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Role of Diffusion-weighted and Contrast-enhanced Magnetic Resonance Imaging in Differentiating Activity of Ankylosing Spondylitis

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Chinese Medical Journal 2017年第11期130卷 1303-1308页

作者： Ying-Hua Zhao yan-yan Cao Qun Zhang Ying-Jie mei Ji-Jie Xiao Shao-Yong Hu Wei Li Shao-Lin Li Oepartment of Radiology Third Affiliated Hospital of Southern Medical University Orthopaedic Hospital of Guangdong Province Guangzhou Guangdong 510630 China Department of Rheumatology Hospital of Integrated Traditional Chinese Medicine and Western Medicine of Southern Medical University Guangzhou Guangdong 510315 China Department of Rheumatology Third Affiliated Hospital of Southern Medical University Orthopaedic Hospital of Guangdong Province Guangzhou Guangdong 510630 China Department of MR Clinical Science Philips Healthcare Guangzhou Guangdong 510055 China

Background： Previous studies showed that combining apparent diffusion coefficient （ADC） value with the Spondyloarthritis Research Consortium of Canada （SPARCC） index value might provide a reliable evaluation of the activity of ankylosing spondylitis （AS）, and that contrast-enhanced （CE） magnetic resonance imaging （MRI） is unnecessary. However, the results were based on confirming only a small random sample. This study aimed to assess the role of CE-MRI in differentiating the disease activity of AS by comparingADC value with a large sample. Methods： A total of l 15 patients with AS were enrolled in accordance with Bath AS Disease Activity Index and laboratory indices, and 115 patients were divided into two groups, including active group （n = 69） and inactive group （n 46）. SPARCC, ASI, and ADC values were obtained from the short tau inversion recovery （STIR）, diffusion-weighted imaging （DWI）, and CE-MRI, respectively. One-way analysis of variance and receiver operating characteristic analysis were performed for all parameters. Results： The optimal cutoff values （with sensitivity, specificity, respective area under the curve, positive likelihood ratio, and negative likelihood ratio） for the differentiation between active and inactive groups are as follows： SPARCC = 6 （72.06%, 82.61%, 0.836, 4.14, 0.34）; ASI （%） 153 （80.6%, 84.78%, 0.819, 5.3, 0.23）; ADC value - 1.15 × 10 3 mm2/s （72.73% 81.82%, 0.786, 4, 0.33）. No statistical differences were found among the predictive values of SPARCC, △SI, and ADC. Multivariate analysis showed no significant difference between the combination of SPARCC and ADC values with and without ASI. Conclusions： Using large sample, we concluded that the combination of STIR and DWI would play significant roles in assessing the disease activity, and CE-MRI sequence is not routinely used in imaging of AS to avoid renal fibrosis and aggravation of kidney disease.

关键词： Activity Ankylosing Spondylitis Diffusion-weighted Imaging Enhanced Magnetic Resonance Imaging

基于OpenCV的摄像头动态手势轨迹识别及其应用

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计算机应用 2012年第A1期32卷 128-133页

作者：江超艾矫燕广西大学电气工程学院南宁530004

利用OpenCV计算机视觉库在vs2008平台上设计了一个基于实时摄像头的集动态手势检测、动态手势跟踪、动态手势轨迹识别的应用。首先,该应用基于静止的背景更新,利用背景差分检测运动手势,再结合颜色直方图的粒子滤波进行动态手势跟踪,最... 详细信息

利用OpenCV计算机视觉库在vs2008平台上设计了一个基于实时摄像头的集动态手势检测、动态手势跟踪、动态手势轨迹识别的应用。首先,该应用基于静止的背景更新,利用背景差分检测运动手势,再结合颜色直方图的粒子滤波进行动态手势跟踪,最后利用隐马尔可夫模型(HMM)进行运动轨迹识别。在运动检测部分结合了背景差分图与通过颜色直方图获得的反投影图,达到比较满意的实时运动检测效果;在运动手势跟踪部分,改进的颜色直方图的粒子跟踪能够在经过类肤色人脸的干扰后迅速地找回运动手势,基本达到了跟踪的要求,但是同时对于HMM识别轨迹时需要的运动轨迹序列采集造成了影响;在识别轨迹部分,HMM的训练达到了识别的要求,但是识别的效果主要取决于实时运动轨迹序列的采集工作与采集方法的优化。

