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Bone Research 2024年第1期12卷 122-136页

作者： Nan-yu Zou Ran Liu Mei Huang yu-Rui jiao jie Wei yangzi jiang Wen-Zhen He Min Huang yi-Li xu Ling Liu yu-chen Sun Mi yang qi Guo yan Huang tian Su ye xiao Wei-Shan Wang Chao zeng Guang-Hua Lei xiang-Hang Luo Chang-jun Li Department of Endocrinology Endocrinology Research CenterXiangya Hospital of Central South UniversityChangshaHunan 410008China Department of Orthopaedics Xiangya Hospital of Central South UniversityChangshaHunan 410008China Department of Epidemiology and Health Statistics Xiangya School of Public HealthCentral South UniversityChangshaChina Hunan Key Laboratory of joint Degeneration and Injury ChangshaHunan 410008China Key Laboratory of Aging-related Bone and joint Diseases Prevention and treatment Ministry of EducationXiangya HospitalCentral South UniversityChangshaChina School of Biomedical Sciences Institute for Tissue Engineering and Regenerative MedicineFaculty of MedicineThe Chinese University of Hong KongHong Kong SARChina Department of Orthopaedics The First Affiliated Hospital of Shihezi UniversityShiheziXinjiangChina National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangshaHunan 410008China

Skeletal stem/progenitor cell(SSPC)senescence is a major cause of decreased bone regenerative potential with aging,but the causes of SSPC senescence remain *** this study,we revealed that macrophages in calluses secrete prosenescent factors,including grancalcin(GCA),during aging,which triggers SSPC senescence and impairs fracture *** injection of human rGCA in young mice induced SSPC senescence and delayed fracture *** deletion of Gca in monocytes/macrophages was sufficient to rejuvenate fracture repair in aged mice and alleviate SSPC ***,GCA binds to the plexin-B2 receptor and activates Arg2-mediated mitochondrial dysfunction,resulting in cellular *** of Plxnb2 in SSPCs impaired fracture *** of GCA-neutralizing antibody enhanced fracture healing in aged ***,our study revealed that senescent macrophages within calluses secrete GCA to trigger SSPC secondary senescence,and GCA neutralization represents a promising therapy for nonunion or delayed union in elderly individuals.

关键词： healing union senescence

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Deep learning-assisted common temperature measurement based on visible light imaging

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Chinese Physics B 2024年第8期33卷 230-236页

作者：朱佳仪何志民黄成曾峻林惠川陈福昌余超群李燕张永涛陈焕庭蒲继雄 College of Physics and Information Engineering Minnan Normal UniversityZhangzhou 363000China fujian Provincial Key Laboratory of Light Propagation and transformation College of Information Science&EngineeringHuaqiao UniversityXiamen 361021China

Real-time,contact-free temperature monitoring of low to medium range(30℃-150℃)has been extensively used in industry and agriculture,which is usually realized by costly infrared temperature detection *** paper proposes an alternative approach of extracting temperature information in real time from the visible light images of the monitoring target using a convolutional neural network(CNN).A mean-square error ofthe temperature measurements of low to medium range using the CNN and the visible light *** angle and imaging distance do not affect the temperature detection using visible optical images by the ***,the CNN has a certain illuminance generalization ability capable of detection temperature information from the images which were collected under different illuminance and were not used for *** to the conventional machine learning algorithms mentioned in the recent literatures,this real-time,contact-free temperature measurement approach that does not require any further image processing operations facilitates temperature monitoring applications in the industrial and civil fields.

关键词： convolutional neural network visible light image temperature measurement low-to-medium-range temperatures

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On the mechanism of Si-promoted destabilization of tiC_(x)particles in Al alloys

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journal of Materials Science & technology 2023年第34期165卷 17-26页

作者： H.Dong y.C.Guo y.Z.chen f.xia q.q.Guo q.chen G.L.Li j.y.Zhao y.Zhong j.P.Li School of Materials and Chemical Engineering Xi’an Technological UniversityXi’an 710021China State Key Lab.of Solidification Processing Northwestern Polytechnical UniversityXi’an 710072China School of Science Xi’an University of Science and TechnologyXi’an 710054China

