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Effect of Fuzheng Jiedu granule on immunological function and level of immune-related cytokines in immune-suppressed mice

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Journal of Integrative Agriculture 2016年第3期15卷 650-657页

作者： YU Zhan-mei HUANG Xian-hui yan chao-qun GAO Jin LIANG Zi-sen Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation College of Veterinary Medicine South China Agricultural University

Fuzheng Jiedu granule exhibits a number of health benefits and it is thought that the mechanisms involved in these effects are due to the modulation of immunity. In this article, we studied the effect of Fuzheng Jiedu granule on immunological function and the expression of immune-related cytokines in immune-suppressed mice. 72 mice were randomly divided into six groups, with 12 in each group. The control groups included an untreated group, a negative control group（Cyclophosphamide） and a positive control group（Astragalus polysaccharide）. There were three treated groups, which were given different doses of Fuzheng Jiedu granule： a low dose（100 mg kg^（–1））, a medium dose（400 mg kg^（–1）） and a high dose（600 mg kg^（–1））. With the exception of the untreated control animals, each group received an intraperitoneal injection of Cyclophosphamide（100 mg kg^（–1）） for 3 days to establish the immune-suppressed model. Mice were then treated for 19 consecutive days and, 24 h after the last treatment, blood was taken for the eyeballs and serum separation was performed. Analysis was made of the levels of related cytokines（IgA, IgG, IgM, IL-6, IFN-γ, C3, C4 and TNF-α）, the transformation of lymphocytes and the immune organ indexes. The results showed that Fuzheng Jiedu granule can improve the levels of cytokines, the rate of proliferation of lymphocytes and the immune organ indexes of immune-suppressed mice.

关键词： Fuzheng Jiedu granule immune suppression cytokines lymphocytes immune organ index

Energy absorption behaviors of a novel buffer lander-leg with Yoshimura core

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Chinese Journal of Aeronautics 2024年第4期37卷 333-342页

作者： yan XU He HUANG chao ZHANG Rongji FU School of Aeronautics and Astronautics Zhejiang UniversityHangzhou 310027China School of Mechanics Civil Engineering and Architecture Northwestern Polytechnical UniversityXi’an 710072China

In the current soft-landing system,the lander-leg and the buffer are two independent parts which may cause weight *** traditional mechanical buffers also have their own shortcomings such as small buffer stroke and being non-reusable.A Novel Buffer Lander-leg with Yoshimura core (NBLY) is proposed in this paper,inspired by the Buckling Restrained Brace(BRB).The design details of NBLY and parameter definitions of the core are *** finite element analysis modes have been employed to analyze the nonlinear mechanical behaviors of NBLY subjected to the cyclic *** with four different core styles of hexagon,octagon,dodecagon and hexadecagon are analyzed and *** restraining ratio and cumulative dissipation energy ratio have been obtained to evaluate the energy absorption *** results show that the origami pattern has significant influences on the deformation ductility,plastic energy absorbing and axial load transferring to the *** NBLY with octagon core has outstanding properties,especially the hysteretic energy dissipation and enhancement of compression *** interaction mechanism between the core and encasing member constrains the deformation extensions and contributes to the frictional energy dissipation of the *** paper provides a new conceptual design of buffer lander-leg for soft-landing *** can realize the reuse function as a buffer lander-leg with better loading-bearing and energy absorption behaviors.

关键词： Lander-leg structure Origami Energy absorption Cyclic loading Finite element analysis

Structural uncertainty quantification of Reynolds-Averaged Navier–Stokes closures for various shock-wave/boundary layer interaction flows

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Chinese Journal of Aeronautics 2024年第3期37卷 34-48页

作者： Fanzhi ZENG Tianxin ZHANG Denggao TANG Jinping LI chao yan School of Aeronautic Science and Engineering Beihang UniversityBeijing 100191China School of Aeronautical Engineering Air Force Engineering UniversityXi’an 710038China

Accurate prediction of Shock-Wave/Boundary Layer Interaction(SWBLI)flows has been a persistent challenge for linear eddy viscosity models.A major limitation lies in the isotropic representation of the Reynolds stress,as assumed under the Boussinesq *** studies have shown promise in improving the prediction capability for incompressible separation flows by perturbing the Reynolds-stress anisotropy ***,it remains uncertain whether this approach is effective for SWBLI flows,which involve compressibility and *** address this issue,this study systematically quantifies the structural uncertainty of the anisotropy for oblique SWBLI *** eigenspace perturbation method is applied to perturb the anisotropy tensor predicted by the Menter Shear–Stress Transport(SST)model and reveal the impacts of anisotropy on the prediction of quantities of interest,such as separation and reattachment positions,wall static pressure,skin friction,and heat *** results demonstrate the potential and reveal the challenges of eigenspace perturbation in improving the SST ***,a detailed analysis of turbulent characteristics is performed to identify the source of *** findings indicate that eigenspace perturbation primarily affects turbulent shear stress,while the prediction error of the SST model is more related to turbulent kinetic energy.

