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Checklist of marine fishes in the Beibu Gulf:fish classification,resource protection,and biodiversity challenge

Journal of Oceanology and Limnology 2025年第1期43卷 232-247页

作者： Zhisen LUO Murong YI Xiaodong yanG Xiao CHEN Jinxi WANG Changping JIANG Fengming liu Konglan LUO Xiongbo HE Hung-Du LIN Bin KANG Yunrong yan College of Fisheries Guangdong Ocean UniversityZhanjiang 524088China College of Marine Sciences South China Agricultural UniversityGuangzhou 510642China Fisheries College Ocean University of ChinaQingdao 266003China Guangdong Provincial Engineering and Technology Research Center of Far Sea Fisheries Management and Fishing of South China Sea Guangdong Ocean UniversityZhanjiang 524088China

Marine fish diversity in the Beibu Gulf from 2014 to 2022 was analyzed,using various methods including at-sea fisheries resource surveys,fishing port surveys,underwater survey techniques,and data from literature,books,and databases,from which 1059 fish species across 40 orders,166 families,and 503 genera were *** them,Acanthuriformes displayed the highest diversity,followed by Carangiformes and ***,eight alien species were found in the Beibu *** International Union for Conservation of Nature(IUCN)Red List assessment revealed 51threatened species,primarily cartilaginous *** changes affected 88.70%of species due to classification adjustments,misidentifications,and junior *** study contributed new data of the gulf,including one additional order,six new families,34 new genera,and 81 new species,emphasizing the dynamic nature of marine *** diversity in the gulf was relatively lower than the broader South China Sea,attributed to limited habitats and survey *** survey methods,such as gill nets,trap nets,and underwater cameras,yielded varying *** currents may have transported deep-sea species into the Beibu Gulf,leading to accidental *** gaps exist in unexplored areas,warranting further ***,the Beibu Gulf hosts significant marine biodiversity,but taxonomic challenges and undiscovered species require new research and conservation efforts.

关键词： northwestern South China Sea new record taxonomic change fish diversity survey method

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Allelic variation in the promoter of WRKY22 enhances humid adaptation of Arabidopsis thaliana

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Molecular Plant 2025年第1期18卷 42-58页

作者： Ruyun Liang Luna Tan Xiang Guo Shangling Lou Xuming Dan Yu Han Cheng Zeng Han Zhang Kai yang Liyang Chen Xin Liang Meng liu Mengyun Guo Kangqun Yin Si Tang yan Song Xuemeng Gao Shaobo Gu Jing Hou Yingjun Yao Ruijia Zhang Jin yan Wensen Fu Xuerui Li Yongqi Hu Yao liu Wei liu Qiusai Wu Zhen yan Weitao Jia Binhua Hu Jing Wang Jianquan liu Huanhuan liu Key Laboratory for Bio-resources and Eco-environment&State Key Lab of Hydraulics&Mountain River Engineering Sichuan Zoige Alpine Wetland Ecosystem National Observation and Research StationKey Laboratory for Bio-resource and Eco-environment of Ministry of EducationCollege of Life SciencesSichuan UniversityChengdu 610065China Institute of Biotechnology and Nuclear Technology Sichuan Academy of Agricultural SciencesChengduSichuan 610066China Chongqing Institute of Green and Intelligent Technology Chinese Academy of SciencesChongqingChina

Submergence stress tolerance is a complex trait governed by multiple *** of its wide distribution across arid and humid regions,Arabidopsis thaliana offers an opportunity to explore the genetic components and their action mechanisms underlying plant adaptation to submergence *** this study,using map-based cloning we identified WRKY22 that activates RAP2.12,a locus previously identified to contribute to the submergence stress response,to regulate plant humid adaptation possibly through ethylene signal transduction in ***22 expression is inhibited by ARABIDOPSIS RESPONSE REGULATORs(ARRs)but activated by the WRKY70 transcription *** accessions from humid environments,a two-nucleotide deletion in the WRKY22 promoter region prevents binding of phosphorylated ARRs,thereby maintaining its high *** of the ARR-binding element in the WRKY22 promoter underwent strong positive selection during colonization of *** in the humid yangtze River ***,the WRKY70-binding motif in the WRKY22 promoter shows no variation between accessions from humid and arid *** findings together establish a novel signaling axis wherein WRKY22 plays a key role in regulating the adaptive response that enables *** to colonize contrasting ***,we further showed functional conservation of this locus in Brassica napus,suggesting that modulating this axis might be useful in the breeding of flood-tolerant crop varieties.

