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An Overview on the Composition and Age of Upper Crust of Proto-Tethyan Lajishan Intra-oceanic Arc,NE Tibet Plateau

Acta Geologica Sinica(English Edition) 2024年第2期98卷 285-302页

作者： FU Changlei HE Xiaohu yan Zhen jonathan CAITCHISON XIAO Wenjiao WANG Bingzhang LI Wufu LI Yusen SinoProbe Laboratory Institute of GeologyChinese Academy of Geological SciencesBeijing 100037China Key Laboratory of the Northern Qinghai–Tibet Plateau Geological Processes and Mineral Resources Qinghai Geological Survey InstituteXining 810012China Department of Geology School of Earth SciencesYunnan UniversityKunming 650091China School of Earth and Environmental Sciences University of QueenslandBrisbane 4072Australia Xinjiang Institute of Ecology and Geography Chinese Academy of SciencesUrumqi 830011China State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China School of Earth Science and Resources China University of GeosciencesBeijing 100083China

Identification and anatomy of oceanic arcs within ancient orogenic belt are significant for better understanding the tectonic framework and closure process of paleo-ocean *** article summarizes the geological,geochemical,and geochronological characteristics of upper crust of Proto-Tethyan Lajishan intra-oceanic arc and provides new data to constrain the subduction evolution of the South Qilian *** intra-oceanic arc volcanic rocks,including intermediate-mafic lava,breccia,tuff,and minor felsic rocks,are distributed along southern part of the Lajishan ophiolite *** and isotopic compositions indicate that the intermediate-mafic lava were originated from depleted mantle contaminated by sediment melts or hydrous fluids,whereas the felsic rocks were likely generated by partial melting of juvenile mafic crust in intra-oceanic arc *** from felsic rocks yield consistent and concordant ages ranging from 506 to 523 Ma,suggesting these volcanic rocks represent the relicts of upper crust of the Cambrian intra-oceanic *** with the Cambrian forearc ophiolite and accretionary complex,we suggest that the Cambrian intra-oceanic arc in the Lajishan ophiolite belt is belonging to the intra-oceanic arc system which was generated by south-directed subduction in the South Qilian Ocean at a relatively short interval between approximately 530 and 480 Ma.

关键词： volcanic rocks intra-oceanic arc U-Pb age Lajishan ophiolite belt South Qilian Ocean Proto-Tethyan realm

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Calculation of Ecological Footprint Based on Modified Method and Quantitative Analysis of Its Impact Factors——A Case Study of Shanghai

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Chinese Geographical Science 2006年第4期16卷 306-313页

作者： GAO Chengkang JIANG Dahe WANG Dan yan jonathan College of Environmental Science and Engineering Tongji University Shanghai 200092 China Department of Geography Shanghai Normal University Shanghai 200234 China Department of Pacific and International Affairs University of California San Diego USA

Ecological footprint(EF) has attracted much attention internationally as a potential indicator for sustainable *** China,EF has also gained recognition in related fields and ***,some scholars in these fields have proposed alternative methods to calculate EF and have made some *** paper,therefore,begins with the introduction and development of EF in ***,the established methods of EF calculation hold some limitations,such as indicator variance and result *** order to resolve those problems,the authors make a further modification considering the demand of EF as a comprehensive indicator:1) More accurate analysis has been done to divide EF into several parts:imported EF,exported EF,and producible EF,which is the solution to the problem of abnormality in original EF results and can explain abnormal phenomena reasonably.2) Considering the actual situa-tion of Shanghai,amended equivalence factor is brought forward and a matrix is formed with equivalence *** measure can reduce the deviation between the fact and the results.3) The calculation compares local yield with global average yield to analyze the effects of *** based on local yields in different years,the results are more ***,the calculation method is applied to calculating EF of Shanghai from 1980 to 2003,and the subsequent detailed analysis is *** data and results suggest a statistically significant correlation coefficient between EF and GDP,population density and urbanization *** analyzing the process of calculating EF and its results,it can be seen that EF,as a macro-indicator,can not exactly indicate whether development within a region can meet the re-quests of sustainable development,which can be explained by the fact that the result of EF is impacted greatly by sub-jective factors including national policy,available technology,population,***,EF can demonstrate,at least to some degree,the

