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Language of plants: Where is the word?

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Journal of Integrative Plant Biology 2016年第4期58卷 343-349页

作者： Maja impraga Junji takabayashi Jarmo K.Holopainen Botanical Garden Faculty of Science Ghent University Department of Environmental Science University of Eastern Finland Center for Ecological Research Kyoto University

Plants emit biogenic volatile organic compounds（BVOCs） causing transcriptomic, metabolomic and behavioral responses in receiver organisms. Volatiles involved in such responses are often called ＂plant language＂. Arthropods having sensitive chemoreceptors can recognize language released by plants. Insect herbivores, pollinators and natural enemies respond to composition of volatiles from plants with specialized receptors responding to different types of compounds. In contrast, the mechanism of how plants＂hear＂ volatiles has remained obscured. In a plant-plant communication, several individually emitted compounds are known to prime defense response in receiver plants with a specific manner according to the chemical structure of each volatile compound. Further, composition and ratio of volatile compounds in the plant-released plume is important in plantinsect and plant-plant interactions mediated by plant volatiles. Studies on volatile-mediated plant-plant signaling indicate that the signaling distances are rather short, usually not longer than one meter. Volatile communication from plants to insects such as pollinators could be across distances of hundreds of meters. As many of the herbivore induced VOCs have rather short atmospheric life times, we suggest that in long-distant communications with plant volatiles,reaction products in the original emitted compounds may have additional information value of the distance to emission source together with the original plant-emitted compounds.

关键词： Green leaf volatiles plant-insect communication plant language semiochemicals volatiles

Free Energy Change of Micelle Formation for Sodium Dodecyl Sulfate from a Dispersed State in Solution to Complete Micelles along Its Aggregation Pathways Evaluated by Chemical Species Model Combined with Molecular Dynamics Calculations

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物理化学学报 2018年第10期34卷 1163-1170页

作者： yOSHII Noriyuki KOMORI Mika KAWADA Shinji takabayashi Hiroaki FUJIMOTO Kazushi OKAZAKI Susumu Center for Computational Science Graduate School of EngineeringNagoya UniversityNagoya 464-8603Japan Department of Applied Chemistry Nagoya UniversityNagoya 464-8603Japan

Surfactant molecules, when dispersed in solution, have been shown to spontaneously form aggregates. Our previous studies on molecular dynamics(MD) calculations have shown that ionic sodium dodecyl sulfate molecules quickly aggregated even when the aggregation number is small. The aggregation rate, however, decreased for larger aggregation numbers. In addition, studies have shown that micelle formation was not completed even after a 100 ns-long MD run(Chem. Phys. Lett. 2016, 646, 36). Herein, we analyze the free energy change of micelle formation based on chemical species model combined with molecular dynamics calculations. First, the free energy landscape of the aggregation, ?G_(i+j)^+, where two aggregates with sizes i and j associate to form the(i + j)-mer, was investigated using the free energy of micelle formation of the i-mer, G_i^+, which was obtained through MD calculations. The calculated ?G_(i+j)^+ was negative for all the aggregations where the sum of DS ions in the two aggregates was 60 or less. From the viewpoint of chemical equilibrium, aggregation to the stable micelle is desired. Further, the free energy profile along possible aggregation pathways was investigated, starting from small aggregates and ending with the complete thermodynamically stable micelles in solution. The free energy profiles, G(l, k), of the aggregates at l-th aggregation path and k-th state were evaluated by the formation free energy ∑_in_i( l,k)G_i^+ and the free energy of mixing ∑_in_i( l,k)k_BTln( n_i( l,k)/n( l,k)), where ni(l, k) is the number of i-mer in the system at the l-th i aggregation path and k-th state, with n(l,k)= ∑_n_i( l,k). All the aggregation pathways were obtained from the initial i state of 12 pentamers to the stable micelle with i = 60. All the calculated G(l, k) values monotonically decreased with increasing k. This indicates that there are no free energy barriers along the pathways. Hence, the slowdown is not due to the thermodynamic stability of the aggre

关键词： Free energy change Aggregation pathway SDS Micelle Molecular dynamics calculation

