有显著的季节性和年际波动特征,春季(3—4月)为主要爆发时段,秋季(9—10月)次之,而夏季和冬季的水华强度较低且分布较为分散。随着气温下降与降水量增加,水华的面积在2.2.—2.2.年间持续回落。4)在空间分布方面,水华高发区集中在水库北部狭窄水道和东南、西南部弯曲支流区域,而中部开阔水域因水体流动性强,水华频率相对较低。本研究为山仔水库的藻类水华监测提供了有效的遥感技术支持,可为水生态环境管理和水华预警提供科学依据。

关键词：水华监测富营养化水库 Sentinel-2.MSI 遥感

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The OsFTIP6-OsHB2.-OsMYBR57 module regulates drought response in rice

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Molecular Plant 2022年第7期15卷 1227-1242页

作者： Lijia yang Ying chen Liang Xu Jiaxuan Wang Haoyue Qi Jiazhuo Guo Liang Zhang Jun Shen Huanyu Wang Fan Zhang Lijun Xie {2. Zhu Peitao Lü Qian Qian Hao Yu Shiyong Song State Key Laboratory of Rice Biology Zhejiang Provincial Key Laboratory of Crop Genetic ResourcesInstitute of Crop ScienceCollege of Agriculture and BiotechnologyZhejiang UniversityHangzhou 310058China State Key Laboratory of Rice Biology China National Rice Research InstituteHangzhou 311400China College of Horticulture FAFU-UCR Joint Center for Horticultural Biology and MetabolomicsHaixia Institute of Science and TechnologyFujian Agriculture and Forestry UniversityFuzhou 350002China Department of Biological Sciences and Temasek Life Sciences Laboratory National University of SingaporeSingapore 117543Singapore

Plants have evolved a sophisticated set of mechanisms to adapt to drought *** factors play crucial roles in plant responses to various environmental stimuli by modulating the expression of numerous stress-responsive ***,how the crosstalk between different transcription factor families orchestrates initiation of the key transcriptional network and the role of posttranscriptional modification of transcription factors,especially in cellular localization/trafficking in response to stress in rice,remain still largely *** this study,we isolated an Osmybr57 mutant that displays a drought-sensitive phenotype through a genetic screen for drought stress *** found that OsMYBR57,an MYB-related protein,directly regulates the expression of several key drought-related OsbZ/Ps in response to drought *** studies revealed that OsMYBR57 interacts with a homeodomain transcription factor,OsHB2.,which also plays a positive role in drought *** further demonstrate that OsFTIP6 interacts with OsHB2. and promotes the nucleocytoplasmic translocation of OsHB2. into the nucleus,where OsHB2. cooperates with OsMYBR57 to regulate the expression of drought-responsive *** findings have revealed a mechanistic framework underlying the OsFTIP6-0sHB2.-0sMYBR57 module-mediated regulation of drought response in *** OsFTIP6-mediated OsHB2. nucleocytoplasmic shuttling and OsMYBR57-0sHB2. regulation of OsbZIP transcription ensure precise control of expression of OsLEA3 and Rab2.,and thereby regulate the response to water deficiency in rice.

关键词： OsMYBR57 OsHB2. OsFTIP6 drought response nucleocytoplasmic trafficking rice

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Exploration of a Sequential Gp140-Gp145 Immunization Regimen with Heterologous Envs to Induce a Protective Cross-Reactive HIV Neutralizing Antibody Response In Non-human Primates

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Virologica Sinica 2021年第4期36卷 784-795页

作者： Xiangqing Ding Kangli Cao Jing Wang Yanmin Wan Qinyun chen Yanqin Ren Yongtang Zheng Mingzhao Zhu Renrong Tian wenjun Wang chen Zhao Xiaoyan Zhang Jianqing Xu Shanghai Public Health Clinical center and Institutes of Biomedical Sciences Key Laboratory of Medical Molecular VirologyShanghai Medical CollegeFudan UniversityShanghai 201508China Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province Kunming Institute of ZoologyChinese Academy of SciencesKunming 650223China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Infection and Immunity Institute of BiophysicsChinese Academy of SciencesBeijing 100101China College of Life Sciences University of the Chinese Academy of SciencesBeijing 100101China

Raising a heterologous tier 2.neutralizing antibody(nAb)response remains a daunting task for HIV vaccine *** this study,we explored the utility of diverse HIV-1 envelope(Env)immunogens in a sequential immunization scheme as a solution to this *** exploration stemmed from the rationale that gp145,a membrane-bound truncation form of HIV Env,may facilitate the focusing of induced antibody response on neutralizing epitopes when sequentially combined with the soluble gp140 form as immunogens in a prime-boost *** first showed that gp140 DNA prime-gp145 Tiantan vaccinia(TV)boost likely represents a general format for inducing potent nAb response in ***,when examined in rhesus macaque,this modality showed little *** improve the efficacy,we extended the original modality by adding a strong protein boost,namely native-like SOSIP.664 trimer displayed on ferritin-based nanoparticle(NP),which was generated by a newly developed click *** resulting three-immunization regimen succeeded in eliciting tier-2.nAb response with substantial breadth when implemented in rhesus macaque over a short 8-week ***,the elicited nAb response was able to effectively contain viremia upon a heterologous SHIV ***,our studies highlighted that diversification of Env immunogens,in both types and formulations,under the framework of a sequential immunization scheme might open new opportunity toward HIV vaccine development.