关键词： WRKY22 RAP2.12 WRKY70 ARRs natural variation submergence tolerance

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N-P fertilization did not reduce AMF abundance or diversity but alter AMF composition in an alpine grassland infested by a root hemiparasitic plant

N-P fertilization did not reduce AMF abundance or diversity ...

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中国菌物学会2018年学术年会

作者： Xue-Zhao Wang Xiao-Lin Sui yan-yan liu Lei Xiang Ting Zhang Ai-Rong Li Department of Economic Plants and Biotechnology Yunnan Key Laboratory for Wild Plant ResourcesKunming Institute of BotanyChinese Academy of Sciences Department of Grassland Science College of Animal Science and TechnologyNorthwest A&F University Key Laboratory of Biogeography and Bioresource in Arid Land Xinjiang Institute of Ecology and GeographyChinese Academy of Sciences

Fertilization has been shown to have suppressive effects on arbuscular mycorrhizal fungi（AMF） and root hemiparasites separately in numerous investigations, but its effects on AMF in the presence of root hemiparasites remain untested. In view of the contrasting nutritional effects of AMF and root hemiparasites on host plants, we tested the hypothesis that fertilization may not show strong suppressive effects on AMF when a plant community was infested by abundant hemiparasitic plants. Plants and soil samples were collected from experimental field plots in Bayanbulak Grassland, where N and P fertilizers had been applied for three continuous years for control against a spreading root hemiparasite, Pedicularis kansuensis. Shoot and root biomass of each plant functional group were determined. Root AMF colonization levels, soil spore abundance, and extraradical hyphae length density were measured for three soil depths（0-10 cm, 10-20 cm, 20-30 cm）. Partial 18 S rRNA gene sequencing was used to detect AMF diversity and community composition. In addition, we analyzed the relationship between relative abundance of different AMF genera and environmental factors using Spearman’s correlation method. In contrast to suppressive effects reported by many previous studies, fertilization showed no significant effects on AMF root colonization or AMF species diversity in the soil. Instead, a marked increase in soil spore abundance and extraradical hyphae length density were observed. However, fertilization altered relative abundance and AMF composition in the soil. Our results support the hypothesis that fertilization does not significantly influence the abundance and diversity of AMF in a plant community infested by P. kansuensis.

关键词： Arbuscular mycorrhizal fungi fertilization community structure alpine grassland ecosystem root hemiparasitic plants Pedicularis

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Distributions and risk assessment of heavy metals in solid waste in lead-zinc mining areas and across the soil, water body, sediment and agricultural product ecosystem in their surrounding areas

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China Geology 2025年第1期8卷 92-106页

作者： Zhi-qiang Wu Hai-ying Li liu-yan Lü Guo-jun Liang Ting-ting Wu Jiang-xia Zhu No.117 Geological Team Bureau of Geology and Mineral Exploration and Development of Guizhou ProvinceGuiyang 550023China Ecological Environment Monitoring Center of Guizhou Province Guiyang 550023China Guizhou Institute of Geological Survey Guiyang 550081China Environmental Engineering Assessment Center of Anshun City Anshun 561000China Environmental Emergency Center of Anshun City Anshun 561000China

