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Neural Regeneration Research 2021年第12期16卷 2403-2404页

作者： Dawn G.L.Thean Alan s.L.wong Laboratory of Combinatorial Genetics and synthetic Biology School of Biomedical SciencesThe University of Hong KongPokfulamHong Kong Special Administrative RegionChina Department of Electrical and Electronic Engineering The University of Hong KongPokfulamHong Kong Special Administrative RegionChina

Diving into the search for effective cell differentiation factors:Researchers are still striving to find better therapeutics to revert or slow down the progression of neurological disorders such as Parkinson’s disease,Alzheimer’s disease,and Huntington’s *** disorders are the result of neuronal cell death in different parts of the *** or treatments used to relieve the symptoms in patients have not been well *** do not recover the damaged neural tissues and can result in unwanted side effects.

关键词： Huntington neural Alzheimer

How to evaluate diagnosis and management of biliary atresia in the era of liver Transplantation in China

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World Journal of Pediatric surgery 2018年第1期1卷 3-8页

作者： Jianghua Zhan yajun Chen Kenneth K y wong Department of Pediatric surgery Tianjin Children’s HospitalTianjinChina Department of Pediatric surgery Beijing Children’s HospitalBeijingChina Department of Pediatric surgery Queen Mary HospitalHong KongChina

background Biliary atresia(BA)is one of the most challenging hepatobiliary diseases in *** the reasonable outcome of liver transplantation(LT),portoenteral anastomosis(Kasai operation)is still the first choice of treatment for patients with *** to improve the survival rate of the patients with BA in the era of LT is a new *** sources Based on recent original publications and the experience with the BA in China,we review many factors that influence BA survival situation,including early diagnosis and screen plan,defects of early treatment,Kasai operation,and LT and indicate present questions about BA diagnosis and treatment in *** BA diagnosis may also be delayed due to insufficient understanding of BA and lack of jaundice monitoring methods at different levels of the hospitals in *** education of the physicians at smaller city hospitals about BA,neonatal jaundice and cholestasis would be helpful in improving early diagnosis of *** surgical intervention is still the only guarantee to improve the survival rate of BA with native *** In the era of LT,especially in China,Kasai operation can provide waiting time for living donor LT and improve the success rate of LT and minimize the rapid deterioration of liver function of the children with BA and decrease the mortality in patients with BA.

关键词： diagnosis treatment guarantee

Multi-place physics and multi-place nonlocal systems

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Communications in Theoretical Physics 2020年第5期72卷 120-132页

作者： s y Lou school of Physical science and Technology Ningbo UniversityNingbo315211China

Multi-place nonlocal systems have attracted attention from many *** this paper,we mainly review the recent progresses on two-place nonlocal systems(Alice-Bob systems)and four-place nonlocal ***-place systems can firstly be derived from many physical problems by using a multiple scaling method with a discrete symmetry group including parity,time reversal,charge conjugates,rotations,field reversal and exchange *** nonlocal systems can also be derived from the symmetry reductions of coupled nonlinear systems via discrete symmetry *** the other hand,to solve multi-place nonlocal systems,one can use the symmetry-antisymmetry separation approach related to a suitable discrete symmetry group,such that the separated systems are coupled local *** using the separation method,all the known powerful methods used in local systems can be applied to nonlocal *** this review article,we take two-place and four-place nonlocal nonlinear schr?dinger(NLs)systems and Kadomtsev-Petviashvili(KP)equations as simple examples to explain how to derive and solve *** types of novel physical and mathematical points related to the nonlocal systems are especially emphasized.

关键词： multi-place physics multi-place nonlocal systems symmetries integrable systems parity and time reversal soliton theory classical prohibitions

香港特别行政区视障读者服务创新探究——以香港城市大学邵逸夫图书馆高等融合教育支持服务为例

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国家图书馆学刊 2024年第2期33卷 74-82页

作者：景祥祜王玮乐肖寒月香港城市大学邵逸夫图书馆中国香港城市大学中国

图书馆是高校教育的第二课堂,融合教育可以应用两阶段服务学习创新模式,来优化视障大学生的高等融合教育体验。香港城市大学“灯塔古迹保育研习实践项目”践行融合教育理念,邀请视障和健视大学生以灯塔共同创作出4项典型项目成果。其中... 详细信息

图书馆是高校教育的第二课堂,融合教育可以应用两阶段服务学习创新模式,来优化视障大学生的高等融合教育体验。香港城市大学“灯塔古迹保育研习实践项目”践行融合教育理念,邀请视障和健视大学生以灯塔共同创作出4项典型项目成果。其中《西屿塔灯历险》案例具体展示了两阶段服务学习的开展方式,探究图书馆在高等融合教育支持服务体系下的视障读者服务创新。图3。表1。参考文献22。