关键词： Human immunodeficiency virus type 1(HIV-1) Vaccine Broadly neutralizing antibodies(bnAbs) Sequential immunization Native-like Env trimers Nanoparticle

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The adsorption properties of NaY zeolite for separation of ethylene glycol and 1,2.butanediol: Experiment and molecular modelling

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Green Energy & Environment 2021年第1期6卷 102-113页

作者： Pei Xiong Peng He Yixin qu Liguo Wang Yan Cao Shuang Xu Jiaqiang chen Muhammad Ammar Huiquan Li College of Chemical Engineering Beijing University of Chemical TechnologyBeijing100029China CAS Key Laboratory of Green Process and Engineering National Engineering Laboratory for Hydrometallurgical Cleaner Production TechnologyInstitute of Process EngineeringChinese Academy of SciencesBeijing100190China Sino-Danish Colleg5 University of Chinese Academy of SciencesBeijing100049China Sino-Danish center for Education and research University of Chinese Academy of SciencesBeijing10049China School of Chemical Engineering University of Chinese Academy of SciencesBeijing100049China Dalian national Laboratory for Clean Energy Dalian116023China Department of Chemical Engineering Technology Government College UniversityFaisalabad 38000Pakistan

The separation of ethylene glycol(EG)and 1,2.butanediol(1,2.BDO)azeotrope in the synthesis process of EG via coal and biomass is becoming of increasing commercial and environmental *** adsorption is deemed as the most promising methods because of energy saving and environment *** this paper,NaY zeolite was used to separate 1,2.BDO from EG,and its adsorption properties was then *** isotherms of EG and 1,2.BDO in vapor and liquid phases from 2.8 to 32. K indicated that they fitted Langmuir model quite well,and the NaY zeolite absorbent favored EG more than 1,*** Grand Canonical Monte Carlo(GCMC)and molecular dynamics(MD)simulation techniques were conducted to investigate the competition adsorption and diffusion characteristics in different adsorption *** was observed that EG and 1,2.BDO molecules all have the most probable locations of the center of the 12.membered ring near the Na *** diffusivities of EG are lower than those of 1,2.BDO at the same adsorption *** last,the breakthrough curves of the binary mixture regressed from the empirical Dose–Response model in fixed-bed column showed that the adsorption selectivity of EG could reach to as high as 2.43,verified that the NaY zeolite could effectively separate EG from 1,*** work is also helpful for further separation of other dihydric alcohol mixtures from coal and biomass fermentation.

关键词： Adsorption mechanism Ethylene glycol(EG) 1,2.Butanediol(1,2.BDO) NaY zeolite Fixed-bed column tests

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Recent advances in electrospun electrode materials for sodium-ion batteries

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Journal of Energy Chemistry 2021年第3期30卷 225-241页

作者： Yao Wang Yukun Liu Yongchang Liu Qiuyu Shen chengcheng chen Fangyuan Qiu Ping Li Lifang Jiao Xuanhui qu beijing Advanced Innovation center for Materials Genome Engineering Institute for Advanced Materials and TechnologyUniversity of Science and Technology BeijingBeijing 100083China Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) Nankai UniversityTianjin 300071China China Electronic Product Reliability and Environmental Testing research Institute(CEPREI) Guangzhou 510610GuangdongChina

Sodium-ion batteries(SIBs)have been considered as an ideal choice for the next generation large-scale energy storage applications owing to the rich sodium resources and the analogous working principle to that of lithium-ion batteries(LIBs).Nevertheless,the larger size and heavier mass of Na^(+)ion than those of Li^(+)ion often lead to sluggish reaction kinetics and inferior cycling life in SIBs compared to the LIB *** pursuit of promising electrode materials that can accommodate the rapid and stable Na-ion insertion/extraction is the key to promoting the development of SIBs toward a commercial ***-dimensional(1 D)nanomaterials demonstrate great prospects in boosting the rate and cycling performances because of their large active surface areas,high endurance for deformation stress,short ions diffusion channels,and oriented electrons transfer ***,as a versatile synthetic technology,features the advantages of controllable preparation,easy operation,and mass production,has been widely applied to fabricate the 1 D nanostructured electrode materials for *** this review,we comprehensively summarize the recent advances in the sodium-storage cathode and anode materials prepared by electrospinning,discuss the effects of modulating the spinning parameters on the materials’micro/nano-structures,and elucidate the structure-performance correlations of the tailored ***,the future directions to harvest more breakthroughs in electrospun Na-storage materials are pointed out.

关键词： Sodium-ion batteries Electrospinning Electrode materials Nanostructures Structure-performance correlations

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