关键词：上海生态足迹法计算方法定量分析冲击因子可持续发展

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Blastomas of the digestive system in adults:A review

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World Journal of Gastrointestinal Surgery 2024年第4期16卷 1030-1042页

作者： Yu Liu Tony El Jabbour jonathan Somma Yukihiro Nakanishi Saverio Ligato Hwajeong Lee Zhi-yan Fu Department of Pathology LSU Health Sciences Center School of MedicineNew OrleansLA 70112United States Department of Pathology Hartford HealthCareHartfordCT 06102United States Department of Pathology Moffitt Cancer CenterTampaFL 33612United States Department of Pathology and Laboratory Medicine Albany Medical CenterAlbanyNY 12208United States

Blastomas,characterized by a mixture of mesenchymal,epithelial,and undifferentiated blastematous components,are rare malignant neoplasms originating from precursor blast *** review focuses on digestive system blastomas in adult patients,including gastroblastoma,hepatoblastoma,and *** is a biphasic,epitheliomesenchymal tumor,with only sixteen cases reported to *** addition to the characteristic histology,metastasisassociated lung adenocarcinoma transcript 1-glioma-associated oncogene homolog 1 gene fusion is typical,although recently novel ewing sarcoma breakpoint region 1-c-terminal binding protein 1 and patched 1-glioma-associated oncogene homolog 2 fusions have been *** is exceptionally rare in adults and can show a variety of histologic patterns which may cause diagnostic ***,primarily a pediatric tumor,displays acinar differentiation and squamoid nests with other lines of differentiation also present,especially *** approaches for these blastomas include a combination of imaging modalities,histopathological examination,and molecular *** treatment generally involves surgical resection,which may be supplemented by chemotherapy or radiotherapy in some *** vary with gastroblastoma generally showing favorable outcomes post-surgery whereas hepatoblastoma and pancreatoblastoma often have poorer outcomes,particularly in the setting of *** review highlights the complexity of diagnosing and managing these rare adult blastomas as well as the need for ongoing research to better understand their pathogenesis and improve treatment strategies.

关键词： Adult blastomas Gastroblastoma Hepatoblastoma Pancreatoblastoma Digestive system

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High-speed silicon photonic electro-optic Kerr modulation

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Photonics Research 2024年第1期12卷 51-60页

作者： jonathan PELTIER WEIWEI ZHANG LEOPOLD VIROT CHRISTIAN LAFFORGUE LUCAS DENIEL DELPHINE MARRIS-MORINI GUY AUBIN FARAH AMAR DENH TRAN XINGZHAO yan CALLUM G.LITTLEJOHNS CARLOS ALONSO-RAMOS KE LI DAVID J.THOMSON GRAHAM REED LAURENT VIVIEN University Paris-Saclay CNRSCentre for Nanoscience and Nanotechnology(C2N)Palaiseau 91120France University Grenoble Alpes CEALETIGrenoble 38000France Optoelectronics Research Centre Zepler Institute for Photonics and NanoelectronicsFaculty of Engineering and Physical SciencesUniversity of SouthamptonSouthampton SO171BJUK

Silicon-based electro-optic modulators contribute to easing the integration of high-speed and low-power consumption circuits for classical optical communications and data *** the plasma dispersion modulation,an alternative solution in silicon is to exploit the DC Kerr effect,which generates an equivalent linear electro-optical effect enabled by applying a large DC electric *** some theoretical and experimental studies have shown its existence in silicon,limited contributions relative to plasma dispersion have been achieved in high-speed modulation so *** paper presents high-speed optical modulation based on the DC Kerr effect in silicon PIN *** contributions of both plasma dispersion and Kerr effects have been analyzed in different waveguide configurations,and we demonstrated that the Kerr induced modulation is dominant when a high external DC electric field is applied in PIN ***-speed optical modulation response is analyzed,and eye diagrams up to 80 Gbit/s in NRZ format are obtained under a *** of 30 *** work paves the way to exploit the Kerr effect to generate high-speed Pockels-like optical modulation.