tiC_(x)is an excellent composite strengthening particle and grain refiner for Al ***,the stability of tiC_(x)is poor when solute Si exists in Al alloy melts,which significantly depresses its strengthening and grain refining *** this work,the destabilization mechanisms of the tiC_(x)particles in Al-Si alloy melt with a composition of Al-7Si-7.5tiC were explored via experiments,first-principles calculations and thermodynamic *** experimental results show that Si atoms diffuse into tiC_(x)and ti atoms are released into the Al melt to form a ti-rich transition zone during the insulation of tiC_(x)in Al-Si melt,and the tiAlySiz and Al_(4)C_(3)phases are solidified in the ti-rich zone and at ti-rich zone/tiC_(x)interface,*** first principles calculations show that the low formation energy of C vacancies facilitates the rapid diffusion of Si atoms in tiC_(x),while the doping of Si atoms reduces the energy barrier of diffusion of ti atoms in tiC_(x)and promotes the formation of ti-rich *** thermodynamic calculations show that the wide crystallization temperature range of the destabilized product tiAlySiz phase is the key to continuous decomposition of tiC_(x)*** addition,the driving force of the main destabilization reaction of tiC_(x)in the Al-Si alloys is about 44 times higher than that in the Al alloys without Si *** indicates that the presence of solute Si remarkably promotes the subsequent decomposition process of tiC_(x)in the Al-Si alloy melts.

关键词： Al-Si alloy tiC_(x)particles Destabilization first principles calculations thermodynamics

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Novel transcatheter aortic heart valves exhibiting excellent hemodynamic performance and low-fouling property

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journal of Materials Science & technology 2019年第1期35卷 207-215页

作者： f.Guo K.jiao y.Bai j.Guo q.chen R.yang x.Zhang Shenyang National Laboratory for Materials Science Institute of Metal Research Chinese Academy of Sciences School of Materials Science and Engineering University of Science and Technology of China School of textile and Material Engineering Dalian Polytechnic University Lumenous Peiertech

transcatheter aortic heart valves(tAHVs) have been widely used for aortic valve replacements, with less trauma and lower clinical risk compared with traditional surgical heart valve replacements. In the present study, composites of poly(ethylene glycol) diacrylate(PEGDA) hydrogels and anisotropic highshrinkage polyethylene terephthalate/polyamide6(PEt-PA6) fabric(PEGDA/PEt-PA6) were fabricated as artificial heart valve leaflets. Dynamic mechanical analyses(DMA) indicated that PEGDA/PEt-PA6 composites possessed anisotropic mechanical properties(i.e., storage moduli ~23.30 ± 1.36 MPa parallel to the aligned fabric fibers and ~9.68 ± 0.90 MPa perpendicular to the aligned fibers at 1 Hz) that were comparable to aortic valve leaflets. the PEGDA/PEt-PA6 composites with smooth surfaces were highly hydrophilic(contact angle ~41.6°± 3.8°) and had low-fouling properties without platelet adhesion,suggesting a low risk of thrombogenicity when they interacted with blood. furthermore, transcatheter aortic heart valves were fabricated using nitinol self-expanding frames and PEGDA/PEt-PA6 composites as artificial leaflets, which presented excellent hemodynamic performance with a large orifice area(1.75cm2) and low regurgitation(3.41%), thus meeting the requirements of ISO 5840-3 standard. therefore,PEGDA/PEt-PA6 composites had suitable mechanical properties, good biocompatibility, and low-fouling properties, indicating that they might be used for tAHVs in the future.

关键词： transcatheter aortic heart valve textile fabric Poly(ethylene glycol)diacrylate Anti-fouling

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the effects of fabrication atmosphere condition on the microstructural and mechanical properties of laser direct manufactured stainless steel 17-4 PH

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journal of Materials Science & technology 2019年第7期35卷 1315-1322页

作者： D.Wang C.t.Chi W.q.Wang y.L.Li M.S.Wang x.G.chen Z.H.chen x.P.cheng y.j.xie Institute of Applied Physics Jiangxi Academy of SciencesNanchang 330029China Institute of Metal Research Chinese Academy of SciencesShenyang 110016China School of Mechanical and Electrical Engineering Nanchang UniversityNanchang 330029China jiangxi Reman Additive technology Co. Ltd Nanchang 330096China

the effects of atmosphere conditions on microstructural and mechanical properties of stainless steel 17-4PH components fabricated by laser direct manufacturing (LDM) were investigated through mea-surements on phase constitution, porosity, tensile strength, fracture morphology, hardness and evolution of substrate temperature. Results showed that the samples produced in air atmosphere condition pos-sessed higher tensile strength and hardness for both as-deposited and heat-treated states than that in Ar chamber condition, due to dispersion strengthening effect of amorphous oxide particles and nitrogen solution strengthening as a result of higher content of oxygen and nitrogen. the temperature of substrate heat accumulation was higher in Ar chamber condition, leading to dramatically lower porosity and more reverse austenite, which also contributed to the lower strength and hardness.

