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轻度认识损害与Alzheimer病抽象推理能力衰退:通过指数化李代数分析获得的微分同胚解剖定位发现局部灰质容积减小的相关性研究

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国际医学放射学杂志 2011年第2期 203-204页

作者： T.yoshiura A.Hiwatashi K.yamashita y.Ohyagi A.Monji y.takayama 唐光健 Department of Clinical Radiology Graduate School of Medical SciencesKyushu University

目的通过痴呆病人皮质Raven逐渐着色基质(CPM)测量确定抽象推理能力衰退的相关脑区域。方法回顾性分析37例连续病人,包括19例Alzheimer病(AD)与18

关键词： MRI 脑痴呆 Alzheimer病轻度认识损害

Algorithm Selection Method Based on Coupling Strength for Partitioned Analysis of Structure-Piezoelectric-Circuit Coupling

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1237-1258页

作者： Daisuke Ishihara Naoto takayama Department of Intelligent and Control Systems Kyushu Institute of TechnologyIizuka820-8502Japan

In this study, we propose an algorithm selection method based on coupling strength for the partitioned analysis ofstructure-piezoelectric-circuit coupling, which includes two types of coupling or inverse and direct piezoelectriccoupling and direct piezoelectric and circuit coupling. In the proposed method, implicit and explicit formulationsare used for strong and weak coupling, respectively. Three feasible partitioned algorithms are generated, namely(1) a strongly coupled algorithm that uses a fully implicit formulation for both types of coupling, (2) a weaklycoupled algorithm that uses a fully explicit formulation for both types of coupling, and (3) a partially stronglycoupled and partially weakly coupled algorithm that uses an implicit formulation and an explicit formulation forthe two types of coupling, *** examples using a piezoelectric energy harvester,which is a typicalstructure-piezoelectric-circuit coupling problem, demonstrate that the proposed method selects the most costeffectivealgorithm.

关键词： Multiphysics coupling strength partitioned algorithm structure-piezoelectric-circuit coupling strongly coupled algorithm weakly coupled algorithm

Hybrid Strategy of Partitioned and Monolithic Methods for Solving Strongly Coupled Analysis of Inverse and Direct Piezoelectric and Circuit Coupling

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1371-1386页

作者： Daisuke Ishihara Syunnosuke Nozaki Tomoya Niho Naoto takayama Department of Intelligent and Control Systems Kyushu Institute of TechnologyFukuokaJapan

The inverse and direct piezoelectric and circuit coupling are widely observed in advanced electro-mechanical systems such as piezoelectric energy *** strongly coupled analysis methods based on direct numerical modeling for this phenomenon can be classified into partitioned or monolithic *** formulation has its advantages and disadvantages,and the choice depends on the characteristics of each coupled *** study proposes a new option:a coupled analysis strategy that combines the best features of the existing formulations,namely,the hybrid partitioned-monolithic *** analysis of inverse piezoelectricity and the monolithic analysis of direct piezoelectric and circuit interaction are strongly coupled using a partitioned iterative hierarchical *** a typical benchmark problem of a piezoelectric energy harvester,this research compares the results from the proposed method to those from the conventional strongly coupled partitioned iterative method,discussing the accuracy,stability,and computational *** proposed hybrid concept is effective for coupled multi-physics problems,including various coupling conditions.

关键词： Structure-piezoelectric-circuit interaction energy harvesting partitioned method monolithic method hybrid method

MRI酰胺质子转移成像与子宫内膜样腺癌组织学分级的关系

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国际医学放射学杂志 2018年第3期 344-344页

作者： y.takayama A.Nishie O.Togao y.Asayama K.Ishigami y.Ushijima 吕晓虹 Department of Clinical Radiology Graduate School of Medical Sciences Kyushu University

摘要目的评估酰胺质子转移(APT)成像在子宫内膜样腺癌(EEA)组织学分级中的效用。材料与方法本前瞻性研究经机构伦理委员会批准。纳入2012年6月—2016年3

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肿块型肝内胆管细胞癌:动态增强CT动脉期强化方式与临床病理结果的相关性研究

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国际医学放射学杂志 2017年第2期 236-236页

作者： N.Fujita y.Asayama A.Nishie K.Ishigami y.Ushijima y.takayama 徐飞 Department of Clinical Radiology Graduate School of Medical SciencesKyushu University

摘要目的评估肝内胆管细胞癌(ICC)在动态CT增强动脉期(HAP)强化方式与临床病理表现(尤其是门周型和周围型)的相关性。方法入组47例病理证实的ICC病人。根据

关键词：胆管细胞癌动脉期强化方式临床病理肝内 CT

增强后CT值在肝外胆管细胞癌中预后意义的研究

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国际医学放射学杂志 2017年第4期 494-494页

作者： y.Asayama A.Nishie K.Ishigami y.Ushijima y.takayama D.Okamoto 朱珍 Department of Advanced Imaging and Interventional Radiology Graduate School of Medical Sciences Kyushu University

摘要目的研究动态增强CT的廓清效应能否预测肝外胆管细胞癌(EHC)病人的生存期。方法本研究共收集46例手术切除的病人。所有病例均行多层螺旋CT动态增强检查。兴趣区(ROI)选择肿瘤的平扫、静脉期和延迟期并用以下方法计算廓清率:[(静脉...