关键词： waveguide dispersion effect

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Deciphering microeukaryotic–bacterial co-occurrence networks in coastal aquaculture ponds

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Marine Life Science & Technology 2023年第1期5卷 44-55页

作者： Xiafei Zheng Kui Xu jonathan Naoum Yingli Lian Bo Wu Zhili He Qingyun yan Ninghai Institute of Mariculture Breeding and Seed Industry Zhejiang Wanli UniversityNingbo315100China Environmental Microbiomics Research Center School of Environmental Science and EngineeringState Key Laboratory for BiocontrolSouthern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Sun Yat-Sen UniversityGuangzhou510006China Hubei Key Laboratory of Edible Wild Plants Conservation and Utilization Hubei Engineering Research Center of Special Wild Vegetables Breeding and Comprehensive Utilization TechnologyCollege of Life SciencesHubei Normal UniversityHuangshi435002China Department of Biological Sciences Ecotoxicology of Aquatic Microorganisms LaboratoryGRIL-EcotoQ-TOXENUniversitéDu QuébecÀMontréalSuccursale Centre-VilleMontrealQCCanada Animal Husbandry and Fisheries Research Center of Guangdong Haid Group CO. Ltd.Key Laboratory of Microecological Resources and Utilization in Breeding IndustryMinistry of Agriculture and Rural AffairsGuangzhou510006China

Microeukaryotes and bacteria are key drivers of primary productivity and nutrient cycling in aquaculture *** their diversity and composition have been widely investigated in aquaculture systems,the co-occurrence bipartite network between microeukaryotes and bacteria remains poorly *** study used the bipartite network analysis of high-throughput sequencing datasets to detect the co-occurrence relationships between microeukaryotes and bacteria in water and sediment from coastal aquaculture *** and fungi were dominant phyla in the microeukaryotic–bacterial bipartite networks in water and sediment,*** also had overrepresented links with bacteria in *** microeukaryotes and bacteria were classified as generalists,and tended to have symmetric positive and negative links with bacteria in both water and ***,some microeukaryotes with high density of links showed asymmetric links with bacteria in *** detection in the bipartite network indicated that four microeukaryotes and twelve uncultured bacteria might be potential keystone taxa among the module ***,the microeukaryotic–bacterial bipartite network in sediment harbored significantly more nestedness than that in *** loss of microeukaryotes and generalists will more likely lead to the collapse of positive co-occurrence relationships between microeukaryotes and bacteria in both water and *** study unveils the topology,dominant taxa,keystone species,and robustness in the microeukaryotic–bacterial bipartite networks in coastal aquaculture *** species herein can be applied for further management of ecological services,and such knowledge may also be very useful for the regulation of other eutrophic ecosystems.

关键词： Microeukaryote Bipartite network Interactions Keystone taxa Nestedness

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Unraveling the serial glycosylation in the biosynthesis of steroidal saponins in the medicinal plant Paris polyphylla and their antifungal action

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Acta Pharmaceutica Sinica B 2023年第11期13卷 4638-4654页

作者： Yuegui Chen Qin yan Yunheng Ji Xue Bai Desen Li Rongfang Mu Kai Guo Minjie yang yang Tao jonathan Gershenzon yan Liu Shenghong Li State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China State Key Laboratory of Southwestern Chinese Medicine Resources Innovative Institute of Chinese Medicine and PharmacyChengdu University of Traditional Chinese MedicineChengdu 611137China Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China Max Planck Institute for Chemical Ecology Jena D-07745Germany University of Chinese Academy of Sciences Beijing 100049China