To identify the root causes of heavy metal contamination in soils as well as prevent and control such contamination from its sources,this study explored the accumulation patterns and ecological risks of heavy metals like Cd and Pb in solid waste in mining areas and across the water body,sediment,soil and agricultural product ecosystem surrounding the mining *** on the residual solid waste samples in lead-zinc deposits in a certain area of Guizhou Province,along with samples of topsoils,irrigation water,river sediments,and crops from surrounding *** study analyzed the distributions of eight heavy metals,i.e.,Cd,As,Cr,Hg,Pb,Zn,Cu,and Ni,in the samples through field surveys and sample ***,this study assessed the contamination levels and ecological risks of heavy metals in soils,sediments,and agricultural products using methods such as the single-factor index,Nemerow composite index,and potential ecological risk *** results indicate that heavy metals in the solid waste samples all exhibited concentrations exceeding their risk screening values,with 60%greater than their risk intervention *** soils and sediments demonstrate slight and moderate comprehensive ecological risks of heavy *** single-factor potential ecological risks of heavy metals in both the soil and sediment samples decreased in the order of Hg,Cd,Pb,As,Cu,Zn,Cr,and Ni,suggesting the same sources of heavy metals in the soils and *** of the agricultural product samples exhibited over-limit concentrations of heavy metals dominated by Cd,Pb,Ni,and Cr,excluding Hg and *** agricultural product assessment using the Nemerow composite index reveals that 35%of the agricultural product samples reached the heavy metal contamination level,implying that the agricultural products from farmland around the solid waste dumps have been contaminated with heavy *** eight heavy metals in the soil,sediment,and agricultural product samples manifested hig

关键词： Lead-zinc mining area Solid waste Soil Water body Sediment Agricultural product Nemerow composite index Cd,Pb,Ni,Cr elements Heavy metal contamination Ecological risk assessment Coefficients of variation(CVs) Environmental restoration engineering

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Nanomaterials-mediated lysosomal regulation:a robust protein-clearance approach for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第2期20卷 424-439页

作者： Mengqi Hao Jianjian Chu Tinglin Zhang Tong Yin Yuankai Gu Wendanqi Liang Wenbo Ji Jianhua Zhuang yan liu Jie Gao You Yin Department of Neurology Second Affiliated Hospital of Naval Medical University(Shanghai Changzheng Hospital)ShanghaiChina School of Health Science and Engineering University of Shanghai for Science and TechnologyShanghaiChina Changhai Clinical Research Unit Shanghai Changhai HospitalNaval Medical UniversityShanghaiChina Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Neurology Shanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina

Alzheimer’s disease is a debilitating,progressive neurodegenerative disorder characterized by the progressive accumulation of abnormal proteins,including amyloid plaques and intracellular tau tangles,primarily within the ***,crucial intracellular organelles responsible for protein degradation,play a key role in maintaining cellular *** studies have suggested a link between the dysregulation of the lysosomal system and pathogenesis of neurodegenerative diseases,including Alzheimer’s *** the normal physiological function of lysosomes hold the potential to reduce the pathological burden and improve the symptoms of Alzheimer’s ***,the efficacy of drugs in treating Alzheimer’s disease is limited,with major challenges in drug delivery efficiency and ***,nanomaterials have gained widespread use in Alzheimer’s disease drug research owing to their favorable physical and chemical *** review aims to provide a comprehensive overview of recent advances in using nanomaterials(polymeric nanomaterials,nanoemulsions,and carbon-based nanomaterials)to enhance lysosomal function in treating Alzheimer’s *** review also explores new concepts and potential therapeutic strategies for Alzheimer’s disease through the integration of nanomaterials and modulation of lysosomal *** conclusion,this review emphasizes the potential of nanomaterials in modulating lysosomal function to improve the pathological features of Alzheimer’s *** application of nanotechnology to the development of Alzheimer’s disease drugs brings new ideas and approaches for future treatment of this disease.