关键词：高等融合教育服务学习视障读者高等教育信息素养框架

Ophthalmology in the time of COVID-19: experience from Hong Kong Eye Hospital

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International Journal of Ophthalmology(English edition) 2020年第6期13卷 851-859页

作者： stephanie s.L.Cheung Cherie y.K.wong Jason C.K.Chan Carmen K.M.Chan N.M.Lam Hunter K.L.yuen Victoria W.y.wong Chi Wai Tsang Clement C.y.Tham Department of Ophthalmology and Visual sciences the Chinese University of Hong KongHong Kong SARChina Hong Kong Eye Hospital Hong Kong SARChina

AIM:To review international guidelines and to share our infection control experience during the coronavirus disease 2019(COVID-19)pandemic at a tertiary eye centre in Hong ***:Infection control guidelines and recommendations from international ophthalmological bodies are reviewed and *** measures at our hospital were drawn up as per international and local health authorities’guidelines and implemented with the collaboration of doctors,nurses and administrative ***:The aims of our infection control measures are to 1)minimize cross-infection within the hospital;2)protect and support hospital staff;3)ensure environmental *** minimize the risk of cross-infection,outpatient attendance and elective surgery have been reduced by 40%,and general anesthesia procedures were reduced by 90%.Patients entering the hospital are screened for fever,travel history,contact and cluster history,and COVID-19 related *** protect and support hospital staff,we ensure provision of adequate personal protective equipment(PPE)and provide clear guidelines on the level of PPE needed,depending on the clinical *** protective measures include provision of work uniforms,easy access to alcohol-based hand rub,opening new lunch areas,implementation of self-monitoring and self-reporting systems,and communication via online education and ***,environmental control is achieved by ensuring regular disinfection of the hospital premise,enhancing ventilation,and usage of disposable ophthalmic ***:Our multi-pronged approach to infection control is,so far,successful in minimizing infection risks,while allowing the maintenance of essential ophthalmic services.

关键词： COVID-19 coronavirus sARs-CoV-2 ophthalmology infection control Hong Kong

Pharmacological approach to restoring steroid sensitivity in respiratory diseases

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中国药理学与毒理学杂志 2018年第4期32卷 242-243页

作者： W.s. Fred wong Department of Pharmacology Yong Loo Lin School of Medicine National University Health System 117600 Singapore Immunology Program Life Science Institute National University of Singapore 117456 Singapore singapore-HUJ Alliance for Research a

Inhaled corticosteroid is the first-line controller for asthma and ***,about 10% of the asthmatics(severe/refractory asthma) and most of the COPD patients are resistant to the beneficial effects of *** is a pressing unmet medical need to develop novel therapeutic agents to restore corticosteroid efficacy in affected *** have been reports showing the promise of theophylline and rapamycin in reversing steroid resistance in *** laboratory has demonstrated that andrographolide,a bioactive diterpenoid lactone isolated from the plant Andrographis paniculata,is an effective anti-inflammatory and anti-oxidative compound in both asthma and COPD experimental *** a severe asthma mouse model using combined IFN-γ/LPs exposure,production of IL-27 and methacholine-induced airway hyperresponsiveness(AHR) were found to be *** was found to restore the anti-inflammatory effect of dexamethasone in LPs/IFN-γ-induced IL-27 levels in bronchoalveolar lavage(BAL) fluid and AHR in ***/IFN-γ markedly reduced the nuclear level of histone deacetylase-2(HDAC2),an essential epigenetic enzyme that mediates corticosteroid anti-inflammatory *** significantly restored nuclear HDAC2 levels and diminished total HAT/HDAC activity ratio in mouse lungs exposed to LPs/IFN-γ,probably via suppression of PI3K/Akt/HDAC2 phosphorylation and up-regulation of the antioxidant transcription factor Nrf2 *** a cigarette smoke(Cs)-induced COPD model,andrographolide markedly restored dexamethasone actions in inhibiting Cs-induced lung *** addition,andrographolide facilitated dexamethasone actions to suppress BAL fluid IL-6,IL-1b,KC and IL-17 *** lung lysates,andrographolide markedly restored total nuclear HDAC *** complete steroid re-sensitization mechanism of andrographolide remains to be ***,our existing data strongly implicate a potentially novel steroid re

关键词：皮质类固醇治疗方法药物治疗哮喘

On the question of quark confinement in the Abelian U(1)QED gauge interaction

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Frontiers of physics 2023年第6期18卷 39-91页

作者： Cheuk-yin wong Physics Division Oak Ridge National Laboratory*Oak RidgeTN 37831USA