关键词： Shock-wave/boundary layer interaction(SWBLI) Turbulence models Uncertainty analysis Eigenspace perturbation Anisotropy

A Hybrid Air Quality Prediction Model Based on Empirical Mode Decomposition

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Tsinghua Science and Technology 2024年第1期29卷 99-111页

作者： Yuxuan Cao Difei Zhang Shaoqi Ding Weiyi Zhong chao yan School of Computer Science Qufu Normal UniversityRizhao 276826China School of Mathematical Sciences Qufu Normal UniversityQufu 273165China School of Computer Science Qufu Normal UniversityRizhao 270826China College of Economic and Management Shandong University of Science and TechnologyQingdao 250307China

Air pollution is a severe environmental problem in urban *** air quality prediction can help governments and individuals make proper decisions to cope with potential air *** a classic time series forecasting model,the AutoRegressive Integrated Moving Average(ARIMA)has been widely adopted in air quality ***,because of the volatility of air quality and the lack of additional context information,i.e.,the spatial relationships among monitor stations,traditional ARIMA models suffer from unstable prediction *** some deep networks can achieve higher accuracy,a mass of training data,heavy computing,and time cost are *** this paper,we propose a hybrid model to simultaneously predict seven air pollution indicators from multiple monitoring *** proposed model consists of three components:(1)an extended ARIMA to predict matrix series of multiple air quality indicators from several adjacent monitoring stations;(2)the Empirical Mode Decomposition(EMD)to decompose the air quality time series data into multiple smooth sub-series;and(3)the truncated Singular Value Decomposition(SvD)to compress and denoise the expanded *** results on the public dataset show that our proposed model outperforms the state-of-art air quality forecasting models in both accuracy and time cost.

关键词： air quality prediction Empirical Mode Decomposition(EMD) Singular Value Decomposition(SVD) AutoRegressive Integrated Moving Average(ARIMA)

26-electrons redox-active polyoxovanadate clusters for aqueous zincion batteries

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Nano Research 2024年第5期17卷 4047-4054页

作者： Yimin Xing Wen yan Haiyang Wu Peng Huang chao Wang chao Lai School of Chemistry and Materials Science Jiangsu Normal UniversityXuzhou 221116China

Aqueous zinc-ion batteries(ZIBs)are attaining increasing attention for their high safety and low *** significant progresses in realizing high-performance cathode material for ZIBs,simultaneously endowing them with high capacity and fast-charging capability,the long-term cycling stability remains a major unsolved *** this work,a polyoxovanadate cluster of(NH_(4))_(8)[V_(19)O_(41)(OH)_(9)]·11H_(2)O(NOV)is defined as a cathode material for ZIBs that contains mixed-valence vanadium sites(V^(4+)and V^(5+)).A maximum of 26 electrons can be accommodated in one[V_(19)O_(41)(OH)_(9)]^(8-){V_(19)O_(50)}cluster,contributing to the high theoretical specific capacity of 328 mA·h·g^(-1).The Ti_(3)C_(2)T_(x) MXene nanosheets are incorporated into NOV with the help of ionic liquid(IL)linkers to restrain the dissolution of vanadium species and facilitate electron transport across the *** interfacial bonding,anion exchange,and electrostatic interactions among NOV and MXene are provided by IL *** nanohybrid of NOV-IL-MXene endows excellent contact between MXene and NOV,thereby enhanced charge transfer is observed at ***,the as-synthesized NOV-IL-MXene cathodes exhibit high discharge capacity of 413 mA·h·g^(-1) at 0.2 A·g^(-1) even at high mass loading of 5.2 mg·cm^(-2),remarkable rate performance of 182 mA·h·g^(-1) at 10 A·g^(-1),and impressive cycling stability of 94%capacity retention after 2000 *** work opens up new opportunities to develop advanced polyoxovanadate hybrid cathodes for low-cost and high-performance aqueous ZIBs.

关键词： polyoxovanadate MXene composite materials cathodes zinc-ion batteries

Understanding Discrepancy of Power System Dynamic Security Assessment with Unknown Faults: A Reliable Transfer Learning-based Method

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CSEE Journal of Power and Energy Systems 2024年第1期10卷 427-431页

作者： chao Ren Han Yu yan Xu Zhao yang Dong School of Computer Science and Engineering Nanyang Technological UniversitySingapore School of Electrical and Electronic Engineering Nanyang Technological UniversitySingapore

This letter proposes a reliable transfer learning(RTL)method for pre-fault dynamic security assessment(DSA)in power systems to improve DSA performance in the presence of potentially related unknown *** takes individual discrepancies into consideration and can handle unknown faults with incomplete *** experiment results demonstrate high DSA accuracy and computational efficiency of the proposed RTL *** analysis shows RTL can guarantee system performance.