关键词： Alzheimer’s disease autophagy dysfunction lysosomal acidification lysosomal system nanomaterials neurodegenerative diseases

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Impact of net-zero emissions on atmospheric CO2 concentration in China: Ideal simulations based on the GEOS-Chem model

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Science China Earth Sciences 2025年第3期68卷 867-881页

作者： Jingye TAN Jun WANG Huiqin MAO Hengmao WANG Zhiqiang liu Meirong WANG Ran yan Xunmei WANG Fei JIANG Frontiers Science Center for Critical Earth Material Cycling International Institute for Earth System Science Nanjing University Jiangsu Provincial Key Laboratory of Geographic Information Science and Technology Key Laboratory for Land Satellite Remote Sensing Applications of Ministry of Natural Resources School of Geography and Ocean Science Nanjing University Satellite Environmental Application Center Ministry of Environmental Protection CMA Key Open Laboratory of Transforming Climate Resources to Economy Chongqing Institute of Meteorological Sciences State Key Laboratory of Climate System Prediction and Risk Management Key Laboratory of Meteorological Disaster Ministry of EducationCollaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science and Technology Xizang Field Station for Scientific Observation and Research on Atmospheric Water Cycle in Mêdog Xigazê and Mêdog National Climate ObservatoryXizang Meteorological Service

Elevated atmospheric carbon dioxide（CO2） concentrations have caused global climate change such as global warming and more frequent climate extremes. Countries worldwide have proposed carbon neutrality strategies to curb the rising CO2concentrations. To investigate the impact of China's carbon neutrality goal on atmospheric CO2concentrations, we conducted a series of ideal simulations from 2015 to 2019 using a global 3D chemistry transport model, Goddard Earth Observing System Chemistry（GEOS-Chem）. Compared with the column-averaged dry-air mole fraction of atmospheric CO2（XCO2） from Orbiting Carbon Observatory-2（OCO-2） and surface CO2measurements in Obs Pack, we find that GEOS-Chem effectively reproduces the spatiotemporal variability of CO2. The model exhibits a root mean square error（RMSE） of 1.51 ppm（R2=0.89） for OCO-2 XCO2in China and 2.65 ppm（R2=0.75） for surface CO2concentrations at the WLG station. Further, compared to 2.83 ppm yr-1in the control experiment, we suggest that net-zero CO2emissions in China decelerate the increasing trends of XCO2to 1.81 ppm yr-1,making a decrease of approximately 35.89%. Meanwhile, the seasonal cycle amplitude（SCA） of XCO2is moderately reduced from 7.39±0.81 to 6.75±0.70 ppm, representing a relative reduction of 9.91%. Spatially, net-zero CO2emissions induce a more significant decrease in XCO2trends over northern and southern China, while their impact on SCA is more evident in northern and northeastern China. Moreover, ideal experiments demonstrate that zero fossil CO2emissions lead to a greater attenuation of the linear trends of XCO2by 40.81%, while the absence of terrestrial CO2sinks largely diminishes the SCA by 16.61%. Additionally,trends and SCA in surface CO2concentrations exhibit almost identical decreasing responses to net-zero CO2emissions but display greater sensitivities compared to XCO2. Overall, our study underscores the potential of China's carbon neutrality goal in mitigating global warming, underscoring the need

关键词： XCO2 GEOS-Chem Carbon neutrality Net-zero emissions Surface CO2 concentrations

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Clinical value of combining epirubicin with mindfulness intervention in patients with urinary system tumors and depression

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World Journal of Psychiatry 2025年第1期15卷 54-62页

作者： Juan liu yan-Ping Guo yan-Mei Lu Bei-Lin Wang Department of Urology Surgery Zhumadian Central HospitalZhumadian 463000Henan ProvinceChina Department of Psychiatry Zhumadian Mental HospitalZhumadian 463000Henan ProvinceChina