关键词： OpenCV 摄像头粒子跟踪 HMM 轨迹识别

A Point Mutation in an F-Box Domain-Containing Protein Is Responsible for Brown Hull Phenotype in Rice

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Rice science 2016年第1期23卷 1-8页

作者： XU Xia ZHANG Xiao-bo SHI Yong-feng WANG Hui-mei FENG Bao-hua LI Xiao-hong HUANG Qi-na SONG Li-xin GUO Dan HE yan WU Jian-li State Key Laboratory of Rice Biology Chinese National Center for Rice ImprovementChina National Rice Research Institute

The accumulation of pigments affects the color of rice hulls while only limited information is known about its underlying mechanisms. In the present study, a rice brown hull 6（bh6） mutant was isolated from an ethane methyl sulfonate（EMS）-induced IR64 mutant bank. Brown pigments started to accumulate in bh6 rice hulls after heading and reached a higher level in mature seeds. Some major agronomic traits including panicle length and 1000-grain weight in bh6 were significantly lower than those in its corresponding wild type IR64, while other agronomic traits such as plant height, growth duration and seed-setting rate were largely similar between the two genotypes. The analysis of pigment content showed that the contents of total flavonoids and anthocyanin in bh6 hulls were significantly higher than those in IR64 hulls. Our results showed that the brown hull phenotype in bh6 was controlled by a single recessive gene which locates on the long arm of chromosome 9. Sequencing analysis detected a single base substitution（G/A） at position 1013 of the candidate gene（LOC_Os09g12150） encoding an F-box domain-containing protein（FBX310）. Functional complementation experiment using the wild type allele can rescue the phenotype in bh6. Thus, we named this mutated gene as Os FBX310^（bh6）, an allele of OsFBX310 functioning as an inhibitor of brown hull. The isolation of Os FBX310^（bh6） and its wild type allele can provide useful experimental materials and will facilitate the studies on revealing the mechanisms of flavonoid metabolism in monocot plants.

关键词： Oryza sativa L brown hull mutant OsFBX310 gene flavonoid metabolism

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基于TDI-CCD成像像移分析及图像复原

宇航学报 2008年第2期29卷 675-678页

作者：焦斌亮闫旭辉燕山大学信息科学与工程学院秦皇岛066004

介绍了时间延迟积分电荷耦合器件(TDI-CCD)工作原理及成像特点。基于调制传递函数(MTF)对TDI-CCD的像移进行了分析。根据TDI-CCD像移的产生机理,建立图像退化的数学模型,提出了一种有效估计模糊图像系统点扩散函数的方法,并对运动模糊... 详细信息

介绍了时间延迟积分电荷耦合器件(TDI-CCD)工作原理及成像特点。基于调制传递函数(MTF)对TDI-CCD的像移进行了分析。根据TDI-CCD像移的产生机理,建立图像退化的数学模型,提出了一种有效估计模糊图像系统点扩散函数的方法,并对运动模糊图像进行半盲恢复。实验结果证明了算法的可行性和有效性。

关键词： TDI-CCD 调制传递函数像移点扩散函数图像恢复

Serum vitamin D_3 does not correlate with liver fibrosis in chronic hepatitis C

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World Journal of Gastroenterology 2015年第39期21卷 11152-11159页

作者： yan Ren mei Liu Jing Zhao Feng Ren Yu Chen Jun-Feng Li Jing-Yun Zhang Feng Qu Jin-Lan Zhang Zhong-Ping Duan Su-Jun Zheng Artificial Liver Center Beijing You An Hospital Capital Medical University Institute of Liver Diseases Beijing YouA n Hospital Capital Medical University State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical College