关键词： Additive manufacturing Laser direct manufacturing 17-4 PH stainless steel fabrication atmosphere Mechanical properties

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An efficient SPH methodology for modelling mechanical characteristics of particulate composites

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Defence technology（防务技术） 2021年第1期17卷 135-146页

作者： Z.j.Zheng S.Kulasegaram P.chen y.q.chen Department of Mechanics College of Mechanical EngineeringChongqing University of TechnologyChongqing400054China Institute of Applied and Computational Mechanics Cardiff School of EngineeringCardiff UniversityQueen’s BuildingsThe ParadeCardiffCF243AAWalesUK Department of Mechanics and Engineering Science College of EngineeringPeking UniversityBeijing100871China

Particulate composites are one of the widely used materials in producing numerous state-of-the-art components in biomedical,automobile,aerospace including defence *** of modelling techniques have been adopted in the past to model mechanical behaviour of particulate *** to their favourable properties,particle-based methods provide a convenient platform to model failure or fracture of these *** particle hydrodynamics(SPH)is one of such methods which demonstrate excellent potential for modelling failure or fracture of particulate composites in a Lagrangian *** of the major challenges in using SPH method for modelling composite materials depends on accurate and efficient way to treat interface and boundary *** this paper,a masterslave method based multi-freedom constraints is proposed to impose essential boundary conditions and interfacial displacement constraints in modelling mechanical behaviour of composite materials using SPH *** proposed methodology enforces the above constraints more accurately and requires only smaller condition number for system stiffness matrix than the procedures based on typical penalty function approach.A minimum cut-off value-based error criteria is employed to improve the computational efficiency of the proposed *** addition,the proposed method is further enhanced by adopting a modified numerical interpolation scheme along the boundary to increase the accuracy and computational *** numerical examples demonstrate that the proposed master-slave approach yields better accuracy in enforcing displacement constraints and requires approximately the same computational time as that of penalty method.

关键词： Particulate composites SPH Essential boundary condition Multi-point constraints Master-slave method

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Unveiling anneal hardening in dilute Al-doped Al_(x)CoCrfeMnNi(x = 0,0.1) high-entropy alloys

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journal of Materials Science & technology 2021年第32期91卷 270-277页

作者： q.cheng x.D.xu P.xie L.L.Han j.y.He x.q.Li j.Zhang Z.t.Li y.P.Li B.Liu t.G.Nieh M.W.chen j.H.chen Centre for High Resolution Electron Microscopy College of Materials Science and EngineeringHunan UniversityChangsha 410082China State Key Laboratory of Powder Metallurgy Central South UniversityChangsha 410083China Applied Materials Physics Department of Materials Science and EngineeringKTH-Royal Institute of TechnologyStockholm SE10044Sweden Department of Materials Science and Engineering University of TennesseeKnoxvilleTN37996United States Department of Materials Science and Engineering Johns Hopkins UniversityBaltimoreMD 21214USA

Anneal hardening has been one of the approaches to improve mechanical properties of solid solution alloys with the face-centered cubic(fCC) structure,whereby a considerable strengthening can be attained by annealing of cold-worked alloys below the recrystallization temperature(t_(rx)).Microscopically,this hardening effect has been ascribed to several mechanisms,*** segregation to defects(dislocation and stacking fault) and short-range chemical ordering,***,none of these mechanisms can well explain the anneal hardening recently observed in phase-pure and coarse-grained fCC-structured high-entropy alloys(HEAs).Here we report the observations,using high-resolution electron channeling contrast imaging and transmission electron microscopy,of profuse and stable dislocation substructures in a cold-rolled CoCrfeMnNi HEA subject to an annealing below t_(rx).the dislocation substructures are observed to be thermally stable up to t_(rx),which could arise from the chemical complexity of the high-entropy system where certain elemental diffusion retardation *** microstructure feature is markedly different from that of conventional dilute solid solution alloys,in which dislocation substructures gradually vanish by recovery during annealing,leading to a strength ***,dilute addition of 2 at.% Al leads to a reduction in both microhardness and yield strength of the cold-rolled and subsequently annealed(≤500℃) *** Al induced softening effect,could be associated with the anisotropic formation of dislocation substructure,resulting from enhanced dislocation planar slip due to glide plane softening *** findings suggest that the strength of HEAs can be tailored through the anneal hardening effect from dislocation substructure strengthening.