BACKGROUND Urinary system tumors often cause negative psychological symptoms,such as depression and dysphoria which significantly impact immune function and indirectly affect cancer *** epirubicin(EPI)is recommended by the European Association of Urology and can improve prognosis,its long-term use can cause toxic side effects,reduce treatment compliance,and increase psycho-logical ***,an appropriate intervention mode is *** This was a retrospective study including 110 patients with urinary system tumors and depression admitted to Zhumadian Central Hospital between March 2021 and July *** were divided into conventional(n=55)and joint inter-vention(n=55)*** conventional group received mitomycin and routine nursing,while the joint intervention group received EPI and mindfulness *** groups underwent three cycles of *** function(CD4+cells,CD8+cells,CD4+/CD8+ratio),tumor marker levels[urinary bladder cancer antigen(UBC),bladder tumor antigen(BTA)and nuclear matrix protein 22(NMP22)],quality of life questionnaire-core 30(QLQ-C30),17-item Hamilton depression scale(HAMD-17),and cancer-related fatigue[cancer fatigue scale(CFS)]were *** reactions and nursing satisfaction were recorded and *** Post-intervention,CD4+,CD8+,and CD4+/CD8+levels increased in both groups,with the joint intervention group showing more significant improvement(P<0.05).Tumor marker levels(NMP22,BTA,and UBC)were lower in the joint intervention group compared to the conventional group(P<0.05).The joint intervention group also showed a greater reduction in HAMD-17 scores(9.38±3.12 vs 15.45±4.86,P<0.05),higher QLQ-C30 scores,and lower CFS scores(both P<0.05).Additionally,the joint intervention group had a lower incidence of adverse reactions and higher nursing satisfaction(P<0.05).CONCLUSION EPI combined with mindfulness intervention significantly improved clinical outcomes in patients with urinar

关键词： Urinary system tumor Bladder cancer Prostate cancer Depression Epirubicin

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Hypoxia-inducible factor 1-alpha and lactate dehydrogenase-A axis in metabolic changes and aggression in esophageal squamous-cell carcinoma

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World Journal of Gastrointestinal Oncology 2025年第3期17卷 322-333页

作者： Xia Chen Hai-yan liu Wu-Bi Zhou Li-Li Zhang Jian Huang Da-Wei Bao Department of Pathology The Affiliated Huaian No.1 People's Hospital of Nanjing Medical UniversityHuai’an 223300Jiangsu ProvinceChina

BACKGROUND Esophageal squamous-cell carcinoma(ESCC)is a highly aggressive cancer,predominantly affecting populations in Eastern Asia and parts of *** pathogenesis is influenced by both genetic and environmental *** recent therapeutic advances,survival rates remain dismal,underscoring an urgent need for novel therapeutic *** To investigate the role of hypoxia-inducible factor 1-alpha(HIF1A)in the progression of ESCC and its impact on the metabolic enzyme lactate dehydrogenase A(LDHA),which is crucial for the glycolytic pathway in hypoxic tumor *** Utilizing transcriptomic data from multiple public databases,we analyzed differential gene expression and conducted gene ontology and transcription factor network *** regulatory impact of HIF1A on LDHA was specifically examined through integrative analysis with HIF1A ChIP-seq data and confirmed via siRNA-mediated knockdown experiments in ESCC cell *** Our findings reveal a significant upregulation of HIF1A in ESCC tissues,associated with poor ***1A directly regulates LDHA,enhancing glycolysis under hypoxic conditions and contributing to tumor *** of HIF1A in cell lines not only reduced LDHA expression but also altered key pathways related to cell cycle and *** The critical role of the HIF1A-LDHA axis in ESCC highlights its potential as a therapeutic target,underscoring the need for future clinical trials to validate the efficacy of HIF1A inhibitors in enhancing treatment outcomes.

关键词： Esophageal squamous-cell carcinoma Hypoxia-inducible factor 1-alpha Lactate dehydrogenase A Metabolic reprogramming Therapeutic target

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Flavones in pomelo peel resist fibril formation of human islet amyloid polypeptide

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Chinese Herbal Medicines 2025年第1期17卷 166-177页

作者： Cuiyun Gao Zhiruo Wan yan liu Yuting Meng Xu Chen Xiaohan Tang Lingyu Hang Hailong Yuan Department of Pharmacy Air Force Medical Center Air Force Medical University