AIM: To investigate the relationship between serum vitamin D3 levels and liver fibrosis or inflammation in treatment-naive Chinese patients with chronic hepatitis C(CHC).METHODS: From July 2010 to June 2011, we enrolled 122 CHC patients and 11 healthy controls from Dingxicity, Gansu Province, China. The patients were infected with Hepatitis C virus(HCV) during blood cell retransfusion following plasma donation in 1992-1995, and had never received antiviral treatment. At present, all the patients except two underwent liver biopsy with ultrasound guidance. The Scheuer Scoring System was used to evaluate hepatic inflammation and the Metavir Scoring System was used to evaluate hepatic fibrosis. Twelve-hour overnight fasting blood samples were collected in the morning of the day of biopsy. Serum levels of alanine aminotransferase, aspartate aminotransferase, total bilirubin, direct bilirubin, cholineste rase, prothrom binactivity, albumin, γ-glutamyl transpeptidase, hemoglobin, calcium and phosphorus were determined. Serum HCV RNA levels were measured by real-time PCR. Serum levels of 25-hydroxyvitamin D3 [25(OH)D3] and 24,25-dihydroxyvitamin D3 [24,25(OH)2D3] were measured by high-performance liquid chromatography tandem mass spectrometry.R E S U LT S : Serumlevels of 2 5(OH) D3 but not 24,25(OH)2D3 were significantly lower in CHC patients than in control subjects. Serum 25(OH)D3 levels did not correlate with liver fibrosis, inflammation, patient age, or levels of alanine aminotransferase, aspartate aminotransferase, total bilirubin, direct bilirubin, prothrombin activity, cholinesterase or HCV RNA. However, serum 25(OH)D3 levels did correlate with serum 24,25(OH)2D3 levels. Serum 25(OH)D3 and 24,25(OH)2D3 levels, and the 25(OH)D3/24,25(OH)2D3 ratio, have no difference among the fibrosis stages or inflammation ***: We found that serum levels of 25(OH)D3 and its degradation metabolite 24,25(OH)2D3 did not correlate with liver fibrosis in treatment-naive Chi

关键词： Hepatitis C virus 25-Hydroxyvitamin D3 24,25-Dihyd

Generation of ready to use (RTU) products over China based on Landsat series data

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Big Earth Data 2018年第1期2卷 56-64页

作者： Guojin He Zhaoming Zhang Weili jiao Tengfei Long yan Peng Guizhou Wang Ranyu Yin Wei Wang Xiaomei Zhang Huichan Liu Bo Cheng Bo Xiang Institute of Remote Sensing and Digital Earth Chinese Academy of SciencesBeijingChina Hainan Key Laboratory of Earth Observation SanyaChina Sanya Institute of Remote Sensing SanyaChina

Earth observation community has entered into the era of big *** of Landsat sensors have collected massive medium resolution satellite images,which are valuable for long-term land surface *** order to significantly reduce the magnitude of data processing for remote sensing data users,Landsat-based Ready to Use(RTU)products have been *** RTU products,including orthorectified products,land surface reflectance,land surface temperature,large-area mosaic image,and standard image map products,are *** resulting Landsat RTU products are hosted on the RSGS earth observation data sharing web site for free download(http://***/rtu/).These new products will provide consistent,standardized,multi-decadal image data for robust land cover change detection and monitoring across the Earth *** the coming years,CASEarth DataBank system will be constructed,which is an intelligent data service platform for providing not only the RTU products from multi-source satellite data,but also big earth data analysis methods.

关键词： Landsat RTU data product CASEarth DataBank China

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光伏发电系统中滤波器的设计

电源技术 2012年第11期36卷 1670-1673页

作者：徐岩王佼华北电力大学电气与电子工程学院河北保定071003 保定供电公司河北保定071003

太阳能作为一种可再生能源有着广阔的应用前景,光伏发电技术也越来越受到人们的关注。针对光伏并网发电系统中产生的电压纹波和电压尖峰问题,在分析几种常用滤波器性能优缺点的基础上设计了一种新型滤波器——带阻尼的LCL滤波器,并采用... 详细信息

太阳能作为一种可再生能源有着广阔的应用前景,光伏发电技术也越来越受到人们的关注。针对光伏并网发电系统中产生的电压纹波和电压尖峰问题,在分析几种常用滤波器性能优缺点的基础上设计了一种新型滤波器——带阻尼的LCL滤波器,并采用单相半桥逆变电路对其进行pspice仿真,仿真结果验证了所设计滤波器的可行性和合理性,较其它滤波器具有更好的性能,能够满足光伏发电系统的滤波要求。