Development of PC Worker’s Management System in PC Training Room and Office by Using IoT Technology

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Journal of Electrical Engineering 2018年第4期6卷 221-228页

作者： Keiichi Abe yuki takabayashi Masao Isshiki Kanagawa Institute of Technology Atsugi City Kanagawa 243-0292 Japan

At present time, there has been a demand for management systems that can survey and monitor a PC （personal computer） practice room, movement of people in an office, situation of utilization of facilities and so on in real time without causing psychological stress. For example, PC administrators in Japanese national educational institutions must report operation status of PC practice rooms once a year. But, there is currently no system for automatically recording PC operating situations. Therefore, the burden on the PC administrators is big. In this study, we aimed at systems for accurately managing the sitting and work time without psychologically stressing PC users. This time, we propose uniform management systems of sitting and work time using smart tap node and mat sensor node by IoT （Internet of Things） technology. The smart tap was connected to PCs to acquire the operating status of the PCs. In parallel with this smart tap, the mat sensor was used to acquire human presence state. By calculating binary data representing the PC operating status and human presence state from the two sensing data （smart tap and mat sensor） by the proposed technique, we can exactly calculate wasteful power consumption etc. The use of IoT technology makes it unnecessary to use large installation services when introducing our system. Therefore, this our proposal system can be easily installed even by unskilled workers.

关键词： PC worker’s management system smart tap node mat sensor node IoT technology sensor network.

Phase Ⅱ study of protracted irinotecan infusion and a low-dose cisplatin for metastatic gastric cancer

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World Journal of Gastroenterology 2006年第40期12卷 6522-6526页

作者： Hiroshi Imamura Masataka Ikeda Hiroshi Furukawa Toshimasa Tsujinaka Kazumasa Fujitani Kenji Kobayashi Hiroyuki Narahara Michio Kato Haruhiko Imamoto Arimichi takabayashi Hideaki Tsukuma Department of Surgery Sakai Municipal Hospital Osaka Japan Department of Surgery Osaka National Hospital Osaka Japan Department of Surgery Kinki Central Hospital Hyogo Japan Department of Internal Medicine Osaka Medical Center for Cancer and Cardiovascular Diseases Osaka Japan Department of Surgery Kinki University School of Medicine Osaka Japan Department of Surgery Kansai Rosai Hospital Hyogo Japan Department of Surgery Kitano Hospital & Research Institute Osaka Japan

AIM: To test protracted irinotecan infusion plus a low-dose cisplatin in this Phase Ⅱ trial to decrease its toxic-ity. METHODS: The eligibility criteria were: (1) histologi-cally proven measurable gastric cancer; (2) performance status of 0 or 1; (3) no prior chemotherapy or comple-tion of prior therapy at least 4 wk before enrollment; (4) adequate function of major organs; (5) no other active malignancy; and (6) written informed consent. The regi-men consisted of irinotecan (60 mg/m2) on d 1 and 15 by 24-h infusion and cisplatin (10 mg/m2) on d 1, 2, 3, 15, 16, and 17. Treatment was repeated every 4 wk. RESULTS: Thirty-one patients were registered between April 2000 and January 2001. The response rate for all 31 patients, 20 patients without prior chemotherapy, and 11 patients with prior chemotherapy was 52% (16/31), 60% (12/20), and 36% (4/11), respectively. The median survival time was 378 d. The median number of courses given to all patients was 2. Grade 4 neutropenia oc-curred in 11 (35%) patients, while grade 3 to 4 diarrhea or nausea occurred in 1 (3%) and 3 (10%) patients, respectively. Fatigue was minimal as grade 1 fatigue was found only in 3 (10%) patients. Other adverse events were mild and no treatment-related deaths ***: This regimen showed a high level of ac-tivity and acceptable toxicity in patients with metastatic gastric cancer.