Objective:Exploring the formation and aggregation of human islet amyloid polypeptide(hIAPP)(amylin)fibers is significant for promoting the prevention and treatment of type II diabetes mellitus(T2DM).Flavones in pomelo peel have visible biological activity in the anti-diabetes *** present study aimed to investigate the effects of five flavones [naringin(NRG),narirutin(NRR),nobiletin(NOB),sinensetin(SIN),and neohesperidin(NHP)] in pomelo peel on peptide aggregation and explore its possible *** cell viability of flavones against peptide aggregation was also ***:The thioflavin T(ThT) assay and transmission electron microscopy(TEM) were used for evaluating the inhibition and disaggregation of flavones on peptide *** interaction mechanism was analyzed by endogenous fluorescence,molecular dynamics(MD) simulations,ultraviolet spectroscopy(UV) and isothermal titration calorimetry(ITC) *** 3-[4,5-dimethylthiazol-2-y l]-2,5-diphenyl tetrazolium bromide(MTT) and immune assays were performed to characterize the cell viability of flavones against peptide ***:The five flavones showed a decrease in fluorescence intensity,fiber number and size under incubation with different molar ratios of *** compounds can bind to the aromatic tyrosine(Tyr)residueTyr 37,resulting in the intrinsic fluorescence quenching of the *** flavones can form hydrogen bonds with hIAPP,which is likely to be based on their phenolic hydroxyl *** showed strong binding affinity with *** reaction system of NRG and NRR observed an exothermic reaction,and the others were endothermic *** absorption peaks of the compounds with hIAPP changed and showed hypochromic effects,indicating that there may be π-π stacking *** noticeably increased the cell viability in the presence of amyloid peptides and reduced the absorption intensity induced by peptide ***:A total of five flav

关键词： flavones human islet amyloid polypeptide inhibition interaction pomelo peel peptide aggregation

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Interaction of Ca^(2+)and Fe^(3+)in co-precipitation process induced by Virgibacillus dokdonensis and its application

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Journal of Environmental Sciences 2025年第1期147卷 131-152页

作者： Huaxiao yan Yuping liu Haojuan Zhang Shengping Jin Zuozhen Han Jusun Woo Maurice E.Tucker Long Meng Xiangqun Chi Chao Han yanyang Zhao Yueming Zhao Hui Zhao College of Chemical and Biological Engineering College of Earth Science and EngineeringShandong Provincial Key Laboratory of Depositional Mineralization and Sedimentary MineralsShandong University of Science and TechnologyQingdao 266590China Laboratory for Marine Mineral Resources Center for Isotope Geochemistry and GeochronologyQingdao National Laboratory for Marine Science and TechnologyQingdao 266237China School of Earth and Environmental Sciences Seoul National UniversitySeoul 08826Korea School of Earth Sciences University of BristolBristol BS81RJUK Cabot Institute University of BristolCantock’s CloseBristol BS81UJUK Qingdao West Coast New District First High School Qingdao 266555China

Biomineralization has garnered significant attention in the field of wastewater treatment due to its notable cost reduction compared to conventional *** reinjection water from oilfields containing an exceedingly high concentration of calcium and ferric ions will pose amajor hazard in ***,the utilization of biomineralization for precipitating these ions has been scarcely investigated due to limited tolerance among halophiles towards such extreme *** this study,free and immobilized halophiles Virgibacillus dokdonensis were used to precipitate these ions and the effects were compared,at the same time,biomineralizationmechanisms and mineral characteristicswere further *** results showthat bacterial concentration and carbonic anhydrase activitywere higher when additionally adding ferric ion based on calcium ion;the content of protein,polysaccharides,deoxyribonucleic acid and humic substances in the extracellular polymers also increased compared to *** ions were biomineralized into calcite and vaterite with mul-tiple *** to iron doping,the crystallinity and thermal stability of calcium carbonate decreased,the content of O-C=O,N-C=OandC-O-PO_(3) increased,the stable carbon isotope values became much more negative,andβ-sheet in minerals *** calcium concentrations facilitated ferric ion precipitation,while ferric ions hindered calcium *** immobilized bacteria performed better in ferric ion removal,with a precipitation ratio exceeding 90%.Free bacteria performed better in calcium removal,and the precipitation ratio reached a maximum of 56%.This research maybe provides some reference for the co-removal of calcium and ferric ions from the oilfield wastewater.

关键词： Calcium carbonate Calcium ion Ferric ion Biomineralization Co-removal Immobilization

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