关键词： Adversarial training dynamic security assessment maximum classifier discrepancy missing data transfer learning

Re-evaluating the nano-sized inorganic protective layer on Cu current collector for anode free lithium metal batteries

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Chinese Chemical Letters 2024年第7期35卷 452-455页

作者： Shuo Zhang Haitao Liao Zhi-qun Liu Chong yan Jia-Qi Huang School of Materials Science&Engineering Beijing Institute of TechnologyBeijing 100081China Advanced Research Institute of Multidisciplinary Science Beijing Institute of TechnologyBeijing 100081China Wuxi Yiwen Microelectronics Technology Co. Ltd.Wuxi 214000China Shanxi Research Institute for Clean Energy Tsinghua UniversityTaiyuan 030032China

Anode free lithium metal batteries(AF-LMBs)have conspicuous advantages both in energy density and the compatibility of battery manufacturing ***,the limited cycle life of AF-LMBs is a crucial factor hindering its practical *** or nitride artificial inorganic solid electrolyte interphase(SEI)has been found as an effective method to prolong the lifespan of ***,by investigating the impact of nano-sized inorganic gradient layers(LiF or Li3N)on initial Li deposition behavior,we notice that the Li^(+) diffusion barrier and the deposition morphology are highly depended on the thickness of inorganic *** protective layers cause larger overpotential as well as more aggregated Li^(+) *** study reveals that the ideal SEI should be synthesized thin and uniformly enough and uncontrollable artificial SEI can cause damage to the lifespan of AF-LMBs.

关键词： Anode free lithium metal battery Solid electrolyte interphase Nano-sized protective layer Lithium fluoride Li deposition behavior

Constructing porous ZnFC-PA/PSF composite spheres for highly efficient Cs^(+) removal

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Journal of Environmental Sciences 2024年第9期143卷 126-137页

作者： Senjian Han chao Gao Wenfeng yan Yafei Guo Shiqiang Wang Tianlong Deng College of Marine and Environmental Sciences Tianjin University of Science and TechnologyTianjin 300457China Key Laboratory of Marine Resource Chemistry and Food Technology Ministry of EducationTianjin 300457China

Radioisotope leaking from nuclear waste has become an intractable problem due to its gamma radiation and strong water *** this work,a novel porous ZnFC-PA/PSF composite sphere was fabricated by immobilization of ferrocyanides modified zinc phytate into polysulfone(PSF)substrate for the treatment of Cs-contaminated *** maximum adsorption capacity of ZnFC-PA/PSF was 305.38 mg/g,and the removal efficiency of Cs+was reached 94.27%within 2 *** ZnFC-PA/PSF presented favorable stability with negligible dissolution loss of Zn^(2+)and Fe^(2+)(<2%).The ZnFC-PA/PSF achieved high-selectivity towards Cs+(K_(d)=2.24×10^(4)mL/g)even in actual geothermal *** adsorption mechanism was inferred to be the ion-exchange between Cs^(+)and K^(+).What’s more,ZnFC-PA/PSF worked well in the fixed-bed adsorption(E=91.92%),indicating the application potential for the hazardous Cs^(+)removal from wastewater.

关键词： Adsorption Cesium Metal ferrocyanide Composite adsorbent

Warhead fragments motion trajectories tracking and spatio-temporal distribution reconstruction method based on high-speed stereo photography

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Defence Technology（防务技术） 2024年第7期37卷 162-172页

作者： Pengyu Hu Jiangpeng Wu Zhengang yan Meng He chao Liang Hao Bai Xi'an Modern Control Technology Research Institute Xi'an710065China Xi'an OET Science and Technology Co. LtdXi'an710076China

High speed photography technique is potentially the most effective way to measure the motion parameter of warhead fragment benefiting from its advantages of high accuracy,high resolution and high ***,it faces challenge in dense objects tracking and 3D trajectories reconstruction due to the characteristics of small size and dense distribution of fragment *** address these challenges,this work presents a warhead fragments motion trajectories tracking and spatio-temporal distribution reconstruction method based on high-speed stereo ***,background difference algorithm is utilized to extract the center and area of each fragment in the image ***,a multi-object tracking(MOT)algorithm using Kalman filtering and Hungarian optimal assignment is developed to realize real-time and robust trajectories tracking of fragment *** reconstruct 3D motion trajectories,a global stereo trajectories matching strategy is presented,which takes advantages of epipolar constraint and continuity constraint to correctly retrieve stereo correspondence followed by 3D trajectories refinement using polynomial ***,the simulation and experimental results demonstrate that the proposed method can accurately track the motion trajectories and reconstruct the spatio-temporal distribution of 1.0×10~3fragments in a field of view(FOV)of 3.2 m×2.5 m,and the accuracy of the velocity estimation can achieve 98.6%.

关键词： Warhead fragment measurement High speed photography Stereo vision Multi-object tracking Spatio-temporal reconstruction