摘要目的研究动态增强CT的廓清效应能否预测肝外胆管细胞癌(EHC)病人的生存期。方法本研究共收集46例手术切除的病人。所有病例均行多层螺旋CT动态增强检查。兴趣区(ROI)选择肿瘤的平扫、静脉期和延迟期并用以下方法计算廓清率:[(静脉期CT值-延迟期CT值)/(静脉期CT值-平扫CT值)]×100%。根据廓清率的中位数,将所有病例

关键词：

Surgical treatment of hepatocellular carcinoma: Evidence-based outcomes

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World Journal of Gastroenterology 2008年第5期14卷 685-692页

作者： Shintaro yamazaki Tadatoshi takayama Department of Digestive Surgery Nihon University School of Medicine Tokyo 173-8610 Japan

Surgeons may be severely criticized from the perspective of evidence-based medicine because the majority of surgical publications appear not to be convincing. In the top nine surgical journals in 1996, half of the 175 publications refer to pilot studies lacking a control group, 18% to animal experiments, and only 5% to randomized controlled trials (RCT). There are five levels of clinical evidence:level 1 (randomized controlled trial), level 2 (prospective concurrent cohort study), level 3 (retrospective historical cohort study), level 4 (pre-post study), and level 5 (case report). Recently, a Japanese evidence-based guideline for the surgical treatment of hepatocellular carcinoma (HCC) was made by a committee (Chairman, Professor Makuuchi and five members). We searched the literature using the Medline Dialog System with four Keywords:HCC, surgery, English papers, in the last 20 years. A total of 915 publications were identified systematically reviewed. At the first selection (in which surgery-dominant papers were selected), 478 papers survived. In the second selection (clearly concluded papers), 181 papers survived. In the final selection (clinically significant papers), 100 papers survived. The evidence level of the 100 surviving papers is shown here:level-1 papers (13%), level-2 papers (11%), level-3 papers (52%), and level-4 papers (24%);therefore, there were 24% prospective papers and 76% retrospective papers. Here, we present a part of the guideline on the five main surgical issues:indication to operation, operative procedure, peri-operative care, prognostic factor, and post-operative adjuvant therapy.

关键词： Indication to operation Hepatocellular carcinoma Operative procedure Peri-operative care Prognostic factors

2-D localization system utilizing M-sequence encoded laser beam scanning

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仪器仪表学报 2007年第3期28卷 408-413页

作者： Shinji Ohyama Kiyoshi Tanaka Junya takayama Graduate School of Science and Engineering Tokyo Institute of Technology 2-12-1 O-okayama Meguro-ku Tokyo 152-8552 Japan

In this paper, as the active position measurement system, a novel method for a two-dimensional localization system using M-sequence signal is proposed. The feature of this system is to realize a position measurement only by scanning the encoded laser beams from fixing points to a measurement field, and by observing it. First, both the system configuration and encoding method were practically considered, and an order and an initial value of M-sequence signal were selected for encoding. This method is based on discrete angle measurement therefore the resolution has its own limitation. To overcome this limitation, analogue phase shift detecting method was introduced. System design was performed and applied to position measurement experiments. The experimental results show that the measurement error of the analogue method is 1/3 of that of the discrete method.

关键词：激光电子束扫描位置测量二维定位系统 M序列离散法

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Study on fragmentation behavior of taxoids by tandem mass spectrometry

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Chinese Science Bulletin 2000年第8期45卷 688-698页

作者： Zeper Abliz Mitsuo takayama Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical CollegeBeiging 100050.ChinaFaculty of Pharmaceutical SciencesToho University2-2-1 MiyamaFunabashiChiba 274Japan

We have studied the fragmentation behavior of positive and negative ions of taxoi and 6/8/6 type taxoids, the influence of different substituents on fragmentation, and the correlativity between fragmentation patterns and structure by MS/MS technique with different ionization methods such as FAB-MS, ESI-MS, ete. We have also investigated in detail the fragmentation of various molecular-related ions, such as [M+H]+, [M+Na]+ and [M-H] ions, and the formation pathways of characteristic fragment ions. It has been found that there exists some competing reaction between the loss of C-13 side chain and decomposition by loss of acetic acid. In addition, by comparing CID spectra obtained with low- and high-energy collision, it is seen that CID-MS/MS with low-energy collision is more suitable for the study of the structural analysis of small molecules and drug metabolites. The experimental results demonstrate that MS/MS spectra can reflect more effectively the slight difference of structure between the related

关键词： taxol taxoids tandem mass spectrometry fragmentation behavior.

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