Sugar-sugar glycosyltransferases play important roles in constructing complex and bioactive ***,we characterized a series of UDP-glycosyltransferases responsible for biosynthesizing the branched sugar chain of bioactive steroidal saponins from a widely known medicinal plant Paris polyphylla *** them,a 2'-O-rhamnosyltransferase and three 6'-O-glucosyltrasferases catalyzed a cascade of glycosylation to produce steroidal diglycosides and triglycosides,*** UDP-glycosyltransferases showed astonishing substrate promiscuity,resulting in the generation of a panel of 24 terpenoid glycosides including 15 previously undescribed compounds.A mutant library containing 44 variants was constructed based on the identification of critical residues by molecular docking simulations and protein model alignments,and a mutant UGT91AH1^(Y187A)with increased catalytic efficiency was *** steroidal saponins exhibited remarkable antifungal activity against four widespread strains of human pathogenic fungi attributed to ergosterol-dependent damage of fungal cell membranes,and 2'-O-rhamnosylation appeared to correlate with strong antifungal *** findings elucidated the biosynthetic machinery for their production of steroidal saponins and revealed their potential as new antifungal agents.

关键词： Paris polyphylla var.yunnanensis Steroidal saponins Glycosyltransferases Sugar chain elongation Antifungal activity

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One-pot synthesis of 2,5-bis(hydroxymethyl)furan from biomass derived 5-(chloromethyl)furfural in high yield

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Journal of Energy Chemistry 2023年第1期76卷 421-428,I0011页

作者： Binglin Chen Yunchao Feng Sen Ma Weizhen Xie Guihua yan Zheng Li jonathan Sperry Shuliang yang Xing Tang Yong Sun Lu Lin Xianhai Zeng College of Energy Xiamen UniversityXiamen 361102FujianChina Fujian Engineering and Research Centre of Clean and High-valued Technologies for Biomass Xiamen Key Laboratory of Clean and High-valued Utilization for BiomassXiamen 361102FujianChina Centre for Green Chemical Science University of AucklandAuckland 1142New Zealand

5-(Chloromethyl)furfural(CMF),as a new platform molecular,has become a hot topic in the field of ***,the one-pot conversion of CMF to 2,5-bis(hydroxymethyl)furan(BHMF)in the water phase was demonstrated for the first time.A 91%BHMF yield was obtained over Ru/Cu Oxcatalyst,and BHMF was mainly produced by the consecutive hydrolysis and hydrogenation of CMF with 5-hydroxymethylfurfural(HMF)as an *** studies revealed that the conversion of HMF to BHMF was the rate-determining ***,the characterizations and density functional theory(DFT)calculations further revealed the lower electron density of Ru NPs in Ru/Cu Oxcatalyst,resulting in a larger adsorption energy and a smaller free energy difference for the formation of *** present findings offered a new pathway for biomass-derived diol production through CMF as a potential source.

关键词： 2 5-Bis(hydroxymethyl)furan Hydrolysis Hydrogenation Biomass conversion Heterogeneous catalysis

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Neonatal Dubin-Johnson Syndrome and its Differentiation from Biliary Atresia

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Journal of Clinical and Translational Hepatology 2023年第1期11卷 163-173页

作者： Teng Liu Jing Zhao Jia-yan Feng Yi Lu jonathan A.Sheps Ren-Xue Wang Jun Han Victor Ling Jian-She Wang The Center for Pediatric Liver Diseases Children’s Hospital of Fudan UniversityShanghaiChina The Department of Pathology Children’s Hospital of Fudan UniversityShanghaiChina BC Cancer Agency VancouverBritish ColumbiaV5Z 1L3Canada University of Victoria-Genome BC Proteomics Center University of VictoriaVictoriaBritish ColumbiaV8Z 7X8Canada Shanghai Key Laboratory of Birth Defects ShanghaiChina