关键词： Annealing hardening Dislocation substructure strengthening High-entropy alloy Solid solution structure

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MICROStRUCtURE AND MECHANICAL PROPERty DEVELOPMENt IN tHE SIMULAtED HEAt AffECtED ZONE Of V tREAtED HSLA StEELS

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Acta Metallurgica Sinica(English Letters) 2006年第1期19卷 57-67页

作者： y. t. chen A.M. Guo L.x. Wu j. zeng P.H. Li National Enterprise technology Center Wuhan Iron and Steel （Group） Co.Wuhan 430080 China

the simulated heat affected zone （HAZ） of the high strength low alloy （HSLA） steels containing 0%, 0.047%, 0.097% and 0.151% vanadium, respectively, were studied with Gleeble-2000 thermomechanical simulator to determine the influence of vanadium addition on the mechanical properties of the HAZ. the HAZ simulation involved reheating the samples to 1350℃, and then cooling to ambient temperature at a cooling rate of 5℃/s ranging from 800 to 500℃ （△8/5=60s）. the mechanical properties including tensile strength and -20℃ impact toughness were conducted. the microstructures of the base steel and the simulated HAZs were investigated using optical microscope, scanning electron microscope （ SEM ） and transmission electron microscope （tEM）. Based on the systemutic examination, the present work confirmed that about 0.05% vanadium addition to low carbon low alloy steels resulted in expected balance of strength and toughness of the HAZ. And more than 0.10% levels addition led to detrimental toughness of the HAZ SEM study showed that the simulated 0.097% and 0.151%V HAZs consisted of more coarse ferrite plates with greater and more M-A constituents along austenite grain and ferrite plate bound- aries. the impact fracture surfaces of the simulated 0.097% and 0.151%V HAZs showed typically brittle mode with predominant cleavages. the size of the facet in the fracture surface increased with increasing vanadium level from 0.097% to 0.151%.As a result, the simulated 0.151% V HAZ has the lowest impact toughness of the four specimens.

关键词： vanadium high strength low alloy (HSLA) steel mechanical property,heat affected zone (HAZ)

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INtERfACIAL DEBONding Of fRC UNDER CyCLIC LOAding

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Acta Metallurgica Sinica(English Letters) 2004年第3期17卷 327-330页

作者： q.j.Zhu y.H.chen j.chen Department of Civil Engineering Hebei Institute of Technology Tangshan 063009 China School of Civil Engineering Beijing Jiaotong University Beijing 100044 ChinaDepartment of Civil Engineering Hebei Institute of Technology Tangshan 063009 China

With the increasingly use of fRC (fiber-reinforced composite) in urban lifelines, me-chanical properties investigation is very important for disaster resistance, especiallythe investigation of fatigue properties. Based on the shear-lag model, an usual com-posite model under cyclic loading is established. According to the Paris formula, therelationship between interfacial fatigue parameters and the number of cycles is ob-tained under the cyclic loading. Interfocial fatigue properties of this model and thegrowth of the interfacial fatigue crack are analyzed. And the Poisson ratio is consid-ered also.

关键词： interfacial debonding fiber matrix cyclic loading crack growth

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three principles for preparing Al wire with high strength and high electrical conductivity

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journal of Materials Science & technology 2019年第5期35卷 742-751页

作者： j.P.Hou R.Li q.Wang H.y.yu Z.j.Zhang q.y.chen H.Ma x.M.Wu x.W.Li Z.f.Zhang Materials fatigue and fracture Division Shenyang National Laboratory for Materials Science Institute of Metal Research Chinese Academy of Sciences Shenyang 110016 China National quality Supervision & Inspection Center of Electrical Equipment Safety Performance Zhejiang Huadian Equipment Testing Institute Hangzhou 310015 China Electric Power Research Institute of Liaoning Electric Power Co. Ltd. Liaoning Electric Power Co. Ltd. Shenyang 110006 China Department of Materials Physics and Chemistry School of Materials Science and Engineering Key Laboratory for Anisotropy and Texture of Materials Ministry of Education Northeastern University Shenyang 110819 China

the trade-off relation between the strength and the electrical conductivity has been a Iong-standing dilemma in metallic materials. In the study, three key principles, *** grains, sharp texture and nano-scale precipitates, were presented for preparing Al wire with high strength and high electrical conductivity based on the specially designed experiments for breaking the mutually exclusive relation between the strength and the electrical conductivity. the results show that the elongated grains could lead to a higher electrical conductivity in Al wire without sacrificing the strength;while, the sharp texture can efficiently strengthen the Al wire without influencing the electrical conductivity. furthermore, nano-scale precipitates with proper size can simultaneously improve the strength and electrical conductivity of Al alloy wire. Under the guidance of the above three key principles, Al wires with high strength and high conductivity were prepared.

关键词： Al wire texture Precipitates Strength Electrical conductivity

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