关键词：光伏系统逆变滤波器仿真

不同镇痛方式对应用低分子肝素全髋置换术患者血液流变学及凝血功能的影响

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中华医学杂志 2010年第17期90卷 1171-1176页

作者：楼小侃严美娟浙江省人民医院麻醉科杭州310014

目的观察不同术后镇痛方式对应用低分子肝素（LMWH）的全髋置换术（THR）患者术后血液流变学和凝血功能的影响.方法择期行THR患者随机分为4组,E0组：术后硬膜外镇痛（PCEA）未用LMWH;EL组：PCEA联合应用LMWH;I0组：术后静脉镇痛（PCI... 详细信息

目的观察不同术后镇痛方式对应用低分子肝素（LMWH）的全髋置换术（THR）患者术后血液流变学和凝血功能的影响.方法择期行THR患者随机分为4组,E0组：术后硬膜外镇痛（PCEA）未用LMWH;EL组：PCEA联合应用LMWH;I0组：术后静脉镇痛（PCIA）未用LMWH;IL组：PCIA联合应用LMWH.于入院检查时（基础值）、术毕、术后24 h、术后48 h及术后7 d抽取静脉血检测血液流变学和凝血功能指标.术后24 h及48 h行视觉模拟评分法（VAS）镇痛评分,术前和术后第7天双下肢血管B超检查,记录并发症的发生情况.结果四组患者静息和活动时VAS评分无差异.EL和IL两组患者下肢静脉血栓阳性率低于I0和E0组,EL和IL之间及I0和E0之间差异无统计学意义.IL组术后恶心的患者数较E0和EL组增多（P＜0.05）.纤维蛋白原浓度术毕和术后24 h时4组患者均低于基础值（P＜0.05）.血浆黏度和全血黏度E0组低于I0组（P＜0.05）,IL和EL组低于I0和E0组（P＜0.05）,IL和EL之间差异无统计学意义.IL和EL术后各时点凝血酶原时间和激活部分凝血活酶时间均较基础值延长（P＜0.05）,且较I0和E0组延长（P＜0.05）.各组间术中和术后出血量差异无统计学意义.结论 THR患者围术期未用LMWH时PCEA改善血液流变学的作用优于***和PCIA联合应用LMWH,均能减少静脉血栓的发生,改善凝血功能和血液流变学指标,且不增加出血,提示应用LMWH时行椎管内麻醉和PCEA是安全可行的.在应用LMWH时,PCEA预防DVT的作用并无明显优势.

关键词：低分子肝素镇痛,硬膜外,静脉关节成形术,置换,髋血栓

Successful cure of a patient with urosepsis using a combination of extracorporeal membrane oxygenation and continuous renal replacement therapy:A case report and literature review

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Chinese Journal of Traumatology 2020年第6期23卷 372-375页

作者： Chun-yan Zhu Ai-Jun Pan Qing mei Ting Chen Department of Critical Care Medicine The First Affiliated Hospital of USTCHefei 230032China Department of Critical Care Medicine The Second People's Hospital of HefeiHefei 230009China

Holmium laser lithotripsy(HLL)is one of the common surgical methods for *** causes minor surgical trauma,but complications are not *** membrane oxygenation(ECMO)treatment of sepsis is common,but venoarterial(VA)-ECMO treatment of urosepsis has not been reported *** this article,we reported a 67-year-old female patient with refractory septic shock caused by HLL under percutaneous nephroscope,involving breathing,heart,kidney and other organs,and organs support treatment was ineffective for the ***,we successfully treated the patient under VA-ECMO with continuous renal replacement therapy(CRRT).Combined ECMO and CRRT may provide a solution for addressing refractory *** we present the case and review relevant literature,so as to provide a treatment strategy for patients with refractory urogenic sepsis and to reduce the mortality rate.

关键词： Extracorporeal membrane oxygenation Continuous renal replacement therapy Sepsis Refractory