关键词： Gastric cancer CPT-11 CDDP Protracted Irinotecan Chemotherapy

Double balloon enteroscopy to retrieve an accidentally swallowed dental reamer deep in the jejunum

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World Journal of Gastrointestinal Endoscopy 2011年第4期3卷 78-80页

作者： Shingo Kato Kazuhito Kani Hidehiko takabayashi Ryuichi yamamoto Koji yakabi Department of Gastroenterology and Hepatology Saitama Medical CenterSaitama Medical UniversityKawagoe CitySaitama 350-8550Japan

Accidentally swallowed foreign objects are not uncommon but difficult to manage without complications. We describe the case of a 68 year old man who accidentally a swallowed sharp-pointed dental reamer that had reached deep in his jejunum. Double balloon enteroscopic retrieval was performed with polypectomy snare but the reamer was entangled in the wire loop of the snare and penetrated the jejunal wall. After releasing the reamer by pushing and pulling the snare for approximately 30 min, the reamer was retrieved with biopsy forceps. This is the first report of double balloon enteroscopic removal of a dental reamer. Furthermore, this is a novel case with regard to decision making in situations when sharp objects are swallowed.

关键词： Dental reamer Jejunum Double balloon enteroscopy Endoscopic retrieval of sharp objects

Variables associated with suicide ideation and plans in a Japanese population

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Health 2011年第5期3卷 276-287页

作者： Takuya Hasegawa Chiyoe Murata Tatsuya Noda Tomoko takabayashi Takashi Ninomiya Shinya Hayasaka Toshiyuki Ojima 不详

The purpose of our study was to clarify variables associated with suicide ideation and plans in a Japanese population. We conducted a random-sampling survey on mental health and suicide using a self-administered questionnaire for Hamamatsu City residents aged 15-79 yrs between May and June, 2008. This included questions about gender, age, outpatient treatment, alcohol problems, depression, living ar-rangements, marital status, annual family income, industry types as well as suicide ideation and plans. The correlation between these variables and suicide ideation or plans was then analyzed with multiple logistic regression analysis by gender. A total of 1051 responded to this questionnaire (response rate, 53.9%). Variables statistically associated with suicide ideation in males included alcohol problems, depression, lower annual family income, and ac-commodations/eating/drinking services, while in females, the variables were younger age, outpatient treatment, depression, living alone, being single, being separated, lower annual family income, accommodations/eating/drinking services and unemployment. On the other hand, variables statistically associated with suicide plans in males were younger age, alcohol problems, depression, and lower annual family income, while in females they were younger age, alcohol problems, depression, being separated, lower annual family income, manufacturing, and accommodations/eating/drinking services. Ex-cept for industry types, variables associated with suicide ideation or plans were consistent with previous studies. The reason why workers engaging in manufacturing, or accommoda-tions/eating/drinking services were more likely to have suicide ideation or plans may be attributed to the structures and/or stresses unique to those industries.

关键词： Suicide Ideation Suicide Plans Variables

日本制丝技术的变迁与传承——冈谷蚕丝博物馆的建设与努力

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丝绸 2019年第10期56卷 21-26页

作者：高林千幸费万春冈谷蚕丝博物馆

文章从冈谷蚕丝博物馆的建设出发,分别介绍了日本制丝技术的发展历程、制丝技术的传承,以及与苏州丝绸博物馆的交流,展示了日本缫丝机的变化发展,也体现了日本冈谷蚕丝博物馆与中国苏州丝绸博物馆之间关于古代复原丝绸文化的交流与合作。

关键词：日本制丝技术蚕丝博物馆缫丝机交流

Wafer-level hermetically sealed silicon photonic MEMS

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Photonics Research 2022年第2期10卷 I0001-I0008页

作者： Gaehun Jo Pierre Edinger Simon J.Bleiker Xiacxjing Wang Alain yuji takabayashi Hamed Sattari Niels Quack Moises Jezzini Jun Su Lee Peter Verheyen Iman Zand Umar Khan Wim Bogaerts Göran Stemme Kristinn B.Gylfason Frank Niklaus Division of Micro and Nanosystems KTH Royal Institute of Technology11428 StockholmSweden École Polytechnique Federate de Lausanne(EPFL) 1015 LausanneSwitzerland Tyndall National Institute Lee Maltings Complex Dyke ParadeT12 R5CP CorkIreland imec vzw.3DSIP Department Si Photonics GroupKapeldreef 753001 LeuvenBelgium Department of Information Technology Photonics Research GroupGhent University-IMEC9052 GentBelgium