Background and Aims:The aim was to determine if liver biochemistry indices can be used as biomarkers to help differentiate patients with neonatal Dubin–Johnson syndrome(nDJS)from those with biliary atresia(BA).Methods:Patients with genetically-confirmed nDJS or cholangiographically confirmed BA were retrospectively enrolled and randomly assigned to discovery or verification *** liver chemistries,measured during the neonatal period,were *** values were calculated by receiver operating characteristic curve ***:A cohort of 53 nDJS patients was recruited,of whom 13 presented with acholic stools,and 14 underwent diagnostic cholangiography or needle liver biopsy to differentiate from ***-five patients in the cohort,with complete biochemical information measured during the neonatal period,were compared with 133 infants with cholangiographically confirmed *** and direct bilirubin,alanine aminotransferase(ALT),aspartate aminotransferase(AST),total bile acids,alkaline phosphatase,and gamma-glutamyl transferase were significantly lower in nDJS than in *** the discovery cohort,the areas under the curve for ALT and AST were 0.908 and 0.943,*** the validation cohort,13/15 patients in the nDJS group were classified as nDJS,and 10/53 in the BA control group were positive(p<0.00001)with an ALT biomarker cutoff value of 75 IU/*** of 15 patients were classified as nDJS and none were classified positive in the BA group(13/15 vs.0/53,p<0.00001)with an AST cutoff of 87 IU/***:Having assembled and investigated the largest cohort of nDJS patients reported to date,we found that nDJS patients could be distinguished from BA patients using the serum AST level as a *** finding may be clinically useful to spare cholestatic nDJS patients unnecessary invasive procedures.

关键词： Jaundice ABCC2 Cholestasis MRP2 Acholic stools

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Sequential fusion estimation for multisensor systems with non-Gaussian noises

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Science China(Information Sciences) 2020年第12期63卷 153-165页

作者： Liping yan Chenying DI Q.M.jonathan WU Yuanqing XIA Key Laboratory of Intelligent Control and Decision of Complex Systems School of AutomationBeijing Institute of Technology Department of Electrical and Computer Engineering University of Windsor

The sequential fusion estimation for multisensor systems disturbed by non-Gaussian but heavytailed noises is studied in this paper. Based on multivariate t-distribution and the approximate t-filter,the sequential fusion algorithm is presented. The performance of the proposed algorithm is analyzed and compared with the t-filter-based centralized batch fusion and the Gaussian Kalman filter-based optimal centralized fusion. Theoretical analysis and exhaustive experimental analysis show that the proposed algorithm is effective. As the generalization of the classical Gaussian Kalman filter-based optimal sequential fusion algorithm, the presented algorithm is shown to be superior to the Gaussian Kalman filter-based optimal centralized batch fusion and the optimal sequential fusion in estimation of dynamic systems with non-Gaussian noises.

关键词： state estimation sequential fusion non-Gaussian disturbance heavy-tailed noise multivariate $t$-distribution

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Understanding urban structures and crowd dynamics leveraging large-scale vehicle mobility data

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Frontiers of Computer Science 2020年第5期14卷 77-88页

作者： Zhihan Jiang yan Liu Xiaoliang Fan Cheng Wang jonathan Li Longbiao Chen Fujian Key Laboratory of Sensing and Computing for Smart Cities School of Information Science and EngineeringXiamen UniversityXiamen361005China

A comprehensive understanding of city structures and urban dynamics can greatly improve the efficiency and quality of urban planning and management,while the traditional approaches of which,such as manual surveys,usually incur substantial labor and *** this paper,we propose a data-driven framework to sense urban structures and dynamics from large-scale vehicle mobility ***,we divide the city into fine-grained grids,and cluster the grids with similar mobility features into structured urban areas with a proposed distance-constrained clustering algorithm(DCCA).Second,we detect irregular mobility traffic patterns in each area leveraging an ARIMA-based anomaly detection algorithm(ADAM),and correlate them to the urban social and emergency ***,we build a visualization system to demonstrate the urban structures and crowd *** evaluate our framework using real-world datasets collected from Xiamen city,China,and the results show that the proposed framework can sense urban structures and crowd comprehensively and effectively.

关键词： vehicle mobility big data spatial clustering event detection urban computing ubiquitous computing

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