检索结果-南通市图书馆

Pancreatic cancer screening in patients with presumed branch-duct intraductal papillary mucinous neoplasms

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Oncology 2019年第2期10卷 67-74页

作者： yuichi Torisu Kazuki takakura yuji Kinoshita yoichi Tomita Masanori Nakano Masayuki Saruta Division of Gastroenterology and Hepatology Department of Internal Medicine The Jikei University School of Medicine

Because delayed diagnosis is one of the causes of poor prognosis in pancreatic ductal adenocarcinoma(PDAC), early detection is a key for overall improvement of prognosis. Towards this end, periodic screening is recommended for individuals considered high-risk for PDAC. Advances in diagnostic imaging modalities have increased the frequency of incidental findings of pancreatic cysts,including the intraductal papillary mucinous neoplasm(IPMN)-a major risk factor of PDAC, having 1% annual prevalence of concomitance with *** retainment of patients with IPMN and regular follow-up by routine imaging examination will likely improve early detection and better prognosis of PDAC. Unfortunately, current guidelines only address management of PDAC derived from IPMN and overlook PDAC concomitant with IPMN. Screening of patients with IPMN, by endoscopic ultrasonography(currently the most reliable modality for detecting small PDAC), may facilitate early detection of both IPMNderived and-concomitant PDAC. Prospective studies to evaluate the usefulness of endoscopic ultrasonography in screening of IPMN-concomitant PDAC will also help in determining the optimal surveillance strategy for more widespread applications.

关键词： Intraductal papillary mucinous neoplasm Pancreatic ductal adenocarcinoma Endoscopic ultrasonography Screening Early diagnosis

Production of corticotropin-releasing factor and urocortin from human monocyte-derived dendritic cells is stimulated by commensal bacteria in intestine

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第39期20卷 14420-14429页

作者： Shigeo Koido Toshifumi Ohkusa Shin Kan Kazuki takakura Keisuke Saito Hideo Komita Zensho Ito Hiroko Kobayashi Shinichiro Takami Kan Uchiyama Hiroshi Arakawa Masaki Ito Masato Okamoto Mikio Kajihara Sadamu Homma Hisao Tajiri Division of Gastroenterology and Hepatology Department of Internal Medicine The Jikei University School of Medicine Chiba 277-8567 Japan Department of Oncology The Jikei University School of Medicine Tokyo 105-8461 Japan Department of Advanced Immunotherapeutics Kitasato University School of Pharmacy Tokyo 108-8641 Japan

AIM: To examine whether commensal bacteria are a contributing cause of stress-related mucosal inflammation.

关键词： Commensal bacteria Corticotropin-releasing factor Dendritic cell Irritable bowel syndrome Inflammatory bowel disease Urocortin

Combined Onset of Bilateral Endophthalmitis and Spondylodiscitis as Manifestations of <i>Streptococcus dysgalactiae</i>Infection in an Elderly Woman

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Case Reports in Clinical Medicine 2014年第4期3卷 216-219页

作者： Kazuki takakura Mikio Kajihara Ryoko Fukushima Seiji Arihiro Shigeo Koido Hisao Tajiri Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan

A case of a patient with bilateral endophthalmitis and vertebral infection is presented here. The case presented with fever, general malaise, reduced vision and back pain for at least two weeks. Diagnosis was established by positive blood cultures together with ophthalmology review and radiological findings. Streptococcus dysgalactiae subspecies equisimilis was isolated from blood cultures. This case demonstrates the risks for older patients of developing invasive disease upon exposure to Streptococcus dysgalactiae, even if underlying diseases are absent.

关键词： Bilateral Endophthalmitis Spondylodiscitis Streptococcus dysgalactiae

Electrochemical Tuning by Polarized UV Light Induced Molecular Orientation of Chiral Salen-type Mn（II） and Co（II） Complexes in an Albumin Matrix

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Chemistry and Chemical Engineering 2016年第2期10卷 53-59页

作者： Eirika Tsuda yuya Mitsumoto Kazuya takakura Nobumitsu Sunaga Takashiro Akitsu Taro Konomi Masahiro Katoh Department of Chemistry Faculty of Science Tokyo University of Science 1-3 Kagurazaka Shinjuku-ku Tokyo 162-8601 Japan UVSOR Institute for Molecular Science 38 Nishigonaka Myodaiji OkazakL Aichi 444-8585 Japan

The authors have prepared supramolecular systems as artificial metalloproteins composed of several chiral salen-type Mn（II） and Co（II） complexes in a HSA （human serum albumin） matrix. The docking was discussed by UV-vis spectral changes and a ligand-protein docking simulation program. After linearly polarized UV light irradiation, that anisotropy of molecular orientation of the complexes increased was confirmed by polarized IR spectra. The authors have observed that the electrochemical behavior of the aligned complexes incorporating diphenyl groups in HSA can be tuned without UV radiation damage of HSA higher structures.

关键词： Redox potential Schiff base Mn(II) complex Co(II) complex albumin.

Miniature Amorphous Silicon Solar Cells Activated by Laser for Power Sources of Micromachines

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Miniature Amorphous Silicon Solar Cells Activated by Laser f...