The emerging fields of silicon(Si) photonic micro–electromechanical systems(MEMS) and optomechanics enable a wide range of novel high-performance photonic devices with ultra-low power consumption, such as integrated optical MEMS phase shifters, tunable couplers, switches, and optomechanical resonators. In contrast to conventional SiO;-clad Si photonics, photonic MEMS and optomechanics have suspended and movable parts that need to be protected from environmental influence and contamination during operation. Wafer-level hermetic sealing can be a cost-efficient solution, but Si photonic MEMS that are hermetically sealed inside cavities with optical and electrical feedthroughs have not been demonstrated to date, to our knowledge. Here, we demonstrate wafer-level vacuum sealing of Si photonic MEMS inside cavities with ultra-thin caps featuring optical and electrical feedthroughs that connect the photonic MEMS on the inside to optical grating couplers and electrical bond pads on the outside. We used Si photonic MEMS devices built on foundry wafers from the iSiPP50G Si photonics platform of IMEC, Belgium. Vacuum confinement inside the sealed cavities was confirmed by an observed increase of the cutoff frequency of the electro-mechanical response of the encapsulated photonic MEMS phase shifters, due to reduction of air damping. The sealing caps are extremely thin, have a small footprint, and are compatible with subsequent flip-chip bonding onto interposers or printed circuit boards. Thus, our approach for sealing of integrated Si photonic MEMS clears a significant hurdle for their application in high-performance Si photonic circuits.

关键词： sealed sealing bonding

Endoscopic characteristics of small intestinal malignant tumors observed by balloon-assisted enteroscopy

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World Journal of Gastrointestinal Endoscopy 2019年第5期11卷 373-382页

作者： Tomofumi Horie Naoki Hosoe Kaoru takabayashi yukie Hayashi Kenji JL Limpias Kamiya Ryoichi Miyanaga Shinta Mizuno Kayoko Fukuhara Seiichiro Fukuhara Makoto Naganuma Masayuki Shimoda Haruhiko Ogata Takanori Kanai Division of Gastroenterology and Hepatology Department of Internal MedicineSchool of MedicineKeio University Center for Diagnostic and Therapeutic Endoscopy School of MedicineKeio University Department of Pathology School of MedicineKeio University

BACKGROUND Capsule endoscopy and balloon-assisted enteroscopy(BAE) enable visualization of rare small bowel conditions such as small intestinal malignant ***,details of the endoscopic characteristics of small intestinal malignant tumors are still *** To elucidate the endoscopic characteristics of small intestinal malignant *** From March 2005 to February 2017,1329 BAE procedures were performed at Keio University Hospital. Of these procedures,malignant tumors were classified into three groups,Group 1: epithelial tumors including primary small intestinal cancer,metastatic small intestinal cancer,and direct small intestinal invasion by an adjacent organ cancer; Group 2: small intestinal malignant lymphoma; and Group 3,small intestinal gastrointestinal stromal tumors. We systematically collected clinical and endoscopic data from patients' medical records to determine the endoscopic characteristics for each *** The number of patients in each group was 16(Group 1),23(Group 2),and 6(Group 3),and the percentage of solitary tumors was 100%,43.5%,and 100%,respectively(P ymptoms,and laboratory data were not significantly different between the groups. Seventy-five percent of epithelial tumors(Group 1) were located in the upper small intestine(duodenum and ileum),and approximately 70% of gastrointestinal stromal tumors(Group 3) were located in the jejunum. Solitary protruding or mass-type tumors were not seen in malignant lymphoma(Group2)(P y; P = 0.004). Enlarged white villi inside and/or surrounding the tumor were seen in 12.5%,54.5%,and 0% in Group 1,2,and 3,respectively(P = 0.001).CONCLUSION The differential diagnosis of small intestinal malignant tumors could be tentatively made based on BAE findings.

关键词： Small intestine Malignant Tumor Double balloon enteroscopy Balloon enteroscopy Video capsule endoscopy Endoscopy