If we approximate light quarks as massless and apply the schwinger confinement mechanism to light quarks,we will reach the conclusion that a light quark and its antiquark will be confined as a boson in the Abelian U(1)QED gauge interaction in(1+1)D,as in an open *** the work of Coleman,Jackiw,and susskind,we can infer further that the schwinger confinement mechanism persists even for massive quarks in(1+1)*** such a QED-confined one-dimensional open string in(1+1)D be the idealization of a flux tube in the physical world in(3+1)D,similar to the case of QCD-confined open string?If so,the QED-confined bosons may show up as neutral QED mesons in the mass region of many tens of MeV[***.C 81,064903(2010)&*** Energy Phys.2020(8),165(2020)].Is it ever possible that a quark and an antiquark be produced and interact in QED alone to form a confined QED meson?Is there any experimental evidence for the existence of a QED meson(or QED mesons)?The observations of the anomalous soft photons,the X17 particle,and the E38 particle suggest that they may bear the experimental evidence for the existence of such QED *** confirmation and investigations on the X17 and E38 particles will shed definitive light on the question of quark confinement in QED in(3+1)*** of quark confinement in the QED interaction are discussed.

关键词： quark confinement QCD interaction QED interaction schwinger model open string model of mesons QCD molecular states

Magnetic field regression using artificial neural networks for cold atom experiments

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Chinese Physics B 2024年第2期33卷 46-51页

作者：陈子霆黃建陶 Bojeong seo 黄明琛 Mithilesh K.Parit 何逸飞甄浩廷 Jensen Li Gyu-Boong Jo Department of Physics The Hong Kong University of Science and TechnologyKowloon 999077China

Accurately measuring magnetic fields is essential for magnetic-field sensitive experiments in areas like atomic,molecular,and optical physics,condensed matter experiments,and other ***,since many experiments are often conducted in an isolated environment that is inaccessible to experimentalists,it can be challenging to accurately determine the magnetic field at the target ***,we propose an efficient method for detecting magnetic fields with the assistance of an artificial neural network(NN).Instead of measuring the magnetic field directly at the desired location,we detect fields at several surrounding positions,and a trained NN can accurately predict the magnetic field at the target *** training,we achieve a below 0.3%relative prediction error of magnetic field magnitude at the center of the vacuum chamber,and successfully apply this method to our erbium quantum gas apparatus for accurate calibration of magnetic field and long-term monitoring of environmental stray magnetic *** demonstrated approach significantly simplifies the process of determining magnetic fields in isolated environments and can be applied to various research fields across a wide range of magnetic field magnitudes.

关键词： ultracold gases trapped gases measurement methods and instrumentation

Predicting air pressure in drainage stack of high-rise building

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Applied Mathematics and Mechanics(English Edition) 2013年第3期34卷 351-362页

作者： E. s. W. wong 李应林朱祚金 Industrial Center The Hong Kong Polytechnic University school of Engineering science University of Science and Technology of China

It is necessary to understand the features of air pressure in a drainage stack of a high-rise building for properly designing and operating a drainage system. This paper presents a mathematical model for predicting the stack performance. A step function is used to describe the effect of the air entrainment caused by the water discharged from branch pipes. An additional source term is introduced to reflect the gas-liquid interphase interaction （GLII） and stack base effect. The drainage stack is divided into upper and base parts. The air pressure in the upper part is predicted by a total variation diminishing （TVD） scheme, while in the base part, it is predicted by a characteristic line method （CLM）. The predicted results are compared with the data measured in a real-scale high- rise test building. It is found that the additional source term in the present model is effective. It intensively influences the air pressure distribution in the stack. The air pressure is also sensitive to the velocity-adjusting parameter （VAP）, the branch pipe air entrainment, and the conditions on the stack bottom.

关键词： air pressure in drainage stack characteristic line method stack base effect,interphase interaction

RF channel performance assessment for a multiple carrier millimeter-wave communication system

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Progress in Natural science:Materials International 2004年第10期14卷 45-48页

作者： Thomas wong Chicago Department of Electrical and Computer Engineering Illinois Institute of Technology Illinois60616 U.s.A

Channel capacity,system versatility and ease of maintenance are factors of prime concern in future generations of wire-less communication *** a result,millimeter-wave can offer considerable advantages in providing broadband *** and noise effects,including parametric fluctuations,are two significant causes for signal degradation in broadband communication *** methods to assess the performance of an RF channel in a multi-carrier system are *** measuring the forward transfer func-tion from transmitter IF to receiver IF as the frequency is swept across the channel bandwidth,characteristics such as gain flatness,chan-nel dispersion,and saturation effects are *** evaluate the ability of the communication link in preserving the synchronization be-tween two carriers,their heterodyned spectrum at the receiver IF output is *** measurement methods employ standard equip-ment and have been found to be effective when applied to a multi-carrier millimeter-wave system with over1GHz instantaneous band-width.

关键词： millimeter-wave communication system multiple carrier intermodulation carrier fluctuation synchronization