第十五届国际光伏科学与工程大会

作者： Takeshi Kitaura yoichirou Suzuki Takashi Minemoto Hideyuki takakura yoshihiro Hamakawa College of Science and Engineering Ritsumeikan University 1-1-1 NojihigashiKusatsu Shiga 525-8577 Japan

Miniature integrated solar cells for power sources of micromachines, such as sensors and actuators were fabricated. For the power supply of autonomous operation, such as free-moving micro robotic systems and space-based systems, a self-contained on-board or remote power supply is desirable. The systems of power supply must consume as small an area as possible to minimize the overall size of the system and output high voltage. In this work, The miniature integrated solar cells based on amorphous Si (a-Si) with the area of 2.5 mm consisted of 2 unit cells series connected were fabricated using a photolithography technique. The current-voltage characteristic of the solar cell under He-Ne laser (λ=632.8 nm) with the power of 1.6-6.4 mW were measured. With the laser power 6.4 mW, the solar cell produced a highest output voltage of 1.88 V and the power of 0.74 mW. In contrast to the output power, a highest efficiency of 18%, which is more than twice greater than that operated under sunlight, was obtained with the laser power of 1.6 mW. These results showed the usefulness of miniature amorphous silicon solar cells activated by laser for power sources of micromachines.

关键词： Solar Cell Amorphous Si Micromachine He-Ne Laser

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

计算机控制的演播摄象机图象质量高

光电子技术 1987年第3期 80-84页

作者： Kazuo takakura 陈吟

随着计算机技术的飞速进步,现在已经有一代在摄象系统中起主导作用的计算机.本文将介绍用于演播摄象机的计算机,着重介绍自动设定技术.

关键词：摄象机自动设定 SCU 图象质量 RCU 传感器计算机控制电脑控制场存储器

EVALUATION ON AN INFLUENCE TO TURBINE GENERATOR INSTALLED ON A CONCRETE FOUNDATION STRUCTURE AFFECTED By ALKALI-SILICA REACTION

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

EVALUATION ON AN INFLUENCE TO TURBINE GENERATOR INSTALLED ON...

Development of "Real-Time" Navigation System Updated with Intraoperative MR Imaging for Total Removal of Glioma

第十三届国际核工程大会

作者： Takeo takakura yoshihisa Asai Takashi Hosokawa Takashi Momoo Shigeru Harada Mitsubishi Heavy Industries Ltd. Shikoku Electric Power Co. Inc. Mitsubishi Heavy Industries Ltd.

1 INTRODUCTION Turbine-Generator examined in this report has been installed on reinforced concrete support structure.A deferent machine setting value with the original setting value set on during c

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Development of "Real-Time" Navigation System Updated with In...

Advances in inducing adaptive immunity using cell-based cancer vaccines: clinical applications in pancreatic cancer

The 6th International Conference on Biomedical Engineering and Rehabilitation Engineering

作者： yoshihiro Muragaki Iseki Hiroshi Takashi Maruyama Masahiko Tanaka Osami Kubo Kintomo takakura Tomokatsu Hori Department of Neurosurgery Neurological InstituteTokyo Women’s Medical University.8-1 Kawada-cho Shinjuku-ku Tokyo 162-8666 Department of Neurosurgery Neurological InstituteTokyo Women’s Medical University.8-1 Kawada-cho Shinjuku-ku Tokyo 162-8666 Department of Neurosurgery Neurological InstituteTokyo Women’s Medical University.8-1 Kawada-cho Shinjuku-ku Tokyo 162-8666 Department of Neurosurgery Neurological InstituteTokyo Women’s Medical University.8-1 Kawada-cho Shinjuku-ku Tokyo 162-8666 Department of Neurosurgery Neurological InstituteTokyo Women’s Medical University.8-1 Kawada-cho Shinjuku-ku Tokyo 162-8666 Department of Neurosurgery Neurological InstituteTokyo Women’s Medical University.8-1 Kawada-cho Shinjuku-ku Tokyo 162-8666 Department of Neurosurgery Neurological InstituteTokyo Women’s Medical University.8-1 Kawada-cho Shinjuku-ku Tokyo 162-8666

＜正＞ The extent of operative removal in glioma is statistically correlated with patient’sprognosis, however, its complex shape often cause incomplete removal. Various navigationsystems are not useful by becoming outdated for the brain shift. We report the developmentand initial experience of new "real-time" navigation system （RTnavi） updated with

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2016年第18期22卷 4446-4458页

作者： Mikio Kajihara Kazuki takakura Tomoya Kanai Zensho Ito yoshihiro Matsumoto Shigetaka Shimodaira Masato Okamoto Toshifumi Ohkusa Shigeo Koido Division of Gastroenterology and Hepatology Department of Internal Medicine the Jikei University School of Medicine (Kashiwa Hospital) Cell Processing Center Shinshu University Hospital Department of Advanced Immunotherapeutics Kitasato University School of Pharmacy Institute of Clinical Medicine and Research The Jikei University School of Medicine

The incidence of pancreatic ductal adenocarcinoma(PDA) is on the rise, and the prognosis is extremely poor because PDA is highly aggressive and notoriously difficult to treat. Although gemcitabine- or 5-fluorouracil-based chemotherapy is typically offered as a standard of care, most patients do not survive longer than 1 year. Therefore, the development of alternative therapeutic approaches for patients with PDA is imperative. As PDA cells express numerous tumor-associated antigens that are suitable vaccine targets, one promising treatment approach is cancer vaccines. During the last few decades, cell-based cancer vaccines have offered encouraging results in preclinical studies. Cell-based cancer vaccines are mainly generated by presenting whole tumor cells or dendritic cells to cells of the immune system. In particular, several clinical trials have explored cell-based cancer vaccines as a promising therapeutic approach for patients with PDA. Moreover, chemotherapy and cancer vaccines can synergize to result in increased efficacies in patients with PDA. In this review, we will discuss both the effect of cell-based cancer vaccines and advances in terms of future strategies of cancer vaccines for the treatment of PDA patients.

关键词： Pancreatic cancer Dendritic cell whole tumor cell Cancer vaccine Cytotoxic T lymphocyte